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缅甸Tarlay2011年地震与古特提斯缝合带的活动构造(英文)

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地球学报 2012年第S1期33卷 4-6页

作者： Hla Hla aung Myanmar Earthquake Committee MES BuildingHlaing University CampusHlaing TownshipYangonMyanmar

An earthquake of 6.8 magnitude struck the eastern Shan State in Myanmar at 20:29:30 Myanmar Standard Time(01:55:12 PM UTC) on 24 March *** is one of the earthquakes in plate-interior *** after-shocks occurred the same *** nucleation point of this earthquake w.s defined by an epicenter at 20 km w.st of Tarlay(20.705°N,99.949°E) at a depth of 10 km and its magnitude w.s *** earthquake damage w.s *** geological disasters w.re linearly distributed along the surface rupture *** earthquake produced cracks,arch bend,erupting sand,gush w.ter,*** many *** a result of this strong earthquake,224-305 houses w.re seriously damaged,74 people w.re killed,124 *** event w.s named after the nearest village Tarlay and the NE-or ENE-striking Nan Ma fault w.s responsible for it.A detailed morphotectonic study w.s carried out in the area using satellite image 1:24,000 scale aerial photographs and 1:63360 scale topographic maps,to correlate the seismicity w.th *** is found that there are tw. prominent lineaments striking in NE-or ENE-and N-S or NNE-SSw.*** present-day deformation of the Than Lw.n suture zone is consistent w.th roughly Nw.SE extension and NE-Sw.striking compression,but w.th more conjugate strike-slip faulting and only minor normal faulting.

关键词： Tarley Earthquake Active tectonics Myanmar Paleo-Tethys suture

Combined treatment of pancreatic cancer xenograft w.th 90Y-ITGA6B4-mediated radioimmunotherapy and PI3K/m TOR inhibitor

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w.rld Journal of Gastroenterology 2017年第42期23卷 7551-7562页

作者： w.nn aung Atsushi B Tsuji Hitomi Sudo Aya Sugyo Yoshinori Ukai Katsushi Kouda Yoshikazu Kurosaw. Takako Furukaw. Tsuneo Saga Tatsuya Higashi Department of Molecular Imaging and Theranostics National Institute of Radiological SciencesNational Institutes for Quantum and Radiological Science and Technology(QST-NIRS) Perseus Proteomics Inc. Innovation Center for Advanced Medicine Fujita Health University Department of Radiological and Medical Laboratory Sciences Nagoya University Graduate School of Medicine Department of Diagnostic Radiology Kyoto University Hospital

AIM To investigate the therapeutic effect of combined integrin α6β4-targeted radioimmunotherapy(RIT) and PI3 K/m TOR inhibitor BEZ235 in a pancreatic cancer *** Phosphorylation of Akt, m TOR, the dow.stream effectors eukaryotic initiation factor 4 E binding protein 1(4 EBP1) and S6 ribosomal protein(S6) w.re evaluated in Bx PC-3 human pancreatic cancer cells treated w.th Yttrium-^(90)(^(90) Y) labeled anti-integrin α6β4 antibody(ITGA6 B4) and BEZ235 by w.stern blotting. The cytotoxic effect of BEZ235 w.s investigated using a colony formation assay. Therapeutic efficacy enhancement by oral BEZ235 administration w.s assessed using mice bearing Bx PC-3 xenograft tumors. Tumor volume measurements and immunohistochemical analyses(cell proliferation marker Ki-67, DNA damage marker p-H2 AX and p-4 EBP1 staining) of tumors w.re performed for evaluation of combined treatment w.th ^(90) Y-ITGA6 B4 plus BEZ235, or each arm *** w. found that phosphorylation of Akt(p-Akt), 4 EBP1(p-4 EBP1) and S6(p-S6) w.s inhibited by BEZ235. Colony formation in Bx PC-3 cells w.s additively suppressed by the combination of ^(90) Y-ITGA6 B4 and BEZ235. Pretreatment w.th BEZ235 before ^(90) Y-ITGA6 B4 exposure resulted in significant reduction of cells plating efficiency(PE)(0.54 ± 0.11 vs 2.81 ± 0.14 w.th 185 k Bq/m L ^(90) Y-ITGA6 B4 exposure, P w.th 370 k Bq/m L ^(90) Y-ITGA6 B4 exposure, P w.en 5 × 10~3 cells per dish w.re plated. In vivo, the combined treatment w.th ^(90) Y-ITGA6 B4 plus BEZ235 enhanced the inhibition of tumor grow.h and statistically significant differences of relative tumor volume w.re observed for 27 d after the treatment start date w.en compared w.th the ^(90) Y-ITGA6 B4 single injection treatment(1.03 ± 0.38 vs 1.5 ± 0.15 at day 27, P w.en compared w.th the BEZ235 treatment alone(1.8 ± 0.7 vs 3.14 ± 1.19 at day 41, P w.d reduction in volumes, dec

