检索结果-南通市图书馆

Nutritional epigenetics education improves diet and attitude of parents of children with autism or attention deficit/hyperactivity disorder

引用

World Journal of Psychiatry 2024年第1期14卷 159-178页

作者： Renee J Dufault Katherine m Adler david O Carpenter Steven G Gilbert Raquel A Crider College of Graduate Health Studies A.T.Still UniversityKirksvilleMO 63501United States Department of Research Food Ingredient and Health Research InstituteNaalehuHI 96772United States Department of Health Sciences University of New HavenWest HavenCT 06516United States Institute for Health and the Environment School of Public HealthState University of New YorkAlbanyNY 12222United States Department of Research Institute of Neurotoxicology and Neurological DisordersSeattleWA 98105United States Department of Statistics Food Ingredient and Health Research InstituteNaalehuHI 96772United States

BACKGROUND Unhealthy maternal diet leads to heavy metal exposures from the consumption of ultra-processed foods that may impact gene behavior across generations,creating conditions for the neurodevelopmental disorders known as autism and attention deficit/hyperactivity disorder(ADHD).Children with these disorders have difficulty metabolizing and excreting heavy metals from their bloodstream,and the severity of their symptoms correlates with the heavy metal levels measured in their *** may play a key role in helping parents reduce their ultra-processed food and dietary heavy metal intake by providing access to effective nutritional epigenetics *** To test the efficacy of nutritional epigenetics instruction in reducing parental ultra-processed food *** The study utilized a semi-randomized test and control group pretest-posttest pilot study design with participants recruited from parents having a learning-disabled child with autism or ***-two parents who met the inclusion criteria were randomly selected to serve in the test(n=11)or control(n=11)*** test group participated in the six-week online nutritional epigenetics tutorial,while the control group did *** efficacy of the nutritional epigenetics instruction was determined by measuring changes in parent diet and attitude using data derived from an online diet survey administered to the participants during the pre and post intervention *** intake scores were derived for both ultra-processed and whole/organic *** sample t-tests were conducted to determine any differences in mean diet scores within each *** There was a significant difference in the diet scores of the test group between the pre-and post-intervention *** parents in the test group significantly reduced their intake of ultra-processed foods with a preintervention diet score of 70(mean=5.385,SD=2.534)and a post-intervention diet score of 113(mean=8.692,SD=1.750)and the

关键词： Epigenomics Parenteral nutrition Autism Attention deficit/hyperactivity disorder Ultra-processed foods Heavy metals

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhanced Hoek-Brown(H-B)criterion for rocks exposed to chemical corrosion

引用

International Journal of mining Science and Technology 2024年第5期34卷 609-630页

作者： Hao Li Leo Pel Zhenjiang You david Smeulders Department of mechanical Engineering Eindhoven University of TechnologyEindhoven 5600 MBthe Netherlands Department of Applied Physics Eindhoven University of TechnologyEindhoven 5600 MBthe Netherlands Center for Sustainable Energy and Resources School of EngineeringEdith Cowan UniversityJoondalupWA 6027Australia School of Chemical Engineering The University of QueenslandBrisbaneQLD 4072Australia Gas and Energy Transition Research Centre The University of QueenslandBrisbaneQLD 4072Australia

Underground constructions often encounter water environments,where water–rock interaction can increase porosity,thereby weakening engineering ***,the failure criterion for chemically corroded rocks becomes essential in the stability analysis and design of such *** study enhances the applicability of the Hoek-Brown(H-B)criterion for engineering structures operating in chemically corrosive conditions by introducing a kinetic porosity-dependent instantaneous mi(KPIm).A multiscale experimental investigation,including nuclear magnetic resonance(NmR),X-ray diffraction(XRD),scanning electron microscopy(SEm),pH and ion chromatography analysis,and triaxial compression tests,is employed to quantify pore structural changes and their linkage with the strength responses of limestone under coupled chemical-mechanical(C-m)*** employing ion chromatography and NmR analysis,along with incorporating the principles of free-face dissolution theory accounting for both congruent and incongruent dissolution,a kinetic chemical corrosion model is *** model aims to calculate the kinetic porosity alterations within rocks exposed to varying H+concentrations and ***,utilizing the generalized mixture rule(GmR),the kinetic porositydependent mi is *** of the KPIm-enhanced H-B criterion using compression test data from 5 types of rocks demonstrated a high level of consistency between the criterion and the experimental results,with a coefficient of determination greater than 0.96,a mean absolute percentage error less than 4.84%,and a root-mean-square deviation less than 5.95 ***,the physical significance of the porosity-dependent instantaneous mi is clarified:it serves as an indicator of a rock’s capacity to leverage the confining pressure effect.

