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英国医学杂志中文版 2004年第3期7卷 138-139页

作者： Tom Treasure david waller Simon Swift Julian Peto 王燕 professor Cardiothoracic Unit Guy's Hospital London SEl 9RT consultant thoracic surgeon Glenfield Hospital Leicester LE3 9QP research registrar Thoracic Surgery Guy's Hospital London SEl 9RT professor of epidemiology Section of Epidemiology Institute of Cancer Research Sutton Surrey SM2 5NG

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关键词：根治术外科治疗间皮瘤石棉

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Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds

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Bioactive Materials 2022年第3期7卷 358-372页

作者： Chia-Chen Hsu Julian H.George Sharlayne waller Cyril Besnard david A Nagel Eric J Hill Michael D.Coleman Alexander M.Korsunsky Zhanfeng Cui Hua Ye Institute of Biomedical Engineering Department of Engineering ScienceUniversity of OxfordOX37DQUK MBLEM Department of Engineering ScienceUniversity of OxfordParks RoadOxfordOX13PJUK School of Biosciences College of Health and Life SciencesAston UniversityBirminghamB47ETUK Translational Medicine Research Group Aston Medical SchoolCollege of Health and Life SciencesAston UniversityBirminghamB47ETUK

To reflect human development,it is critical to create a substrate that can support long-term cell survival,differentiation,and *** are promising materials for 3D ***,a bulk structure consisting of dense polymer networks often leads to suboptimal microenvironments that impedes nutrient exchange and cell-to-cell ***,granular hydrogel-based scaffolds were used to support 3D human induced pluripotent stem cell(hiPSC)-derived neural networks.A custom designed 3D printed toolset was developed to extrude hyaluronic acid hydrogel through a porous nylon fabric to generate hydrogel *** and hydrogel granules were combined using a weaker secondary gelation step,forming self-supporting cell laden *** three and seven days,granular scaffolds supported higher cell viability compared to bulk hydrogels,whereas granular scaffolds supported more neurite bearing cells and longer neurite extensions(65.52±11.59μm)after seven days compared to bulk hydrogels(22.90±4.70μm).Long-term(three-month)cultures of clinically relevant hiPSC-derived neural cells in granular hydrogels supported well established neuronal and astrocytic colonies and a high level of neurite extension both inside and beyond the *** approach is significant as it provides a simple,rapid and efficient way to achieve a tissue-relevant granular structure within hydrogel cultures.

关键词： Microgel Hydrogel Hyaluronan iPSC Neural tissue engineering 3D printing

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Performing arts as a social technology for community health promotion in northern Ghana

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Family Medicine and Community Health 2016年第1期4卷 22-36页

作者： Michael Frishkopf Hasan Hamze Mubarak Alhassan Ibrahim Abukari Zukpeni Sulemana Abu david Zakus Faculty of Arts and Faculty of Medicine and Dentistry University of Alberta382 FABEdmonton AB T6H 3S9Canada 9851 waller Court Richmond BC V7E5S9 Canada Grooming Dot Org P.O.Box TL 1324Postal Code 00233House No.CH.EXT 14Bolga RoadAgric AreaTamaleNorthern RegionGhanaWest Africa Grooming Dot Org P.O.Box TL 1817Post Code:00233TamaleNorthern RegionGhanaWest Africa Tamale Youth Home Cultural Group P O Box 601Tamale N/RA Ext.32 HiltopGhanaWest Africa Faculty of Community Studies School of Occupational and Public HealthRyerson UniversityRoom POD249350 Victoria StreetTorontoON M5B 2K3Canada

Objective:We present first-phase results of a performing arts public health intervention,‘Singing and Dancing for Health,’aiming to promote healthier behaviors in Ghana’s impoverished Northern *** hypothesize that live music and dance drama provide a powerful technology to overcome barriers such as illiteracy,lack of adequate media access,inadequate health resources,and entrenched sociocultural *** research objective is to evaluate this ***:In this first phase,we evaluated the effectiveness of arts interventions in improv-ing knowledge and behaviors associated with reduced incidence of malaria and cholera,focusing on basic information and simple practices,such as proper hand *** with the Youth Home Cultural Group,we codeveloped two‘dance dramas’delivering health messages through di-alog,lyrics,and drama,using music and dance to attract spectators,focus attention,infuse emotion,and socialize *** also designed knowledge,attitude,and behavior surveys as measurement *** purposive sampling,we selected three contrasting test villages in the vicinity,contrasting in size and *** cooperation of chiefs,elders,elected officials,and Gha-na Health Service officers,we conducted a baseline survey in each ***,we performed the interventions,and subsequently conducted follow-up *** a more qualitative approach,we also tracked a select subgroup,conducted focus group studies,and collected ***-veys were coded and data were analyzed by Epi ***:Both quantitative and qualitative methods indicated that those who attended the dance drama performances were likelier than those who did not attend to list the causal,preven-tive,and transmission factors of malaria and ***,the same attendees were likelier than nonattendees to list some activities they do to prevent malaria,cholera,and other sanitation-related diseases,proving that dance dramas were highly effective both in raisi

关键词： Music dance drama edutainment community health sanitation malaria Ghana

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