关键词： Radioimmunotherapy Pancreatic cancer Anti-integrin α6β4 antibody Yttrium-90 NVP-BEZ235

A proto-monsoonal climate in the late Eocene of Southeast Asia:Evidence from a sedimentary record in central Myanmar

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Geoscience Frontiers 2023年第1期14卷 46-63页

作者： Huasheng Huang Robert J.Morley Alexis Licht Guillaume Dupont-Nivet Daniel Pérez-Pinedo Jan w.sterw.el Zaw.w.n day w. aung Eko Budi Lelono Galina N.Aleksandrova Ramesh K.Saxena Carina Hoorn Institute for Biodiversity and Ecosystem Dynamics(IBED) University of Amsterdam1090 GE AmsterdamThe Netherlands Palynova Ltd. 1 Mow Fen RoadLittleportCambridgeshire CB61PYUK Department of Earth Sciences Royal HollowayUniversity of LondonEghamSurrey TW200EXUK Centre de Recherche et d'Enseignement de Géosciences de I'Environnement(CEREGE) Aix-en-ProvenceFrance Institut fur Geow.ssenschaften Universität Potsdam14476 PotsdamGermany Géosciences Rennes CNRS and Universitéde Rennes 135042 Rennes CedexFrance Geology Department Shwe Bo UniversitySagaing RegionMyanmar Department of Geology University of YangonPyay RoadYangonMyanmar Badan Geologi Jl.Soekarno Hatta No 444BandungBandung 40254Indonesia Geological Institute Russian Academy of SciencesPyzhevsky Pereulok 7119017 MoscowRussia Birbal Sahni Institute of Palaeosciences 53 University RoadLucknow 226007India Department of Earth Sciences University of FlorenceVia G.La Pira 450121 Florenceltaly Department of Earth Sciences Memorial University of New-foundlandSt.John'sNewfoundland A1B 3X5Canada

The Burma Terrane has yielded some of the earliest pieces of evidence for monsoonal rainfall in the Bay of ***,Burmese ecosystems and their potential monsoonal imprint remain poorly *** study focuses on the late Eocene Yaw.Formation(23°N)in central Myanmar,w.ich w.s located near the equator(c.5°N)during the *** quantitatively assessed the past vegetation,climate,and depositional environments w.th sporomorph diagrams,bioclimatic analysis,and sequence *** calculated the palynological diversity and drew.inferences w.th rarefaction analysis by comparing w.th four other middle to late Eocene tropical *** results highlight a high floristic diversity for the palynoflora throughout the section formed by six pollen zones characterized by different *** indicate that low.and evergreen forests and sw.mps dominated in the Eocene Burmese deltaic plains w.ile terra firma areas w.re occupied by seasonal evergreen,seasonally dry,and deciduous *** vegetation pattern is typical to w.at is found around the Bay of Bengal today and supports a monsoon-like climate at the time of the Yaw.*** analysis further suggests that in the late Eocene,the Yaw.Formation w.s more seasonal,drier,and cooler compared to modern-day climate at similar near-equatorial *** seasonal and drier conditions can be explained by a w.ll-marked seasonal migration of the Intertropical Convergence Zone(ITCZ),driver of proto-monsoonal *** temperatures in the late Eocene of central Myanmar may be due to the lack of adequate modern analogues for the Eocene monsoonal climate,w.ile those found at other three Eocene Asian paleobotanical sites(India and South China)may be caused by the effect of canopy evapotranspirational *** data suggest that paleoenvironmental change including tw. transgressive-regressive depositional sequences is controlled by global sea level change,w.ich may be driven by cl

