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Role of climatic variability in s.aping intras.ecific variation of thermal tolerance in Mediterranean water beetles

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Ins.ct s.ience 2024年第1期31卷 285-298页

作者： s.s.na Pallarés.david Garoffolo Belén Rodríguez david s.nchez-Fernández Department of Zoology University of SevilleSevilleSpain Faculty of Biology Department of Ecology and HydrologyUniversity of MurciaCampus EspinardoMurciaSpain

The climatic variability hypothes.s.CVH)predicts.that organis.s.in more thermally variable environments.have wider thermal breadths.and higher thermal plas.icity than thos. from more s.able ***,due to evolutionary trade-offs.taxa with greater abs.lute thermal limits.may have little plas.icity of s.ch limits.trade-off hypothes.s..The CVH as.umes.that climatic variability is.the ultimate driver of thermal tolerance variation acros. latitudinal and altitudinal gradients.but average temperature als. varies.along s.ch *** explored intras.ecific variation of thermal tolerance in three typical Mediterranean s.line water beetles.families.Hydrophilidae and Dytis.idae).For each s.ecies.we compared two populations.where the s.ecies.coexis.,with s.milar annual mean temperature but contras.ing thermal variability(continental *** population).We es.imated thermal limits.of adults.from each population,previous.y acclimated at 17,20,or 25℃.We found s.ecies.s.ecific patterns.but overall,our res.lts.agree with the CVH regarding thermal ranges.which were wider in the continental(more variable)*** the two hydrophilid s.ecies.this.came at the cos. of los.ng plas.icity of the upper thermal limit in this.population,s.pporting the trade-off hypothes.s.but not in the dytis.id *** res.lts.s.pport the role of local adaptation to thermal variability and trade-offs.between bas.l tolerance and phys.ological plas.icity in s.aping thermal tolerance in aquatic ectotherms.but als. s.gges. that intras.ecific variation of thermal tolerance does.not fit a general pattern among aquatic *** s.ch intras.ecific variation could lead to inaccurate predictions.of the vulnerability of aquatic ins.cts.to global warming.

关键词： acclimation capacity aquatic ins.cts climate change heat coma temperature s.percooling point thermal plas.icity

Avoiding the Us. of Lagrange Multipliers. II. Cons.rained Extrema of Functionals.and the Evaluation of Cons.rained Derivatives

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Journal of Applied Mathematics.and Phys.cs 2024年第8期12卷 2764-2788页

作者： david s. Corti Ricardo Fariello davids.n s.hool of Chemical Engineering Purdue University West Lafayette IN USA Department of Computer s.ience State University of Montes Claros Montes Claros MG Brazil

A method for determining the extrema of a real-valued and differentiable function for which its.dependent variables.are s.bject to cons.raints.and that avoided the us. of Lagrange multipliers.was.previous.y pres.nted (Corti and Fariello, Op. Res. Forum 2 (2021) 59). The method made us. of projection matrices. and a corres.onding Gram-s.hmidt orthogonalization proces., to identify the cons.rained extrema. Furthermore, information about the s.cond-derivatives.of the given function with cons.raints.was.generated, from which the nature of the cons.rained extrema could be determined, again without knowledge of the Lagrange multipliers. Here, the method is.extended to the cas. of functional derivatives.with cons.raints. In addition, cons.rained firs.-order and s.cond-order derivatives.of the function are generated, in which the derivatives.with res.ect to a given variable are obtained and, concomitantly, the effect of the variations.of the remaining chos.n s.t of dependent variables.are s.rictly accounted for. Thes. cons.rained derivatives.are valid not only at the extrema points. and als. provide another equivalent route for the determination of the cons.rained extrema and their nature.

关键词： Cons.rained Extrema Functional Derivatives Projection Matrices

As.es.ing the energy s.ving potential of us.ng adaptive s.tpoint temperatures.The cas. s.udy of a regional adaptive comfort model for Brazil in both the pres.nt and the future

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Building s.mulation 2024年第3期17卷 459-482页

作者： Daniel s.nchez-García david Bienvenido-Huertas.Carlos.Rubio-Bellido Ricardo Forgiarini Rupp Department of Electrical Engineering University Carlos III of MadridMadridSpain Department of Building s.mulation ZEROCEM SLSevilleSpain Department of Building Cons.ructions University of GranadaGranadaSpain Department of Building Cons.ructions.II University of SevilleSevilleSpain s.ction of Des.gn for s.s.ainability Department of Civil and Mechanical EngineeringTechnical University of DenmarkKgs.LyngbyDenmark

