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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia s.Rex david J.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National science Foundation(NsF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

Making bridges between preclinical and clinical insights into age-related cognitive decline

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Neural Regeneration Research 2025年第8期20卷 2321-2322页

作者： david VC Brito Clévio Nóbrega Algarve Biomedical Center-Research Institute(ABC-RI) Campus GambelasFaroPortugal Algarve Biomedical Center-(ABC) Campus GambelasFaroPortugal Faculty of Medicine and Biomedical sciences(FMCB) University of AlgarveGambelas CampusFaroPortugal

With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th... 详细信息

关键词： bridges becoming insight

sizing and siting of Battery Energy storage systems:A Colombian Case

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Journal of Modern Power systems and Clean Energy 2022年第3期10卷 700-709页

作者： Alvaro Avendano pena david Romero-Quete Camilo A.Cortes Department of Electrical and Electronics Engineering Universidad Nacional de ColombiaBogotaColombia

This paper presents a mixed-integer linear programming(MILP)formulation for sizing and siting of battery energy storage systems(BEsss).The problem formulation seeks to minimize both operation costs and BEss *** proposed model includes restrictions of the conventional securityconstrained unit commitment problem,a piece-wise linear approximation to model power losses,and a linear model of hydro generation *** proposed model is tested in a 6-bus test system and a 15-bus system representing the Colombian power *** the two studied systems,simulation results show that the reduction of operation costs due to the installation of BEsss compensates the investments,under some of the considered technical cost ***,results show that adequate sizing and siting of BEsss reduce renewable energy curtailment in the Colombian power system with high penetration of fluctuating renewable generation.

关键词： Battery energy storage curtailment sizing and siting renewable energy

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Temporal aiming

Light(science & Applications) 2020年第1期9卷 741-752页

作者： Victor Pacheco-pena Nader Engheta school of Mathematics Statistics and PhysicsNewcastle UniversityNewcastle Upon Tyne NE17RUUK Department of Electrical and systems Engineering University of PennsylvaniaPhiladelphiaPA 19104USA

Deflecting and changing the direction of propagation of electromagnetic waves are needed in multiple applications,such as in lens-antenna systems,point-to-point communications and *** this realm,metamaterials have been demonstrated to be great candidates for controlling wave propagation and wave-matter interactions by offering manipulation of their electromagnetic properties at *** have been studied mainly in the frequency domain,but their temporal manipulation has become a topic of great interest during the past few years in the design of spatiotemporally modulated artificial *** this work,we propose an idea for changing the direction of the energy propagation of electromagnetic waves by using time-dependent metamaterials,the permittivity of which is rapidly changed from isotropic to anisotropic values,an approach that we call temporal *** so doing,here,we show how the direction of the Poynting vector becomes different from that of the *** scenarios are analytically and numerically evaluated,such as plane waves under oblique incidence and Gaussian beams,demonstrating how proper engineering of the isotropic-anisotropic temporal function of ε_(r)(t)can lead to a redirection of waves to different spatial locations in real time.

关键词： anisotropic wave oblique

Current state-of-the-art review of footwear–ground friction

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Friction 2024年第10期12卷 2188-2204页

作者： david REBENDA Tomáš sÁHA Footwear Research Centre University InstituteTomas Bata University in ZlinZlin 76001Czech Republic Faculty of Mechanical Engineering Brno University of TechnologyBron 61600Czech Republic

The most important role of footwear is to ensure safe,functional walking,and foot *** the proper functionality of not only the work shoes,the anti-slip behavior of the shoe under various conditions and environments plays an important role in the prevention of slips,trips,falls,and consequent *** article is intended to review the current understanding of the frictional mechanisms between shoe outsoles and various counterfaces that impact the evaluation of outsole *** research focuses on the mechanisms driving outsole friction on different ground surfaces or the definition and description of parameters that influence outsole ***,the review discusses the effect of various surface contaminants on footwear ***,challenges and outlooks in the field of footwear outsoles are briefly mentioned.

