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Mindfulness training in medical education as a means to improve resilience,empathy,and mental health in the medical profession

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World Journal of Psychiatry 2024年第4期14卷 489-493页

作者： Edison Iglesias de oliveira Vidal Luiz Fernando alvarenga Ribeiro Marco Antonio de Carvalho-Filho Fernanda Bono Fukushima Internal Medicine Department Botucatu Medical SchoolSao Paulo State University(UNESP)Botucatu 18618-687SPBrazil Wenckebach Institute for Education and Training LEARN-Lifelong LearningEducation and Assessment Research NetworkUniversity Medical Center GroningenGroningen 9713AVGroningenNetherlands Assertiva Mindfulness Botucatu 18603-970SPBrazil Surgical Specialties and Anesthesiology Department Botucatu Medical SchoolSão Paulo State University(UNESP)Botucatu 18618-687SPBrazil

The high rates of depression,burnout,and increased risk of suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our *** contend that this crisis coupled with the inadequate acquisition of interpersonal skills during medical education results from the interaction between a challenging environment and the mental capital of ***,we posit that mindfulness-based practices are instrumental for the development of major components of mental capital,such as resilience,flexibility of mind,and learning skills,while also serving as a pathway to enhance empathy,compassion,self-awareness,conflict resolution,and relational ***,the evidence base supporting the effectiveness of mindfulness-based interventions has been increasing over the years,and a growing number of medical schools have already integrated mindfulness into their *** we acknowledge that mindfulness is not a panacea for all educational and mental health problems in this field,we argue that there is currently an unprecedented opportunity to gather momentum,spread and study mindfulness-based programs in medical schools around the world as a way to address some longstanding shortcomings of the medical profession and the health and educational systems upon which it is rooted.

关键词： Mindfulness Medical education Mental capital Mental health Medical students Resilience

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Molecular and Chemical Analyses of Cyanobacterial Blooms in Tropical Lagoons from Southeast Brazil

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Journal of Water Resource and Protection 2015年第1期7卷 50-71页

作者： Luciana Mecatti Elias Maria Estela Silva-Stenico danillo oliveira alvarenga Janaina Rigonato Marli Fátima Fiore Simone Possedente de Lira Department of Exact Sciences Escola Superior de Agricultura “Luiz de Queiroz” Universidade de Sao Paulo Piracicaba Brazil Centro de Energia Nuclear na Agricultura Universidade de Sao Paulo Piracicaba Brazil

The genetic diversity and the potential toxicity of bloom-forming cyanobacteria were studied in four lagoons located in the state of Sao Paulo (Campinas, Limeira and Piracicaba cities). Bloom samples were collected on the water surface and cyanobacterial communities were evaluated using DGGE fingerprinting and 16S rDNA clone library. The amplification of genes encoding secondary metabolites such as microcystin (mcy), anatoxin (ana), cylindrospermopsin (cyr), saxitoxin (sxt), cyanopeptolin (mcn) and aeruginosin (aer) was performed and their production analyzed by LC-MS. The comparison of DGGE banding pattern among the different water samples suggested that some operational taxonomic units (OTUs) in these locations were predominant over others. The 16S rDNA clone libraries sequences matched with nine different known cyanobacterial genera available in NCBI, identified as Anabaena, Brasilonema, Cylindrospermopsis, Limnococcus, Microcystis, Nostoc, Pseudanabaena, Synechococcus and Woronichinia. The lagoons ESALQ2, Taquaral and Limeira had more than 80% of the cyanobacterial community assigned to the genus Microcystis. Genes encoding aeruginosin, cyanopeptolin and microcystin synthetases and saxitoxin synthase were amplified, and LC-MS/MS confirmed the production of aeruginosin, cyanopeptolin and microcystin. Rapid and sensitive methods for the detection of these secondary metabolites, especially toxins, using chemical and molecular tools together, can be used for a faster diagnostic of toxic cyanobacterial blooms.

关键词： Cyanobacteria Bloom Cyanotoxins Lagoons Microcystis

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Cerium alleviates drought-induced stress in Phaseolus vulgaris

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Journal of Rare Earths 2020年第3期38卷 324-331页

作者： Olívia Graziela Gelioli Salgado Jéssica Cristina Teodoro Joyce Pereira alvarenga Cynthia de oliveira Teotonio Soares de Carvalho Débora Domiciano Paulo Eduardo Ribeiro Marchiori Luiz Roberto Guimaraes Guilherme Department of Soil Science Federal University of LavrasCP 3037Campus UFLALavras37200-000Brazil Department of Biology Federal University of LavrasCP 3037Campus UFLALavras37200-000Brazil

Extreme drought events are expected to be one of the main challenges for tropical agriculture and,consequently,for global food *** this reason,it is urgent to develop strategies to increase water use efficiency,as well as to increase crops’ ability to cope with *** rare earth elements(REEs) are known to alleviate damages in plants under abiotic stresses,we hypothesized that addition of Ce^3+to nutrient solution would promote the growth of common bean,especially under simulated drought *** test this hypothesis,we conducted an experiment evaluating the effect of six Ce^3+concentrations on the development and physiological traits of common bean grown in nutrient solution under normal condition and under induced drought stress,caused by the addition of polyethylene glycol6000 to the nutrient *** results show that Ce^3+alleviates water stress in common bean plants,increasing their survival rate and *** addition,Ce^3+application increases photosynthesis rate,chlorophyll content and water use efficiency under water ***,we observe no significant effect of Ce^3+on plants growing under normal ***,Ce3+seems to be a promising attenuator of drought stress for common bean.