关键词： Hoek-Brown(H-B)criterion Instantaneous mi Kinetic porosity-dependency Chemical corrosion Compressive strength

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bed inventory balance and stability of dual circulating fluidized bed systems

引用

Particuology 2024年第1期84卷 98-106页

作者： Yangjun Wei Leming Cheng david Pallares Bo Leckner Institute for Thermal Power Engineering State Key Laboratory of Clean Energy UtilizationZhejiang UniversityHangzhou310027China Department of Space Earth and EnvironmentChalmers University of TechnologyS-41296GöteborgSweden

Experiments and modelling are conducted for general understanding on the imbalance phenomenon and for discussion on the strategies to improve the bed inventory balance and stability of a dual circulating fluidized bed(DCFB)*** experiments are carried out in a 15.5 m high pilot-scale DCFB cold test system.A fluid-dynamic DCFB model is developed based on a 1.5-dimensional semi-empirical model of an industrial CFB boiler,validated by experimental *** effects of control methods and operation conditions on the bed inventory balance and on the stability of the pilot-and large-scale DCFB systems are discussed.A"stable-unbalanced"state,where the system reaches a steady state,consisting of un-balanced bed inventories,is observed in both experiments and model *** maintain a balanced state and similar bed inventory in the DCFB systems with similar cross-sectional areas,it is recom-mended to keep similar total pressure drops or gas velocities in both reactors.

关键词： Bed inventory balance Stability Dual circulating fluidized bed(DCFB) Experiment modelling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Balancing machine learning and artificial intelligence in soil science with human perspective and experience

引用

Pedosphere 2024年第1期34卷 9-12页

作者： david C.WEINDORF Somsubhra CHAKRABORTY Department of Earth and Atmospheric Science Central Michigan Universityount Pleasant M148859USA Agricultural and Food Engineering Department Indian Institute of TechnologyKharagpur 721302India

machine learning and artificial intelligence continue to evolve at a rapid pace, with many potential applications related to soil science. Even so, human experience and perception play an invaluable role in characterizing soil properties, especially qualitative properties that may elude sensing/computer-based modeling approaches. The elegant solution to this conundrum relies on the synthesis of computer-aided predictive modeling with human insight and *** global population surpasses 8 billion, the importance of optimized agronomic production to feed a hungry world has never been more important.

关键词： soil elude qualitative

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Utilization of pH-driven methods to fortify nanoemulsions with multiple polyphenols

引用

Food Science and Human Wellness 2024年第4期13卷 1943-1950页

作者： Hualu Zhou Bingjing Zheng david Julian mcClements Department of Food Science and Technology College of Agricultural and Environmental SciencesUniversity of GeorgiaGriffinGA 30223USA Biopolymers and Colloids Laboratory Department of Food ScienceUniversity of MassachusettsAmherstMA 01003USA Department of Food Science&Bioengineering Zhejiang Gongshang UniversityHangzhou 310018China

Simple but effective methods are required to incorporate multiple bioactive polyphenols into delivery systems to increase their dispersibility,stability and *** developed and tested three p Hdriven protocols for creating nanoemulsions loaded with multiple lipophilic *** protocols differed in how the different polyphenols were incorporated into the *** impact of these three methods on the formation,properties,and gastrointestinal fate of nanoemulsions loaded with curcumin,resveratrol,and quercetin was *** three methods produced nanoemulsions with similar initial particle properties:droplet diameters(0.15,0.16,and 0.15μm)and zeta-potentials(–59,–58,and–58 m V),***,the average encapsulation efficiencies(82%,88%,and 61%),gastrointestinal stabilities(83%,97%,and 29%)and bioaccessibilities(77%,90%,and 73%)for curcumin,resveratrol,and quercetin were somewhat *** particular,more quercetin degradation occurred using the approach that held it under alkaline conditions for extended *** general,the p H-driven method provides researchers with a versatile approach of incorporating multiple polyphenols with different characteristics into functional food and beverages using a simple and inexpensive method.

