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微粒对多晶冰及冰川流变行为的影响——(Ⅰ)基于位错的弛豫模型

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地球物理学报 2007年第1期50卷 126-130页

作者：宋旼 david M.Cole Ian Baker 中南大学粉末冶金国家重点实验室 US Army Cold Regions Research and Engineering Laboratory Hanover NH03755U.S.A. Thayer School of Engineering Dartmouth CollegeHanover NH03755U.S.A.

为量化冰及冰川在流变过程中位错密度随流变应力的变化,发展了一个基于位错的非线性弛豫模型.模型的计算表明:在冰的指数蠕变阶段,滞弹性试验所形成的应力/应变滞后环的宽度与面积随流变应力的增加呈线性增加,位错密度随流变应力的增加... 详细信息

为量化冰及冰川在流变过程中位错密度随流变应力的变化,发展了一个基于位错的非线性弛豫模型.模型的计算表明:在冰的指数蠕变阶段,滞弹性试验所形成的应力/应变滞后环的宽度与面积随流变应力的增加呈线性增加,位错密度随流变应力的增加呈平方增加;在冰的线性蠕变阶段,滞弹性试验所形成的应力/应变滞后环的宽度、面积和位错密度保持不变.

关键词：冰与冰川位错弛豫流变非线性模型

EXPERIMENTAL STUDY ON BED RESISTANCE CHARACTERISTICS OF NONUNIFORM SEDIMENT

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Journal of Hydrodynamics 2000年第4期12卷 66-74页

作者： Zhou, g.D. Liu, Q.Y. Wang, g.X. Hui, Y.J. Pang, D.M. Tsinghua Univ. Beijing 100084 China

Under natural circumstances, the bed of fluvial river is composed of nonuniform sediment, and its nonuniform property influences very much the bed resistance and flow characteristics. By using a one-dimensional laser velocimeter, flume experiments are carried out to analyze the resistance characteristics of open channel flow with the bed sediment composed of different representative particles and having different nonuniform properties. By means of separating factors, the factors affecting the bed resistance, including particle diameter, nonuniform property and flow conditions, are studied. A great number of laboratory test results and field data from other investigators have been analyzed.

关键词： Sediments

Interplay between metabolic dysfunction-associated fatty liver disease and chronic kidney disease:Epidemiology,pathophysiologic mechanisms,and treatment considerations

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World Journal of gastroenterology 2022年第39期28卷 5691-5706页

作者： Panagiotis Theofilis Aikaterini Vordoni Rigas g Kalaitzidis Center for Nephrology“g.Papadakis ”General Hospital of Nikaia-Piraeus“Agios Panteleimon”Nikaia 18454Greece

The recently proposed nomenclature change from non-alcoholic fatty liver disease to metabolic dysfunction-associated fatty liver disease(MAFLD)has resulted in the reappraisal of epidemiological trends and associations with other chronic *** this context,MAFLD appears to be tightly linked to incident chronic kidney disease(CKD).This association may be attributed to multiple shared risk factors including type 2 diabetes mellitus,arterial hypertension,obesity,dyslipidemia,and insulin ***,similarities in their molecular pathophysiologic mechanisms can be detected,since inflammation,oxidative stress,fibrosis,and gut dysbiosis are highly prevalent in these pathologic *** the same time,lines of evidence suggest a genetic predisposition to MAFLD due to gene polymorphisms,such as the PNPLA3 rs738409 g allele polymorphism,which may also propagate renal *** their management,available treatment considerations for obesity(bariatric surgery)and novel antidiabetic agents(glucagon-like peptide 1 receptor agonists,sodiumglucose co-transporter 2 inhibitors)appear beneficial in preclinical and clinical studies of MAFLD and CKD ***,alternative approaches such as melatonin supplementation,farnesoid X receptor agonists,and gut microbiota modulation may represent attractive options in the *** a look to the future,additional adequately sized studies are required,focusing on preventing renal complications in patients with MAFLD and the appropriate management of individuals with concomitant MAFLD and CKD.

关键词： Metabolic dysfunction-associated fatty liver disease Chronic kidney disease Hepatic steatosis inflammation Type 2 diabetes mellitus Obesity

Machine Learning and Medical Devices:The Next Step for Tissue Engineering

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Engineering 2021年第12期7卷 1704-1706页

作者： Hannah A.Pearce Antonios g.Mikos Department of Bioengineering Rice UniversityHoustonTX 77030USA

The pathway for creating and seeing a medical device to market is time-intensive,costly,and demanding[1,2].This is particularly true of devices developed with tissue engineering components within the device[1,3].Machine learning and artificial intelligence have expedited optimization and engineering design in many other engineering disciplines[4,5].

关键词： demanding artificial creating

Raman analysis of chemisorbed tribofilm for metal-on-polyethylene hip joint prostheses

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Biosurface and Biotribology 2021年第1期7卷 1-11页

作者： Risha Rufaqua Martin Vrbka Dušan Hemzal Dipankar Choudhury david Rebenda Ivan Křupka Martin Hartl Faculty of Mechanical Engineering Brno University of TechnologyBrnoCzech Republic Department of Condensed Matter Physics Faculty of ScienceMasaryk UniversityBrnoCzech Republic Nano Mechanics and Tribology Laboratory Department of Mechanical EngineeringUniversity of ArkansasFayettevilleArkansasUSA

The biochemical reaction during the formation of lubricant film the in case of a cobalt-chromium ball on an ultrahigh-molecular weight polyethylene cup was *** types of model synovial fluids and hyaluronic acid(HA)at physiologic concentrations were used in the *** coefficient of friction was measured using a pendulum hip simulator,and Raman spectroscopy was used to perceive chemical reactions between the synovial fluid and implant *** spectra evidenced that the three model fluids and HA chemisorbed onto the cobalt-chromium ***α-helix structure of the model fluid components was detected on the surface of the prosthesis.