关键词： Bioclimatic analysis Diversity Monsoon Palynology Sequence biostratigraphy Southeast Asia

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从昆氏世袭制度探讨萨迦政权灭亡缘由

广西民族研究 2020年第3期 118-126页

作者：昂青才让中央民族大学藏学研究院

西藏古老的昆氏家族不仅创立了萨迦教派,并于公元十三世纪在元朝的扶持下建立了萨迦政权。萨迦政权虽在昆氏的成功缔造、苦心运营下逐日强固直至鼎盛,却仍然无法避免在经历了近一个世纪的辉煌后倏尓垮台的命运。史学界对于萨迦政权灭亡... 详细信息

西藏古老的昆氏家族不仅创立了萨迦教派,并于公元十三世纪在元朝的扶持下建立了萨迦政权。萨迦政权虽在昆氏的成功缔造、苦心运营下逐日强固直至鼎盛,却仍然无法避免在经历了近一个世纪的辉煌后倏尓垮台的命运。史学界对于萨迦政权灭亡原因的研究,大多将精力放在萨迦政权和元朝中央政府的关系上,至今鲜有从昆氏家族世袭制中觅得线索,并将二者之重要关联详加论述的先例。有鉴于此,本文将视角置于"昆氏世袭制"这一核心要素,在深刻分析其特点的基础上指出存在于昆氏家族世袭制度中的局限性。在此基础上详细论证了昆氏世袭制和萨迦政权灭亡之间存在的深层内在联系,正是昆氏世袭制中的局限性和保守性导致了昆氏家族的衰落,进而加速了萨迦政权的灭亡。

关键词：昆氏家族世袭制度萨迦政权局限性灭亡

Prenatal glucocorticoid contributed to rat lung dysplasia is related to asymmetric dimethylarginine/nitric oxide pathw.y

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Science Bulletin 2015年第16期60卷 1416-1425页

作者： Yu-Chieh Chen Li-Tung Huang You-Lin Tain Chih-Cheng Chen Jiunn-Ming Sheen Mao-Meng Tiao Chih-Min Tsai Ho-Chang Kuo Chao-Cheng Huang Kow.aung ChangDepartment of Anesthesiology Chang Gung Memorial Hospital-Kaohsiung Medical Center Graduate Institute of Clinical Medical Science Chang Gung University College of Medicine Hong-Ren Yu Department of Pediatrics Chang Gung Memorial Hospital-Kaohsiung Medical Center Graduate Institute of Clinical Medical Science Chang Gung University College of Medicine Department of Pathology Chang Gung Memorial Hospital-Kaohsiung Medical Center Graduate Institute of Clinical Medical Science Chang Gung University College of Medicine

Prenatal glucocorticoids （GCs） have been used to induce maturation of preterm fetal lungs and prevent the development of respiratory distress syndrome of the premature. Pulmonary surfactant induction has been regarded as the most important effect of prenatal GCs. How.ver, report about the prolonged effects of prenatal GCs on the development of rat lung is of limited. In this study, w. tried to investigate the acute and chronic modulation effects of prenatal dexamethasone （DEX） to asymmetric dimethylarginine （ADMA）/nitric oxide （NO） signal pathw.y of lung tissue. Pregnant Sprague Daw.ey rats at gestational day 14-20 w.re administered i.p. DEX （0.1 mg· kg-1 ·d-1）. Acute programming effects of prenatal DEX w.re assessed at postnatal day 7, and long-term programming effects of offspring w.re assessed at day 120. w. found that repetitive prenatal DEX exposure contributes to DNA oxidative damage and alveolar tissue dysplasia. Prenatal DEX treatment decreased ADMA and increased iNOS expres- sion. Prenatal DEX treatment also increased TNF-α transcript expression and decreased HDAC2 protein expression at acute stage. In conclusion, repetitive prenatal DEX has prolonged stress damage effects on lung tissue.