关键词： Polyphenols pH-Driven encapsulation Nanoemulsions Gastrointestinal fate Functional foods

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Extreme Antarctic Cold of Late Winter 2023

引用

Advances in Atmospheric Sciences 2024年第10期41卷 1873-1880页

作者： Anastasia J.TOmANEK david E.mIKOLAJCZYK matthew A.LAZZARA Stefano DI BATTISTA minghu DING mariana FONTOLAN LITELL david H.BROmWICH Taylor P.NORTON Linda m.KELLER Lee J.WELHOUSE Antarctic meteorological Research and Data Center Space Science and Engineering CenterUniversity of Wisconsin-MadisonMadisonWisconsin 53706USA Department of Physical Sciences School of EngineeringScienceand MathematicsMadison Area Technical CollegeMadisonWisconsin 53704USA meteogiornale via Paolo Diacono9Milano 20133Italy State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Byrd Polar and Climate Research Center The Ohio State UniversityColumbusOhio 43210USA Department of Geography The Ohio State UniversityColumbusOhio 43210USA

Extreme cold temperatures were observed in July and August 2023,coinciding with the WINFLY(winter fly-in)period of mid to late August into September 2023,meaning aircraft operations into mcmurdo Station and Phoenix Airfield were adversely ***,with temperatures below−50℃,safe flight operation was not possible because of the risk of failing hydraulics and fuel turning to gel onboard the *** cold temperatures were measured across a broad area of the Antarctic,from East Antarctica toward the Ross Ice Shelf,and stretching across West Antarctica to the Antarctic Peninsula.A review of automatic weather station measurements and staffed station observations revealed a series of sites recording new record low *** separate cold phases were identified,each a few days in duration and occurring from mid-July to the end of August 2023.A brief analysis of 500-hPa geopotential height anomalies shows how the mid-tropospheric atmospheric environment evolves in relation to these extreme cold *** monthly 500-hPa geopotential height anomalies show strong negative anomalies in *** of composite geopotential height anomalies during each of the four cold phases suggests various factors leading to cold temperatures,including both southerly off-content flow and calm atmospheric *** the atmospheric environment that leads to such extreme cold temperatures can improve prediction of such events and benefit Antarctic operations and the study of Antarctic meteorology and climatology.

关键词： Antarctica extreme cold temperature automatic weather station networks

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrated Single-cell multiomic Analysis of HIV Latency Reversal Reveals Novel Regulators of Viral Reactivation

引用

Genomics, Proteomics & Bioinformatics 2024年第1期22卷 67-88页

作者： manickam Ashokkumar Wenwen mei Jackson J.Peterson Yuriko Harigaya david m.murdoch david m.margolis Caleb Kornfein Alex Oesterling Zhicheng Guo Cynthia D.Rudin Yuchao Jiang Edward P.Browne Department of medicine University of North Carolina at Chapel HillChapel HillNC 27599USA HIV Cure Center University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Biostatistics University of North Carolina at Chapel HillChapel HillNC 27599USA Department of microbiology and Immunology University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Genetics University of North Carolina at Chapel HillChapel HillNC 27599USA Department of medicine Duke UniversityDurhamNC 27708USA Department of Computer Science Duke UniversityDurhamNC 27708USA Department of Statistics Texas A&M UniversityCollege StationTX 77843USA Department of Biology Texas A&M UniversityCollege StationTX 77843USA Department of Biomedical Engineering Texas A&M UniversityCollege StationTX 77843USA

Despite the success of antiretroviral therapy,human immunodeficiency virus(HIV)cannot be cured because of a reservoir of latently infected cells that evades *** understand the mechanisms of HIV latency,we employed an integrated single-cell RNA sequencing(scRNA-seq)and single-cell assay for transposase-accessible chromatin with sequencing(scATAC-seq)approach to simultaneously profile the transcriptomic and epigenomic characteristics of~125,000 latently infected primary CD4^(+)T cells after reactivation using three different latency reversing *** expressed genes and differentially accessible motifs were used to examine transcriptional pathways and transcription factor(TF)activities across the cell *** identified cellular transcripts and TFs whose expression/activity was correlated with viral reactivation and demonstrated that a machine learning model trained on these data was 75%-79%accurate at predicting viral ***,we validated the role of two candidate HIV-regulating factors,FOXP1 and GATA3,in viral *** data demonstrate the power of integrated multimodal single-cell analysis to uncover novel relationships between host cell factors and HIV latency.

