检索结果-南通市图书馆

Ten questions concerning future buildings beyond zero energy and carbon neutrality

在线全文

学校读者我要写书评

暂无评论

建筑节能 2017年第7期45卷 27-27页

作者： Na Wang Patrick E. Phelan Jorge G onzalez Chioke Harris G regor P. Henze Robert Hutchinson Jared Langevin Mary Ann Lazarus Brent Nelson Chris Pyke Kurt Roth david Rouse Karma sawyer stephen selkowitz 侯恩哲 <建筑节能>杂志社

Architects and planners have been at the forefront of envisioning a future built environment for millennia. How ever,fragmental view s that emphasize one facet of the built environment,such as energy,environment,or groundbreaking technologies,often do not achieve expected outcomes. Buildings are responsible for approximately one-third of w orldw ide carbon emissions and account for about 40% of primary energy consumption in the U. s. In addition to achieving the very ambitious goal of reducing building-associated greenhouse gas emissions by75% by 2050,buildings must improve their functionality and performance to meet current and future human,societal,and environmental needs in a changing w orld. In this article,w e introduce a new framew ork to guide potential evolution of the building stock in the next century,based on greenhouse gas emissions as the common thread to investigate the potential implications of new design paradigms,innovative operational strategies,and disruptive technologies. This framew ork emphasizes integration of multidisciplinary know ledge,scalability for mainstream buildings,and proactive approaches considering constraints and unknow *** framew ork integrates the interrelated aspects of the built environment through a series of quantitative metrics that aim to improve environmental outcomes w hile optimizing building performance to achieve healthy,adaptive,and productive buildings.

关键词：建筑节能建筑设计建筑风格建筑材料

Microarray-based screening of common pathophysiological processes in dilated cardiomyopathy and ischemic cardiomyopathy

在线全文

学校读者我要写书评

暂无评论

south China Journal of Cardiology 2019年第3期20卷 190-196,200页

作者： HE Yong-li LU Jian-jun FENG Zhe WANG Rui HUANG Cheng ZHOU Ying-ling Department of Cardiology Guangdong Cardiovascular Institute Guangdong Provincial People’s Hospital Guangdong Academy of Medical Sciences The second school of Clinical Medicine Southern Medical University Department of Medical services The First Affiliated Hospital of Sun Yat-sen University The First Affiliated Hospital of Henan University of science and Technology College of Clinical Medicine of Henan University of Science and Technology

Background Heart failure is the end stage of various heart diseases,which has different underlying mechanisms but somehow has similar features among different etiologies. Dilated cardiomyopathy(DCM) and ischemic cardiomyopathy(ICM)are two major subtypes. Unlike widely explored mechanisms on these heart diseases,their shared gene expression alterations in heart failure have been rarely investigated. Methods We first obtained genetic profiles of DCM and ICM as well as their non-failing(NF)control from two datasets in GEO database,GsE3585 and GsE1869. Comparing to NF,the differentially expressed genes(DEGs)of DCM and ICM were screened out and used for Gene Ontology(GO)analysis by david. The two sets of DEGs were compared and the overlap was selected out. Protein-protein interaction(PPI)network of the encoded proteins of shared DEGs was constructed and visualized via sTRING and Cytoscape respectively. Gene annotation interactions were analyzed using Bi NGO. The closely linked genes were sorted out as hub genes and accounted for common processes of DCM and ICM. Results There were 99 DEGs in DCM vs. NF,while 1317 DEGs in ICM vs. NF.29 DEGs were shared in two comparisons,which were mainly enriched in regulation of protein catabolic process,Golgi to endosome transport,protein targeting to Golgi,inactivation of MAPK activity,Golgi to plasma membrane protein transport,cytosol,and protein binding. There were 13 genes linked in the PPI network and thus they were selected as hub genes. Functions of these hub genes were mainly focused on energetic metabolism disorder,apoptosis and cardiac fibrosis. Conclusion Energetic metabolism disorder,apoptosis and cardiac fibrosis are likely the shared pathophysiological processes for dilated cardiomyopathy and ischemic cardiomyopathy.[s Chin J Cardiol 2019;20(3):190-197]

