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Polariton lasing in Mie-resonant perovskite nanocavity

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Opto-Electronic Advances 2024年第4期7卷 27-42页

作者： Mikhail A.Masharin daria Khmelevskaia valeriy I.Kondratiev daria I.Markina Anton D.Utyushev Dmitriy M.Dolgintsev Alexey D.Dmitriev vanik A.Shahnazaryan Anatoly P.Pushkarev Furkan Isik Ivan v.Iorsh Ivan A.Shelykh Hilmi v.Demir Anton K.Samusev Sergey v.Makarov UNAM-Institute of Materials Science and Nanotechnology National Nanotechnology Research CenterDepartment of Electrical and Electronics EngineeringDepartment of PhysicsBilkent UniversityAnkara 06800Turkey ITMO University School of Physics and EngineeringSt.Petersburg 197101Russia Abrikosov Center for Theoretical Physics MIPTDolgoprudnyiMoscow Region 141701Russia LUMINOUS!Center of Excellence for Semiconductor Lighting and Displays School of Electrical and Electronic EngineeringSchool of Physical and Mathematical SciencesSchool of Materials Science and EngineeringNanyang Technological UniversitySingapore 639798Singapore Department of Physics Engineering Physics and AstronomyQueen’s UniversityKingstonOntario K7L 3N6Canada Science Institute University of IcelandDunhagi 3IS-107ReykjavikIceland Experimentelle Physik 2 Technische Universität DortmundDortmund 44227Germany Qingdao Innovation and Development Center Harbin Engineering UniversityQingdao 266000China

Deeply subwavelength lasers(or nanolasers)are highly demanded for compact on-chip bioimaging and sensing at the *** of the main obstacles for the development of single-particle nanolasers with all three dimensions shorter than the emitting wavelength in the visible range is the high lasing thresholds and the resulting *** we ex-ploit exciton-polariton condensation and mirror-image Mie modes in a cuboid CsPbBr3 nanoparticle to achieve coherent emission at the visible wavelength of around 0.53μm from its ultra-small(≈0.007μm3 or≈λ3/20)semiconductor *** polaritonic nature of the emission from the nanocavity localized in all three dimensions is proven by direct com-parison with corresponding one-dimensional and two-dimensional waveguiding systems with similar material *** a deeply subwavelength nanolaser is enabled not only by the high values for exciton binding energy(≈35 mev),re-fractive index(>2.5 at low temperature),and luminescence quantum yield of CsPbBr3,but also by the optimization of po-laritons condensation on the Mie resonances with quality factors improved by the metallic ***,the key parameters for optimal lasing conditions are intermode free spectral range and phonons spectrum in CsPbBr3,which govern polaritons condensation *** chemically synthesized colloidal CsPbBr3 nanolasers can be potentially de-posited on arbitrary surfaces,which makes them a versatile tool for integration with various on-chip systems.

关键词： nanolaser perovskite polariton Mie resonance exciton-polariton

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PD-1^(+)and TIM-3^(+)T cells widely express commonγ-chain cytokine receptors in multiple myeloma patients,and IL-2,IL-7,IL-15 stimulation up-regulates PD-1 and TIM-3 on T cells

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Oncology Research 2024年第10期32卷 1575-1587页

作者： EGOR v.BATOROv ALISA D.INESHINA TATIANA A.ARISTOvA vERA v.DENISOvA SvETLANA A.SIZIKOvA daria S.BATOROvA GALINA Y.USHAKOvA EKATERINA Y.SHEvELA ELENA R.CHERNYKH Laboratory of Cellular Immunotherapy Research Institute of Fundamental and Clinical ImmunologyNovosibirsk630099Russia v.Zelman Institute of Medicine and Psychology Novosibirsk National Research State UniversityNovosibirsk630090Russia Department of Hematology and Bone Marrow Transplantation Research Institute of Fundamental and Clinical ImmunologyNovosibirsk630099Russia

