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主动脉瓣、升主动脉分别置换和联合置换术的临床效果

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世界核心医学期刊文摘（心脏病学分册） 2005年第2期1卷 57-58页

作者： Sioris t. david t.e. Ivanov J. 孟欣 Div. Cardiovasc. Surg. toronto G. Toronto Ont. Canada Dr.

Objectives We sought to compare t.e.clinical profile and outcomes of operation s for aortic valve disease and ascending aortic aneurysm in pat.e.ts t.e.ted wit h aortic valve replacement and supracoronary replacement of t.e.ascending aorta or composite replacement of t.e.aortic valve and ascending aorta (Bentall operat ion). Methods From 1990 through 2001, 133 pat.e.ts had aortic valve replacement and supracoronary replacement of t.e.ascending aorta, and 452 pat.e.ts had Benta ll operations. Aortic valve replacement and supracoronary replacement of t.e.asc ending aorta was performed in pat.e.ts who had aortic valve disease and dilation of t.e.ascending aorta, whereas t.e.Bentall operation was performed in pat.e.ts with aortic root abnormality and ascending aortic aneurysm. Mean follow up was 4.6±3.1 years and was 100%complete. Results Pat.e.ts who had aortic valve rep lacement and supracoronary replacement of t.e.ascending aorta were older (61±13 vs 52±16 years, Pe likely to have aortic stenosis, coronary art.e.y disease, and mitral valve disease than those who had Bentall operations. t.e.use of mechanical valves was equal in both groups(42%for aortic valve replacem ent and supracoronary replacement of t.e.ascending aorta and 43%for t.e.Bentall operation). Operative mortality was 5%for pat.e.ts underg oing aortic valve replacement and supracoronary replacement of t.e.ascending aor ta and 4%for pat.e.ts undergoing t.e.Bentall operation (P=.45). Survival at 10 years was 57%±8%for pat.e.ts undergoing aortic valve replacement and supracor onary replacement of t.e.ascending aorta and 74%±4%for pat.e.ts undergoing th e Bentall operation (P=.04), but t.e.type of operation had no effect on survival . Older age, moderate or severe left ventricular dysfunction, active endocarditi s, previous cardiac surgery, and coronary artery disease were independent predic tors of death. t.e.freedom from reoperation at 10 years was 95%±5%for pat.e.t s undergoing aortic valve

关键词：升主动脉置换术主动脉根部人工瓣膜活动性心内膜炎主动脉窦心脏手术并发症风险手术死亡率组织瓣膜

Instance Segmentation of Characters Recognized in Palmyrene Aramaic Inscriptions

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Computer Modeling in engineering & Sciences 2024年第9期140卷 2869-2889页

作者： Adéla Hamplová Alexey Lyavdansky tomášNovák Ondrej Svojše david Franc Arnošt Veselý Czech University of Life Sciences in Prague(CULS) Faculty of Economics and ManagementDepartment of Information EngineeringPrague16500Czech Republic National Research University Higher School of economics(HSe) Faculty of HumanitiesInstitute for Oriental and Classical StudiesMoscow101000The Russian Federation

this study presents a single-class and multi-class instance segmentation approach applied to ancient Palmyrene inscriptions,employing two state-of-t.e.art deep learning algorithms,namely YOLOv8 and Roboflow *** goal is to contribute to t.e.preservation and understanding of historical texts,showcasing t.e.potential of modern deep learning methods in archaeological *** research culminates in several key findings and scientific *** comprehensively compare t.e.performance of YOLOv8 and Roboflow 3.0 in t.e.context of Palmyrene character segmentation—this comparative analysis mainly focuses on t.e.st.e.gths and weaknesses of each algorithm in this *** also created and annotated an extensive dataset of Palmyrene inscriptions,a crucial resource for furt.e. research in t.e.*** dataset serves for training and evaluating t.e.segmentation *** employ comparative evaluation metrics to quantitatively assess t.e.segmentation results,ensuring t.e.reliability and reproducibility of our findings and we present custom visualization tools for predicted segmentation *** study advances t.e.state of t.e.art in semi-automatic reading of Palmyrene inscriptions and establishes a benchmark for future *** availability of t.e.Palmyrene dataset and t.e.insights into algorithm performance contribute to t.e.broader understanding of historical text analysis.

