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地质找矿论丛 1999年第4期14卷 76-82页

作者：苗来成 Yu-min.QIU 关康 NealMcNaughton 裘有守罗镇宽 davidgroves 天津地质研究院天津300061 CentreforStrategicMineralDeposits DepartmentofGeologyandGeophysicstheUniversityofWestemAustralia

哈达门沟金矿床位于华北地台北缘西段,产于新太古代乌拉山岩群变质岩系中。矿床以发育一系列含金钾长石-石英脉为特征,这些钾长石-石英脉沿近东西向的韧、脆性叠加断裂成群产出。钾长石化是最发育的近矿围岩蚀变。采用离子探针(SHRIMP)... 详细信息

哈达门沟金矿床位于华北地台北缘西段,产于新太古代乌拉山岩群变质岩系中。矿床以发育一系列含金钾长石-石英脉为特征,这些钾长石-石英脉沿近东西向的韧、脆性叠加断裂成群产出。钾长石化是最发育的近矿围岩蚀变。采用离子探针(SHRIMP)对矿体边部的钾长石化蚀变岩锆石U-Pb 定年结果表明:矿化钾长石化蚀变岩的年龄为132±2 Ma。由于钾长石化蚀变岩本身被金矿化,因此金矿化年龄小于或接近于132±2 Ma,应为燕山晚期成矿。

关键词：哈达门沟金矿床成矿时代锆石地质特征

Lessons learned:Symbiotic autonomous robot ecosystem for nuclear environments

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IET Cyber-Systems and Robotics 2023年第4期5卷 63-86页

作者： Daniel Mitchell Paul Dominick Emor Baniqued Abdul Zahid Andrew West Bahman Nouri Rahmat Abadi Barry Lennox Bin Liu Burak Kizilkaya david Flynn david John Francis Erwin Jose Lopez Pulgarin Guodong Zhao Hasan Kivrak Jamie Rowland Douglas Blanche Jennifer david Jingyan Wang Joseph Bolarinwa Kanzhong Yao Keir groves Liyuan Qi Mahmoud A.Shawky Manuel Giuliani Melissa Sandison Olaoluwa Popoola Ognjen Marjanovic Paul Bremner Samuel Thomas Harper Shivoh Nandakumar Simon Watson Subham Agrawal Theodore Lim Thomas Johnson Wasim Ahmad Xiangmin Xu Zhen Meng Zhengyi Jiang James Watt School of Engineering Autonomous Systems and Connectivity DivisionUniversity of GlasgowGlasgowUK Department of Electrical and Electronic Engineering The University of ManchesterManchesterUK Bristol Robotics Laboratory University of the West of EnglandBristolUK Heriot-Watt University EdinburghUK

Nuclear facilities have a regulatory requirement to measure radiation levels within Post Operational Clean Out(POCO)around nuclear facilities each year,resulting in a trend towards robotic deployments to gain an improved understanding during nuclear decommissioning *** UK Nuclear Decommissioning Authority supports the view that human-in-the-loop(HITL)robotic deployments are a solution to improve procedures and reduce risks within radiation characterisation of nuclear *** authors present a novel implementation of a Cyber-Physical System(CPS)deployed in an analogue nuclear environment,comprised of a multi-robot(MR)team coordinated by a HITL operator through a digital twin *** development of the CPS created efficient partnerships across systems including robots,digital systems and *** was presented as a multi-staged mission within an inspection scenario for the hetero-geneous Symbiotic Multi-Robot Fleet(SMuRF).Symbiotic interactions were achieved across the SMuRF where robots utilised automated collaborative governance to work together,where a single robot would face challenges in full characterisation of *** contributions include the demonstration of symbiotic autonomy and query-based learning of an autonomous mission supporting scalable autonomy and autonomy as a *** coordination of the CPS was a success and displayed further challenges and improvements related to future MR fleets.

