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Intra-procedural arrhythmia during cardiac catheterization: A systematic review of literature

World journal of Cardiology 2020年第6期12卷 269-284页

作者： Fatima A Shaik david j slotwiner Gregory M Gustafson Xuming Dai Division of Cardiology New York Presbyterian Queens HospitalFlushingNY 11355United States

BACKGROUND Cardiac catheterization is among the most performed medical procedures in the modern *** were sporadic reports indicating that cardiac arrhythmias are common during cardiac catheterization,and there are risks of developing serious and potentially life-threatening arrhythmias,such as sustained ventricular tachycardia(VT),ventricular fibrillation(VF)and high-grade conduction disturbances such as complete heart block(CHB),requiring immediate ***,there is lack of systematic overview of these *** To systematically review existing literature and gain better understanding of the incidence of cardiac arrhythmias during cardiac catheterization,and their impact on outcomes,as well as potential approaches to minimize this *** We applied a combination of terms potentially used in reports describing various cardiac arrhythmias during common cardiac catheterization procedures to systematically search PubMed,EMBASE and Cochrane databases,as well as references of full-length *** During right heart catheterization(RHC),the incidence of atrial arrhythmias(premature atrial complexes,atrial fibrillation and flutter)was low(<1%);these arrhythmias were usually transient and *** associated with the development of a new RBBB at a rate of 0.1%-0.3%in individuals with normal conduction system but up to 6.3%in individuals with pre-existing left bundle branch *** patients may require temporary pacing due to transient *** premature ventricular complexes or non-sustained VT are common during RHC(up to 20%of cases).Sustained ventricular arrhythmias(VT and/or VF)requiring either withdrawal of catheter or cardioversion occurred infrequently(1%-1.3%).During left heart catheterizations(LHC),the incidence of ventricular arrhythmias has declined significantly over the last few decades,from 1.1%historically to 0.1%*** overall reported rate of VT/VF in diagnostic LHC and coronary angiography is 0.8

关键词： Catheterization Coronary angiography Percutaneous coronary intervention Ventricular fibrillation Ventricular tachycardia

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex david j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Natural products and drug discovery

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National Science Review 2022年第11期9卷 37-57页

作者： david j.Newman NIH Special Volunteer

This review covers the recent history of a series of very important natural products and their derivatives that are currently in use or under evaluation in the areas of anti-infectives, important cancer treatments that include antibody drug conjugates, followed by a discussion of type 2 diabetes(T2DM) drugs and angiotensin converting enzyme inhibitors. The current structures of the agents are shown, though in the case of some peptides used in T2DM drugs the standard single leTher abbreviation for an amino acid is used.

关键词： artemisinin glycopeptides anthracyclines dolastatin diabetes 2 ACE inhibitors

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Analysis of ancient mass extinction recoveries in marine environments: generating strategies for managing outcomes of the current mass extinction

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National Science Review 2024年第1期11卷 8-10页

作者： david j.Bottjer Department of Earth Sciences University of Southern California

The defining feature of a mass extinction and its associated recovery is the global amount of extinction that occurred[1]. However, there is finer-scale detail to the story, as seen in the ongoing modern mass extinction(the sixth mass extinction), which exhibits variable effects among marine ecosystems and environments, and hence geographic areas [1].

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Positron emission particle tracking——Application and labelling techniques

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Particuology 2008年第1期6卷 16-23页

作者： david j. Parker School of Physics and Astronomy the University of Birmingham Edgbaston Birmingham B15 2TT UK

The positron emission particle tracking （PEPT） technique has been widely used in science and engineering to obtain detailed information on the motion and flow fields of fluids or granular materials in multiphase systems, for example, fluids in rock cracks, chemical reactors and food processors; dynamic behaviour of granular materials in chemical reactors, granulators, mixers, dryers, rotating kilns and ball mills. The information obtained by the PEPT technique can be used to optimise the design, operational conditions for a wide range of industrial process systems, and to evaluate modelling work. The technique is based on tracking radioactively labelled particles （up to three particles） by detecting the pairs of backto-back 511 keV γ-rays arising from annihilation of emitted positrons. It therefore involves a positron camera, location algorithms for calculating the tracer location and speed, and tracer labelling techniques. This paper will review the particle tracking technique from tracking algorithm, tracer labelling to their application.

关键词： PEPT Tracer Algorithm Tracking

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Vlendelian randomization： loosening the Gordian knot of testosterone and male ageing

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Asian journal of Andrology 2013年第5期15卷 579-581页

作者： david j Handelsman ANZAC Research Institute University of SydneySydney NSW 2139 Australia

It is unknown whether the reduced blood testosterone among unselected older men （＂andropause＂） compared to healthy younger men is due to ageing per se or as a non-specific adaptive reaction to chronic diseases acc... 详细信息

关键词： Mendelian randomization loosening male ageing

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Pico-washing:simultaneous liquid addition and removal for continuous-flow washing of microdroplets

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Microsystems & Nanoengineering 2022年第2期8卷 249-261页

作者： Michael j.Siedlik david Issadore Department of Bioengineering University of PennsylvaniaPhiladelphiaPA 19104United States