Background:Immune checkpoint ligand-receptor interactions appear to be associated with multiple myeloma(MM)***,previous studies showed the possibility of PD-1 and TIM-3 expression on T cells upon stimulation with commonγ-chain family cytokines in vitro and during homeostatic *** aim of the present work was to study the impact of homeostatic proliferation on the expansion of certain T cell subsets upregulating PD-1 and TIM-3 checkpoint ***:The expression of CD25,CD122,CD127 commonγ-chain cytokine receptors,phosphorylated signal transducer and activator of transcription-5(pSTAT5)and eomesodermin(EOMES)was comparatively assessed with flow cytometry in PD-1-and TIM-3-negative and positive T cells before the conditioning and during the first post-transplant month in peripheral blood samples of MM ***:Substantial proportions of PD-1-and TIM-3-positive T lymphocytes expressed commonγ-chain cytokine receptors and *** of cytokine receptor expressing cells were significantly higher within TIM-3+T cells compared to PD-1+TIM-3−*** proportions of both PD-1-/TIM-3-negative and positive CD8+T cells express EOMES,while only moderate frequencies of CD4+PD-1+/TIM-3+T cells up-regulate this transcription ***,the surface presence of CD25 and intranuclear expression of EOMES in CD4+T cells were mutually exclusive regardless of PD-1 and TIM-3 *** stimulation with commonγ-chain cytokines up-regulates PD-1 and TIM-3 during the proliferation of initially PD-1/TIM-3-negative T cells but fails to expand initially PD-1+and TIM-3+T cell subsets in ***:Both PD-1 and TIM-3 expressing T cells appear to be able to respond to homeostatic cytokine *** in commonγ-chain cytokine receptor expression between PD-1+and TIM-3+T cells may reflect functional dissimilarity of these cell *** blockade appears to alleviate lymphopenia-induced prolif

关键词： Autologous hematopoietic stem cell transplantation(AHSCT) CD25 CD122 Eomesodermin(EOMES) Homeostatic proliferation

A rened analytical model for reconstruction problems in diuse reectance spectroscopy

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Journal of Innovative Optical Health Sciences 2024年第5期17卷 33-51页

作者： Ekaterina Sergeeva daria Kurakina Ilya Turchin and Mikhail Kirillin A.v.gaponov-grekhov institute of applied physics of the russian academy of sciences ulyanov st.46 603950nizhny novgorodrussia

A rened analytical model of spatially resolved diffuse reectance with small source-detector separations(SDSs)for the in vivo skin studies is *** to the conventional model developed by Farrell et al.,it accounts for the limited acceptance angle of the *** rened model is validated in the wide range of optical parameters by Monte Carlo simulations of skin diffuse reectance at SDSs of units of *** of uniform dermis and two-layered epidermis-dermis structures are *** accuracy of the rened model compared to the conventional one is demonstrated in the separate,constraint-free reconstruction of absorption and reduced scattering spectra of uniform dermis from the Monte Carlo simulated *** the case of epidermis-dermis geometry,the recovered values of reduced scattering in dermis are overestimated and the recovered values of absorption are underestimated for both analytical ***,in the presence of a thin mismatched topical layer,only the effective attenuation coe±cient of the bottom layer can be accurately recovered using a diffusion theorybased analytical model while separate reconstruction of absorption and reduced scattering fails due to the inapplicability of the method of ***-ndings require implementation of more sophisticated models of light transfer in inhomogeneous media in the recovery algorithms.

关键词： Diffuse reffectance spectroscopy in vivo skin studies optical properties reconstruction diffuse approximation Monte Carlo simulations method of images

Increasingβ-hexosaminidase A activity using genetically modified mesenchymal stem cells

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Neural Regeneration Research 2024年第1期19卷 212-219页

作者： Alisa A.Shaimardanova daria S.Chulpanova valeriya v.Solovуeva Shaza S.Issa Aysilu I.Mullagulova Angelina A.Titova Yana O.Mukhamedshina Anna v.Timofeeva Alexander M.Aimaletdinov Islam R.Nigmetzyanov Albert A.Rizvanov Institute of Fundamental Medicine and Biology Kazan Federal UniversityKazanRussia Department of Histology Cytology and EmbryologyKazan State Medical UniversityKazanRussia