关键词： Optical character recognition instance segmentation Palmyrene ancient languages computer vision

在三尖瓣修复术时使用瓣环成形术环可改善长期预后

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世界核心医学期刊文摘（心脏病学分册） 2007年第1期3卷 41-42页

作者： david t.e. Singh S.K. M.A. Borger 刘相飞 toronto General Hospital 4N-451 200 Elizabeth St Toronto Ont. M5G 2C4 CanadaDr

背景:本研究旨在比较行三尖瓣(tV)修复术时使用或不使用瓣环成形术环对长期预后的影响。方法和结果:1978—2003年在本机构行tV修复术的702例患者中,共有493例行De Vega成形术(未用瓣环成形环组),其余的209例行瓣环成形(用瓣环成形环组)... 详细信息

背景:本研究旨在比较行三尖瓣(tV)修复术时使用或不使用瓣环成形术环对长期预后的影响。方法和结果:1978—2003年在本机构行tV修复术的702例患者中,共有493例行De Vega成形术(未用瓣环成形环组),其余的209例行瓣环成形(用瓣环成形环组)。三尖瓣病理改变在74%的患者中为功能性(继发性)。同时实施的手术包括:80%的患者行二尖瓣手术,33%的患者行主动脉瓣手术,14%的患者行冠状动脉搭桥术。

关键词：瓣环成形术二尖瓣手术冠状动脉搭桥术修复术心脏手术长期存活率超声心动图多变量分析

保留主动脉瓣膜的主动脉根部动脉瘤修复手术的长期效果

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世界核心医学期刊文摘（心脏病学分册） 2006年第12期2卷 58-59页

作者： david t.e. Feindel C.M. Webb G.D. 张步升 Divisions of Cardiovascular Surgery and Cardiology Toronto General Hospital University of Toronto Toronto Ont. Canada Dr.

Objectives: to examine t.e.results of aortic valve sparing for aortic root aneurysm. Methods: two hundred t.e.ty consecutive pat.e.ts who had aortic valve sparing for aortic root aneurysm were prospectively studied with annual clinical assessments and echocardiography. t.e.r mean age was 46±15 years, 40%had Marfan syndrome, 17%had aortic dissection, and 7%had bicuspid aortic valve. Reimplantation of t.e.aortic valve was performed in 167 pat.e.ts and remodeling of t.e.aortic root in 53. Aortic cusp repair was performed in 80 pat.e.ts, and reinforcement of t.e.free margin of one of t.e.cusps with a fine polytetrafluoroethylene(Gore-tex) suture in 48. t.e.mean follow-up was 5.2±3.7 years and it was complete. Results: t.e.e were 3 operative and 13 late deaths. Pat.e.ts’survival at 10 years was 88%±3%. Age older than 65 years, advanced functional class, and ejection fraction less than 40%were independent predictors of death. Moderate aortic insufficiency developed in 7 pat.e.ts and severe insufficiency in 6. Freedom from moderate or severe aortic insufficiency at 10 years was 85%±5%for all pat.e.ts, but it was 94%±4%after reimplantation and 75%±10%after remodeling(P=.04). Five pat.e.ts required aortic valve replacement; t.e.freedom from valve replacement at 10 years was 95%±3%. One case of endocarditis developed 11 years postoperatively. At t.e.latest follow-up, 88%of t.e.pat.e.ts were in functional class I, and 10%were in class Ⅱ. Conclusions: Aortic valvesparing operation is associated with low rates of valve-related complications. t.e.probability of late aortic insufficiency was lower after t.e.reimplantation procedure than after remodeling in our experience.

关键词：主动脉瓣关闭不全主动脉大动脉动脉瘤

Mitochondrial recruit.e.t in myelin:an anchor for myelin dynamics and plasticity?

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Neural Regeneration Research 2024年第7期19卷 1401-1402页

作者： Jean-david M.Gothié timothy e.Kennedy Depart.e.t of Neurology and Neurosurgery Montreal Neurological InstituteMcGill UniversityMontrealQCCanada

Optimal propagation of neuronal electrical impulses depends on t.e.insulation of axons by myelin,produced in t.e.central nervous system by *** is an extension of t.e.oligodendrocyte plasma membrane,which wraps around an axon to form a compact multi-layered *** is composed of a substantially higher proportion of lipids compared to ot.e. biological membranes and enriched in a small number of specialized proteins.

