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Childhood Exposure to Air Pollution as a Potential Contributor of Chronic Non-Respiratory Inflammatory Disorders: A Longitudinal Prospective Cohort Study in Hamilton, Canada

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Journal of Environmental Protection 2013年第8期4卷 779-788页

作者： Caroline Barakat-Haddad Susan Elliott david pengelly Department of Anthropology University of Toronto Scarborough Toronto Canada Department of Medicine McMaster University Hamilton Canada Faculty of Applied Health Sciences University of Waterloo Waterloo Canada

This study examines the relationship between childhood exposure to air pollution and diagnosis with chronic non-respiratory health outcomes in adulthood. This prospective cohort study uses data collected in the 1970/1980s from 395 children, including exposure to air pollution. Over thirty years later, a survey collected data on various health outcomes, including diagnosis with arthritis, high blood pressure, long-term skin conditions, and hay fever allergies. Logistic regression modeling was performed to examine the relative contribution of childhood exposure to air pollution on chronic non-respiratory health outcomes in adulthood. Childhood exposure to SO2 emerged as a significant predictor of arthritis (OR = 2.73, 95% CI 1.20 - 6.18) and high blood pressure (OR = 2.82, 95% CI 1.23 - 6.47). Other significant predictors include respiratory symptoms during childhood, family income during childhood and adulthood, property tenure, employment status, residential exposures, life events, physical activity, and body mass index. Childhood exposure to air pollution did not emerge as a significant predictor of long-term skin conditions or hay fever allergies. Findings contribute to the debate on the health effects of air pollution, indicating that the health impacts of childhood exposure to air pollution may include chronic inflammatory disorders in adulthood.

关键词： Air Pollution Health Development Hay Fever Arthritis Hypertension Skin Diseases

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