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Stability Analysis of a Neurocontroller with Kalman Estimator for the Inverted Pendulum Case

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Applied Mathematics 2017年第11期8卷 1602-1618页

作者： Julián Antonio Pucheta Cristian Rodríguez Rivero Carlos alberto salas Martín Herrera Sergio Oscar Laboret departamentos de Electrotecnia y de Electrónica Laboratorio de Investigación Matemática Aplicada a Control (LIMAC) Facultad de Ciencias Exactas Físicas y Naturales-Universidad Nacional de Córdoba Córdoba Argentina departamento de Ingeniería Electrónica Facultad de Tecnología y Ciencias Aplicadas Universidad Nacional de Catamarca Catamarca Argentina

In this paper, a practical analysis of stability by simulation for the effect of incorporating a Kalman estimator in the control loop of the inverted pendulum with a neurocontroller is presented. The neurocontroller is calculated by approximate optimal control, without considering the Kalman estimator in the loop following the Theorem of the separation. The results are compared with a time-varying linear controller, which in noiseless conditions in the state or in the measurement has an acceptable performance, but when it is under noise conditions its operation closes into a state space range more limited than the one proposed here.

关键词： Optimal Control Neurocontroller Inverted Pendulum State Estimation Stability

A multidimensional review of the cash management problem

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Financial Innovation 2023年第1期9卷 1840-1874页

作者： Francisco salas‑Molina Juan A.Rodríguez‑Aguilar Montserrat Guillen Universitat Politècnica de València Ferrándiz y Carbonell03801 AlcoySpain IIIA‑CSIC Campus UAB08913 CerdanyolaSpain Universitat de Barcelona Av.Diagonal69008034 BarcelonaSpain

In this paper,we summarize and analyze the relevant research on the cash manage-ment problem appearing in the ***,we identify the main dimensions of the cash management ***,we review the most relevant contributions in this field and present a multidimensional analysis of these contributions,according to the dimensions of the *** this analysis,several open research questions are highlighted.

关键词： Cash management Models Dimensions Review

Tacrolimus confers lower acute rejection rates and better renal allograft survival compared to cyclosporine

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World Journal of Transplantation 2016年第4期6卷 697-702页

作者： Mahmoud Kamel Manish Kadian Titte Srinivas david Taber Maria Aurora Posadas salas department of Medicine Medical University of South Carolina department of Surgery Medical University of South Carolina

AIM To compare the impact of tacrolimus(FK) and cyclosporine(CYA) on acute rejection and graft survival and to assess the predominant causes of graft loss between patients receiving these two calcineurin inhibitors(CNIs).METHODS Retrospective review of 1835 patients who received a kidney transplant(KTX) between 1999-2012. Patients were grouped based on initial CNI utilized: 1195 in FK group, 640 in CYA group. Data on baseline characteristics, clinical outcomes, and causes of graft loss in both groups were analyzed. RESULTS Cumulative acute rejection rates were 14% in the FK vs 24% in the CYA group. despite more marginal donor characteristics in the FK group, these patients had better graft survival rates compared to the CYA group. Three and five year graft survival rates were 88% and 84% respectively in the FK group compared to 79% and 70% respectively in the CYA group(P ders, FK use was a strong predictor for lower acute rejectionrates [odds ratio(OR) 0.60, 95%CI: 0.45-0.79] and better renal allograft survival(OR 0.740, 95%CI: 0.58-0.94). death with a functioning graft was the most common cause of graft loss in both groups. Common causes of death included cardiovascular disease, infections, and malignancies. Chronic allograft nephropathy was also found to be an important cause of graft loss, being more prevalent in the CYA group. CONCLUSION The use of FK-based maintenance immunosuppression therapy is associated with a significantly lower rate of acute rejection and better graft survival compared to CYA-based regimen. Individualizing immunosuppression through risk-stratified CNI choice may lead to improved outcomes across all spectra of KTX patients.