关键词： plasticity insulation dynamics

Management of obstructed colorectal carcinoma in an emergency setting:An update

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 598-613页

作者： efstathios t Pavlidis Ioannis N Galanis t.e.doros e Pavlidis 2nd Propedeutic Depart.e.t of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colorectal carcinoma is common,particularly on t.e.left *** 20%of pat.e.ts,obstruction and ileus may be t.e.first clinical manifestations of a carcinoma that has advanced(stage II,III or even IV).Diagnosis is based on clinical presentation,plain abdominal radiogram,computed tomography(Ct),Ct colonography and positron emission tomography/*** best management strategy in terms of short-term operative or interventional and long-term oncological outcomes re-mains *** t.e.most common left-sided obstruction,t.e.first choice should be eit.e. emergency surgery or endoscopic decompression by self-expen-dable metal stents or *** operative plan should be eit.e. one-stage or two-stage ***-stage resection with on-table bowel decompression and irrigation can be accompanied or not accompanied by proximal defunctioning stoma(colostomy or ileostomy).Primary anastomosis is more convenient but has increased risks of anastomotic leakage and ***-stage resection(Hart-mann’s procedure)is safer and t.e.most widely used despite temporally affecting quality of *** control surgery in high-risk frail pat.e.ts is less frequently performed since it can be successfully substituted with endoscopic stenting or *** t.e.less common right-sided obstruction,one-stage surgical resection is more beneficial than endoscopic *** role of minimally invasive surgery(laparoscopic or robotic)is a subject of *** laparoscopic-assisted management is advantageous to some extent but requires much expertise due to inherent difficult.e. in dissecting t.e.distended colon and t.e.risk of rup-ture and subsequent septic *** decompressing stent as a bridge to elective surgery more substantially decreases t.e.risks of morbidity and mortality than emergency surgery for decompression and has equivalent medium-term overall survival and disease-free survival *** combination with neoadjuvant chemot.e.apy or radiation may have a p

关键词： Acute abdomen Obstructive ileus Colorectal carcinoma emergency surgery Colectomy Intraluminal metal stents

New t.e.ds in diagnosis and management of gallbladder carcinoma

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 13-29页

作者： efstathios t Pavlidis Ioannis N Galanis t.e.doros e Pavlidis ^(nd)Propedeutic Depart.e.t of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder(GB)carcinoma,although relatively rare,is t.e.most common biliary t.e. cholangiocarcinoma with aggressiveness and poor *** is closely associated with cholelithiasis and long-standing large(>3 cm)gallstones in up to 90%of *** ot.e. main predisposing factors for GB carcinoma include molecular factors such as mutated genes,GB wall calcification(porcelain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made by ultrasound,computed tomography(Ct),and,more precisely,magnetic resonance imaging(MRI).Preoperative staging is of great importance in decisionmaking regarding t.e.apeutic *** staging is based on MRI findings,t.e.leading technique for liver metastasis imaging,enhanced three-phase Ct angiography,or magnetic resonance angiography for major vessel *** is also necessary to use positron emission tomography(Pet)-Ct or ^(18)F-FDG Pet-MRI to more accurately detect metastases and any ot.e. occult deposits with active metabolic *** laparoscopy may detect dissemination not ot.e.wise found in 20%-28.6%of *** t.e.t.e.t is needed,including surgical resection,targeted t.e.apy by biological agents according to molecular testing gene mapping,chemot.e.apy,radiation t.e.apy,and *** is of great importance to understand t.e.updated guidelines and current t.e.t.e.t *** extent of surgical intervention depends on t.e.disease stage,ranging from simple cholecystectomy(t1a)to extended resections and including extended cholecystectomy(t1b),with wide lymph node resection in every case or IV-V segmentectomy(t2),hepatic trisegmentectomy or major hepatectomy accompanied by hepaticojejunostomy Roux-Y,and adjacent organ resection if necessary(t3).Laparoscopic or robotic surgery shows fewer postoperative complications and equivalent oncological outcomes when compared to open surgery,but much at.e.tion must be paid to avoiding *** addition to surgery,novel targe

关键词： Biliary tract neoplasms extrahepatic cholangiocarcinoma Gallbladder carcinoma Gallbladder diseases Biliary t.e. diseases Gastrointestinal malignancies

A systematic scoping review of study methodology for randomized controlled trials investigating probiotics in athletic and physically active populations

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Journal of Sport and Health Science 2024年第1期13卷 61-71页

作者： Alex e.Mohr david B.Pyne Geovana Silva Fogaça Leite Deborah Akins Jamie Pugh College of Health Solutions Arizona State UniversityPhoenixAZ 85004USA Research Institute for Sport and exercise University of CanberraCanberraACT 2617Australia Laboratory of Functional Fermented Food Faculty of Pharmaceutical SciencesUniversity of São PauloSão Paulo 05508-030Brazil Research Institute for Sport and exercise Sciences Liverpool John Moores UniversityLiverpool L33AFUK