关键词： Prenatal glucocorticoids ADMA DNA oxidative damage TNF-α HDAC2 Lung dysplasia

Management of Post-Traumatic Stress (PTSD) Dementia and Other Neuro-Degenerative Disease w.th Photo-Medicine: Clinical Experience and Case Studies

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Open Journal of Psychiatry 2017年第4期7卷 386-394页

作者： w.lliam Stephan Ronald aung Din Louis J. Banas John Thomas Carolyn Kochert Randy J. Lamartiniere Carol Spooner Gerard Pesca Dudley Chew.ing Eddy 4080 Delaw.re Ave Tonawanda New York USA 3501 Cattlemen Drive Sarasota FL USA 3218 Daugherty Ave Suite Lafayette IN USA Photo-Medicine 8676 Goodw.od Boulevard Baton Rouge LA USA Laser Innovations LLC 2451 East Baseline Road Gilbert AZ USA LMFT 820 Jordan St. Suite 570 Shreveport LA USA

Objective: Photobiomodulation (also know. as Low.Level Laser. LLLT or Cold Laser;Photo Medicine (PM)) has been a vital adjunct therapy in our clinical practice over 5 years, observations of improvement in cognition and personality w.re noted in several patients. As a result, selected patients w.th Alzheimer’s Disease, vascular dementia, post-traumatic brain injury and other neuro-degenerative diseases w.re treated at clinical practices in Buffalo, New.York;Sarasota, Florida;Lafayette, Indiana;Phoenix, Az., and Baton Rouge, La. Over 60 patients w.re treated w.th an average of 4 times over an 8-day period all reported/exhibited improvement in their condition, except that tw. men w.o w.re in their seventies w.re in robust health but had no short-term memory and no improvement w.s observed. How.ver, Theralase has developed a more efficacious system w.ich w.ll be more efficacious, due to increased pow.r for ATP activation. Method: Over 150 patients w.th the above conditions w.re treated in various areas (depending on diagnosis) including the prefrontal cortex, temporal lobe, Hippocampus, and Circle of w.llis for duration of tw. and one-half minutes every 48 hours for 5 - 6 treatments. w. utilized the Theralase multi-probe (905 nm/660 nm) at 60 miliw.tts. It utilizes 5 - 905 nm near infra-red diodes and 4 infra-red 660 laser diodes w.th a peak pow.r of 50,000 milliw.tts at peak and pulse duration of 200 nanoseconds [1]. The PTSD patients w.re evaluated utilizing the co-occurring disorders program screening and assessment form. Conclusion: Dementia patients exhibited varying degrees of improvement in cognitive function and personality, leading to improved quality of life and decreased caregiver burden. PTSD patients’ improvement w.s objectively measured by formal neuropsychological testing utilizing the form. All PTSD patients scored no emotional problems after 3 - 5 treatments and all experienced overall sense of w.ll-being. One experienced return of ability to smell he h

关键词： Photobiomodulation Photo Medicine (PM) Neuroregeneration Neuro-Degenerative Disease Small Vessel Disease (SVD)

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稻田主导杀虫剂对稻纵卷叶螟的杀卵作用

应用昆虫学报 2022年第5期59卷 1109-1121页

作者：郭嘉雯何晓婵成义沙 aung Thura 鲁艳辉李文强徐红星黄建雷吴俨吕仲贤农产品质量安全危害因子与风险防控省部共建国家重点实验室浙江省农业科学院植物保护与微生物研究所杭州310021 金华市农业科学研究院金华321000 贵州省山地珍稀动物与经济昆虫重点实验室贵阳学院生物与环境工程学院贵阳550005 河北北方学院张家口075000

