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美国医学会杂志（中文版） 2006年第5期25卷 259-265页

作者： Anvar Babaev Paul D. Frederick david j. pasta Nathan Every Tina Sichrovsky j.dith S. Hochman, MD 武蓓（译）陈红（校） Cardiovascular Clinical Research Center New York University School of Medicine New York NY Ovation Research Group Seattle Wash Ovation Research Group and University of California San Francisco Department of Cardiology School of Medicine University of Washington Seattle Division of Cardiology St Luke＇s-Roosevelt Medical Center New York NY 不详

背景：早期机械性血管重建是降低合并心源性休克的急性心肌梗死患者死亡率的一种治疗措施。从1999年起美国心脏病学会（ACC）和美国心脏协会（AHA）制定的指南即将其作为年龄〈75岁患者的Ⅰ类推荐。但是，人们对实践工作中指南的执行情... 详细信息

背景：早期机械性血管重建是降低合并心源性休克的急性心肌梗死患者死亡率的一种治疗措施。从1999年起美国心脏病学会（ACC）和美国心脏协会（AHA）制定的指南即将其作为年龄〈75岁患者的Ⅰ类推荐。但是，人们对实践工作中指南的执行情况知之甚少。目的：评价合并心源性休克的急性心肌梗死患者实施早期血管重建的趋势和死亡率，以便了解国家指南是否对血管重建率产生影响。设计、地点及病例：前瞻性观察研究，共入选293633例ST段抬高的心肌梗死患者（25311例[8．6％]合并心源性休克，其中7536[29％]入院时已有心源性休克）。研究对象来自1995年1月至2004年5月的国家心肌梗死注册登记（National Registry of Myocardial Infarction，NRMI），共有775家具备血管重建能力（定义为能实施心脏导管、经皮冠状动脉介入术[percutaneous caronary intervention，PCI]和心脏直视手术）的美国医院参加。主要观测指标：治疗模式和住院死亡率。结果：在有血管重建能力的医院，直接PCI率从27．4％上升到54．7％（P〈0．001），这与ST段抬高急性心肌梗死中使用PCI比率的变化平行。急性冠状动脉旁路移植手术率变化不大（从2．1％到3．2％）。倾向校正后多变量分析显示，直接PCI与住院期间死亡率的下降有关（OR，0．46；95％可信区间，0．40-0．53）。指南公布后所有年龄段患者血管重建率无明显变化。心源性休克院内总死亡率从1995年的60．3％下降到2004年的47．9％（P〈0．001）。结论：在有血管重建能力的医院，心源性休克患者接受PCI可改善生存情况。ACC葙AHA指南对血管重建率未产生明显影响，提示应加大指南的宣传和执行力度。

关键词：急性心肌梗死心源性休克休克患者治疗心肌梗死患者经皮冠状动脉介入术直接PCI 冠状动脉旁路移植

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TREATMENT OF ADVANCE GLAUCOMAS USING LEKSELL GAMMA KNIFE

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国际眼科杂志 2003年第1期3卷 14-15页

作者： j.Pilbauer j.pasta R.Liscak V.Vladyka Prague Millitary Hospital Prague Millitary HospitalNemocnice Na Homolce Nemocnice na Homolce Czech RepublicNemocnice Na Homolce Nemocnice na Homolce Czech Republic

The use radiosurgery in treatment of glaucomas is a completely new waz of treating stages of this treacherous disease, up to now, the most common indications for the LGK therapy in ophtalmol-ogy at our department are maligmant melanoma,vascular dis-eases,intarocular and intraorbital metastasis,and glioma of the optic *** study shows that focal irradiation of otherwise inevitable enucleation of the eye.

关键词：晚期青光眼勒克塞尔伽玛刀治疗放射外科手术

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等值区域图是真正的地图吗？

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武测译文 1991年第3期 5-8页

作者： pasta.,j.罗丁

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急性心肌梗死伴心源性休克患者的治疗和预后发展趋势

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世界核心医学期刊文摘(心脏病学分册) 2006年第3期 20-21页

作者： Babaev A. Frederick P. D. pasta D. j. j. S. Hochman 王亭忠 Cardiovascular Clinical Research Center NYU School of Medicine HCC 1173 530 First Ave New York NY 10016 United States Dr.

Context: Early mechanical revascularization in patients with acute myocardial infarction(AMI) complicated by cardiogenic shock is a therapeutic strategy that reduces mortality. It has been a class I recommendation in guidelines from the American College of Cardiology and the American Heart Association since 1999 for patients younger than 75 years. However, little is known about implementation of these guidelines in practice. Obj.ctives: To assess trends in early revascularization and mortality for patients with cardiogenic shock complicating AMI and to determine whether the national guidelines affect revascularization rates. Design, Setting, and Patients: Prospective, observational study of 293 633 patients with ST-elevation myocardial infarction(25 311 8.6% had cardiogenic shock; 7356 29% had cardiogenic shock at hospital presentation) enrolled in the National Registry of Myocardial Infarction(NRMI) from j.nuary 1995 to May 2004 at 775 US hospitals with revascularization capability(defined as the capability to perform cardiac catheterization, percutaneous coronary intervention PCI , and open-heart surgery). Main Outcome Measures: Management patterns and in-hospital mortality rates. Results: There was an increase in primary PCI rates from 27.4% to 54.4% (Pj.sted multivariable analyses demonstrated that primary PCI was associated with a decreased odds of death during hospitalization(odds ratio, 0.46; 95% confidence interval, 0.40-0.53). There were no differences in the rates of change in revascularization rates based on the date when the guidelines were released regardless of patient age. Overall in-hospital cardiogenic shock mortality decreased from 60.3% in 1995 to 47.9% in 2004(P< .001). Conclusions: The use of PCI

关键词：心源性休克死亡率血运重建心肌梗死患者

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促甲状腺激素水平与体外受精孕妇妊娠结局的关系

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世界核心医学期刊文摘（妇产科学分册） 2006年第11期2卷 6-7页

作者： Baker V.L. Rone H.M. pasta D.j. 朱磊 Fertility Physicians of Northern California San Jose and Palo Alto CA United States Dr.

