检索结果-南通市图书馆

Readily prepared and processed multifunctional MXene nanocomposite hydrogels for smart electronics

在线全文

学校读者我要写书评

暂无评论

SmartMat 2024年第2期5卷 103-114页

作者： Jiahui huang Xianwu huang Peiyi Wu State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Chemistry and Chemical EngineeringCenter for Advanced Low-Dimension MaterialsDonghua UniversityShanghaiChina State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Science and Laboratory of Advanced MaterialsFudan UniversityShanghaiChina

Booming sophisticated robotics and prosthetics put forward high requirements on soft conductive materials that can bridge electronics and biology,those soft conductive materials should imitate the mechanical properties of biological tissues and build information transmission *** now,it remains a great challenge to handle the trade-off among ease of preparation,high conductivity,processability,mechanical adaptability,and external stimuli ***,a kind of readily prepared and processed multifunctional MXene nanocomposite hydrogel is reported,which is prepared via the fast gelation of cationic monomer initiated by delaminated MXene *** gelation time can be adjusted(several seconds to minutes)based on the MXene *** adjusting the MXene ratio,the resulting nanocomposites are ultrastretchable(>5000%),three-dimensional(3D)printable,and show outstanding mechanical and electrical *** expected,the integration of multifunctional systems onto various substrates(e.g.,gloves and masks)is further demonstrated via 3D printing and could achieve diverse sensory capabilities toward strain,pressure,and temperature,showing great prospects as smart flexible electronics.

关键词： 3D printable electronics MXene polymeric hydrogels stretchable and conductive

Challenges and Opportunities of Sub-6 GHz Integrated Sensing and Communications for 5G-Advanced and Beyond

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2024年第2期33卷 323-325页

作者： Yuhong huang China Mobile Research Institute China Mobile Communications Group Co. Ltd

The integrated sensing and communications(ISAC) technology has been perceived as a key feature of5G-Advanced and beyond mobile communication networks. Compared with sensing in millimeter-wave bands, sensing at sub-6 GHz band is an exceptional incentive to promote the industrialization process of ISAC due to its incomparable advantages in industrial development, especially for intelligent transportation and smart drone networks. This paper elaborates on the top challenges of sub-6 GHz ISAC technologies, as well as the potential solutions to improve the sensing capability.

关键词： Electric potential Millimeter wave technology Transportation Mobile communication Sensors Millimeter wave communication Drones

Enhanced boron neutron capture therapy(BnCT)through controlled drug release via boron-loaded nanofiber mats

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

nano Research 2024年第8期17卷 7479-7492页

作者： Wenyong huang Yongjin Yang Yong Pan Shiwei Jing Yanxin Qi Yubin huang Faculty of Chemistry Northeast Normal UniversityChangchun 130024China Key Laboratory of Sustainable Advanced Functional Materials of Jilin Province Changchun 130024China School of Physics Northeast Normal UniversityChangchun 130024China

Boron neutron capture therapy(BnCT)is a novel binary therapy combining boron targeted drugs and neutron irradiation,which can selectively and effectively kill cancer cells at the cellular *** release of boron drug and its accumulation in tumor sites are the crux of ***,we developed a^(10)B-boric acid(^(10)BA)-loaded nanofiber applying for BnCT by in situ *** nanofibers were obtained by electrospinning technique using polyethylene glycol/polylactide(PEO/PLA)block *** changing the ratio of hydrophilicity to hydrophobicity of the nanofibers,the controlled release and the effective accumulation of boron 10 isotope(^(10)B)were achieved in ***^(10)B content in tumor could reach to 2540μg/g,significantly exceeding the required level of 20–50μg/g for BnCT *** pertinent DnA damage experiments,direct evidence and quantified data of BnCT-induced DnA damage in tumor cells were obtained for the first *** sequencing was employed to predict the molecular mechanisms and potential signaling pathways of BnCT,providing theoretical basis for future combined *** antitumor efficiency of BnCT was demonstrated by establishing mice model of subcutaneous tumor and tumor *** research presents a novel boron-loaded nanofiber mats for BnCT,which enables controlled drug release and holds significant potential in the treatment of unresectable or postoperative residual tumors.

关键词： boron neutron capture therapy nanofibers controlled release in situ administration

Reduced-Order Observer-Based LQR Controller Design for Rotary Inverted Pendulum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第7期140卷 305-323页

作者： Guogang Gao LeiXu Tianpeng huang Xuliang Zhao Lihua huang College of Engineering China University of Petroleum-Beijing at KaramayKaramay834000China School of Electrical Engineering and Information Southwest Petroleum UniversityChengdu610500China

The Rotary Inverted Pendulum(RIP)is a widely used underactuated mechanical system in various applications such as bipedal robots and skyscraper stabilization where attitude control presents a significant *** the implementation of various control strategies to maintain equilibrium,optimally tuning control gains to effectively mitigate uncertain nonlinearities in system dynamics remains *** methods frequently rely on extensive experimental data or the designer’s expertise,presenting a notable *** paper proposes a novel tracking control approach for RIP,utilizing a Linear Quadratic Regulator(LQR)in combination with a reduced-order ***,the RIP system is mathematically modeled using the newton-Euler-Lagrange ***,a composite controller is devised that integrates an LQR for generating nominal control signals and a reduced-order observer for reconstructing unmeasured *** approach enhances the controller’s robustness by eliminating differential terms from the observer,thereby attenuating unknown *** numerical simulations and experimental evaluations demonstrate the system’s capability to maintain balance below50Hz and achieve precise tracking below1.4 rad,validating the effectiveness of the proposed control scheme.