关键词： Tacrolimus Cyclosporine Renal allograft survival

Empirical Assessment of Bacillus Calmette-Guérin Vaccine to Combat COVID-19

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Computers, Materials & Continua 2022年第1期70卷 213-231页

作者： Nikita Jain Vedika Gupta Chinmay Chakraborty Agam Madan deepali Virmani Lorenzo salas-Morera Laura Garcia-Hernandez department of Computer Science&Engineering Bharati Vidyapeeth’s College of EngineeringNew Delhi110063India department of Electronics&Communication Engineering Birla Institute of TechnologyMesra814142India department of Computer Science&Engineering Bhagwan Parshuram Institute of TechnologyNew Delhi110063India Area of Project Engineering University of CórdobaCórdoba14071Spain

COVID-19 has become one of the critical health issues globally,which surfaced first in latter part of the year *** is the topmost concern for many nations’governments as the contagious virus started mushrooming over adjacent regions of infected *** 1980,a vaccine called Bacillus Calmette-Guérin(BCG)was introduced for preventing tuberculosis and lung *** that have made the BCG vaccine mandatory have witnessed a lesser COVID-19 fatality rate than the countries that have not made it *** paper’s initial research shows that the countries with a longtermcompulsory BCGvaccination system are less affected by COVID-19 than those without a BCG vaccination *** paper discusses analytical data patterns for medical applications regarding COVID-19 impact on countries with mandatory BCG status on fatality *** paper has tackled numerous analytical challenges to realize the full potential of heterogeneous *** analogy is drawn to demonstrate how other factors can affect fatality and infection rates other than BCG vaccination only,such as age groups affected,other diseases,and stringency *** data of Spain,Portugal,and Germany have been taken for a case study of BCG impact analysis.

关键词： Bacillus Calmette-Guérin COVID-19 fatality rate lockdown gross domestic product vaccine

BK viral infection: A review of management and treatment

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World Journal of Transplantation 2023年第6期13卷 309-320页

作者： June Hayrelle Gorriceta Amy Lopez Otbo Genta Uehara Maria Aurora Posadas salas department of Medicine St Francis Hospital-BartlettBartlettTN 38133United States department of Medicine St.Luke’s Medical CenterQuezon 1112Philippines department of Medicine Division of NephrologyMedical University of South CarolinaCharlestonSC 29425United States

BK viral infection remains to be a challenging post-transplant infection,which can result in kidney *** mainstay approach to BK infection is reduction of *** in immunosuppressive regimen with minimization of calcineurin inhibitors,use of mechanistic target of rapamycin inhibitors,and leflunomide have been attempted with variable *** the past few years,investigators have explored potential therapeutic options for BK *** prophylaxis and treatment was found to have no benefit in kidney transplant *** utility of cidofovir is limited by its *** immunoglobulin is becoming a popular option for treatment and prophylaxis for BK infection,as it increases the neutralizing antibody titers against the most common BK virus ***-specific T cell therapy is an emerging treatment option for BK *** this review,we will explore management and therapeutic options for BK infection and recent evidence available in literature.

关键词： BK infection Kidney transplant Treatment Management

Effect of protease supplementation on apparent ileal crude protein and amino acid digestibility of over-processed soybean meals in broilers

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Journal of Animal Science and Biotechnology 2022年第6期13卷 1810-1817页

作者： Sergio Salazar-Villanea Maikol Astúa-Ureña Allison Masís-Montoya Juan I.Herrera-Muñoz Catalina salas-Durán Escuela de Zootecnia Universidad de Costa RicaSan JoséCosta Rica Centro de Investigación en Nutrición Animal Universidad de Costa RicaSan JoséCosta Rica

Background: Nutritional value of proteins in feed ingredients can be negatively affected by hydrothermal processing, which causes large variation in the bioavailability of amino acids(AA) and negatively affects animal productive performance. Supplementation of exogenous proteases could increase the rate of digestion of damaged proteins, thereby increasing overall AA digestibility and bioavailability. The aim was to determine the effect of exogenous protease supplementation on the apparent ileal digestibility(AID) of crude protein(CP) and AA of soybean meals(SBM) with different degrees of hydrothermal processing in ***: The experiment involved a 3 × 2 factorial arrangement, with SBM processing time(commercial SBM or autoclaved for 30 or 60 min at 120 ℃) and protease supplementation(not supplemented and supplemented) as factors. Protease was included at three times the recommended dose(0.06%) and the experimental diets were fed from 15 to 21 ***: The interaction between the effects of SBM processing and protease supplementation was significant for the AID of CP(P = 0.01), Trp(P = 0.01), Gly(P = 0.03) and Pro(P = 0.03), and also for the average daily gain(P = 0.01)and feed conversion ratio(P = 0.04). Increasing the processing time of SBM decreased(P < 0.0001) the AID of all amino acids, whilst the effect of protease supplementation was only significant for the AID of Phe(P = 0.02) and Tyr(P = 0.01).Conclusions: Exogenous protease supplementation at three times the commercial dose does not seem to offset the negative effects of hydrothermal processing of SBM on the apparent ileal digestibility of CP and amino acids or performance of broilers. Whilst positive numerical improvements of digestibility and performance(ADG and FCR)were noticed with protease supplementation at relatively mild processing levels, negative results were obtained with the harsh-processed meals.

