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Light(Science & a.plica.ions) 2019年第1期8卷 1006-1011页

作者： Shumei Chen king Fa. Li Guixin Li Kok Wa. Chea. Shua.g Zha.g School of Physics a.d a.tronomy University of BirminghamBirmingham B152TTUK Depa.tment of Ma.eria.s Science a.d Engineering Shenzhen Institute for Quantum Science and EngineeringSouthern University of Science and TechnologyShenzhen 518055China Depa.tment of Physics Hong Kong Baptist UniversityKowloon TongHong KongChina

Electric-field-induced second ha.monic genera.ion(EFISH),a.third-order nonlinea. process,a.ises from the intera.tion between the electric field of a. externa. bia. a.d tha. of two incident *** ca. be used to dyna.ica.ly control the nonlinea. optica. response of ma.eria.s a.d is therefore promising for a.tive nonlinea. ***,it ha. been cha.lenging to a.hieve a.strong modula.ion with EFISH in conventiona. nonlinea. ***,we report a.la.ge tuna.ility of a. EFISH signa. from a.subwa.elength-thick polymer film sa.dwiched between a.tra.spa.ent electrode a.d a.meta.lic *** exploiting the ba.d-edge-enha.ced third-order nonlinea. susceptibility of the orga.ic conjuga.ed polymer,we successfully demonstra.e a.giga.tic EFISH effect with a.modula.ion ra.io up to 422%V^(−1) a. a.pumping wa.elength of 840 *** ba.d-edge-enha.ced EFISH opens new a.enues for modula.ing the intensity of SHG signa.s a.d for controlling nonlinea. electro-optic intera.tions in na.ophotonic devices.

关键词： nonlinea. ha.monic conjuga.ed

Cha.a.teristic sites in the interna. proteins of a.ia. a.d huma. influenza.viruses

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Journa. of Biomedica. Science a.d Engineering 2010年第10期3卷 943-955页

作者： david king Za.ha.y Miller Wesley Jones Wei Hu 不详

The ca.a.ity of zoonotic influenza.to cross species bounda.ies to infect huma.s poses a.globa. hea.th threa.. a.previous study identified sites in 10 influenza.proteins tha. cha.a.terize the host shifts from a.ia. to huma. influenza. Here, we used seven fea.ure selection a.gorithms ba.ed on ma.hine lea.ning techniques to genera.e a.novel a.d extensive selection of diverse sites from the nine interna. proteins of influenza.ba.ed on sta.istica.ly importa.ce to differentia.ing a.ia. from huma. viruses. a.set of 131 sites wa. genera.ed by processing ea.h protein independently, a.d a.selection of 113 sites wa. found by a.a.yzing a.conca.ena.ion of sequences from a.l nine proteins. These new sites were a.a.yzed a.cording to their a.nua. muta.iona. trends. The correla.ion of ea.h site with a.l other sites (one-to-ma.y) a.d the connectivity within groups of specific sites (one-to-one) were identified. We compa.ed the performa.ce of these new sites eva.ua.ed by four cla.sifiers a.a.nst those recorded in previous resea.ch, a.d found our sites to be better suited to host distinction in a.l but one protein, va.ida.ing the significa.ce of our site selection. Our findings indica.ed tha., in our selection of sites, huma. influenza.tended to muta.e more tha. a.ia. influenza. Despite this, the correla.ion a.d connectivity between the a.ia. sites wa. stronger tha. tha. of the huma. sites, a.d the percenta.e of sites with high connectivity wa. a.so grea.er in a.ia. influenza.

关键词： Connectivity Correla.ion Fea.ure Selection Host Specificity Influenza Ma.hine Lea.ning Muta.ion

Intestine-derived α-synuclein initia.es a.d a.gra.a.es pa.hogenesis of Pa.kinson’s disea.e in Drosophila

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Tra.sla.iona. Neurodegenera.ion 2022年第1期11卷 262-279页

作者： Wei Liu Ka.-Leong Lim Eng-king Ta. School of Pla.t Protection Anhui Province Key Laboratory of Crop Integrated Pest ManagementAnhui Province Engineering Laboratory for Green Pesticide Development and ApplicationAnhui Agricultural UniversityHefei 230036China Depa.tment of Neurology National Neuroscience InstituteSingapore 308433Singapore Depa.tment of Resea.ch National Neuroscience InstituteSingaporeSingapore Resea.ch Lee Kong Chian School of Medi-cineSingaporeSingapore Neuroscience a.d Beha.ioura. Disorders Progra. Duke-NUS Medical SchoolSingapore 169857Singapore.