GM2 gangliosidoses are a group of autosomal-recessive lysosomal storage disorde *** diseases result from a deficiency of lysosomal enzymeβ-hexosaminidase A(HexA),which is responsible for GM2 ganglioside *** deficiency causes the accumulation of GM2-gangliosides mainly in the nervous system cells,leading to severe progressive neurodegeneration and *** date,there is no treatment for these ***-mediated gene therapy is considered a promising treatment for GM2 *** study aimed to evaluate the ability of genetically modified mesenchymal stem cells(MSCs-HEXA-HEXB)to restore HexA deficiency in Tay-Sachs disease patient cells,as well as to analyze the functionality and biodistribution of MSCs in *** effectiveness of HexA deficiency cross-correction was shown in mutant MSCs upon intera ction with *** results also showed that the MSCs-HEXA-HEXB express the functionally active HexA enzyme,detectable in vivo,and intravenous injection of the cells does not cause an immune response in *** data suggest that genetically modified mesenchymal stem cells have the potentials to treat GM2 gangliosidoses.

关键词： adeno-associated viral vectors cell therapy cell-mediated gene therapy gene therapy GM2 gangliosidosis Sandhoff disease Tay-Sachs disease β-hexosaminidase

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In-situ study of the microstructure evolution during tension of a Mg-Y-Zn-Al alloy processed by rapidly solidified ribbon consolidation technique

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Journal of Magnesium and Alloys 2024年第5期12卷 2024-2040页

作者： Jeno Gubicza Kristián Máthis Péter Nagy Péter Jenei Zoltán Hegedus Andrea Farkas Jozef vesely Shin-ichi Inoue daria Drozdenko Yoshihito Kawamura Department of Materials Physics Faculty of ScienceEotvos Loránd UniversityPázmány P.sétány 1/ABudapest H-1117Hungary Department of Physics of Materials Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116 Praha 2Czech Republic Deutsches Elektronen-Synchrotron DESY Notkestr.85Hamburg 22603Germany Magnesium Research Center Kumamoto University2-39-1 KurokamiChuo-kuKumamoto 860-8555Japan

Mg-Y-Zn-Al alloys processed by rapidly solidified ribbon consolidation(RSRC)technique exhibit an exceptional mechanical performance indicating promising application *** material has a bimodal microstructure consisting of fine recrystallized and coarse non-recrystallized grains with solute-rich stacking faults forming cluster arranged layers(CALs)and nanoplates(CANaPs),or complete long period stacking ordered(LPSO)*** order to reveal the deformation mechanisms,in-situ synchrotron X-ray diffraction line profile analysis was employed for a detailed study of the dislocation arrangement created during tension in Mg-0.9%Zn-2.05%Y-0.15%Al(at%)*** uncovering the effect of the initial microstructure on the mechanical performance,additional samples were obtained by annealing of the as-consolidated specimen at 300 and 400℃ for 2 *** heat treatment at 300℃ had no significant effect on the initial microstructure,its evolution during tension and,thus,the overall deformation behavior under tensile *** the other hand,annealing at 400℃ resulted in a significant increase of the recrystallized grains fraction and a decrease of the dislocation density,leading to only minor degradation of the mechanical *** maximum dislocation density at the failure of the samples corresponding to the plastic strain of 10-25% was estimated to be about 16-20×10^(14)m^(-2).The diffraction profile analysis indicated that most dislocations formed during tension were of non-basal and pyramidal types,what was also in agreement with the Schmid factor values revealed independently from orientation *** was also shown that the dislocation-induced Taylor hardening was much lower below the plastic strain of 3% than above this value,which was explained by a model of the interaction between prismatic dislocations and CANaPs/LPSO plates.

关键词： Mg-Zn-Y-Al alloy Long period stacking ordered(LPSO)phase Cluster arranged nanoplates(CANaPs) Annealing Tension Dislocation density Hardening

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Multifunctional 2D materials for antiviral protection and detection

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National Science Review 2022年第5期9卷 8-9页

作者： daria v.Andreeva Kostya S.Novoselov Department of Materials Science and Engineering National University of Singapore Chongqing 2D Materials Institute National Graphene Institute University of Manchester

Two-dimensional (2D) materials [1]with their high surface to volume ratio,flexibility,tunable electronic properties,and most importantly—the large variety of the properties covered by the members of the 2D family—have already found their way to many applications in very different areas of technology[2].One of the most promising areas of applications for 2D crystals remains healthcare [3],where such materials have been considered for drug delivery,