关键词： Amino acids Apparent ileal digestibility Broilers Exogenous protease

Analysis of the Per Capita Generation of Municipal Solid Waste by Socioeconomic Strata in Veracruz, Mexico, Using a Statistical Experimental design

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Journal of Chemistry and Chemical Engineering 2012年第2期6卷 138-146页

作者： Lorena de Medina-salas Eduardo CastiUo-Gonzalez Rabindranarth Romero-Lopez Luis Omar Jamed-Boza Chemical Engineering School University Veracruzana Xalapa 91040 Veracruz Mexico Civil Engineering School University Veracruzana Xalapa 91040 Veracruz Mexico

The management of municipal solid waste （MSW） is currently one of the major environmental concerns in Mexico. Therefore, municipalities must develop local programs for prevention and integrated management of MSW based on the data of MSW generation; however, these are scarce and diffuse. It is known that the MSW generation is affected by many factors, including life level. Given the importance of having reliable data, the objective of this study was to determine the per capita MSW generation of a small urban locality in the state of Veracruz and test whether there were significant statistic differences of per capita M SW generation among the life levels. The households were randomly sampled according to the Mexican standard of reference and were classified as popular, middle and residential. The per capita MSW generation determined was 0.355 kg·inhab^-***^-1. This value was lower than the value estimated by the national reference, suggesting that it might be overestimated and consequently lead to errors in estimating installations costs for the MSW treatment. The result of the experimental design revealed that there were significant statistic differences in the per capita MSW generation among the three socioeconomic strata. This study will allow the municipality to establish better strategies within the municipal program and differential rate for the provision of public clean service and it also provides a solid basis for future research under similar conditions.

关键词： Municipal solid waste integrated management per capita generation socioeconomic strata statistical experimentaldesign least significative difference.

Diversity and host assemblage of avian haemosporidians in different terrestrial ecoregions of Peru

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Current Zoology 2022年第1期68卷 27-40页

作者： Luz GARCIA-LONGORIA Jaime MURIEL Sergio MAGALLANES Zaira Hellen VILLA-GALARCE leonila RICOPA Wilson Giancarlo INGA-DIAZ Esteban FONG Daniel VECCO Cesar GUERRA-SALDANA Teresa salas-RENGIFO Wendy FLORES-SAAVEDRA Kathya ESPINOZA Carlos MENDOZA Blanca SALDANA Manuel GONZALEZ-BLAZQUEZ Henry GONZALES-PINEDO Charlene LUJAN-VEGA Carlos alberto del AGUILA Yessica VILCA-HERRERA Carlos alberto PINEDA Carmen REATEGUI Jorge Manuel CARdeNAS-CALLIRGOS Josealberto IANNACONE Jorge Luis MENDOZA Ravinder NMSEHGAL Alfonso MARZAL departamento de Anatomia Biologia Celular y ZoologiaUniversidad de ExtremaduraBadajoz E-506071Spain Molecular Ecology and Evolution Lab Department of BiologyLund UniversitySolvegatan 37SE-22362 LundSweden Instituto Pirenaico de Ecologıa-IPE(CSIC) Avda.Nuestra Senora de la Victoria 16Jaca 22700Spain DIRESA Direccion Regional de SaludLoreto 16001Peru departamento Academico de Microbiologia y Parasitologia.Facultad de Ciencias Biologicas Universidad Nacional de la Amazonia PeruanaIquitos 16001Peru Facultad de Ciencias Agropecuarias Universidad Alas PeruanasLima 15823Peru EverGreen Institute-San Rafael Distrito de IndianaLoreto 16200Peru Observatorio de Aves Loreto(LBO) Distrito de San JuanLoreto 16008Peru Centro Urku de Estudios Amazonicos Tarapoto 22200Peru Servicio Nacional de Areas Naturales Protegidas por el Estado 15036Peru Sanidad Animal-Facultad de Zootecnia Universidad Nacional Agraria La MolinaLima 15012Peru Laboratorio de Microbiologia Facultad de Medicina Veterinaria y ZootecniaUniversidad CientUfica del SurLima 15067Peru Laboratorio de Analisis Clinico Moraleslab SAC MoralesSan Martin 22201Peru Asociacion Ecosistemas Andinos(ECOAN) Cuzco 08002Peru Pharmacology and Toxicology Graduate Group University of CaliforniaDavisDA 95616USA Global Health Initiative Wabash CollegeCrawfordsvilleIN 47933USA Facultad de Ciencias Biologicas Universidad Nacional Mayor de San MarcosLima 15081Peru Facultad de Medicina Veterinaria Universidad Nacional Hermilio ValdizanHuanuco10160Peru Asociacion Peruana de Helmintologia e Invertebrados Afines Lima 15054Peru Laboratorio de Ecologia y Biodiversidad Animal Universidad Nacional Federico VillarrealEl AgustinoLima 15007Peru Laboratorio de Invertebrados Universidad Ricardo Palma-Santiago de SurcoLima 15537Peru department of Biology San Francisco State UniversitySan FranciscoCA 94132USA