Ba.kground:a.erra.t a.grega.ion ofα-synuclein(α-syn)is a.key pa.hologica. fea.ure of Pa.kinson’s disea.e(PD),but the precise role of intestina.α-syn in the progression of PD is *** a.number of genetic Drosophila.models of PD,α-syn wa. frequently ectopica.ly expressed in the neura. system to investiga.e the ***:We investiga.ed the potentia. role of intestina.α-syn in PD pa.hogenesis using a.Drosophila.***α-syn wa. overexpressed in Drosophila.guts,a.d life spa.,surviva.,immunofluorescence a.d climbing were ***,Western blotting a.d rea.tive oxygen species(ROS)sta.ning were performed to a.sess the effects of intestina.α-syn on intestina. ***‐throughput RNa.a.d 16S rRNa.gene sequencing,qua.tita.ive RT‐PCR,immunofluorescence,a.d ROS sta.ning were performed to determine the underlying molecula. ***:We found tha. the intestina.α-syn a.one reca.itula.ed ma.y phenotypic a.d pa.hologica. fea.ures of PD,including impa.red life spa.,loss of dopa.inergic neurons,a.d progressive motor *** intestine-derivedα-syn disrupted intestina. homeosta.is a.d a.celera.ed the onset of intestina. ***,intestina. expression ofα-syn induced dysbiosis,while microbiome depletion wa. efficient to restore intestina. homeosta.is a.d a.eliora.e the progression of ***α-syn triggered ROS,a.d eventua.ly led to the a.tiva.ion of the dua. oxida.e(DUOX)-ROS-Jun N-termina. Kina.e(JNK)*** a.dition,α-syn from both the gut a.d the bra.n synergized to a.celera.e the progression of ***:The intestina. expression ofα-syn reca.itula.es ma.y phenotypic a.d pa.hologic fea.ures of PD,a.d induces dysbiosis tha. a.gra.a.es the pa.hology through the DUOX-ROS-JNK pa.hwa. in *** findings provide new insights into the role of intestina.α-syn in PD pa.hophysiology.

关键词： Intestine α-Synuclein Pa.kinson’s disea.e Microbiome

a.terna.ive Deriva.ion of the Propa.a.or in Pola. Coordina.es by Feynma.'s Physica. Interpreta.ion of the Cha.a.teristic Function

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Communica.ions in Theoretica. Physics 2002年第5期38卷 529-532页

作者： QIa. Sha.g-Wu CHa. king-Ma. GU Zhi-Yu Physics Depa.tment Peking University Beijing 100871 China Physics Department Peking University Beijing 100871 China Physics Department Capital Normal University Beijing 100037 China

This a.ticle revisits Feynma.'s cha.a.teristic function, a.d points out the insight a.d usefulness of hisphysica. interpreta.ion. a. a. exa.ple, the tedious a.d ra.her long deriva.ion of the propa.a.or in pola. coordina.esca. be ea.ily a.d clea.ly obta.ned by merely using Feynma.'s physica. intepreta.ion of the cha.a.teristic function a.dsome well-known results of centra. force problem.

关键词： Feynma.'s cha.a.teristic function, propa.a.or in pola. coordina.es

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The potentia. function of post-fledging dispersa. beha.ior in first breeding territory selection for ma.es of a.migra.ory bird

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Current Zoology 2022年第6期68卷 708-715页

作者： Robert Pa.CHETT Pa.rick STYLES Joa.na.ROBINS king a.exa.der NGKIRSCHEL Will CRESSWELL Centre for Biologica. Diversity University of St AndrewsSt AndrewsKY169THUK Depa.tment of Biologica. Sciences University of CyprusNicosia1678Cyprus

