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作者： Marun J.Abbudi david M.barnett Division of Applied Mechanics Department of Mechanical Engineering Stanford UniversityStanfordCA 94305-4040USA Division of Applied Mechanics Department of Mechanical Engineering Stanford UniversityStanfordCA 94305-4040USA

＜正＞Most previous studies have dealt only with elastically isotropic layers;however,since the majority of materials used in high technology applicatins are anisotropic,the need to account for anisotropic effects becomes *** effects are dealt with in complete generality in the present work using the Stroh formalism coupled with a Fast Fourier Transform *** method is easily implemented for a dislocated multilayered structure,although in this work we present only a numerical example for the Peach- Koehler force on dislocation in a single thin film on a substrate.

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Cost burden following esophagectomy:A single centre observational study

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2255-2269页

作者： Vered Buchholz Dong Kyu Lee david S Liu Ahmad Aly Stephen A barnett Riley Hazard Peter Le Benjamin Kioussis Vijayaragavan Muralidharan Laurence Weinberg Department of Surgery Austin HealthMelbourne 3084VictoriaAustralia Department of Anesthesiology and Pain Medicine Dongguk University Ilsan HospitalSeoul 14566GoyangSouth Korea Department of Surgery Austin HealthThe University of MelbourneMelbourne 3084VictoriaAustralia Department of Anesthesia Austin HealthMelbourne 3084VictoriaAustralia Department of Anesthesia Austin HospitalHeidelberg 3084VictoriaAustralia Department of Critical Care The University of MelbourneMelbourne 3084VictoriaAustralia

BACKGROUND Cost analyses of patients undergoing esophagectomy is valuable for identifying modifiable expenditure drivers to target and curtail costs while improving the quality of *** aimed to define the cost-complication relationship after esophagectomy and delineate the incremental contributions to *** To assess the relationship between the hospital costs and potential cost drivers post esophagectomy and investigate the relationship between the cost-driving variables(predicting variables)and hospital costs(dependent variable).METHODS In this retrospective single center study,the severity of complications was graded using the Clavien-Dindo(CD)classification *** esophagectomy complications were categorized and defined according to consensus *** costing data included the in-hospital costs of the index admission and any unplanned admission within 30 postoperative *** used correlation analysis to assess the relationship between key clinical variables and hospital costs(in United States dollars)to identify cost drivers.A mediation model was used to investigate the relationship between these variables and hospital *** A total of 110 patients underwent primary esophageal *** median admission cost was $47822.7(interquartile range:35670.2-68214.0).The total effects on costs were $13593.9(95%CI:10187.1-17000.8,P<0.001)for each increase in CD severity grade,$4781(95%CI:3772.7-5789.3,P<0.001)for each increase in the number of complications,and $42552.2(95%CI:8309-76795.4,P=0.015)if a key esophagectomy complication *** esophagectomy complications drove the costs directly by $11415.7(95%CI:992.5-21838.9,P=0.032).CONCLUSION The severity and number of complications,and the development of key esophagectomy complications significantly contributed to total hospital *** institutional initiatives and strategies are needed to enhance patient outcomes and minimize costs.

关键词： Anesthesia Esophagectomy Complications Cancer Surgery

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刘慈欣:当《三体》走向世界

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新东方英语（中学版） 2017年第9期 4-7页

作者： david barnett 赵青奇

刘慈欣还在上学的时候，最喜欢看的书是儒勒·凡尔纳的《地心游记》。他发现这本书藏在曾属于父亲的一个旧箱子里。“正是这本书把我变成了一个科幻迷。”刘慈欣说。现年53岁的刘慈欣是一位科幻小说作家，在中国和英语国家都颇有名望。... 详细信息