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Factors Contributing to Contamination of Street Foods in Bamako, Mali

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Food and Nutrition Sciences 2024年第3期15卷 199-210页

作者： Demba Dembele Mamadou Wele Bawa Boya Haziz sina Basile Boni Saka Konmy Adolphe Adjanohoun Lamine Baba-Moussa Institute of Applied Sciences University of Sciences Techniques and Technologies of Bamako Bamako Mali Laboratory of Biology and Molecular Typing in Microbiology Faculty of Science and Technology University of Abomey-Calavi Cotonou Benin National Agronomic Research Institute of Benin Cotonou Benin

The World Health Organization states that foodborne diseases are a worldwide public health issue. Although street foods can provide nutritious and affordable ready-to-eat meals for city dwellers, their health risks can outweigh the benefits. A cross-sectional study was conducted in the Bamako district, focusing on street food vendors near schools, universities, extensive markets, administrative centers, and major roads. We aimed to sample fifty (50) sellers per municipality, making 300 sellers for the Bamako district. We developed a survey sheet to collect data, and six teams rotated between the municipalities each month. Before starting the collection, the teams were provided administrative papers approved by the municipal authority. The survey revealed three types of sales sites: fixed (65%), semi-fixed (30%), and mobile (4.40%). The proportion of sellers was 26.8%, 23.2%, 19.7%, and 4.2% in municipalities III, Iv, and I. In municipalities I, II, III, Iv, and vI, respectively, 92%, 95.70%, 93%, 87.2%, and 100% of the sellers were female. The age distribution of sellers was 65.63%, 46.81%, 40.82%, 38.30%, 36.17%, 36%, and 32% in the 25-34 and 35 - 44 age groups. Illiteracy rates were 59.20%, 61.70%, 55.30%, 75%, and 56% in municipalities I, II, III, Iv, and vI, respectively. The study identified two categories of sellers: 48.3% in type 1 and 51.7% in type 2. The first category comprised 154 sellers, and the second 165 sellers. The survey found that 66.00%, 56.00%, 48.90%, 44.90%, 38.30%, and 34.40% of municipal v, vI, III, I, II, and Iv sales sites were open-air. In municipality I, 63.30% of the sites were under hangars, while in municipalities II and Iv, the corresponding percentages were 51.10% and 59.40%, respectively. Moreover, 46.00%, 31.90%, 31.30%, 30.60%, and 27.70% of the sites in municipalities vI, II, Iv, I, and III were located next to gutters. In conclusion, this study identified several factors that could compromise the quality of street foods sold in

关键词： Factors Source Contamination Street Food Bamako

Integral Cayley Graphs over Finite Groups

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Algebra Colloquium 2020年第1期27卷 131-136页

作者： Elena vKonstantinova daria Lytkinat Sobolev Institute of Mathematics Ak.Koptyug av.4Novosibirsk 630090Russia Novosibirsk State University Pirogovastr.2Novosibirsk 630090Russia Siberian State University of Telecommunications and Information Sciences Kirova str.86 Novosibirsk 630108Russia Novosibirsk State University Pirogova str.2Novosibirsk 630090Russia

We prove that the spectrum of a Cayley graph over a finite group with a normal generating set S containing with every its element s all generators of the cyclic group(s)is *** particular,a Cayley graph of a 2-group generated by a normal set of involutions is *** prove that a Cayley graph over the symmetric group of degree n no less than 2 generated by all transpositions is *** find the spectrum of a Cayley graph over the alternating group of degree n no less than 4 with a generating set of 3-cycles of the form(k i j)with fixed k,a s{-n+1,1-n+1,2^2-n+1,...,(n-1)2-n+1}.

关键词： Cayley graph symmetric group alternating group group algebra Star graph

Grinding exfoliation for scalable production of 2D materials

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National Science Review 2020年第3期7卷 559-560页

作者： Kostya S.Novoselov Qi Ge daria v.ANDreeva Department of Materials Science and Engineering National University of Singapore National Graphene Institute University of Manchester

Over the past few years the utilisation of graphene in various areas of industry has strongly intensified [1]. Applications in thermal management, composite materials and energy consume an increasing amount of this tw... 详细信息

关键词： Grinding exfoliation for scalable production of 2D materials Graphene