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Recent advances in laser self-injection locking to high-Q microresonators

Frontiers of physics 2023年第2期18卷 89-130页

作者： Nikita m.Kondratiev Valery E.Lobanov Artem E.Shitikov Ramzil R.Galiev Dmitry A.Chermoshentsev Nikita Yu.Dmitriev Andrey N.Danilin Evgeny A.Lonshakov Kirill N.min’kov daria m.sokol Steevy J.Cordette Yi-Han Luo Wei Liang Junqiu Liu Igor A.Bilenko Directed Energy Research Centre Technology Innovation InstituteAbu DhabiUnited Arab Emirates Russian Quantum Center MoscowRussia Skolkovo Institute of Science and Technology SkolkovoRussia moscow Institute of Physics and Technology DolgoprudnyMoscow RegionRussia Faculty of Physics Lomonosov Moscow State UniversityMoscowRussia Shenzhen Institute for Quantum Science and Engineering Southern University of Science and TechnologyShenzhen 518055China International Quantum Academy Shenzhen 518048China Key Laboratory of Nanodevices and Applications Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China Hefei National Laboratory University of Science and Technology of ChinaHefei 230026China

The stabilization and manipulation of laser frequency by means of an external cavity are nearly ubiquitously used in fundamental research and laser applications. While most of the laser light transmits through the cavity, in the presence of some back-scattered light from the cavity to the laser, the self-injection locking effect can take place, which locks the laser emission frequency to the cavity mode of similar frequency. The self-injection locking leads to dramatic reduction of laser linewidth and noise. Using this approach, a common semiconductor laser locked to an ultrahigh-Q microresonator can obtain sub-Hertz linewidth, on par with state-of-the-art fiber lasers. Therefore it paves the way to manufacture high-performance semiconductor lasers with reduced footprint and cost. moreover, with high laser power, the optical nonlinearity of the microresonator drastically changes the laser dynamics, offering routes for simultaneous pulse and frequency comb generation in the same microresonator. Particularly, integrated photonics technology, enabling components fabricated via semiconductor CmOS process, has brought increasing and extending interest to laser manufacturing using this method. In this article, we present a comprehensive tutorial on analytical and numerical methods of laser self-injection locking, as well a review of most recent theoretical and experimental achievements.

关键词： self-injection locking laser stabilization microresonator nonlinearity single-frequency lasing multi-frequency lasing

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High current limits in chemical vapor deposited graphene spintronic devices

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Nano Research 2023年第4期16卷 4233-4239页

作者： daria Belotcerkovtceva J.Panda m.Ramu Tapati Sarkar Ulrich Noumbe m.Venkata Kamalakar Department of Physics and Astronomy Uppsala UniversityBox 516Uppsala SE-75120Sweden Department of materials Science and Engineering Uppsala UniversityBox 35Uppsala SE-75103Sweden

Understanding the stability and current-carrying capacity of graphene spintronic devices is key to their applications in graphene channel-based spin current sensors,spin-torque oscillators,and potential spin-integrated ***,despite the demonstrated high current densities in exfoliated graphene,the current-carrying capacity of large-scale chemical vapor deposited(CVD)graphene is not ***,the grainy nature of chemical vapor deposited graphene and the presence of a tunnel barrier in CVD graphene spin devices pose questions about the stability of high current electrical spin *** this work,we observe that despite structural imperfections,CVD graphene sustains remarkably highest currents of 5.2×10^(8)A/cm^(2),up to two orders higher than previously reported values in multilayer CVD graphene,with the capacity primarily dependent upon the sheet resistance of ***,we notice a reversible regime,up to which CVD graphene can be operated without degradation with operating currents as high as 108 A/cm^(2),significantly high and durable over long time of operation with spin valve signals observed up to such high current *** the same time,the tunnel barrier resistance can be modified by the application of high *** results demonstrate the robustness of large-scale CVD graphene and bring fresh insights for engineering and harnessing pure spin currents for innovative device applications.