刘慈欣还在上学的时候，最喜欢看的书是儒勒·凡尔纳的《地心游记》。他发现这本书藏在曾属于父亲的一个旧箱子里。“正是这本书把我变成了一个科幻迷。”刘慈欣说。现年53岁的刘慈欣是一位科幻小说作家，在中国和英语国家都颇有名望。他的小说《三体》在2015年获得了雨果奖。其第二部续作《黑暗森林》的英文版于2015年出版，而第三部《死神永生》也已被翻译成英文，刚刚(编注：英文原文发表于2016年12月)在英国出版。

关键词：刘慈欣世界《地心游记》小说作家英文版英语国家凡尔纳科幻

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Numerical Determination of Stress Fields of and Forces on Line Dislocations in Anisotropic Multilayer Structures

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电子显微学报 1997年第4期 183-184页

作者： Marun J.Abbudi \ L.Y.Pang\ david M.barnett (Division of Applied Mechanics, Department of Mechanical Engineering, Stanford University, Stanford, CA 94305 4040, USA)

ＮｕｍｅｒｉｃａｌＤｅｔｅｒｍｉｎａｔｉｏｎｏｆＳｔｒｅｓＦｉｅｌｄｓｏｆａｎｄＦｏｒｃｅｓｏｎＬｉｎｅＤｉｓｌｏｃａｔｉｏｎｓｉｎＡｎｉｓｏｔｒｏｐｉｃＭｕｌｔｉｌａｙｅｒＳｔｒｕｃｔｕｒｅｓＭａｒｕｎＪ．Ａｂｂｕ... 详细信息

ＮｕｍｅｒｉｃａｌＤｅｔｅｒｍｉｎａｔｉｏｎｏｆＳｔｒｅｓＦｉｅｌｄｓｏｆａｎｄＦｏｒｃｅｓｏｎＬｉｎｅＤｉｓｌｏｃａｔｉｏｎｓｉｎＡｎｉｓｏｔｒｏｐｉｃＭｕｌｔｉｌａｙｅｒＳｔｒｕｃｔｕｒｅｓＭａｒｕｎＪ．ＡｂｂｕｄｉＬ．Ｙ．ＰａｎｇＤａｖｉｄＭ．...

关键词： Stress Fields Determination

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孤独梦想家

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作者： (英)戴维·巴尼特(david M. barnett)

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孤独之心电影院

孤独之心电影院

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作者： (英)戴维·M.巴尼特(david M.barnett)

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Assembly of a parts list ofthe human mitotic cell cycle machinery

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Journal of Molecular Cell Biology 2019年第8期11卷 703-718页

作者： Bruno Giott Sz-Hau Chen Mark W.barnett Tim Regan Tony Ly Stefan Wiemann david A.Hume Tom C.Freeman The Roslin Institute University of Edinburgh Easter Bush Midlothian EH25 9RG Scotland UK Biosciences and Biotechnology Institute EDyP Department CEA Grenoble 17 rue des Martyrs 38054 Grenoble France Wellcome Centre for Cell Biology University of Edinburgh Swann Building Edinburgh EH9 3BF Scotland UK Molecular Genome Analysis (B050) Deutsches Krebsforschungszentrum Im Neuenheimer Feld 580 69120 Heidelberg Germany Mater Research Institute University of Queensland Level 3 Aubigny Place Raymond Terrace South Brisbane Qld 4101 Australia

The set of proteins required for mitotic division remains poorly characterized. Here, an extensive series of correlation analyses of human and mouse transcriptomics data were performed to identify genes strongly and reproducibly associated with cells undergoing S/G2-M phases of the cell cycle. In so doing, 701 cell cycle-associated genes were defined and while it was shown that many are only expressed during these phases, the expression of others is also driven by alternative promoters. Of this list, 496 genes have known cell cycle functions, whereas 205 were assigned as putative cell cycle genes, 53 of which are functionally uncharacterized. Among these, 27 were screened for subcellular localization revealing many to be nuclear localized and at least three to be novel centrosomal proteins. Furthermore, 10 others inhibited cell proliferation upon siRNA knockdown. This study presents the first comprehensive list of human cell cycle proteins, identifying many new candidate proteins.

