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The use of 5-fluorouracil in the prevention of tendon adhesions: A systematic review

Animal Models and Experimental Medicine 2020年第1期3卷 87-92页

作者： Omid Nazifi Andrew LStuart dariush nikkhah Royal Perth Hospital PerthWAAustralia Locum Consultant Plastic Surgeon Department of Plastic and Reconstructive SurgeryRoyal Free London NHS Foundation TrustLondonUK

Background:This systematic review aims to study the effectiveness of 5-fluorouracil(5FU)in the reduction of tendon adhesions postsurgical ***:A systematic review was performed involving four databases,Cochrane,PubMed,MEDLINE,and Embase,looking for evidence of at least Level I or Level II(according to NHMRC)in the use of 5FU in tendon repairs in human or animal ***:Across the four databases 546 articles were *** these 12 were identified as relevant,with a further two being excluded after in depth ***:Nine of the 10 studies showed that 5FU was effective at reducing tendon adhesions in their respective animal *** of the 10 studies showed no significant change compared to the control group.

关键词： 5FU animal models physiology plastics tendon

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Workhorse flaps for thumb reconstruction

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Plastic and Aesthetic Research 2022年第1期9卷 48-64页

作者： Ahmed M.Yassin Suvashis Dash dariush nikkhah Plastic Surgery Department Faculty of MedicineMansoura UniversityMansoura 35511Egypt Department of Plastic and Reconstructive Surgery All India Institute of Medical SciencesNew Delhi 110029India Division of Surgery&Interventional Science University College London UCLLondon NW32PFUK Department of Plastic Surgery Royal Free Hospital NHS Foundation TrustHampsteadLondon NW32QGUK

Posttraumatic thumb defects result in significant functional *** reconstructive procedures have been described for the management and improvement of *** with no treatment,all reconstructive methods are *** of the available procedures may be more applicable under certain conditions,can offer great benefits,and have its own downsides as *** a thorough assessment and meticulous technique,the results of thumb reconstruction can be *** present a review of the current reconstructive procedures for traumatic thumb amputation.

关键词： Thumb reconstruction soft tissue reconstruction of thumb thumb injury hand flaps

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