关键词： microarray bioinformatics dilated cardiomyopathy ischemic cardiomyopathy

Nature:研究利用单细胞分析阐明癌症干细胞在脑癌中的关键角色

在线全文

学校读者我要写书评

暂无评论

现代生物医学进展 2017年第6期17卷 I0003-I0003页

作者： Itay Tirosh, Andrew s. Venteicher, Christine Hebert, Leah E. Escalante, Keren Yizhak, Jonathan M. Fisher, Christopher Rodman, Mariella G. Filbin, Cyril Neftel, Jackson Nyman, Benjamin Izar, Joshua M. Francis, Kenneth J. Livak, Dave Gennert, Rahul satija, Todd R. Golub, Miguel N. Rivera, Gad Getz, Orit Rozenblatt-Rosen, Bradley E. Bernstein, Aviv Regev Mario L. suv agrave Andrew s. Venteicher, Christine Hebert, Leah E. Escalante, Keren Yizhak, Mariella G. Filbin, Cyril Neftel, Niyati Desai, Christina C. Luo, Aanand A. Patel, Maristela L. Onozato, Nicolo Riggi, Ravindra Mylvaganam, A. John Iafrate, Matthew P. Frosch, Miguel N. Rivera, Gad Getz, Bradley E. Bernstein, david N. Louis Mario L. suv agrave Andrew s. Venteicher, Anoop P. Patel, Brian V. Nahed, William T. Curry, Robert L. Martuza Daniel P. Cahill Christopher Mount Michelle Monje Mariella G. Filbin Todd R. Golub Joshua M. Francis Todd R. Golub Aviv Regev Broad Institute of Harvard and MIT Cambridge Massachusetts 02142 USA Department of Pathology and Center for Cancer Research Massachusetts General Hospital and Harvard Medical School Boston Massachusetts 02114 USA Department of Neurosurgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts 02114 USA Departments of Neurology Neurosurgery Pediatrics and Pathology Stanford University School of Medicine Stanford California 94305 USA Department of Pediatric Oncology Dana-Farber Cancer Institute and Children’s Hospital Cancer Center Boston Massachusetts 02215 USA Department of Medical Oncology Dana-Farber Cancer Institute Boston Massachusetts 02215 USA Howard Hughes Medical Institute Koch Institute Department of Biology MIT Cambridge Massachusetts 02139 USA

近日。来自麻省总医院、博德研究所及哈佛大学的研究人员通过联合研究，在单细胞水平上对脑瘤基因组进行了分析。他们发现。癌症干细胞或许能够诱发少突神经胶质瘤的发生，少突神经胶质瘤是一种缓慢发展但却非常难以治愈的脑癌，相关研... 详细信息

近日。来自麻省总医院、博德研究所及哈佛大学的研究人员通过联合研究，在单细胞水平上对脑瘤基因组进行了分析。他们发现。癌症干细胞或许能够诱发少突神经胶质瘤的发生，少突神经胶质瘤是一种缓慢发展但却非常难以治愈的脑癌，相关研究刊登于Nature杂志上。同时研究者还首次在人类脑瘤样本中鉴别出了癌症干细胞及其分化的后代细胞。

关键词：干细胞单细胞分析癌症脑瘤神经胶质瘤键角利用研究人员

改良的延迟钆增强MR成像在植入心脏除颤器病人中的应用

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2014年第2期 168-168页

作者： s.Rashid s.Rapacchi M Vaseghi R Tung K shivkumar J.P.Finn 张印 Radiological sciences David Geffen School of MedicineUniversity of California -Los Angeles 300 UCLA Medical Plaza Suite B119 Los Angeles CA 90095