关键词： cell cycle systems biology gene expression transcriptome network analysis

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Expression of multiple glutamate transporter splice variants in the rodent testis

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Asian Journal of Andrology 2011年第2期13卷 254-265页

作者： Aven Lee Ashley R Anderson Amanda C barnett Anthony Chan david V Pow Centre for Clinical Research Royal Brisbane and Women＇s Hospital The University of Queensland Brisbane QId 4029 Australia

Glutamate is a regulated molecule in the mammalian testis. Extracellular regulation of glutamate in the body is determined largely by the expression of plasmalemmal glutamate transporters. We have examined by PCR, western blotting and immunocytochemistry the expression of a panel of sodium-dependent plasmalemmal glutamate transporters in the rat testis. Proteins examined included： glutamate aspartate transporter （GLAST）, glutamate transporter 1 （GLT1）, excitatory amino acid carrier 1 （EAAC1）, excitatory amino acid transporter 4 （EAAT4） and EAAT5. We demonstrate that many of the glutamate transporters in the testis are alternately spliced. GLAST is present as exon-3- and exon-9-skipping forms. GLT1 was similarly present as the alternately spliced forms GLT1 b and GLTlc, whereas the abundant brain form （GLTla） was detectable only at the mRNA level. EAAT5 was also strongly expressed, whereas EAAC1 and EAAT4 were absent. These patterns of expression were compared with the patterns of endogenous glutamate localization and with patterns of D-aspartate accumulation, as assessed by immunocytochemistry. The presence of multiple glutamate transporters in the testis, including unusually spliced forms, suggests that glutamate homeostasis may be critical in this organ. The apparent presence of many of these transporters in the testis and sperm may indicate a need for glutamate transport by such cells.

关键词： excitatory amino acid transporter glutamate aspartate transporter glutamate transporter 1 sperm splice variant testis transporter

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Brittleness index predictions from Lower barnett Shale well-log data applying an optimized data matching algorithm at various sampling densities

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Geoscience Frontiers 2021年第6期12卷 444-457页

作者： david A.Wood DWA Energy Limited LincolnUnited Kingdom

The capability of accurately predicting mineralogical brittleness index (BI) from basic suites of well logs is desirable as it provides a useful indicator of the fracability of tight *** mineralogical components in rocks is expensive and time ***,the basic well log curves are not well correlated with BI so correlation-based,machine-learning methods are not able to derive highly accurate BI predictions using such data.A correlation-free,optimized data-matching algorithm is configured to predict BI on a supervised basis from well log and core data available from two published wells in the Lower barnett Shale Formation (Texas).This transparent open box (TOB) algorithm matches data records by calculating the sum of squared errors between their variables and selecting the best matches as those with the minimum squared *** then applies optimizers to adjust weights applied to individual variable errors to minimize the root mean square error (RMSE)between calculated and predicted (BI).The prediction accuracy achieved by TOB using just five well logs (Gr,ρb,Ns,Rs,Dt) to predict BI is dependent on the density of data records *** a sampling density of about one sample per 0.5 ft BI is predicted with RMSE~0.056 and R^(2)~*** a sampling density of about one sample per0.1 ft BI is predicted with RMSE~0.008 and R^(2)~*** a stratigraphic height index as an additional (sixth)input variable method improves BI prediction accuracy to RMSE~0.003 and R^(2)~0.999 for the two wells with only 1 record in 10,000 yielding a BI prediction error of>±*** model has the potential to be applied in an unsupervised basis to predict BI from basic well log data in surrounding wells lacking mineralogical measurements but with similar lithofacies and burial *** method could also be extended to predict elastic rock properties in and seismic attributes from wells and seismic data to improve the precision of brittleness index and fracab

关键词： Well-log brittleness index estimates Data record sample densities Zoomed-in data interpolation Correlation-free prediction analysis Mineralogical and elastic influences

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