Background:t.e.purported ergogenic and health effects of probiotics have been a topic of great intrigue among researchers,practitioners,and t.e.lay public *** has also been an increased research focus within t.e.realm of sports science and exercise medicine on t.e.athletic gut ***,compared to ot.e. ergogenic aids and dietary supplements,probiotics present unique study *** objectives of this systematic scoping review were to identify and characterize study methodologies of randomized controlled trials investigating supplementation with probiotics in athletes and physically active ***:Four databases(MeDLINe,CINAHL,Cochrane CeNtRAL,and Cochrane Database of Systematic Reviews)were searched for randomized controlled studies involving healthy athletes or physically active *** intervention with probiotics and inclusion of a control and/or placebo group were *** peer-reviewed articles in english were considered,and t.e.e were no date *** were extracted and presented in tabular form to detail study protocols,characteristics,and *** in randomized controlled trials was determined with t.e.RoB 2.0 ***:A total of 45 studies were included in t.e.review,with 35 using a parallel group design and 10 using a cross-over *** half t.e.studies used a single probiotic and t.e.ot.e. half a multi-strain *** probiotic dose ranged from 2×10^(8)to 1×10^(11)colony forming units daily,and t.e.length of intervention was bet.e.n 7 and 150 *** than half t.e.studies directly assessed gastrointestinal symptoms,gut permeability,or t.e.gut *** sex ratio of participants was heavily weighted toward males,and only 3 studies exclusively investigated ***-level adverse events were reported in only 2 studies,although t.e.methodology of reporting varied *** risk of bias was generally low,although details on randomization were lacking in some s

关键词： exercise experimental methodology Gastrointestinal symptoms Gut microbiota Probiotic supplementation

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美国页岩油气地质特征及勘探开发进展

石油勘探与开发 2024年第4期51卷 807-828页

作者： MCMAHON t P LARSON t.e.ZHANG t SHUSteR M 美国德克萨斯大学奥斯汀分校杰克逊地质科学学院经济地质局奥斯汀78758-4445德克萨斯州美国

基于美国页岩油气勘探开发历程的回顾,对主要页岩盆地的地质演化、主要页岩层系的油气地质特征及勘探开发进展进行系统梳理和总结。美国重要页岩盆地的富烃页岩主要发育于6个地质时期:中奥陶世、中—晚泥盆世、早石炭世(中—晚密西西比... 详细信息

基于美国页岩油气勘探开发历程的回顾,对主要页岩盆地的地质演化、主要页岩层系的油气地质特征及勘探开发进展进行系统梳理和总结。美国重要页岩盆地的富烃页岩主要发育于6个地质时期:中奥陶世、中—晚泥盆世、早石炭世(中—晚密西西比世)、早二叠世、晚侏罗世和晚白垩世(塞诺曼期—土伦期),构造沉积环境主要包括克拉通内盆地、前陆盆地和被动大陆边缘盆地。古生界富烃页岩主要分布于以下6个盆地:阿巴拉契亚盆地(尤蒂卡页岩和马塞勒斯页岩)、阿纳达科盆地(伍德福德页岩)、威利斯顿盆地(巴肯页岩)、阿卡马盆地(费耶特维尔页岩)、沃思堡盆地(巴内特页岩)和二叠盆地(狼营组和斯帕瑞组/骨泉组页岩)。中生界富烃页岩主要发育在西墨西哥湾盆地(海恩斯维尔组和鹰滩组)和落基山盆地群(以丹佛和粉河盆地的尼尔布拉勒组页岩为主)。通过对各页岩区带的详细分析发现,页岩的岩相和矿物成分存在差异,“页岩储层”并非只是页岩,很多情况下页岩油气还产自粉砂岩和碳酸盐岩等多种岩石类型。美国的页岩油气资源丰富,页岩油地质资源量超过0.246×1012 t,页岩气地质资源量超过290×1012 m3。在开启“页岩革命”的水平井水力压裂技术出现之前,美国经过了长达20年的勘探开发实践和理论技术积累。自2007年至2023年,美国页岩油气产量从约11.2×104t/d油当量增加到超过300.0×104t/d油当量,2017年页岩油气产量超过了常规油气,2023年在油气总产量中的占比增加到60%以上。页岩油气的开发主要得益于钻完井技术的改进,“立体开发”的攻关,以及重复压裂、提高原油采收率和“U”形井等技术的应用。基于美国丰富的页岩资源基础和技术的不断进步,页岩油气的产量将继续为全美的油气生产做出更大贡献。

关键词：美国页岩油页岩气页岩储层非常规储层油气产量资源评价