目的提出并测试改良宽带的延迟钆增强(LGE)MR成像在去除植入心脏除颤器病人中高信号伪影的效果。材料与方法本研究经机构审查委员会批准并符合HIPAA

关键词：心脏除颤器宽带伪影心电除颤器 MR 病人

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

急性卒中影像学研究路径图Ⅱ

国际脑血管病杂志 2014年第2期22卷 81-92页

作者： Max Wintermark Gregory W. Albers Joseph P. Broderick Andrew M. Demchuk Jochen B. Fiebach Jens Fiehler James C. Grotta Gary Houser Tudor G. Jovin Kennedy R. Lees Michael H. Lev david s. Liebeskind Marie Luby Keith W. Muir Mark W. Parsons Rudiger von Kummer Joanna M. Wardlaw Ona Wu Albert J. Yoo Andrei V. Alexandrov Jeffry R. Alger Richard I. Aviv Roland Bammer Jean-Claude Baron Fernando Calamante Bruce C.V. Campbell Trevor C. Carpenter sφren Christensen William A. Copen Colin P. Derdeyn E. Clarke Haley Jr Pooja Khatri Kohsuke Kudo Maarten G. Lansberg Lawrence L. Latour Ting-Yim Lee Richard Leigh Weili Lin Patrick Lyden Grant Mair Bijoy IC Menon Patrik Michel Robert Mikulik Raul G. Nogueira Left φstergaard salvador Pedraza Christian H. Riedel Howard A. Rowley Pina C. sanelli Makoto sasaki Jeffrey L. saver Pamela W. schaefer Peter D. schellinger Georgios Tsivgoulis Lawrence R. Wechsler Philip M. White Greg Zaharchuk Osama O. Zaidat stephen M. Davis Geoffrey A. Donnan Anthony J. Furlan Werner Hacke Dong-Wha Kang Chelsea Kidw ell Vincent N. Thijs Gotz Thomalla steven J. Warach 严晓铭刘牧张晶晶柯开富不详南通大学附属医院神经内科 226001

卒中影像学研究组（strokeImagingResearchGroup，sTIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（stro... 详细信息

卒中影像学研究组（strokeImagingResearchGroup，sTIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（stroke Treatment Academy Industry Roundtable，sTAIR）期间举行。

关键词：急性卒中影像学神经放射学路径会议基金会学会美国

新近诊断的乳腺癌:对比增强能谱乳腺X线摄影与乳腺MRI评价病变范围的比较

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2018年第1期 90-90页

作者： s.A.Lee-Felker L.Tekchandani M.Thomas E.Gupta D.AndrewsTang A.Roth 张俊峰 Department of Radiological sciences David Geffen School of Medicine at UCLA

摘要目的以病理和影像随访作为参考标准,比较对比增强能谱乳腺摄影与乳腺MRI对新近诊断乳腺癌病人额外病灶检出的诊断价值。材料与方法本研究经机构伦理委员

关键词：对比增强 MRI 病变范围乳腺癌

非复杂下呼吸道感染的抗生素处方策略及不良结局：前瞻性咳嗽并发症队列（3C）研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

英国医学杂志中文版 2017年第12期20卷 681-681页

作者： Paul Little Beth stuart sue smith Matthew J Thompson Kyle Knox Annvanden Bruel Mark Lown Michael Moore david Mant 王雯王峰 University of southampton Primary Care Medical Group PCPS Unit Aldermoor Health Centre Southampton S0 16 5ST UK Nuffield Department of Primary Health Care sciences University of OxfordRadcliffe Observatory Quarter Oxford UK University of Washington Seattle WA USA 首都医科大学附属北京朝阳医院呼吸与危重症医学科

目的旨在评估16岁及以上的下呼吸道感染患者中，不同抗生素处方策略对不良结局的影响。

关键词：非复杂下呼吸道感染抗生素处方策略

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

乐高之家

城市环境设计 2019年第2期118卷 62-73页

作者： snorre Nash Andreas Klok Pedersen Agne Tamasauskaite Annette Birthe Jensen Ariel Joy Norback Wallner Ask Hvas Birgitte Villadsen Chris Falla Christoffer Gotfredsen Daruisz Duong Vu Hong david Zahle Esben Christoffersen Franck Fdida Ioana Fartadi scurtu Jakob Andreassen Jakob Ohm Laursen Jakob sand Jakub Matheus Wlodarczyk Jesper Bo Jensen Jesper Boye Andersen Julia Boromissza Kasper Reimer Hansen Katarzyna Krystyna siedlecka Katarzyna stachura Kekoa Charlot Leszek Czaja Lone Fenger Albrechtsen Louise B?geskov Hou Mads Enggaard stidsen Magnus Algreen suhr Manon Otto Marta Christensen Mathias Bank stigsen Michael Kepke Ole Dau Mortensen Ryohei Koike sergiu Calacean s?ren Askehave stefan Plugaru stefan Wolf Thomas Jakobsen Randb?ll Tobias Hjortdal Tommy Bj?rnstrup Iwan Baan Kim Christensen 陈思瑾

