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Chronic methadone use,poor bowel visualization and failed colonoscopy:A preliminary study

World journal of Gastroenterology 2012年第32期18卷 4350-4356页

作者： Siddharth Verma joshua Fogel david j beyda Brett Bernstein Vincent Notar-Francesco Smruti R Mohanty Department of Internal Medicine Division of GastroenterologyNew York Methodist HospitalWeill Cornell Medical CollegeBrooklynNY 11215United States Department of Finance and Business Management Brooklyn CollegeBrooklynNY 11210United States Department of Internal Medicine Division of GastroenterologySUNY Downstate Medical Center University Hospital of BrooklynLong Island College HospitalBrooklynNY 11201United States Department of Internal Medicine Division of GastroenterologyBeth Israel Medical CenterAlbert Einstein College of MedicineNew YorkNY 10003United States

AIM:To examine effects of chronic methadone usage on bowel visualization,preparation,and repeat ***:In-patient colonoscopy reports from October,2004 to May,2009 for methadone dependent(MD) patients were retrospectively evaluated and compared to matched opioid naive controls(C).Strict criteria were applied to exclude patients with risk factors known to cause constipation or gastric *** reports of all eligible patients were analyzed for degree of bowel visualization,assessment of bowel preparation(good,fair,or poor),and whether a repeat colonoscopy was *** visualization was scored on a 4 point scale based on multiple prior studies:excellent = 1,good = 2,fair = 3,or poor = *** of variance(ANOVA) and Pearson χ 2 test were used for data *** analysis included correlation between methadone dose and colonoscopy *** variables significantly differing between MD and C groups were included in both univariate and multivariate logistic regression analyses.P values were two sided,and < 0.05 were considered statistically ***:After applying exclusionary criteria,a total of 178 MD patients and 115 C patients underwent a colonoscopy during the designated study period.A total of 67 colonoscopy reports for MD patients and 72 for C were included for data *** and gender matched controls were randomly selected from this population to serve as controls in a numerically comparable *** average age for MD patients was 52.2 ± 9.2 years(range:32-72 years) years compared to 54.6 ± 15.5 years(range:20-81 years) for C(P = 0.27).Sixty nine percent of patients in MD and 65% in C group were males(P = 0.67).When evaluating colonoscopy reports for bowel visualization,MD patients had significantly greater percentage of solid stool(i.e.,poor visualization) compared to C(40.3% vs 6.9%,P < 0.001).Poor bowel preparation(35.8% vs 9.7%,P < 0.001) and need for repeat colonoscopy(32.8% vs 12.5%,P = 0.004)

关键词： Colonoscopy Methadone Opioid Inadequate bowel preparation Colonoscopy preparation Methadone dose

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儿科法定药物简化计算表

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国外医学.护理学分册 1985年第6期6卷 316-317页

作者： beyda D H 阮国涛

引言在儿科法规范畴内进行的药物剂量计算可能会出现实际问题,在“急救”中对一名不常从事儿科工作者来说,很难记住每公斤毫克剂量数。我们设计了一种简化的推算表,它免除了繁琐的心算以及在“急救”时用药过程中可能出现的错误。卡片... 详细信息

引言在儿科法规范畴内进行的药物剂量计算可能会出现实际问题,在“急救”中对一名不常从事儿科工作者来说,很难记住每公斤毫克剂量数。我们设计了一种简化的推算表,它免除了繁琐的心算以及在“急救”时用药过程中可能出现的错误。卡片的反面列有计算滴注速度、估计体重、气管内导管口径以及血压等各种公式。

关键词：气管内导管血压剂量用药量儿科哑科抗心律失常药利多卡因昔罗卡因

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