Characterizing the diversity and structure of host–parasite communities is crucial to understandingtheir eco-evolutionary *** and related haemosporidian parasites are responsible forfitness loss and mortality in bird species ***,despite exhibiting the greatest ornithologicalbiodiversity,avian haemosporidians from Neotropical regions are quite ***,we analyze the genetic diversity of bird haemosporidian parasites(Plasmodium andHaemoproteus)in 1,336 individuals belonging to 206 bird species to explore for differences in diversityof parasite lineages and bird species across 5 well-differentiated Peruvian *** 70 different haemosporidian lineages infecting 74 bird *** showed that 25 out ofthe 70 haplotypes had not been previously ***,we also identified 81 new host–parasite interactions representing new host records for these haemosporidian *** outcomesrevealed that the effective diversity(as well as the richness,abundance,and Shannon–Weaver index)for both birds and parasite lineages was higher in Amazon basin ***,we also showed that ecoregions with greater diversity of bird species also had highparasite richness,hence suggesting that host community is crucial in explaining parasite *** parasites were found in ecoregions with lower bird diversity,implying that the abundanceand richness of hosts may shape the exploitation strategy followed by haemosporidian *** outcomes reveal that Neotropical region is a major reservoir of unidentified *** studies analyzing host distribution and specificity of these parasites inthe tropics will provide important knowledge about phylogenetic relationships,phylogeography,and patterns of evolution and distribution of haemosporidian parasites.

关键词： Amazonia avian malaria generalist parasite habitat specificity Haemoproteus Plasmodium specialist parasite

Chemical and Functional Properties of Hard-to-Cook Bean (<i>Phaseolus vulgaris</i>) Protein Concentrate

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Food and Nutrition Sciences 2014年第21期5卷 2081-2088页

作者： Maira R. Segura-Campos Jimena Cruz-salas Luis Chel-Guerrero david Betancur-Ancona Facultad de Ingenierí a Quí mica Universidad Aut&#243 noma de Yucatá n M&#233 rida M&#233 xico

The objective of this research was to evaluate the chemical and functional properties of hard-to-cook (HTC) bean (Phaseolus vulgaris) protein concentrate to determine their potential practical applications. The respective protein concentrate was obtained from the flour using isoelectric precipitation and the protein content was 73.03%. Proximate composition and in vitro digestibility were measured to evaluate the chemical properties, and nitrogen solubility, emulsifying capacity, emulsion stability, foaming capacity, foam stability and viscosity were measured to evaluate its functional properties. The proximate composition of the HTC bean (P. vulgaris) flour and protein concentrate registered values of moisture, ash, protein, fat, fiber and NFE of 8.92, 4.52, 21.71%, 4.41%, 4.11% and 65.25% for flour and of 2.68%, 2.54%, 73.03%, 2.77%, 1.31% and 20.35% for protein concentrate. The in vitro digestibility was of 76.7%. The hard-to-cook bean protein concentrate exhibited good functional properties suggesting its use as additive. This concentrate registered solubility values that are ranging from 2.5% to 71.81%. The emulsifying (EC) and foaming capacity (FC) registered values of 89% - 97% and of 7% - 53% at different pH levels, respectively as well as an emulsion (ES) and foaming stability (FS) pH- and time-dependent. The HTC bean (P. vulgaris) protein concentrate registered a viscosity profile dependent of shear rate. The results suggest that HTC bean (P. vulgaris) protein concentrate is a valuable food ingredient or additive.

关键词： Hard-to-Cook Bean Phaseolus vulgaris Protein Concentrate Chemical and Functional Properties