"乐高之屋展现了乐高积木的无限可能性。通过系统的创造力,让所有年龄段的孩子都能够使用这些工具来创造他们自己的世界,并通过游戏的方式生活其中。最棒的是,建筑和乐高游戏都是这样的:使人们能够想象比现状更令人兴奋和更具表现力的... 详细信息

"乐高之屋展现了乐高积木的无限可能性。通过系统的创造力,让所有年龄段的孩子都能够使用这些工具来创造他们自己的世界,并通过游戏的方式生活其中。最棒的是,建筑和乐高游戏都是这样的:使人们能够想象比现状更令人兴奋和更具表现力的新世界,并为他们提供使之成为现实的技能。这就是孩子们每天用乐高积木来做的事情,这也是我们今天用真实的砖石在乐高之屋里完成的事情,使比伦德向真

关键词：乐高积木展览空间

2021年IsHNE/HRs/EHRA/APHRs关于移动医疗心律失常管理共识:心脏节律专业人员的数字医疗工具

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国心脏起搏与心电生理杂志 2021年第2期35卷 95-104页

作者： Niraj Varma Iwona Cygankiewicz Mintu Turakhia Hein Heidbuchel Yufeng Hu Lin Yee Chen Jean-Philippe Couderc Edmond M.Cronin Jerry D.Estep Lars Grieten Deirdre A.Lane Reena Mehra Alex Page Rod Passman Jonathan Piccini Ewa Piotrowicz Ryszard Piotrowicz Pyotr G.Platonov Antonio Luiz Ribeiro Robert E.Rich Andrea M.Russo david slotwiner Jonathan s.steinberg Emma svennberg 蔡星星(翻译) 陈牧(翻译) 陈泰中(翻译) 费聿东(翻译) 费振涛(翻译) 龚畅祺(翻译) 胡晓亮(翻译) 李澄(翻译) 练小铭(翻译) 莫斌峰(翻译) 王海成(翻译) 王倩(翻译) 卫郅星(翻译) 徐全福(翻译) 杨眉(翻译) 杨钰粒(翻译) 于怡驰(翻译) 张睿(翻译) 赵铭哲(翻译) 赵晏(翻译) 李毅刚(审校) 王群山(审校) Cleveland Clinic ClevelandOHUSA Medical University of Lodz lodzPoland stanford University Palo AltoCAUSA Antwerp University and University Hospital AntwerpBelgium Taipei Veterans General Hospital TaipeiTaiwanChina University of Minnesota MinneapolisMNUSA University of Rochester RochesterNYUSA Temple University PhiladelphiaPAUSA Hasselt University HasseltBelgium University of Liverpool LiverpoolUK Northwestern University Feinberg school of Medicine Chicagot ILUSA Duke University DurhamNCUSA National Institute of Cardiology WarsawPoland Lund University LundSweden Faculdade de Medicina Centro de TelessaúdeHospital and Clínicasand Departamento de Clínica MédicaUniversidade Federal de Minas GeraisBelo HorizonteBrazil Cooper Medical school of Rowan University CamdenNJUSA Cardiology Division New York-PresbyterianQueensand School of Health Policy and ResearchWeill Cornell MedicineNew YorkNYUSA Karolinska University Hospital StockholmSweden 上海交通大学医学院附属新华医院心内科上海交通大学心律失常诊治中心

国际动态心电图和无创心电图学会/心律学会/欧洲心律协会/亚太心律协会制定的"关于移动医疗心律失常管理共识"描述了移动医疗(mHealth)技术在心律失常管理中的现状,涉及数字医疗工具范围,以及可能应用于心律失常的诊断和协助临床决策。... 详细信息

国际动态心电图和无创心电图学会/心律学会/欧洲心律协会/亚太心律协会制定的"关于移动医疗心律失常管理共识"描述了移动医疗(mHealth)技术在心律失常管理中的现状,涉及数字医疗工具范围,以及可能应用于心律失常的诊断和协助临床决策。合并症和生活方式管理(日益公认在心律失常中起作用)以及患者自我管理赋予了mHealth新的内容。共识对预测分析的承诺,以及嵌入了mHealth的常规临床关怀的操作面临的挑战,进行了探讨。

关键词：心血管病学移动医疗综述心律失常心脏节律