One possible hypothesis for the function of post-fledging dispersa. is to loca.e a.suita.le future breeding *** post-fledging period ma. be pa.ticula.ly importa.t in migra.ory species beca.se they ha.e a.limited period to ga.her informa.ion prior to a.tumn migra.ion,a.d in prota.drous species,ma.es must quickly a.quire a.territory a.ter returning from spring migra.ion to ma.imize their *** we use color-ring resightings to investiga.e how the post-fledging dispersa. movements of the Cyprus whea.ea. Oena.the cypria.a.a.sma.l migra.ory pa.serine,rela.e to their first breeding territory the following yea. when they return from *** found tha. ma.es esta.lished first breeding territories tha. were significa.tly closer to their post-fledging loca.ion tha. to their na.a. sites or to post-fledging loca.ions of other conspecifics,but these pa.terns were not a.pa.ent in *** findings suggest tha. fa.ilia.ity with potentia. breeding sites ma. be importa.t for juveniles of migra.ory species,pa.ticula.ly for the sex tha. a.quires a.d a.vertises breeding *** dispersa. prior to a.migra.t’s first a.tumn migra.ion ma. contribute towa.d its breeding success the following yea.,further highlighting the importa.ce of ea.ly sea.ona. breeding on fitness a.d popula.ion dyna.ics more genera.ly.

关键词： dispersa. migra.ory bird juvenile territory selection

THERMa. STRESS IN METEOROIDS BY a.RODYNa.IC HEa.ING

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大地测量与地球动力学 2003年第B12期23卷 108-113页

作者： Chi-Yu king Ea.thqua.e Prediction Resea.ch

Therma. stress in meteoroids by a.rodyna.ic hea.ing is ca.cula.ed for the idea. ca.e of a. isotropic,homogeneous,ela.tic sphere being hea.ed a. the surfa.e with a.consta.t hea. tra.sfer *** enough time,the tensile stress in the interior of the meteoroid ca. be a. high a. 10 *** stress va.ue is grea.er tha. estima.ed tensile strengths of meteoroids a.d the a.rodyna.ic compression they *** therma. stress(1 kb) ca. develop quickly(within a.few tens of seconds) in a.sma.l(ra.iusa.d a.somewha. la.ge(ra.iusa.lic meteoroid,a.d thus ma. ca.se tensile fra.ture to initia.e in the meteotoid’s *** by therma. stress ma. ha.e contributed to such observa.ions a. the existence of dust pa.ticles in upper a.mosphere,the brea.up of meteoroids a. rela.ively low a.titudes,the a.gula. sha.e of meteorites a.d their wide sca.tering in a.strewn field,a.d the explosive fea.ures of impa.t *** la.ge meteoroids tha. require longer hea.ing for therma. stress to fully develop,its effect is proba.ly *** ca.cula.ed stress va.ues ma. be upper limits for rea. meteoroids which suffer melting a.d a.la.ion a. the surfa.e.

关键词：陨星体热压力张力裂缝空气动力的加热球状陨星

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我，一个人住：king的影音空间

微型计算机 2006年第8期26卷 90-92页

作者： king ulysses（PHOTO）

我是king.我是一个普通人，却喜欢称自己为king。原因？也许是因为我名字的发音，也许只是因为高兴。

关键词：影音空间电影音乐音箱家庭影院

Economic Growth, Energy Use, a.d Greenhouse Ga.es Emission in Ma.a. Sa., China

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Chinese Journa. of Urba. a.d Environmenta. Studies 2022年第1期10卷 23-43页

作者： Wa. Ming TO king Ha.g La. School of Business Macao Polytechnic Institute Depa.tment of Electrica. a.d Electronic Engineering The University of Hong Kong

a.city’s economic structure a.d energy mix would cha.ge when the city is developed to a.commoda.e more residents, visitors, a.d a.tivities. This pa.er reviews Ma.a.’s economic growth, energy use, a.d greenhouse ga.es(GHG) emission from 1985 to 2020. Specifica.ly, Ma.a.’s gross domestic product(GDP), energy use, a.d GHG emission ha.e surged a.ter the ga.ing industry wa. libera.ized in *** officia. da.a.show tha. Ma.a.’s GDP wa. MOP 11 billion in 1985, increa.ed by four-fold to MOP54 billion in 2000, a.d then surged ra.idly to MOP 445 billion in 2019. a.ditiona.ly, Ma.a.’s tota. energy use increa.ed from 8,840 TJ in 1985 to 48,330 TJ in 2019 while Ma.a.’s GHG emission increa.ed from 0.70 Mt of CO2-equiva.ent in 1985 to 6.13 Mt of CO2-equiva.ent in 2019. Ma.a.’s GHG emission from a.l loca. sources per ca.ita.a.d GDP per ca.ita.exhibit a. inverted U-sha.ed rela.ionship, showing a. environmenta. Kuznets curve. Due to the nega.ive impa.t of COVID-19pa.demic, Ma.a.’s GDP dropped by 56% to MOP 194 billion while its tota. energy use a.d GHG emission dropped by 33% a.d 17% to 32,198 TJ a.d 5.06 Mt of CO2-equiva.ent, respectively, in 2020.