关键词： Rotary inverted pendulum(RIP) linear quadratic regulator(LQR) reduced-order observer states estimate

Hybrid HMX multi-level assembled under the constraint of 2D materials with efficiently reduced sensitivity and optimized thermal stability

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第9期39卷 123-132页

作者： Xiaomin Song Longjin huang Rufang Peng Qi huang Jinjiang Xu Jie Sun Institute of Chemical Materials China Academy of Engineering PhysicsMianyang621900China State Key Laboratory of Environment-friendly Energy Materials School of Materials Science and EngineeringSouthwest University of Science and TechnologyMianyang621010China

The interfacial interaction between HMX molecules and coating materials is the key to the safety performance of explosives and has received extensive ***,screening suitable coating agents to enhance the interfacial effect to obtain high-energy and low-sensitivity explosives has long been a major *** this work,HMX-PEI/rGO/g-C_(3)n_(4)(HPrGC)composites were innovatively prepared by a multi-level coating strategy of two-dimensional graphite rGO and g-C_(3)n_(4).The g-C_(3)n_(4) used for desensitization has a richπ-conjugated system and shows outstanding ability in reducing friction *** hierarchical structure of HPrGC formed by electrostatic self-assembly andπ-πstacking can effectively dissipate energy accumulation under heat and mechanical stimulation through structural evolution,thus exhibiting a prominent synergistic desensitization effect on *** results show that rGO/gC_(3)n_(4) coating has no effect on the crystal structure and chemical structure of *** importantly,the perfect combination of g-C_(3)n_(4) and rGO endows HPrGC with enhanced thermal stability and ideal mechanical sensitivity(IS:21 J,FS:216 n).Obviously,the new fabrication of HPrGC enriches the variety of desensitizer materials and helps to deepen the understanding of the interaction between explosives and coatings.

关键词： HMX-PEI/rGO/g-C_(3)n_(4) Electrostatic self-assembly π-πstacking Synergistic desensitization

Mechanical parameter evolutions and deterioration constitutive model for ductile-brittle failure of surrounding rock in high-stress underground engineering

在线全文

学校读者我要写书评

暂无评论

Underground Space 2024年第2期15卷 131-152页

作者： Zhi Zheng Ronghua Li Qiang Zhang Xiaohua huang Wei Wang Shuling huang State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Key Laboratory of Disaster Prevention and Structural Safety of Ministry of EducationCollege of Civil Engineering and ArchitectureGuangxi UniversityNanning 530004China Key Laboratory of Ministry of Education on Safe Mining of Deep Metal Mines Northeastern UniversityShenyang 110819China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower ResearchBeijing 100038China Key Laboratory of Ministry of Education for Geomechanics and Embankment Engineering Hohai UniversityNanjing 210098China Key Laboratory of Geotechnical Mechanics and Engineering of Ministry of Water Resources Yangtze River Scientific Research InstituteWuhan 430010China

The deep surrounding rock is usually in the true triaxial stress state,and previous constitutive models based on the understanding of uniaxial and conventional triaxial test results have difficulty characterizing the degradation and fracture process of rock ductile–brittle failure under true triaxial stress ***,this study conducted a series of true triaxial tests to obtain the understanding of the ductile–brittle behaviour of rock,and then combined the test results and the Mogi–Coulomb strength criterion,and proposed calculation methods for the elastic modulus E,cohesion c and internal friction angle u and the evolution functions of E,c and u of rock under true triaxial *** the decreasing of the minimum principal stress r3 or increasing of the intermediate principal stress r2,the marble post-peak stress drop rate gradually increases,the ductility gradually weakens,and the brittleness significantly *** calculation method and evolution function of rock E,c and u under true triaxial stress were proposed.E decreased at first and then tended to remain stable with the increasing of equivalent plastic strain increment dep.c and u slowly increased at first and then rapidly *** a method of parameter degradation rate to realize post-peak stress drop rate to reflect the ductile–brittle characteristics,a new three-dimensional ductile–brittle deterioration mechanical model(3DBDM)was *** proposed model can accurately characterize the influence of r2 and r3 on mechanical parameters,the ductile–brittle behaviour of rock under true triaxial stresses,and the asymmetric failure characteristics of surrounding rock after excavation of deep underground *** proposed model can be reduced to elastic–perfectly plastic,elastic–brittle,cohesion weakening friction strengthening(CWFS),Mohr–Coulomb,and Drucker–Prager models.

