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多巴胺D_2受体基因启动子多态性与帕金森病的关联研究

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中华医学遗传学杂志 2002年第6期19卷 524-525页

作者：彭蓉苟婴如袁强李涛袁光固罗德儒刘协和 david a.collier 四川大学华西医院神经内科成都610041 MolecularGeneticLab InstituteofPsychiatry 四川大学华西医院心理卫生研究所成都610041

目的　探讨中国汉族人群多巴胺 D2 受体基因启动子多态性在帕金森病 (Parkinson'sdisease,PD)遗传易感性中的作用。方法　采用病例 -对照关联分析、聚合酶链反应 -限制性片段长度多态性方法分析了 12 3例 PD患者 (PD组 )与 12 4名健康成... 详细信息

目的　探讨中国汉族人群多巴胺 D2 受体基因启动子多态性在帕金森病 (Parkinson'sdisease,PD)遗传易感性中的作用。方法　采用病例 -对照关联分析、聚合酶链反应 -限制性片段长度多态性方法分析了 12 3例 PD患者 (PD组 )与 12 4名健康成人 (对照组 )多巴胺 D2 受体基因启动子多态性。结果　 PD组 - 141△ C等位基因频率为 8.5 % ,对照组为 11.7% ,两组差异无显著性 (P>0 .0 5 ) ;中国汉族人PD组和对照组 - 141△ C等位基因频率明显高于意大利南部人群 ,差异有显著性 (P<0 .0 5 )。结论　中国汉族人群多巴胺 D2 受体基因启动子多态性与 PD的遗传易感性无关 ,该多态性有明显的种族差异。

关键词：帕金森病多巴胺D2受体基因多态性

中国人群中家族性精神分裂症与1号染色体的连锁分析

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中华医学遗传学杂志 2002年第6期19卷 491-494页

作者：蔡贵庆伍新尧李涛 david a.collier 刘协和冯炳建邓红童大跃李建金区敬华中山大学中山医学院法医学系广州510080 DepartmentofPsychologicalMedicine 四川大学华西医院心理卫生研究所中山大学中山医学院肿瘤研究所广州510080

目的　探讨中国人群中家族性精神分裂症易感基因与 1号染色体的分子遗传学关系。方法用基因组扫描的方法 ,选择了平均分布在 1号染色体上的 2 9个标记 ,对 32个家族性精神分裂症家系样本进行易感基因扫描。结果　参数连锁分析结果 ,在... 详细信息

目的　探讨中国人群中家族性精神分裂症易感基因与 1号染色体的分子遗传学关系。方法用基因组扫描的方法 ,选择了平均分布在 1号染色体上的 2 9个标记 ,对 32个家族性精神分裂症家系样本进行易感基因扫描。结果　参数连锁分析结果 ,在隐性模型下 ,多点连锁在 2 6 2 .5 2 c M位置得到最大异质性 L od分为 1.70 ;非参数连锁分析结果 ,2 6 2 .5 2 c M位置处得到最大的多点非参数连锁分为 1.71(P=0 .0 46 ) ,其次是 149.70 c M位置处得到多点非参数连锁分为 1.37(P=0 .0 86 ) ,分别对应于标记 D1S2 0 6、D1S42 5位点的位置。结论　进一步支持在染色体 1q上可能存在家族性精神分裂症的易感基因。

关键词：中国人群连锁分析精神分裂症易感基因 1号染色体

Managing obsolescence of embedded hardware and software in secure and trusted systems

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Frontiers of Engineering Management 2020年第2期7卷 172-181页

作者： Zachary a.collier James H.LAMBERT collier Research Systems BarboursvilleVA 22923USA Department of Engineering Systems and Environment University of VirginiaCharlottesvilleVA 22903USA

Obsolescence of integrated systems which contain hardware and software is a problem that affects multiple industries and can occur for many reasons,including technological,economic,organizational,and social *** is especially acute in products and systems that have long life cycles,where a high rate of technological innovation of the subcomponents result in a mismatch in life cycles between the components and the *** several approaches for obsolescence forecasting exist,they often require data that may not be *** paper describes an approach using non-probabilistic scenarios coupled with decision analysis to investigate how particular scenarios influence priority setting for products and *** are generated from a list of emergent and future conditions related to *** key result is an identification of the most and least disruptive scenarios to the decision maker’s *** example is presented related to the selection of technologies for energy islanding,which demonstrates the methodology using six obsolescence *** paper should be of broad interest to scholars and practitioners engaged with enterprise risk management and similar challenges of large-scale systems.

关键词： enterprise risk management diminishing manufacturing sources and material shortages Scenariobased preferences systems engineering deep uncertainty product life cycle

Identifying potential evolutionary relationships within a facultative lycaenid-ant system： Ant association, oviposition, and butterfly-ant conflict

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Insect Science 2007年第5期14卷 401-409页

作者： NElL collier School of Biological Sciences Hinders University of South Australia Adelaide South Australia Australia

Facultative associations are commonly encountered between ants and lycaenids, although the nature and patterns of associations are typically unclear. This study investigated a facultative symbiosis involving the lycaenid Theclinesthes albocincta （Lycaenidae）, its host plant Adriana quadripartita and Australian native ants. Ants in the genera Ochetellus and Iridomyrmex were most frequently found in association with T. albocincta larvae, although Iridomyrmex ants were found in much lower abundance than were ants in Ochetellus. The abundances of Ochetellus and Iridomyrmex were highly correlated with larval abundance, but not egg abundance. Observations and experiments recorded oviposi- tion on male inflorescences on more than 95% of occasions, but oviposition was not greater on inflorescences with ants present. Behavioral assays showed that Iridomyrmex ants were aggressive towards female butterflies on significantly more occasions than were Ochetellus ants. These findings indicate potential evolutionary relationships between T. albocincta and two genera of ants that were abundant within the habitat.