关键词： chemical vapor deposited(CVD)graphene high current density graphene spintronics spin integrated circuits graphene spin valve

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mixed phase sodium manganese oxide as cathode for enhanced aqueous zinc-ion storage

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Chinese Journal of Chemical Engineering 2020年第8期28卷 2214-2220页

作者： Xinyu Wang Xinghua Qin Qiongqiong Lu mingming Han Ahmad Omar daria mikhailova Institute of materials and Technology Dalian Maritime UniversityDalian 116026China Leibniz Institute for Solid State and materials Research(IFW)Dresden e.V. Helmholtzstraße 2001069 DresdenGermany School of materials Science and Engineering Central South UniversityChangsha 410083China

Aqueous zinc-ion batteries have been regarded as a promising alternative to large-scale energy storage, due to associated low-cost, improved safety and environmental friendliness. However, a high-performance cathode material for both rate capability and specific capacity is still a challenge. One kind of the more promising candidates are sodium manganese oxide(NmO) materials, although they suffer from individual issues and need to be further improved. Herein, we present a novel mixed phase NmO material composed of nearly equal amounts of Na(0.55)mn2O4 and Na(0.7)mnO(2.05). The structured configuration with particle size of 200–500 nm is found to be beneficial towards improving the ion diffusion rate during the charge/discharge process. Compared with Na(0.7)mnO(2.05) and Na(0.55)mn2O4, the mixed phase NmO demonstrates an enhanced rate capability and excellent long-term cycling stability with a capacity retention of 83% after 800 cycles. more importantly, the system also delivers an impressive energy density and power density, as 378 W·h·kg^-1 at 68.7 W·kg^-1, or 172 W·h·kg^-1 at 1705 W·kg^-1. The superior electrochemical performance is ascribed to the fast Zn^2+ diffusion rate because of a large ratio of capacitive contribution(63.9% at 0.9 m V·s^-1). Thus, the mixed phase route provides a novel strategy to enhance electrochemical performance, enabling mixed phase NmO as very promising material towards large-scale energy-storage applications.

关键词： Aqueous zinc-ion battery Sodium manganese oxide mixed phase High energy density

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Functionality of a bicistronic construction containing HEXA and HEXB genes encoding β-hexosaminidase A for cell-mediated therapy of Gm2 gangliosidoses

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Neural Regeneration Research 2022年第1期17卷 122-129页

作者： Alisa A.Shaimardanova daria S.Chulpanova Valeriya V.Solovyeva Aleksandr m.Aimaletdinov Albert A.Rizvanov Institute of Fundamental medicine and Biology Kazan Federal UniversityKazanRussia

Tay-Sachs disease and Sandhoff disease are severe hereditary neurodegenerative disorders caused by a deficiency ofβ-hexosaminidase A(HexA)enzyme,which results in the accumulation of Gm2 gangliosides in the nervous system *** this work,we analyzed the efficacy and safety of cell-mediated gene therapy for Sandhoff disease and Sandhoff disease using a bicistronic lentiviral vector encoding cDNA of HexAα-andβ-subunit genes separated by the nucleotide sequence of a P2A peptide(HEXA-HEXB).The functionality of the bicistronic construct containing the HEXA-HEXB genetic cassette was analyzed in a culture of HEK293T cells and human umbilical cord blood mononuclear cells(hUCBmCs).Our results showed that the enzymatic activity of HexA in the conditioned medium harvested from genetically modified HEK293T-HEXA-HEXB and hUCBmCs-HEXA-HEXB was increased by 23 and 8 times,respectively,compared with the conditioned medium of native *** blot analysis showed that hUCBmCs-HEXA-HEXB secreted both completely separated HEXA and HEXB proteins,and an uncleaved protein containing HEXA+HEXB linked by the P2A *** injection of genetically modified hUCBmCs-HEXA-HEXB to laboratory Wistar rats was carried out,and the HexA enzymatic activity in the blood plasma of experimental animals,as well as the number of live cells of immune system organs(spleen,thymus,bone marrow,lymph nodes)were determined.A significant increase in the enzymatic activity of HexA in the blood plasma of laboratory rats on days 6 and 9(by 2.5 and 3 times,respectively)after the administration of hUCBmCsHEXA-HEXB was *** the same time,the number of live cells in the studied organs remained ***,the functionality of the bicistronic genetic construct encoding cDNA of the HEXA and HEXB genes separated by the nucleotide sequence of the P2A peptide was shown in vitro and in *** hypothesize that due to the natural ability of hUCBmCs to overcome biological barriers,such a strategy can rest

关键词： bicistronic vector cell-mediated gene therapy Gm2 gangliosidosis P2A peptide Sandhoff disease Tay-Sachs disease umbilical cord blood mononuclear cells β-hexosaminidase

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Evidence for a con served microbiota across the different developmental stages of Plodia interpunctella

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Insect Science 2019年第3期26卷 466-478页

作者： Valeria mereghetti Bessem Chouaia Lidia Limonta daria Patrizia Locatelli matteo montagna Dipartimento di Scienze Agrarie e Ambientali Universita degli Studi di Milano Milan Italy Dipartimento di Scienze per gli Alimenti la Nutrizione I'Ambiente Universita degli Studi di Milano Milan Italy