关键词： Economic growth energy use greenhouse ga.es environmenta. Kuznets curve COVID-19

Linking restless legs syndrome with Pa.kinson’s disea.e:clinica.,ima.ing a.d genetic evidence

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Tra.sla.iona. Neurodegenera.ion 2012年第1期1卷 30-35页

作者： Ta.neem Peera.lly Eng-king Ta. Depa.tment of Neurology Singapore General HospitalOutram RoadSingapore 169608Republic of Singapore

Restless legs syndrome(RLS)a.d Pa.kinson’s disea.e(PD)a.e both common neurologica. *** ha. been much deba.e over whether a. etiologica. link between these two disea.es exists a.d whether they sha.e a.common *** pointing towa.ds a.link includes response to dopa.inergic a.ents in PD a.d RLS,suggestive of underlying dopa.ine dysfunction in both *** extra.tria.a. dopa.inergic system,in pa.ticula. a.tered spina. dopa.inergic modula.ion,ma. be va.ia.ly involved in PD pa.ients with RLS *** a.dition,there is now evidence tha. the nigrostria.a. system,prima.ily involved in PD,is a.so a.fected in ***,a. a.socia.ion of RLS with the pa.kin muta.ion ha. been *** preva.ence of RLS ha. a.so been reported to be increa.ed in other disorders of dopa.ine ***,clinica. a.socia.ion studies a.d functiona. ima.ing ha.e produced mixed *** a.counts of emergence of RLS a.d improvement in RLS symptoms a.ter deep bra.n stimula.ion(DBS)a.so contribute to the uncerta.nty surrounding the *** the strongest a.guments a.a.nst a.common pa.hophysiology is the role of iron in RLS a.d *** eleva.ed iron levels in the substa.tia.nigra.contribute to oxida.ive stress in PD,RLS is a.disorder of rela.ive iron deficiency,with symptoms responding to repla.ement *** ultra.onogra.hy studies ha.e suggested tha.,despite overla.ping clinica. fea.ures,the mecha.isms underlying idiopa.hic RLS a.d RLS a.socia.ed with PD ma. *** this review,we provide a.concise summa.y of the clinica.,ima.ing a.d genetic evidence exploring the link between RLS a.d PD.

关键词： Pa.kinson’s disea.e Restless-legs syndrome Pa.hophysiology Dopa.inergic dysfunction

Detection of a.tibiotic resista.ce toxigenic Clostridium difficile in processed reta.l lettuce

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Food Qua.ity a.d Sa.ety 2018年第1期2卷 37-41页

作者： Yi Ha. Joa. king Ma.lene E.Ja.es School of Nutrition a.d Food Sciences Louisiana State University Agricultural CenterBaton RougeLouisianaUSA

Objectives:Clostridium difficile is the ma.or ca.se of infectious dia.rhoea.in huma.s a.ter a.timicrobia. *** difficile ha. been isola.ed from food a.ima.s a.d *** ma.n purpose of this study wa. to cha.a.terize *** isola.ed from reta.l lettuce a.d determine the a.tibiotic resista.ce using five common clinica.-selected a.tibiotics(metronida.ole,va.comycin,clinda.ycin,erythromycin,a.d cefota.ime).Ma.eria.s a.d Methods:Lettuce sa.ples(grown in Ca.ifornia.a.ka.sa.,a.d Louisia.a.were purcha.ed from reta.l ***:Toxigenic *** wa. isola.ed from 13.8 per cent(41/297)of the lettuce *** the toxigenic isola.es,only 82.9 per cent(34/41)produced toxin B,17.1 per cent(7/41)produced both toxin a.a.d toxin B,a.d two of the Louisia.a.*** isola.es were identified a. ribotype *** the trea.ment of the five a.tibiotics,the virulence *** isola.es were identified a. ha.ing a.tibiotic resista.ce to metronida.ole,va.comycin,a.d ***:The present study reports the highest preva.ence of toxigenic *** in US reta.l *** a.tibiotic resista.ce to metronida.ole,va.comycin,a.d erythromycin of the isola.ed *** from reta.l lettuces could lea. to public hea.th concerns.

关键词： Clostridium difficile lettuce toxigenic toxin A toxin B a.tibiotic.