关键词： shoe outsole composite slipperiness coefficient of friction(COF) adhesion safe walk

Toward a neurobiology of auditory object perception： What can we learn from the songbird forebrain？

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Current Zoology 2011年第6期57卷 671-683页

作者： Kai LU, david s. VICARIO Department of Psychology Rutgers University Piscataway NJ 08854 USA

In the acoustic world, no sounds occur entirely in isolation; they always reach the ears in combination with other sounds. How any given sound is discriminated and perceived as an independent auditory object is a challenging question in neu- roscience. Although our knowledge of neural processing in the auditory pathway has expanded over the years, no good theory ex- ists to explain how perception of auditory objects is achieved. A growing body of evidence suggests that the selectivity of neurons in the auditory forebrain is under dynamic modulation, and this plasticity may contribute to auditory object perception. We propose that stimulus-specific adaptation in the auditory forebrain of the songbird （and perhaps in other systems） may play an important role in modulating sensitivity in a way that aids discrimination, and thus can potentially contribute to auditory object perception.

关键词： songbird Object perception Auditory scene analysis Neural selectivity Plasticity stimulus-specific adaptation

strategies to avoid a missed diagnosis of co-occurring concussion in post-acute patients having a spinal cord injury

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Neural Regeneration Research 2015年第6期10卷 859-861页

作者： david s.Kushner Department of Physical Medicine & Rehabilitation University of Miami Miller School of Medicine

Research scientists and clinicians should be aware that missed diagnoses of mild-moderate traumatic brain injuries in post-acute patients having spinal cord injuries may approach 60-74% with certain risk factors, potentially causing clinical consequences for patients, and confounding the results of clinical research studies. Factors leading to a missed diagnosis may include acute trauma-related life-threatening issues, sedation/intubation, subtle neuropathology on neuroimaging, failure to collect Glasgow Coma scale scores or duration of posttraumatic amnesia, or lack of validity of this information, and overlap in neuro-cognitive symptoms with emotional responses to spinal cord injuries. strategies for avoiding a missed diagnosis of mild-moderate traumatic brain injuries in patients having a spinal cord injuries are highlighted in this perspective.

关键词： traumatic brain injury spinal cord injuries dual diagnosis diagnosis complications rehabilitation post-concussion syndrome brain concussion

An Architecture for software Engineering Gamification

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Tsinghua science and Technology 2020年第6期25卷 776-797页

作者： Oscar Pedreira Felix Garcia Mario Piattini Alejandro Cortinas Ana Cerdeira-pena the Universidade da Coruna Centro de Investigacion CITICLaboratorio de Bases de DatosFacultade de InformaticaElvinaA Coruna15071Spain the Universidad de Castilla-La Mancha Grupo AlarcosEscuela Superior de InformaticaPaseo de la Universidad4Ciudad Real13071Spain.

Gamification has been applied in software engineering to improve quality and results by increasing people’s motivation and engagement.A systematic mapping has identified research gaps in the field,one of them being the difficulty of creating an integrated gamified environment comprising all the tools of an organization,since most existing gamified tools are custom developments or *** this paper,we propose a gamification software architecture that allows us to transform the work environment of a software organization into an integrated gamified environment,i.e.,the organization can maintain its tools,and the rewards obtained by the users for their actions in different tools will mount *** developed a gamification engine based on our proposal,and we carried out a case study in which we applied it in a real software development *** case study shows that the gamification engine has allowed the company to create a gamified workplace by integrating custom-developed tools and off-the-shelf tools such as Redmine,TestLink,or JUnit,with the gamification *** main advantages can be highlighted:(i)our solution allows the organization to maintain its current tools,and(ii)the rewards for actions in any tool accumulate in a centralized gamified environment.

关键词： gamification software engineering gamification architecture gamification engine

small molecules to prevent the neurodegeneration caused by α-synuclein aggregation

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Neural Regeneration Research 2020年第12期15卷 2260-2261页

作者： samuel pena-Díaz Jordi Pujols salvador Ventura Institut de Biotecnologia i Biomedicina Departament de Bioquímica i Biologia MolecularUniversitat Autònoma de BarcelonaBellaterraSpain

Parkinson’s disease (PD) is a neurodegenerative disorder belonging to a group of human pathologies known as synucleinopathies,which includes multiple system atrophy or dementia with Lewy bodies (spillantini et al.,1998).These diseases share a common neuropathological feature,the presence ofα-synuclein (α-syn) deposits,although they differ in the cellular and anatomical compartment in whichα-syn inclusions *** affects more than 1% of people over 60 years of age,thus being the second most prevalent neurodegenerative disease in the world and the most common synucleinopathy.

关键词： al. diseases atrophy