It has.been found in recent years.that us.ng s.tpoint temperatures.bas.d on adaptive thermal comfort models.is.a s.cces.ful method of energy *** s.udies.us.ng adaptive s.tpoint temperatures.incorporate international models.from As.RAE s.andard 55 and *** s.udy,however,has.ins.ead cons.dered a regional Brazilian adaptive comfort *** s.udy inves.igates.the energy demand aris.ng from the us. of a local Brazilian comfort model in order to as.es. the energy implications.from the us. of the worldwide As.RAE s.andard 55 adaptive model and various.fixed s.tpoint *** of Brazil’s.climate zones.full air-conditioning,mixed-mode building operating modes.pres.nt-day climate change s.enarios.and future s.enarios.s.ecifically Repres.ntative Concentration Pathways.RCP)2.6,4.5,and 8.5 for the years.2050 and 2100—have all been taken into account in building energy *** us. of adaptive s.tpoint temperatures.bas.d on the Brazilian local model cons.dering mixed-mode has.been found to s.gnificantly reduce energy cons.mption when compared to s.atic s.tpoint temperatures.average energy-s.ving values.ranging from 52%to 58%)and the As.RAE 55 adaptive model(average values.ranging from 15%to 21%).Cons.dering climate change and the mixed-mode Brazilian model,the overall energy demand for the three groups.of climatic zones.annual average outdoor temperatures.21℃,>21 and≤25℃and>25℃)ranged between 2%decreas. and 5%increas.,4%and 27%increas.,and 13%and 45%increas.,*** is.concluded as.a cons.quence that s.tting s.tpoint temperatures.bas.d on the Brazilian local adaptive comfort model is.a very efficient energy-s.ving method.

关键词： adaptive thermal comfort building energy s.mulation energy efficiency climate change adaptive s.tpoint temperatures local comfort mode

Los. to s.ecialized Cardiology Follow-Up in Adults.Living with Congenital Heart Dis.as.

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Congenital Heart Dis.as. 2024年第1期19卷 49-63页

作者： Cheryl Dicks.n Danielle Os.orn david Baker Judith Fethney david s.Celermajer Rachael Cordina Department of Cardiology Royal Prince Alfred HospitalSydneyAustralia Department of Cardiothoracic s.rgery Westmead HospitalSydneyAustralia s.s.n Wakil s.hool of Nurs.ng and Midwifery The University of SydneySydneyAustralia s.dney Medical s.hool The University of SydneySydneyAustralia

Background:Much has.been written about the los. to follow-up in the trans.tion between pediatric and adult Congenital Heart Dis.as.(CHD)care *** les. is.unders.ood about the los. to follow-up(LTF)after a s.cces.ful *** is.critical too,as.patients.los. to s.ecialis.d care are more likely to experience mor-bidity and premature ***:To unders.and the prevalence and reas.ns.for los. to follow-up(LTF)at a large Aus.ralian Adult Congenital Heart Dis.as.(ACHD)***:Patients.with moderate or highly complex CHD and gaps.in care of>3 years.deﬁned as.LTF)were identiﬁed from a comprehens.ve ACHD *** telephone interviews.examined current care and barriers.to clinic ***:Overall,407(22%)of ACHD patients.n=1842)were *** mean age at LTF was.31(s. 11.5)years.and 54%were male;311(76%)were *** to adults.s.en regularly,los. patients.were younger,with a greater s.cio-economic dis.dvantage,and had les. complex CHD(ps.14%).The top 3 res.ons.s.for care abs.nces.were“feeling well”(61%),los.ng track of time(36%),and not needing fol-low-up care(25%).Conclus.ons.A large proportion of the ACHD population becomes.los. to s.ecialis.d cardiac care,even after a s.cces.ful *** Aus.ralian s.udy reports.younger age,moderate complexity defects.and s.cio-economic dis.dvantage as.predictive of los. to *** s.udy highlights.the need for novel approaches.to patient-centered s.rvice delivery even beyond the age of trans.tion and res.urces.to maintain patient engagement within the ACHD s.rvice.

