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Recurrence Quantification Analysis of Rough Surfaces Applied to Optical and Speckle Profiles

作者： (英)达尔文(Charles Robert darwin)

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Journal of Applied Mathematics and Physics 2016年第4期4卷 720-732页

作者： Oscar Sarmiento Martinez darwin Mayorga Cruz Jorge Uruchurtu Chavarín Estela Sarmiento Bustos Technological Institute of Zacatepec-ITZ Metal Mechanical Department Electromechanical Engineering Calzada Tecnológico Zacatepec Mexico Center for Research in Engineering and Applied Sciences-CIICAp Av. Universidad Chamilpa Cuernavaca Mexico Emiliano Zapata Technological University-UTEZ Industrial Mechanics Area Av. Universidad Tecnológica Col. Palo Escrito Emiliano Zapata Mexico

In this paper, Recurrence Quantification Analysis (RQA) is set as a practical nonlinear data tool to establish and compare surface roughness (Ra) through percentage parameters of a dynamical system: Recurrence (%REC), Determinism (%DET) and Laminarity (%LAM). Variations in surface roughness of different machining procedures from a typical metallic casting comparator are obtained from scattering intensity of a laser beam and expressed as changes in the statistics of speckle patterns and profiles optical properties. The application of the analysis (RQA) by Recurrence Plots (RPs), allowed to distinguish between machining procedures, highlighting features that other methods are unable to detect.

关键词： RQA Recurrence Plots Roughness Optical Data Processing Speckle Patterns

Confocal endomicroscopy and cyst fluid molecular analysis: Comprehensive evaluation of pancreatic cysts

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World Journal of Gastrointestinal Endoscopy 2018年第1期10卷 1-9页

作者： Feng Li Ahmad Malli Zobeida Cruz-Monserrate darwin L Conwell Somashekar G Krishna Division of Gastroenterology Hepatology and Nutrition Ohio State University Wexner Medical Center

Increases in the quality as well as utilization of cross-sectional imaging have led to rising diagnoses of pancreatic cystic lesions(PCL). Accurate presurgical diagnosis enables appropriate triage of PCLs. Unfortunately, current diagnostic approaches have suboptimal accuracy and may lead to unnecessary surgical resections or missed diagnoses of advanced neoplasia. Additionally, early detection represents an opportunity for intervention to prevent the progression to pancreatic adenocarcinoma. Our aim for this review is to systematically review the current literature on confocal endomicroscopy and molecular biomarkers in the evaluation of PCLs. Confocal laser endomicroscopy is a novel technology that allows for real-time in vivo microscopic imaging with multiple clinical trials identifying characteristic endomicroscopy findings of various pancreatic cystic lesions. DNA-based molecular markers have also emerged as another diagnostic modality as the pattern of genetic alternations present in cyst fluid can provide both diagnostic and prognostic data. We propose that both techniques can be utilized to improve patient outcomes.

关键词： Pancreas Pancreatic cyst Pancreatic adenocarcinoma Confocal endomicroscopy Next generation sequencing Molecular marker

Partial characterization of the N-linked oligosaccharide structures on P-selectin glycoprotein ligand-1 (PSGL-1)

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Cell Research 2001年第1期11卷 28-36页

作者： AEED PAUL A, JIAN GUO GENG, darwin ASA, LORETTA RAYCROFT, LI MA, KE P ELHAMMER (Pharmacia Corp., 7000 Portage Road, Kalamazoo, MI 49001-0199, USA) (Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy o 1Pharmacia Corp. 7000 Portage Road Kalamazoo MI 49001-0199 USA 2Institute of Biochemistry and Cell Biology Shanghai Institute for Biological Sciences Chinese Academy of Sciences 320 Yueyang Road Shanghai 200031 China 1Pharmacia Corp. 7000 Portage Road Kalamazoo MI 49001-0199 USA 1Pharmacia Corp. 7000 Portage Road Kalamazoo MI 49001-0199 USA 1Pharmacia Corp. 7000 Portage Road Kalamazoo MI 49001-0199 USA 1Pharmacia Corp. 7000 Portage Road Kalamazoo MI 49001-0199 USA

PSGL-1, a specific ligand for P-, E- and L-selectin, was isolated from in vivo [3H]-glucosamine labeled HL- 60 cells by a combination of wheat germ agglutinin-agarose and P- or E-selectin-agarose chromatography. N- linked oligosaccharides were released from the purified, denatured ligand molecule by peptide: N-glycosidase F treatment and, following separation by Sephacryl S-200 chromatography, partially characterized using lectin, ion-exchange and size-exclusion chromatography in combination with glycosidase digestions. The data obtained suggest that the N-glycans on PSGL-1 are predominantly core-fucosylated, multiatennary complex type structures with extended, poly- N- acetyllactosamine contaniing outer chains. A portion of the outer chains appears to be substituted with fucose indicating that the N-glycans, in addition to the O-glycans on PSGL-1, may be involved in selectin binding.

关键词： Selectin ligands PSGL-1 N-glycans

Intraoperative endoscopic retrograde cholangiopancreatography for traumatic pancreatic ductal injuries:Two case reports

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作者：达尔文(C. darwin)

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World Journal of Gastrointestinal Endoscopy 2022年第5期14卷 342-350页

作者： Andrew Canakis Varun Kesar Caleb Hudspath Raymond E Kim Thomas M Scalea Peter darwin Division of Gastroenterology and Hepatology University of Maryland School of MedicineBaltimoreMD 21201United States Department of Surgery R.Adams Cowley Shock Trauma CenterUniversity of Maryland School of MedicineBaltimoreMD 21201United States

BACKGROUND In order to successfully manage traumatic pancreatic duct(PD)leaks,early diagnosis and operative management is paramount in reducing morbidity and *** the acute setting,endoscopic retrograde cholangiopancreatography(ERCP)can be a useful,adjunctive modality during exploratory *** with sphincterotomy and stent placement improves preferential drainage in the setting of injury,allowing the pancreatic leak to properly ***,data in this acute setting is *** SUMMARY In this case series,a 27-year-old male and 16-year-old female presented with PD leaks secondary to a gunshot wound and blunt abdominal trauma,*** underwent intraoperative ERCP within an average of 5.9 h from time of presentation.A sphincterotomy and plastic pancreatic stent placement was performed with a 100%technical and clinical *** were no associated immediate or long-term *** discharge,both patients underwent repeat ERCP for stent removal with resolution of ductal *** These experiences further demonstrated that widespread adaption and optimal timing of ERCP may improve outcomes in trauma centers.

关键词： Pancreatic ductal injury Pancreatic leaks Endoscopic retrograde cholangiopancreatography Trauma Endoscopic stenting Case report