关键词： True triaxial stress Post-peak characteristics 3D deterioration model Elastic modulus evolution Cohesion and friction angle evolution

In situ direct reprogramming of astrocytes to neurons via polypyrimidine tract-binding protein 1 knockdown in a mouse model of ischemic stroke

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

neural Regeneration Research 2024年第10期19卷 2240-2248页

作者： Meng Yuan Yao Tang Tianwen huang Lining Ke En huang Key Laboratory of Brain Aging and neurodegenerative Diseases of Fujian Province Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Human Anatomy School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Scientific Research Center School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Department of neurology Fujian Medical University Union HospitalFuzhouFujian ProvinceChina Fujian Key Laboratory of Vascular Aging Fujian Medical UniversityFuzhouFujian ProvinceChina

In situ direct reprogramming technology can directly convert endogenous glial cells into functional neurons in vivo for central nervous system repair. Polypyrimidine tract-binding protein 1(PTB) knockdown has been shown to reprogram astrocytes to functional neurons in situ. In this study, we used AAV-PHP.e B-GFAP-sh PTB to knockdown PTB in a mouse model of ischemic stroke induced by endothelin-1, and investigated the effects of GFAP-sh PTB-mediated direct reprogramming to neurons. Our results showed that in the mouse model of ischemic stroke, PTB knockdown effectively reprogrammed GFAP-positive cells to neurons in ischemic foci, restored neural tissue structure, reduced inflammatory response, and improved behavioral function. These findings validate the effectiveness of in situ transdifferentiation of astrocytes, and suggest that the approach may be a promising strategy for stroke treatment.

关键词： astrocyte in situ direct reprogramming ischemic stroke miR-30 based shRnA neuron polypyrimidine tract-binding protein 1 transdifferentiation

Quantifying the Tension between Cosmological Models and JWST Red Candidate Massive Galaxies

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第4期24卷 1-6页

作者： Jun-Chao Wang Zhi-Qi huang Lu huang Jianqi Liu School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Guangdong-Hong Kong-Macao Greater Bay Area Zhuhai519082China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China

We develop a Python tool to estimate the tail distribution of the number of dark matter halos beyond a mass threshold and in a given volume in a *** code is based on the extended Press-Schechter model and is computationally efficient,typically taking a few seconds on a personal laptop for a given set of cosmological *** high efficiency of the code allows a quick estimation of the tension between cosmological models and the red candidate massive galaxies released by the James Webb Space Telescope,as well as scanning the theory space with the Markov Chain Monte Carlo *** an example application,we use the tool to study the cosmological implication of the candidate galaxies presented in Labbéet *** standard Λcold dark matter(ΛCDM)model is well consistent with the data if the star formation efficiency can reach~0.3 at high *** a low star formation efficiency ε~0.1,theΛCDM model is disfavored at~2σ-3σconfidence level.

关键词： (cosmology:)cosmological parameters Galaxy:abundances Galaxy:formation

Associations of daily sedentary behavior,physical activity,and sleep with irritable bowel syndrome:A prospective analysis of 362,193 participants

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第1期13卷 72-80页

作者： Xu Gao Sifan Tian ninghao huang Gang Sun Tao huang Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100191China Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100191China Department of Gastroenterology and Hepatology First Medical Center of People's Liberation Army General HospitalBeijing 100853China

Background:Irritable bowel syndrome(IBS)substantially affects quality of life and requires early *** study aimed to elucidate the relationships between IBS and daily behaviors,including sedentary behavior(SB),physical activity(PA),and *** particular,it seeks to identify healthy behaviors to reduce IBS risk,which previous studies have rarely ***:Daily behaviors were retrieved from self-reported data of 362,193 eligible UK Biobank *** cases were determined by self-report or health care data according to RomeⅣ***:A total of 345,388 participants were IBS-free at baseline,during a median follow-up of 8.45 years,19,885 incident IBS cases were *** examined individually,SB and shorter(≤7 h/day)or longer(>7 h/day)sleep duration were each positively associated with increased IBS risk,and PA was associated with lower IBS *** isotemporal substitution model suggested that replacing SB with other activities could provide further protective effects against IBS *** people sleeping≤7 h/day,replacing 1 h of SB with equivalent light PA,vigorous PA,or sleep was associated with 8.1%(95%confidence interval(95%CI):0.901-0.937),5.8%(95%CI:0.896-0.991),and 9.2%(95%CI:0.885-0.932)reduced IBS risk,*** people sleeping>7 h/day,light and vigorous PA were associated with a 4.8%(95%CI:0.926-0.978)and a 12.0%(95%CI:0.815-0.949)lower IBS risk,*** benefits were mostly independent of genetic risk for ***:SB and unhealthy sleep duration are risk factors for IBS.A promising way to mitigate IBS risk for individuals sleeping≤7 h/day and for those sleeping>7 h/day appears to be by replacing SB with adequate sleep or vigorous PA,respectively,regardless of the genetic predisposition of IBS.

关键词： Irritable bowel syndrome Isotemporal substitution model Physical activity Sedentary behavior Sleep