Droplet microfluidics is based on a toolbox of several established unit operations,including droplet generation,incubation,mixing,pico-injection,and *** the last two decades,the development of droplet microfluidic systems,which incorporate these multiple unit operations into a workflow,has demonstrated unique capabilities in fields ranging from single-cell transcriptomic analyses to materials *** unit operation that is sorely underdeveloped in droplet microfluidics is washing,exchange of the fluid in a droplet with a different ***,we demonstrate what we name the"pico-washer,"a unit operation capable of simultaneously adding fluid to and removing fluid from droplets in flow while requiring only a small footprint on a microfluidic *** describe the fabrication strategy,device architecture,and process parameters required for stable operation of this technology,which is capable of operating with kHz droplet ***,we provide an image processing workflow to characterize the washing process with microsecond and micrometer ***,we demonstrate the potential for integrated droplet workflows by arranging two of these unit operations in series with a droplet generator,describe a design rule for stable operation of the pico-washer when integrated into a system,and validate this design rule *** anticipate that this technology will contribute to continued development of the droplet microfluidics toolbox and the realization of novel droplet-based,multistep biological and chemical assays.

关键词： operations simultaneous removing

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Forest visualization at multiple scales for management and planning

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Science China(Technological Sciences) 2006年第Z1期49卷 27-34页

作者： david j.Mladenoff Department of Forest Ecology and Management

In this study forests were visualized at various scales by placing individual trees into a forest with realistic sizes and densities. Tree images were used from two sources: high quality field photos and images created using graphic design software. The terrain, species composition, and tree sizes and density from forest inventory were all represented in GIS data format. In addition, non-tree objects and features that are essential for close-to-reality visualization were combined with the tree images in a 3-D visualization software package. We further portrayed stand level effects by animating a simulated fly-through of a forest. To visualize temporal change, a case study of four different forest patches was animated. The advantages of this approach comparing to other visualization approaches are: (1) it represents the forests with realistic individual tree images; and (2) it maintains both visual and informational realism in a forest viewable from within-stand to landscape scales. Thus, this approach is realistic in two aspects. First, it is almost as realistic as a photograph, and secondly, its information content is actual forest composition, density, and height.

关键词： 3-D, visualization, forest, landscape, multiple scales.

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A Model System of Development Regulated by the Long-distance Transport of mRNA

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journal of Integrative Plant Biology 2010年第1期52卷 40-52页

作者： david j. Hannapel Plant Biology Major 253 Horticulture Hall Iowa State University

BELl-like transcription factors are ubiquitous in plants and interact with KNOTTEDI-types to regulate numerous developmental processes. In potato, the RNA of several BELl-like transcription factors has been identified in phloem cells. One of these, StBEL5, and its Knox protein partner regulate tuber formation by targeting genes that control growth. RNA detection methods and grafting experiments demonstrated that StBEL5 transcripts move across a graft union to localize in stolon tips, the site of tuber induction. This movement of RNA originates in source leaf veins and petioles and is induced by a short-day photoperiod, regulated by the untranslated regions, and correlated with enhanced tuber production. Addition of the StBEL5 untranslated regions to another *** mRNA resulted in its preferential transport to stolon tips leading to increased tuber production. Upon fusion of the untranslated regions of StBEL5 to a β-glucuronidase marker, translation in tobacco protoplasts was repressed by those constructs containing the 3＇ untranslated sequence. The untranslated regions of the StBEL5 mRNA are involved in mediating its long-distance transport and in controlling translation. The 3＇ untranslated sequence contains an abundance of conserved motifs that may serve as binding motifs for RNA-binding proteins. Because of their presence in the phloem sieve tube system, their unique untranslated region sequences and their diverse RNA accumulation patterns, the family of BEL1-like RNAs from potato represents a valuable model for studying the long-distance transport of full-length mRNAs and their role in development.

关键词： BEL A Model System of Development Regulated by the Long-distance Transport of mRNA Long

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Taxonomic and phylogenetic composition show biotic resistance to exotic invasion in acid seep springs

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Ecological Processes 2021年第1期10卷 77-88页

作者： david F.Barfknecht david j.Gibson School of Biological Sciences Southern Illinois University–CarbondaleCarbondaleIL 62901-6509USA

Background:Few studies have incorporated the evolutionary insights provided by analysis of phylogenetic structure along with community composition to assess the effects of exotic invasion on freshwater ***,we assess the taxonomic and phylogenetic relationships among acid seep springs to investigate the potential homogenization or resistance of communities due to invasion of an exotic ***:Multivariate community analyses indicated differences in community and phylogenetic composition and dispersion among acid seep springs,associated with gradients in soil moisture,canopy cover,and phylogenetic *** contrast,univariate analyses showed differences in taxonomic diversity but not phylogenetic diversity among acid seep ***:Despite exotic invasion,individual acid seep springs remained taxonomically and phylogenetically distinct from each *** and phylogenetic diversity metrics revealed different aspects of composition,reinforcing the importance of including both in analyses of plant communities for understanding community assembly following exotic invasion and for management *** acid seep springs,taxonomic and phylogenetic composition appear to be driven more through environmental filtering by light and moisture than by the competitive effects following invasion of an exotic grass in support of Elton’s biotic resistance hypothesis.

关键词： Acid seep springs Diversity Community Phylogenetics Exotic invasion Environmental filtering NMDS UniFrac Vector analysis

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