关键词： cyber-systems field robotics hazardous inspection human robot interaction industrial robotics mobile robots multi-agent systems multi-robot systems robotics service robots

Micro/nano Indentation and Single Grit Diamond Grinding Mechanism on Ultra Pure Fused Silica

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Chinese Journal of Mechanical Engineering 2011年第6期24卷 963-970页

作者： ZHAO Qingliang GUO Bing STEPHENSIN david CORBETT John School of Mechatronics Engineering Harbin Institute of Technology Harbin 150001 China Materials Department Cranfield University Cranfield Bedford MK43 OAL UK School of Applied Sciences Cranfield University Cranfield Bedford MK43 OAL UK

The existing research about ductile grinding of fused silica glass was mainly focused on how to carry out ductile regime material removal for generating very ＂smoothed＂ surface and investigate the machining-induced damage in the grinding in order to reduce or eliminate the subsurface *** brittle/ductile transition behavior of optical glass materials and the wear of diamond wheel are the most important factors for ductile grinding of optical *** this paper,the critical brittle/ductile depth,the influence factors on brittle/ductile transition behavior,the wear of diamond grits in diamond grinding of ultra pure fused silica（UPFS） are investigated by means of micro/nano indentation technique,as well as single grit diamond grinding on an ultra-stiff machine tool,Tetraform ＂C＂.The single grit grinding processes are in-process monitored using acoustic emission（AE） and force dynamometer *** wear of diamond grits,morphology and subsurface integrity of the machined groves are examined with atomic force microscope（AFM） and scanning electron microscope（SEM）.The critical brittle/ductile depth of more than 0.5 μm is *** compared to the using roof-like grits,by using pyramidal diamonds leads to higher critical depths of scratch with identical grinding ***,the influence of grit shapes on the critical depth is not significant as *** grinding force increased linearly with depth of cut in the ductile removal regime,but in brittle removal regime,there are large fluctuations instead of forces *** SEM photographs of the cross-section profile show that the median cracks dominate the crack patterns beneath the single ***,The SEM photographs show multi worn patterns of diamond grits,indicating an inhomogeneous wear mechanism of diamond grits in grinding of fused silica with diamond grinding *** proposed research provides the basal technical theory for improving the ultra-precision grinding of UPFS.

关键词： ultra pure fused silica (UPFS) micro/nano indentation single grit diamond grinding ductile material removal subsurface integrity diamond grits wear

慢性阻塞性肺疾病与哮喘研究中对重症监护病房患者预后悲观所产生的影响：英国多中心观察队列研究

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英国医学杂志中文版 2008年第2期11卷 84-86页

作者： Martin J Wildman consultant chest Bamaby C Reeves Colin Sanderson Jayne groves Centre, Aberdeen Kathy Rowan david Harrison Duncan Young 苏瑾(译) 代华平(校) Northern General Hospital Sheffield Lndon School of Hygiene and Tropical Medicine London readerin health setvices research Birmingham Hospital Birmingham Department of Occupational and Environmental Medicine Liberty Safe Work Research Intensive Care National Audit and Reserch Centre London senior statistician Adult Intensive Care Unit John Radcliffe Hospital. Oxford 不详

目的确定临床医生对入住重症监护病房（ICU）的COPD急性加重期患者预后的预测与实际结果是否一致。设计前瞻性队列研究。地点英国92个ICU及3个呼吸机依赖病房。参与者832例COPD或哮喘急性加重或COPD合并哮喘患者，表现气促、呼吸衰竭或... 详细信息

目的确定临床医生对入住重症监护病房（ICU）的COPD急性加重期患者预后的预测与实际结果是否一致。设计前瞻性队列研究。地点英国92个ICU及3个呼吸机依赖病房。参与者832例COPD或哮喘急性加重或COPD合并哮喘患者，表现气促、呼吸衰竭或精神状态改变，年龄在45岁及以上。结局评估指标由临床医生预测的结果以及实际观察的180天存活率。结果517例患者（62％）存活到180天。临床医生预测的180天存活率却是悲观的，平均只有49％。依照临床医生的预测，1／5预后最差的存活率仅为10％，而实际存活率却是40％。来自于覆盖英国74％的ICU数据库的信息提示，参与研究和未参与研究的ICU并没有实质性差别。在同一个ICU中入选患者与未入选患者的病情相似。结论因为决定COPD或哮喘患者是否需要气管插管，入住ICU取决于临床医生对其预后的预测．因此，一些本也许会生存下来的患者却由于那些没有根据的对其预后的悲观预测，而很可能被拒绝收入ICU。