关键词： material surface experiment

A green, One-Pot Route to the Biphenyldicarboxylic Acids: Useful Intermediates in Polymer Synthesis

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International Journal of Organic Chemistry 2013年第2期3卷 143-147页

作者： Richard S. Clary Christopher D. Lee William g. Monroe IV david A. Vaughn Ragy T. Ragheb Jack W. Erter III david M. Brown david A. Schiraldi Department of Chemistry Davidson College Davidson NC USA Department of Macromolecular Science & Engineering Case Western Reserve University Cleveland OH USA

Isomeric biphenyldicarboxylic acids have been prepared from halobenzoic acids and aryl boronic acids using an inverse biphasic modification of the Suzuki coupling reaction. In this modification of the Suzuki coupling reaction, both reactants and products are contained in the aqueous phase, with palladium catalyst contained in the organic phase. A phase transfer catalyst is used to contact reactants and catalyst. Multiple cycles, in which the catalyst/organic solvent is contacted with fresh aqueous reactants, generating products with no loss of efficiency, are demonstrated. We believe that this is the first demonstration of Suzuki coupling to produce biphenyldicarboxylic acids, in this case useful as monomers for the production of condensation polymers.

关键词： Biphenyl Carboxylic Acid Suzuki

HOXB13 and other high penetrant genes for prostate cancer

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Asian Journal of Andrology 2016年第4期18卷 530-532页

作者： Patrick g Pilie Veda N giri Kathleen A Cooney Division of Cancer Medicine The University of Texas MD Anderson Cancer Center Houston TX USA Department of Medical Oncology Sidney Kimmel Cancer Center Thomas Jefferson University Philadelphia PA USA Division of Hematology/ Oncology Department of Internal Medicine University of Michigan Medical School and The University of Michigan Comprehensive Cancer Center Ann Arbor MI USA

Cancer initiation and progression is the result of an accumulation of mutations inkey tumor suppressor genes, mismatch repair genes, or oncogenes, which impact cancer cell growth, death, and differentiation. Mutations occurring in cancer tissue are termed somatic; whereas, heritable mutatons that may be passed onto subsequent generations occur in germline DNA. It is these germline mutations that can lead to cancer family syndromeswhereby family members carrying a deleterious germline mutation have an increased susceptibility to certain cancer phenotypes. Common features of hereditary cancer syndromes include early age-of-onset, multiple affected generations, rare tumor types, and/or multiple primary malignancies.

关键词： gENOME-WIDE SCAN SUSCEPTIBILITY gENES INTERNATIONAL CONSORTIUM gERMLINE MUTATION RISK LINKAgE MEN FAMILIES gENETICS BRCA1

Major constraints on shisham(Dalbergia sissoo) plantations and pathological debate on dieback disease in Punjab,Pakistan

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Journal of Forestry Research 2015年第2期26卷 267-271页

作者： Irum Mukhtar R.Bajwa g.Nasim Institute of Agricultural Sciences University of the PunjabQuiad-E-Azam CampusLahore 54590Pakistan

Today,shisham plantations in Punjab,Pakistan face major constraints,especially dieback *** article reviews the multidisciplinary team work by forest and plant pathologists and economists to resolve the confusions in the pathology of dieback *** is intended to be of practical use to the foresters and plant pathologists reporting on this issue.

关键词： Shisham Dieback disease Plantations Forest

Anti-microsporidial effect of thymoquinone on Encephalitozoon intestinalis infection in vitro

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Asian Pacific Journal of Tropical Biomedicine 2020年第1期10卷 42-46页

作者： Ulfet Cetinkaya gülay Sezer Arzuv Charyyeva Halil Bayraktar Health Vocational College Erciyes UniversityKayseriTurkey School of Medicine Department of PharmacologyErciyes UniversityKayseriTurkey genkok genome and Stem Cell Centre Department of Molecular Biology and GeneticsErciyes UniversityKayseriTurkey Life Science Research Centre Faculty of ScienceOstrava UniversityOstravaCzech Republic

Objective:To evaluate the anti-microsporidial effects of the active component of Nigella sativa seeds,thymoquinone,against Encephalitozoon intestinalis using an in vitro ***:Anti-microsporidial effect of thymoquinone against Encephalitozoon intestinalis was evaluated by using various concentrations of thymoquinone(0,1,5,10,15,20,30,35,and 40μM)and sterile dimethyl *** time PCR was used to evaluate the inhibitory effects of thymoquinone on the life cycle of Encephalitozoon ***:The cytotoxic effect of thymoquinone on HEK293 cell line was observed with 30,35,and 40μM concentrations of thymoquinone after 24,48,and 72 hours of *** was observed that 10,15,20,and 30μM concentrations of thymoquinone decreased the spore density compared with the control;however,it was significant only at 30μ***:Thymoquinone shows potent anti-microsporidial effects against Encephalitozoon intestinalis in the in vitro model;however,the toxic concentrations of thymoquinone are also toxic to the host cells.

关键词： Microsporidia Thymoquinone Nigella sativa Antiparasitic Encephalitozoon intestinalis