Diversity and composition of lepidopteran microbiotas are poorly investigated, especially across the different developmental stages. To improve this knowledge, we characterize the microbiota among different developmental stages of the Indian meal moth, Plodia interpunctella, which is considered one of the major pest of commodities world-wide. Using culture-independent approach based on Illumina 16S rRNA gene sequencing we characterized the microbiota of four developmental stages: eggs, first-, and last-instar larvae, and adult. A total of 1022 bacterial OTUs were obtained, showing a quite diversified microbiota associated to all the analyzed stages. The microbiotas associated with P. interpunctella resulted almost constant throughout the developmental stages, with approximately 77% of bacterial OTUs belonging to the phylum of Proteobacteria. The dominant bacterial genus is represented by Burkholderia (?64%), followed by Propionibacterium, Delftia, Pseudomonas, and Stenotrophomonas. A core bacterial community, composed of 139 OTUs, was detected in all the developmental stages, among which 112 OTUs were assigned to the genus Burkholderia. A phylogenetic reconstruction, based on the 16S rRNA, revealed that our Burkholderia OTUs clustered with Burkholderia cepacia complex, in the same group of those isolated from the hemipterans Gossyparia spuria and Acanthococcus aceris. The functional profiling, predicted on the base of the bacterial 16S rRNA, indicates differences in the metabolic pathways related to metabolism of amino acids between preimaginal and adult stages. We can hypothesize that bacteria may support the insect host during preimaginal stages.

关键词： Burkholderia Illumina sequencing Indian meal moth insect symbiosis Proteobacteria

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Hot deformation of mg-Y-Zn alloy with a low content of the LPSO phase studied by in-situ synchrotron radiation diffraction

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Journal of magnesium and Alloys 2020年第1期8卷 199-209页

作者： Klaudia Horváth Fekete daria Drozdenko Jan Capek Kristián máthis Domonkos Tolnai Andreas Stark Gerardo Garcés Patrik Dobron Department of Physics of materials Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116 PragueCzech Republic Nuclear Physics Institute of the CAS 25068ˇRežCzech Republic magnesium Research Center Kumamoto University2-39-1 Kurokami Chuo-ku860-8555 KumamotoJapan Laboratory for Neutron Scattering and Imaging Paul Scherrer InstituteVilligen PSI5232Switzerland Institute of materials Science Helmholtz-Zentrum GeesthachtMax-Planck Str.1GeesthachtD21502Germany Department of Physical metallurgy CENIM-CSICAvenida Gregorio del Amo 8E-28040 MadridSpain

The compressive deformation behavior of the extruded WZ42(mg98.5Y1Zn0.5 in at.%)magnesium alloy containing a low amount of long-period stacking ordered(LPSO)phase was studied by in-situ synchrotron radiation diffraction *** were conducted at temperatures between room temperature and 350℃.Detailed microstructure investigation was provided by scanning electron microscopy,particularly the backscattered electron imaging and electron backscatter diffraction *** results show that twinning lost its dominance and kinking of the LPSO phase became more pronounced with increasing deformation *** cracks of the LPSO phase and no debonding r at the interface between the LPSO phase and the mg matrix were observed at temperatures above 200℃.At 350℃,the LPSO phase lost its strengthening effect and the deformation of the alloy was mainly realized by the dynamic recrystallization of the mg matrix.

关键词： magnesium alloy LPSO phase Kinking High temperature Synchrotron radiation diffraction

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High Impact Polylactide Based on Organosilicon Nucleation Agent

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Chinese Journal of Polymer Science 2024年第6期42卷 787-797页

作者： daria Pakuła Bogna Sztorch Eliza Romańczuk-Ruszuk Bogdan marciniec Robert E.Przekop Faculty of Chemistry Adam Mickiewicz University in PoznańUniwersytetu Poznańskiego 861-614PoznańPoland Centre for Advanced Technologies Adam Mickiewicz University in PoznańUniwersytetu Poznańskiego 1061-614PoznańPoland Institute of Biomedical Engineering Faculty of Mechanical EngineeringBialystok University of TechnologyWiejska 45C15-351BialystokPoland

Various sectors of the industry are searching for new materials with specific requirements,providing improved *** study presents novel composite materials based on polylactide that have been modified with the organosilicon compound,(3-thiopropyl)polysilsesquioxane(SSQ-SH).The SSQ-SH compound is a mixture of cage structures and not fully condensed random *** composite materials were obtained through injection *** study includes a comprehensive characterization of the new materials that analyze their functional properties,such as rheology(mFR),mechanical strength(tensile strength,Charpy impact strength),and thermal *** microscopic photos were also taken to analyze the microstructure of the *** addition of a 5%by-weight organosilicon compound to polylactide resulted in a significant increase in mFR by 73.8%compared to the neat *** greatest improvement in impact strength was achieved for the 5%SSQ-SH/PLA composite,increasing it by 32.0 kJ/m^(2)compared to PLA,which represents an increase of up to 187%.The conducted research confirms the possibility of modifying the properties of the polymer by employing organosilicon compounds.