关键词：前瞻性队列研究重症监护病房哮喘患者慢性阻塞性肺疾病预后英国悲观多中心

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肺PET图像的定量分析:挑战和机遇

中华核医学与分子影像杂志 2019年第11期39卷 698-704页

作者：陈聪霞(译) 李文婵(译) 郭悦(译) 姚稚明(审校者) Delphine L.Chen Joseph Cheriyan Edwin R.Chilvers Gourab Choudhury Christopher Coello Martin Connell Marie Fisk Ashley M.groves Roger N.Gunn Beverley F.Holman Brian F.Hutton Sarah Lee William MacNee Divya Mohan david Parr Deepak Subramanian Ruth Tai-Singer Kris Thielemans Edwin J.R.van Beek Laurence Vass Jeremy W.Wellen Ian Wilkinson Frederick J.Wilson 北京医院核医学科、国家老年医学中心 100730 Mallinckrodt Institute of Radiology Washington University School of MedicineSt.LouisMissouri Department of Medicine University of CambridgeCambridgeUnited Kingdom Cambridge University Hospitals NHS Foundation Trust CambridgeUnited Kingdom Queen's Medical Research Institute University of EdinburghEdinburghUnited Kingdom Imanova Ltd. London y United Kingdom Institute of Nuclear Medicine University College LondonLondonUnited Kingdom Department of Medicine Imperial College LondonLondonUnited Kingdom Medical Image Analysis Consultant LondonUnited Kingdom Clinical Discovery Respiratory Therapy Area UnitGlaxoSmithKline R&DKing of PrussiaPennsylvania University Hospitals Coventry and Warwickshire CoventryUnited Kingdom Derby Teaching Hospitals NHS Foundation Trust DerbyUnited Kingdom Worldwide Research and Development PfizerInc.CambridgeMassachusetts Experimental Medicine Imaging GlaxoSmithKlineStevenageUnited Kingdom

数百万人受呼吸系统疾病的影响,导致巨大的全球性健康困扰。由于目前对导致呼吸系统疾病发展和进展的潜在机制认识不足,治疗选择仍然有限。为克服此局限和理解相关分子变化,将无创影像技术如PET和SPECT用于探索生物标志物,其中18F-脱氧... 详细信息

数百万人受呼吸系统疾病的影响,导致巨大的全球性健康困扰。由于目前对导致呼吸系统疾病发展和进展的潜在机制认识不足,治疗选择仍然有限。为克服此局限和理解相关分子变化,将无创影像技术如PET和SPECT用于探索生物标志物,其中18F-脱氧葡萄糖(FDG)PET显像的研究最多。由于肺内组织、气体、血液和水的构成比变异,定量分析肺的分子影像数据仍具挑战性。这些成分的比例随着肺部疾病的不同而不同,因此有不同的定量分析方法来显示这种变化,但迄今为止还没有开发出对数据标准化的方法。该文回顾了肺部疾病中18F-FDG PET定量分析方法的数据,聚焦于解释肺内成分变化的方法,解读衍生参数。分析的疾病包括急性呼吸窘迫综合征、慢性阻塞性肺疾病、肺间质性疾病如特发性肺纤维化。基于对既往文献、进行中的研究以及作者间讨论的回顾,作者提出了建议性的注意事项,以协助解读从这些方法及未来研究设计中衍生的参数。

关键词：肺肺部炎症分子成像正电子发射计算机断层显像

SPIRIT 2013声明：定义临床研究方案的标准条目

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中国循证医学杂志 2013年第12期13卷 1501-1507页

作者： An-Wen Chan Jennifer M.Tetzlaff Douglas G.Altman Andreas Laupacis Peter C.GΦtzsche Karmela Krleza-Jeri AsbjΦrn Hróbjartsson Howard Mann Kay Dickersin Jesse A.Berlin Caroline J.Doré Wendy R.Parulekar William S.M.Summerskill Trish groves Kenneth F.Schulz Harold C.Sox Frank W.Rockhold Drummond Rennie david Moher 钟丽丹郑颂华吴泰相李幼平商洪才张伯礼唐旭东吕爱平卞兆祥 SPIRIT中文工作組

临床研究方案是临床研究设计、实行、报告和评价的基础。然而，临床研究方案及现存的临床研究方案指引在内容和质量上差异很大。本文描述了《规范临床研究方案内容》（Standard Protocol Items：Recommendations for Interventional Tri... 详细信息

临床研究方案是临床研究设计、实行、报告和评价的基础。然而，临床研究方案及现存的临床研究方案指引在内容和质量上差异很大。本文描述了《规范临床研究方案内容》（Standard Protocol Items：Recommendations for Interventional Trials 2013 ）,简称SPIRIT2013声明，一个临床研究方案必须报告的条目指引的系统建立和范围。

关键词：临床研究条目标准