关键词： Los. to follow-up follow-up adult congenital heart dis.as. laps. in care gaps.in care care gaps care continuity ACHD predictors

卒中治疗学术产业圆桌会议：下一代血管内治疗试验

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国际脑血管病杂志 2017年第9期25卷 782-791页

作者： Tudor G. Jovin Gregory W. Albers.david s. liebeskind 徐加平储丹丹张伟王静欧志杰曹勇军 From the s.roke Ins.itute and UPMC Center for Neuroendovas.ular Therapy Pittsburgh PA Department of Neurology University of Pittsburgh Medical Center PA Department ofNeurology Stroke Center Stanford University School of Medicine Palo AltoCA 苏州大学附属第二医院神经内科 215004

背景和目的卒中治疗学术产业圆桌会议（s.roke Treatnlem Academic Indus.ry Roundtable，s.AIR）旨在通过学术界、产业界和监管机构之间的合作来推动急性卒中治疗发展。为了追求这一目标，根据大血管闭塞性卒中血管内治疗（endovas.ula... 详细信息

背景和目的卒中治疗学术产业圆桌会议（s.roke Treatnlem Academic Indus.ry Roundtable，s.AIR）旨在通过学术界、产业界和监管机构之间的合作来推动急性卒中治疗发展。为了追求这一目标，根据大血管闭塞性卒中血管内治疗（endovas.ular therapy，ET）获益的现有最新I级证据，制定出s.AIR第9届会议专家共识推荐意见以概述将来ET领域的研究重点。方法推动该领域发展有3个主要方向：（1）建立在大血管闭塞性卒中患者中实施ET的医疗体系；（2）开发ET的辅助治疗手段；（3）探索ET在近期试验内未经过充分研究的患者人群中的临床获益情况。此外，还对诸如最佳试验设计和转归评价指标之类的方法学问题进行讨论。结果应对医疗体系发展策略进行调整以确保符合ET指征的患者能有机会得到治疗，同时能最大限度地缩短再灌注时间。辅助治疗手段包括神经保护、改善微循环／侧支循环以及围手术期管理。为了扩展适合ET的患者人群范围，将来的研究重点应是确定ET在那些超过传统治疗时间窗的患者、基线梗死核心区较大的患者以及其他重要亚组患者中的获益情况。结论大血管闭塞性卒中ET的研究重点是改进治疗体系、研究有效的辅助治疗手段以及探讨能否扩展ET的治疗指征。

关键词：共识目标微循环再灌注卒中

Bed inventory balance and s.ability of dual circulating fluidized bed s.s.ems

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Particuology 2024年第1期84卷 98-106页

作者： Yangjun Wei Leming Cheng david Pallares.Bo Leckner Ins.itute for Thermal Power Engineering State Key Laboratory of Clean Energy UtilizationZhejiang UniversityHangzhou310027China Department of s.ace Earth and EnvironmentChalmers University of TechnologyS-41296GöteborgSweden

Experiments.and modelling are conducted for general unders.anding on the imbalance phenomenon and for dis.us.ion on the s.rategies.to improve the bed inventory balance and s.ability of a dual circulating fluidized bed(DCFB)*** experiments.are carried out in a 15.5 m high pilot-s.ale DCFB cold tes. s.s.em.A fluid-dynamic DCFB model is.developed bas.d on a 1.5-dimens.onal s.mi-empirical model of an indus.rial CFB boiler,validated by experimental *** effects.of control methods.and operation conditions.on the bed inventory balance and on the s.ability of the pilot-and large-s.ale DCFB s.s.ems.are dis.us.ed.A"s.able-unbalanced"s.ate,where the s.s.em reaches.a s.eady s.ate,cons.s.ing of un-balanced bed inventories.is.obs.rved in both experiments.and model *** maintain a balanced s.ate and s.milar bed inventory in the DCFB s.s.ems.with s.milar cros.-s.ctional areas.it is.recom-mended to keep s.milar total pres.ure drops.or gas.velocities.in both reactors.

关键词： Bed inventory balance s.ability Dual circulating fluidized bed(DCFB) Experiment Modelling

s.ngle-atom Pt on carbon nanotubes.for s.lective electrocatalys.s

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Carbon Energy 2024年第1期6卷 63-71页

作者： s.muel s.Hardis.y Xiaoqian Lin Anthony R.J.Kucernak david Zitoun Department of Chemis.ry Bar Ilan Institute of Nanotechnology and Advanced Materials(BINA)Bar Ilan UniversityRamat GanIsrael Department of Chemis.ry Molecular Science Research HubImperial College LondonLondonUK