关键词： Octa(3-thiopropyl)silsesquioxane 8SH-POSS Polylactide(PLA) Injection moulding Composites

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Preclinical models in ophthalmic oncology-a narrative review

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Annals of Eye Science 2022年第2期7卷 59-73页

作者： daria Lehrmann Nasrin Refaian michael Simon Alexander C.Rokohl Ludwig m.Heindl Department of Ophthalmology Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Integrated Oncology(CIO) Aachen-Bonn-Cologne-DüsseldorfCologneGermany

Objective:This review serves as a comprehensive description and summary of currently available preclinical models of three tumors in ophthalmic oncology:conjunctival melanoma(Cm),uveal melanoma(Um),and ***:malignant melanomas are the most common tumors of the eye in adults,most often localized in the uvea and *** the primary tumor can be successfully eliminated in many cases,nearly one in two Ums-and one in three Cms-are fatal to the patient due to *** therapies for metastatic uveal and Cms are unfortunately still not available,so there is an urgent need for new therapeutic strategies to improve prognosis quoad vitam and prolong the survival of melanoma *** widely known tumor of the eye is retinoblastoma,which is the most common pediatric ocular malignancy,occurring in approximately 1 in 15,000-18,000 live ***,it is considered well treatable,with a survival rate of approximately 90%at 3 years,although fatal if *** a long time,enucleation was also considered the treatment of choice,with bilateral cases having one eye irradiated and the eye with the more advanced tumor *** the 1990s,however,systemic chemotherapy has been predominantly used to preserve the quality of life and vision of young patients,although the cellular activity of the retinoblastoma often remains after treatment with chemotherapeutic *** of the disease is immensely depending on the stage and time of diagnosis and is varying between countries due to different developmental status of health care ***:We review recent advances in the available literature on established preclinical models in Cm,Um,and *** addition,we discuss the advantages and limitations of these models and provide an overview of current alternatives to animal testing in preclinical ***:In the case of all three diseases,further research is needed for improved therapeutic ***

关键词： Conjunctival melanoma(Cm) uveal melanoma(Um) retinoblastoma ocular tumor preclinical models

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The Clinical Use of mediator Release Test in Food Sensitivities

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Journal of Food Science and Engineering 2018年第1期8卷 61-63页

作者： daria m. Adamczak Private Clinic Derma Solutions Szczepankowo 94A Poznan 61-306 Poland Poznan University of medical Sciences Coll. Maius Fredry 10 Poznan 61-701 Poland

Food sensitivities are non-IgE-mediated, non-coeliac, dose-dependent and delayed systemic responses to food. They consist of a highly complex class of adverse food reactions; however, their last phase is the release of mediators from leukocytes. The mediator Release Test （mRT） is a functional measure of sensitivity-based inflammatory responses. It is an end-point test, which can account for the widest range of triggering mechanisms involved in sensitivity reactions, including both innate and adaptive pathways. mRT not only tests reactions to foods, food-chemicals, and other substances, but also reliably quantifies the degree of the inflammatory response. The test opens the new therapeutic options for food sensitivities.

关键词： mRT adverse food reactions food sensitivity.

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Graphene and other two-dimensional materials

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Frontiers of physics 2019年第1期14卷 1-4页

作者： Kostya S. Novoselov daria V. Andreeva Wencai Ren Guangcun Shan School of Physics and Astronomy University of Manchester Manchester M13 9PL United Kingdom National Graphene Institute University of Manchester Manchester M13 9PL United Kingdom Centre for Advanced 2D materials and Graphene Research Centre National University of Singapore 6 Science Drive 2 117546 Singapore Shenyang National Laboratory for materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China School of Instrumentation Science and Opto-electronics Engineering Beihang University Beijing 100191 China

Over the last few years,research on graphene [1-3]has progressed significantly,and as a result,a number of reallife applications of graphene have been realized [4,5].This carbon allotrope (for a review on other forms of carbon, see [6])resulted in a number of novel physical phenomena already discovered (ranging from new types of quantum Hall effect to universal optical conductivity)and dramatically expanded the range of possible applications for such materials (from transparent conductive coating to ultrafast photodetectors).

关键词： Graphene two-dimensional materials universal optical conductivity

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