关键词： Dolichoderinae euphorbiaceae interactions tritrophic

使用常规测井方法识别高孔隙度低渗透率砂岩储集层的典型实例

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石油物探译丛 1993年第6期 66-82页

作者： Hughbert a.collier 金康辰

陆上中型砂岩有良好孔隙度(15—20%),并不总是有良好的渗透率(几十～几百 md)。由于取芯很少,许多储集层的潜在产能特性主要是借助于电缆测井资料。但低渗透率的测井响应不显著,易被忽略,以致于不能识别低渗透率层而导致测井解释的失误... 详细信息

陆上中型砂岩有良好孔隙度(15—20%),并不总是有良好的渗透率(几十～几百 md)。由于取芯很少,许多储集层的潜在产能特性主要是借助于电缆测井资料。但低渗透率的测井响应不显著,易被忽略,以致于不能识别低渗透率层而导致测井解释的失误。综合测井资料和岩芯资料,能有效地修正储集层模型。仔细分析裸眼井测井图,尤其在取得一些边界井的岩芯资料时,就能识别低渗透层,并大大改善对储采层特性的描述。

关键词：孔隙度渗透率储集层砂岩油气田

Recurrent lymphoma presenting as painless, chronic intussusception: A case report

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World Journal of Clinical Cases 2020年第2期8卷 306-312页

作者： Parker Giroux Anderson collier Michael Nowicki Department of Pediatrics University of Mississippi Medical CenterJacksonMS 39216United States Division of Pediatric Hematology and Oncology University of Mississippi Medical CenterJacksonMS 39216United States Division of Pediatric Gastroenterology University of Mississippi Medical CenterJacksonMS 39216United States

BACKGROUND The clinical presentation of acute lymphoblastic lymphoma is highly *** prognosis is good, recurrence of disease can occur. Gastrointestinal relapse, including intussusception, is well-described but the absence of abdominal pain in this setting is *** SUMMARY We report a 13-year-old male with B-cell precursor acute lymphoblastic leukemia in remission presenting with anemia and weight loss. Examination was significant for absence of abdominal pain, but a stool sample was positive for occult blood. Pan-endoscopy was performed with colonoscopy revealing a mass filling the colonic lumen. Biopsy of the mass confirmed recurrence of recurrent Bcell lymphoma. Computed tomography scan revealed ileocolic intussusception resulting from the tumor. This case is unusual in that the patient had no abdominal pain despite the presence of *** While intestinal involvement with lymphoma has been well described in the literature, presentation as painless intussusception has not been reported. This case report highlights the wide spectrum of clinical manifestations of recurrent Bcell lymphoma involving the gastrointestinal tract, in particular the near absence of symptoms despite the finding of intussusception.

关键词： B-cell acute lymphoblastic leukemia Tumor relapse Intussusception Case report Anemia

Secure Video Streaming with Lightweight Cipher PRESENT in an SDN Testbed

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Computers, Materials & Continua 2018年第12期57卷 353-363页

作者： Pengcheng Liu Xiaojun Wang S.R.Chaudhry Khalid Javeed Yue Ma Martin collier School of Electrical and Computer Engineering Dublin City UniversityDublinIreland. Department of Computer Engineering Bahria UniversityIslamabadPakistan School of Computer Science Beijing University of Posts and TelecommunicationsBeijing100876China

The combination of traditional processors and Field Programmable Gate Arrays(FPGA)is shaping the future networking platform for intensive computation in resource-constrained networks and *** networks present two key challenges of security and resource *** ciphers are suitable to provide data security in such constrained *** the lightweight PRESENT encryption algorithm in a reconfigurable platform(FPGAs)can offer secure communication service and *** paper presents hardware acceleration of security primitives in SDN using *** implement an efficient design of the PRESENT algorithm for faster,smaller and lower power consumption hardware circuit using *** evaluate the performance of the hardware and software implementations of *** results prove that the proposed hardware design is a viable option for use in resource constrained devices in future networks and their applications.

关键词： Lightweight cipher netFPGA openFlow RESENT encryption

Operations Management: Integrated Goods and Services Approach WITH Student CD-Rom AND Microsoft Project

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A Programmable Timing System for Debating Training and Competitions

2007年

作者： James R Evans david collier

来源：畅想之星图书光盘版（南... 评论

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Journal of Measurement Science and Instrumentation 2010年第S1期1卷 101-103,106页

作者： Michael collier Pamela.collier College of Information and Electrical Engineering Shandong University of Science & Technology Qingdao 266510 College of Foreign Languages Shandong University of Science and Technology Qingdao266510China

A piece of equipment designed under a multi-disciplinary project in Shandong University of Science and Technology is *** purpose is to indicate speech-time status to speakers in debates by presenting a three-light output The speech length may be programmed by the user with a combination of buttons and LCD *** system is portable and microcontroller-based,using on-chip timers for accurate measurement of durations.

关键词： oral linguistic debating microcontroller timing