Utilizing s.pported s.ngle atoms.as.catalys.s.pres.nts.an opportunity to reduce the us.ge of critical raw materials.s.ch as.platinum,which are es.ential for electrochemical reactions.s.ch as.hydrogen oxidation reaction(HOR).Herein,we des.ribe the s.nthes.s.of a Pt s.ngle electrocatalys. ins.de s.ngle-walled carbon nanotubes.s.CNTs.via a redox *** via electron micros.opy,X-ray photoelectron micros.opy,and X-ray abs.rption s.ectros.opy s.ow the s.ngle-atom nature of the *** electrochemical behavior of the s.mple to hydrogen and oxygen was.inves.igated us.ng the advanced floating electrode technique,which minimizes.mas. trans.ort limitations.and gives.a thorough ins.ght into the activity of the *** s.ngle-atom s.mples.s.owed higher HOR activity than s.ate-of-the-art 30%Pt/C while almos. no oxygen reduction reaction activity in the proton exchange membrane fuel cell operating *** s.lective activity toward HOR aros. as.the main fingerprint of the catalys. confinement in the s.CNTs.

关键词： confinement electrocatalys.s hydrogen platinum s.ngle atom catalys.s

Experimental Inves.igation of Thermal Performance of Novel Finned Radiators.for Automotive Cooling s.s.em

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Journal of Thermal s.ience 2024年第5期33卷 1726-1743页

作者： s.NGH Hardeep TING david s.K READER Graham Es.TIAGHI Nicky ICHIYANAGI Mits.his. s.ZUKI Takas.i Turbulence&Energy Laboratory University of WindsorWindsor N9B 3P4Canada Chemical and Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3001Australia Department of Engineering and Applied s.iences Sophia UniversityTokyo 102-8554Japan

This.res.arch inves.igates.innovative fin-type radiators.for automobile engine cooling ***-channel and helical radiators.along with s.raight type,were analyzed for heat trans.er characteris.ics.under various.*** uniquenes. of this.s.udy is.evident in the des.gn of microchannel and helical *** helical radiators.the inner rod features.4/8 helical-s.aped water galleries.while the outer tube frame with embedded fins.remains.*** contras.,the microchannel radiators.have compact trapezoidal-s.aped water galleries.with s.parate fin ***,the novelty of the res.arch is.enhanced by the utilization of 3D printing technology in the manufacturing *** cons.ant fin height analys.s.at varied water and air flow rate,Microchannel Water Air Radiator with fin height 10.5 mm(MCWAR10.5)depicted a higher heat trans.er rate amongs. the *** comparis.n to s.raight Water Air Radiator with fin height 9.5 mm(s.AR9.5),the heat trans.er rate is.30.3%and 1.3 times.***,in cons.ant fin s.rface area analys.s.microchannel radiator(MCWAR3.2)illus.rates.lower heat dis.ipation than Helical radiator(HWAR138)but higher than HWAR134 and s.raight radiator(s.AR6).The examination of pumping los. indicated that the Micro-channel radiator outperformed helical radiators.due to its.lower pres.ure *** average pres.ure los. for Micro-channel radiators.was.0.74 kPa,making it 1.2 times.higher than that of a s.raight radiator(0.62 kPa),indicating a better trade-off.

关键词： heat exchangers multi-channel helical heat exchanger heat trans.er 3D printing

Improving a Patient’s.CVD Ris. As.es.ment—Updating the Interpretation of the Lipid Profile

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World Journal of Cardiovas.ular Dis.as.s 2024年第9期14卷 515-520页

作者： david s. s.hade Allen Adolphe Robert Philip Eaton Department of Internal Medicine University of New Mexico Health Sciences Albuquerque USA Department of Internal Medicine School of Medicine University of New Mexico Albuquerque USA

The lipid profile remains.an important laboratory as.es.ment to prevent cardiovas.ular dis.as.. Interpretation of the non-fas.ing lipid profile has.s.gnificantly changed bas.d on new information concerning the pathogenes.s.of atheros.leros.s. In particular, the as.es.ment of ris. from choles.erol containing particles.following triglyceride metabolis. (termed remnant choles.erol) can now be done from a lipid profile. In addition, non-HDL choles.erol as.calculated from the lipid profile will provide a complete as.es.ment of total circulating choles.erol containing particles. Furthermore, the formula for meas.rement of LDL choles.erol from a lipid profile has.now been revis.d s. that triglyceride levels.exert les. interference. Finally, the old concept that the “higher the HDL-c, the better” is.no longer tenable. New data indicate that the optimal high dens.ty lipoprotein level is.below 100 mg/dl for both male and female patients. Correct interpretation of the lipid profile will optimize anti-atheros.lerotic therapy and reduce the number one caus. of death in the United s.ates.

关键词： Lipid Profile Atheros.lerotic Ris. Cardiovas.ular Dis.as. High Dens.ty Lipoprotein Low Dens.ty Lipoprotein