Obj.ctive: The aim of this study was to determine if pregnancy outcome for women undergoing in vitro fertilization is correlated with pre-conception thyroid-stimulating hormone level. Study design: We performed a retrospective cohort study of in vitro fertilization cycles in our private practice with an initial positive serum human chorionic gonadotropin level and thyroid-stimulating hormone level available (n = 364). We examined whether or not birth outcome differed between cycles in which the thyroid-stimulating hormone was > 2.5 mIU/L compared with cycles with a thyroid-stimulating hormone level of ≤ 2.5 mIU/L. Logistic regression was used to determine the association between thyroid-stimulating hormone level and spontaneous abortion rate. Results: Delivery outcome was available for 195 cycles, 36% of which had a thyroid-stimulating hormone level > 2.5. The gestational age at delivery was higher in cycles with a thyroid-stimulating hormone ≤ 2.5 than for cycles with a thyroid-stimulating hormone > 2.5 (38.5 vs 38.0 weeks for singletons, 36.0 vs 34.6 weeks for twins, overall P = .012 for thyroid-stimulating hormone level). The mean birth weight for cycles with a thyroid-stimulating hormone ≤ 2.5 was higher than for cycles with a thyroid-stimulating hormone > 2.5 (7.33 vs 6.78 lbs for singletons, P = .024 and 5.36 vs 4.83 lbs for twins, P = .023). Restricting analysis to cycles where the woman was not taking thyroid replacement did not change the overall conclusions. There was a trend toward increasing risk of miscarriage with increasing thyroid-stimulating hormone level in nondonor cycles, controlling for age and day 3 follicle-stimulating hormone level, but this trend did not reach statistical significance. Conclusion: A pre-conce-ption thyroid-stimulating hormone level > 2.5 mIU/L is associated with a lower gestational age at delivery and lower birth weight in women undergoing in vitro fertilization.

关键词：体外受精妊娠结局甲状腺激素水平自然流产率卵泡刺激素促甲状激素胎孕分娩结局回顾性队列研

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Genetic Diversity of Glutenins-Wheat Storage Proteins

Genetic Diversity of Glutenins-Wheat Storage Proteins

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小麦遗传育种国际学术讨论会

作者： L.j.Vapa D.Obreht Institute of Biology Faculty of Sciences21000 Novi SadYugoslavia Institute of Biology Faculty of Sciences21000 Novi SadYugoslavia

＜正＞In the last 30 years extensive research in the biochemistry, genetic and molecular biology of wheatstorage proteins has been carried out to discover their diversity, i.e. allelic variation. The main groups of wheat stor-age proteins are glutenins and gliadins,which account for up to about 60% of the total proteins. These proteinsplay a key role in food processing of bread biscuits and pasta *** are important determinants of BMQ（bread making quality）components in bread wheats conferring visco elastic properties to dough. The recent applica-tion of recombinant DNA technology to wheat endosperm proteins hsa provided a new dimension to understandingstructure and evoutionary relationships of glutenins as the molecular basis of BMQ. A summary of research on ge-netic diversity and molecular biology of storage proteins,glutenins, in the 20 century will presented .

关键词： Allelic variability Electrophoresis Glutenins Wheat

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Hungaro Durum Rye—Breeding, Genome Composition and Amino Acid Content of the First Triticale Cultivar for Human Consumption

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j.urnal of Agricultural Science and Technology(B) 2019年第1期9卷 31-37页

作者： j.zsef Kruppa j.. Klaudia Kruppa j.zsef Kruppa Kruppa-Mag Research Seed Producer and Distributor Ltd. Kisvárda 4600 Hungary Department of Plant Genetic Resources Agricultural Institute Centre for Agricultural Research Hungarian Academy of Sciences Martonvásár 2462 Hungary

Hungaro triticale cultivar was bred for human consumption and animal fodder in Kisvárda, Hungary. The breeding method applied for the recombinant secondary hexaploid triticale proved to be effective since the favourable traits of wheat, durum wheat and rye were successfully combined in the genome of the new cultivar. The first aim was to characterize the genome composition. Multicolour genomic in situ hybridization (mcGISH) was used for the genome compositional analysis. According to the results, the cultivar contains the wheat AB genome (AABB = 28 chromosomes) and the whole rye (R) genome (RR = 14 chromosomes). The presence of D genome, however, could not be detected within the detection limit of the GISH method. Hungaro is the very first triticale in Hungary that has been used for human consumption (milling industry, baking industry, pasta production). In this study, amino acid content of flours was measured. Amino acid investigations on Hungaro durum rye’s flour showed that the quantity of essential amino acids, especially of methionine and cysteine, are higher in Hungaro durum rye than in the also investigated Ryefood rye cultivar and the GK ?thalom wheat cultivar. The genes inherited from the wheat species ensure high yield and great baking and dough making qualities. Therefore, its flour is suitable in itself for pastry and dough production (without mixing it with other flours). Its characteristics inherited from rye guarantee excellent abiotic and biotic resistance.

关键词： Triticale for human consumption Hungaro durum rye quality, GISH.

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