关键词： HIV latency reversal Primary CD4þT cell Single-cell multiomics HIV-regulating factor machine learning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

There is more to the knee joint than just the quadriceps:A systematic review with meta-analysis and evidence gap map of hamstring strength,flexibility,and morphology in individuals with gradual-onset knee disorders

引用

Journal of Sport and Health Science 2024年第4期13卷 521-536页

作者： Helder S.Lopes marina C.Waiteman Liliam B.Priore Neal R.Glaviano david m.Bazett-Jones Ronaldo V.Briani Fabio m.Azevedo School of Science and Technology Physical Therapy DepartmentSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Department of Kinesiology College of AgricultureHealth and Natural ResourcesUniversity of ConnecticutStorrsCT 06269USA School of Exercise and Rehabilitation Sciences College of Health and Human ServicesUniversity of ToledoToledoOH 43606USA

Background:Impairments in hamstring strength,flexibility,and morphology have been associated with altered knee biomechanics,pain,and *** the presence of these impairments in individuals with gradual-onset knee disorders is important and may indicate targets for assessment and *** systematic review aimed to synthesize the literature to determine the presence of impairments in hamstring strength,flexibility,and morphology in individuals with gradual-onset knee ***:Five databases(mEDLINE,Embase,CINAHL,SPORTDiscus,and Web of Science)were searched from inception to September *** studies comparing hamstring outcomes(e.g.,strength,flexibility,and/or morphology)between individuals with gradual-onset knee disorders and their unaffected limbs or pain-free controls were ***-analyses for each knee disorder were ***-level certainty was assessed using the Grading of Recommendations Assessment,Development,and Evaluation,and evidence gap maps were ***:Seventy-nine studies across 4 different gradual-onset knee disorders(i.e.,knee osteoarthritis(OA),patellofemoral pain(PFP),chondromalacia patellae,and patellar tendinopathy)were *** with knee OA presented with reduced hamstring strength compared to pain-free controls during isometric(standard mean difference(SmD)=-0.76,95%confidence interval(95%CI):-1.32 to-0.21)and concentric contractions(SmD=-0.97,95%CI:-1.49 to-0.45).Individuals with PFP presented with reduced hamstring strength compared to painfree controls during isometric(SmD=-0.48,95%CI:-0.82 to-0.14),concentric(SmD=-1.07,95%CI:-2.08 to-0.06),and eccentric contractions(SmD=-0.59,95%CI:-0.97 to-0.21).No differences were observed in individuals with patellar *** with PFP presented with reduced hamstring flexibility when compared to pain-free controls(SmD=-0.76,95%CI:-1.15 to-0.36).Evidence gap maps identified insufficient evidence for chondromalacia patel

关键词： Chondromalacia patellae Knee flexors Knee osteoarthritis Patellar tendinopathy Patellofemoral pain

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Targeting muscle to treat Charcot-marie-Tooth disease

引用

Neural Regeneration Research 2024年第8期19卷 1653-1654页

作者： david Villarroel-Campos James N.Sleigh Department of Neuromuscular Diseases and UCL Queen Square motor Neuron Disease Centre UCL Queen Square Institute of NeurologyUniversity College LondonLondonUK UK Dementia Research Institute University College LondonLondonUK

Charcot-marie-Tooth disease(CmT)is a hereditary peripheral neuropathy causing muscle weakness/wasting and sensory dysfunction predominantly in limb *** patients display gait abnormalities,foot deformities,loss of sens... 详细信息

关键词： marie sensation neuropathy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Storylines of family medicine Ⅺ:professional identity formation—nurturing one’s own story

引用

Family medicine and Community Health 2024年第S3期12卷 99-108页

作者： William B Ventres Leslie A Stone Hamish J Wilson Sumi m Sexton david J Doukas Jessica P Cerdena david m Kelley michael D Fetters Jeffrey J Haney John J Frey III Family and Preventive medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA General Practice and Rural Health University of Otago Dunedin School of MedicineDunedinNew Zealand Family medicine Georgetown University School of MedicineWashingtonDistrict of ColumbiaUSA Family and Community medicine Tulane University School of MedicineNew OrleansLouisianaUSA Family medicine Residency Program Middlesex HealthMiddletownConnecticutUSA Family medicine University of Michigan Medical SchoolAnn ArborMichiganUSA medical Education and Clinical Sciences Washington State UniversitySpokaneWashingtonUSA Family medicine and Community Health University of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA

Storylines of Family medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅺ:professional identity formation—nurturing one’s own story’,authors address the following themes:‘The social construction of professional identity’,‘On becoming a family physician’,‘What’s on the test?—professionalism for family physicians’,‘The ugly doc-ling’,‘Teachers—the essence of who we are’,‘Family medicine research—it starts in the clinic’,‘Socially accountability in medical education’,‘Personal philosophy and how to find it’and‘Teaching and learning with Storylines of Family medicine’.may these essays encourage readers to find their own creative spark in medicine.

关键词： own becoming professional

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：