【目的】明确稻田主导杀虫剂对稻纵卷叶螟Cnaphalocrocis medinalis的杀卵作用,为科学安全高效防控稻纵卷叶螟提供理论依据。【方法】选用稻田主导的8种杀虫剂(氯虫苯甲酰胺、阿维菌素、毒死蜱、茚虫威、吡虫啉、吡蚜酮、噻虫嗪和噻嗪... 详细信息

【目的】明确稻田主导杀虫剂对稻纵卷叶螟Cnaphalocrocis medinalis的杀卵作用,为科学安全高效防控稻纵卷叶螟提供理论依据。【方法】选用稻田主导的8种杀虫剂(氯虫苯甲酰胺、阿维菌素、毒死蜱、茚虫威、吡虫啉、吡蚜酮、噻虫嗪和噻嗪酮),比较不同杀虫剂对不同日龄卵的毒杀效果及其对初孵幼虫存活和卵后续发育的影响。【结果】选择产后1-4日卵进行处理发现,氯虫苯甲酰胺对卵的校正孵化抑制率在10.42%-100.00%之间,杀卵活性最强。其中,氯虫苯甲酰胺处理1日龄和3日龄卵时毒力较大(LC为2.123和1.904mg/L),处理1日龄卵可导致卵无法正常发育成胚胎,说明其在稻纵卷叶螟卵初产时防治更佳。吡虫啉对卵的校正孵化抑制率在20.00%-91.67%之间,杀卵作用最强。3-4日龄卵经吡虫啉处理后卵孵化受抑制,此时期处理卵对稻纵卷叶螟的杀卵效果最好,初孵幼虫的致死率更高,说明其可在产卵2日后防治。【结论】8种杀虫剂中氯虫苯甲酰胺对稻纵卷叶螟杀卵活性最强,其在卵初产时处理杀卵效果最高,吡虫啉和噻虫嗪对稻纵卷叶螟也具有一定杀卵作用,其中吡虫啉的杀卵作用更强,其更适宜处理产后3-4日龄卵。

关键词：稻纵卷叶螟卵发育杀虫剂毒力浸卵法

Hypnotherapy for overw.ight and obese patients:A narrative review

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Journal of Integrative Medicine 2021年第1期19卷 1-5页

作者： Nurul Afiedia Roslim Aryati Ahmad Mardiana M ansor Myat Moe Thw. aungc Farrahdilla Hamzah Haszalina Hassan Pei Lin Lua Faculty of Pharmacy Universiti Sultan Zainal Abidin(UniSZA)Kampus Besut22200 BesutTerengganuMalaysia Faculty of Health Science Universiti Sultan Zainal Abidin(UniSZA)Kampus Gong Badak21300 Kuala NerusTerengganuMalaysia Faculty of Medicine Universiti Sultan Zainal Abidin(UniSZA)Kampus Kota20400 Kuala TerengganuTerengganuMalaysia

Obesity and overw.ight problems are serious global health issues today and despite many efforts,the prevalence has continued to rise for ***,hypnotherapy has been gaining recognition as an effective treatment for obesity and overw.ight *** review.compiles contemporary scientific research on the effectiveness of hypnotherapy for w.ight ***,Pub Med and EBSCO Host databases w.re applied in the *** search identified 119 articles,of w.ich seven met the inclusion criteria.A total of 539 respondents(82.7%w.men and 17.3%men)betw.en the ages of 17 and 67 years w.re represented in the seven *** studies incorporated lifestyle changes,such as changes of dietary habit and behavioral recommendations in the hypnotic *** results suggested that the use of hypnotherapy not only promoted w.ight reduction during the treatment period but also after treatment cessation,and in some cases,one to ten kilograms w.re lost during follow.up *** addition,one study even show.d increased physical activity among the hypnotised *** use of hypnotherapy also improved respondents'eating behavior and quality of ***,a definitive conclusion could not be draw. due to several methodological flaw. and the limited number of published studies in this ***,further w.ll-designed studies are needed to substantiate the effectiveness of hypnotherapy for this modern-day health problem.

关键词： Hypnotherapy Mind-body interventions Obesity Overw.ight