关键词： Water stress Polyethylene glycol Rare earth elements Cerium nitrate Mitigation Common bean

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Hepatobiliary phases in magnetic resonance imaging using liverspecific contrast for focal lesions in clinical practice

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World Journal of Hepatology 2022年第7期14卷 1459-1469页

作者： Daniel alvarenga Fernandes Eduardo Andreazza Dal Lago Felipe Aguera Oliver Bruna Melo Coelho Loureiro Daniel Lahan Martins Thiago José Penachim Ricardo Hoelz de oliveira Barros José de ArimatéiaBatista Araújo Filho Larissa Bastos Eloy da Costa Áurea Maria oliveira da Silva Elaine Cristina de Ataíde Ilka de Fátima Santana Ferreira Boin Nelson Marcio Gomes Caserta Department of Radiology School of Medical SciencesUniversity of Campinas-UNICAMPCampinas 13083-888São PauloBrazi Department of Radiology Medical SchoolSão Paulo State University-UNESPBotucatu 18618-970São PauloBrazil Instituto de Radiologia Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo-InRad/HC-FMUSPSão Paulo 05403-010SPBrazil Department of Radiology Sírio-Libanês HospitalSão Paulo 05652-900SPBrazil Department of Pathology School of Medical SciencesUniversity of Campinas-UNICAMPCampinas 13083-888São PauloBrazil Liver Transplant Unit Department of SurgerySchool of Medical SciencesUniversity of Campinas-UNICAMPCampinas 13083-888São PauloBrazil

BACKGROUND Challenging lesions,difficult to diagnose through non-invasive methods,constitute an important emotional burden for each patient regarding a still uncertain diagnosis(malignant x benign).In addition,from a therapeutic and prognostic point of view,delay in a definitive diagnosis can lead to worse *** of the main innovative trends currently is the use of molecular and functional methods to *** liver-specific contrast agents havebeen developed and studied in recent years to improve the performance of liver magnetic resonance imaging(MRI).More recently,one of the contrast agents introduced in clinical practice is gadoxetic acid(gadoxetate disodium).AIM To demonstrate the value of the hepatobiliary phases using gadoxetic acid in MRI for the characterization of focal liver lesions(FLL)in clinical *** Overall,302 Lesions were studied in 136 patients who underwent MRI exams using gadoxetic acid for the assessment of *** radiologists independently reviewed the MRI exams using four stages,and categorized them on a 6-point scale,from 0(lesion not detected)to 5(definitely malignant).The stages were:stage 1-images without contrast,stage 2-addition of dynamic phases after contrast(analogous to usual extracellular contrasts),stage 3-addition of hepatobiliary phase after 10 min(HBP 10’),stage 4-hepatobiliary phase after 20 min(HBP 20’)in addition to stage *** The interobserver agreement was high(weighted Kappa coefficient:0.81-1)at all stages in the characterization of benign and malignant *** diagnostic weighted accuracy(Az)was 0.80 in stage 1 and was increased to 0.90 in stage *** of the hepatobiliary phase increased Az to 0.98 in stage 3,which was also 0.98 in stage *** The hepatobiliary sequences improve diagnostic *** growing potential in the era of precision medicine,the improvement and dissemination of the method among medical specialties can bring benefits in the management of patients w

关键词： Liver Liver neoplasms Liver transplantation Medical oncology Diagnostic imaging Magnetic resonance imaging

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Gas Exchange and Production of Photosynthetic Pigments of Piper aduncumL. Grown at Different Irradiances

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American Journal of Plant Sciences 2013年第12期4卷 114-121页

作者： Fernanda Ventorim Pacheco Helbert Rezende de oliveira Silveira Amauri Alves alvarenga Ivan Caldeira Almeida alvarenga José Eduardo Brasil Pereira Pinto Jean Marcel Sousa Lira Departamento de Agricultura Geral UFLA-Universidade Federal de Lavras Lavras Brazil Setor de Fisiologia Vegetal Departamento de Biologia UFLA-Universidade Federal de Lavras Lavras Brasil

The species Piper aduncum is a plant with great economic potential, because the essential oil has antimicrobial activity and insecticides. Thus, as the light directly affects photosynthesis process, the present study evaluated the gas exchanges’ variables and photosynthetic pigments’ production of P. aduncum grown under different irradiances. Treatments consisted in environments with 100%, 70% and 50% of irradiance and environments with colored nets (red and blue). After 150 days of culture, photosynthetic activity (A), stomatal conductance (gs) transpiration rate (E), internal CO2 concentration (Ci), deficit vapor pressure (DVP), leaf temperature, concentration of internal/external CO2 (Ci/Ca), carboxylation efficiency (A/Ci) and efficiency water use (A/E) were evaluated. Pigments chlorophyll a, b, carotenoids, total and chlorophyll a/b ratio were also measured. From the observed data, it can be concluded that the species Piper aduncun developed various mechanisms for adaptation to different irradiance conditions. Moreover, it can be inferred that their photosynthetic process is more efficient and has larger spectral intensities of light, with higher efficiency photosynthetic when grown under 70% and 100% of radiation.

关键词： Long Pepper Color Nets Chlorophyll Luminosity Ecoambients

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Nutritional Quality of Olives and Olive oil Produced in the Serra Da Mantiqueira from Brazil

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Agricultural Sciences 2017年第7期8卷 518-526页

作者： Angelo Alberico alvarenga Joyce Ludimila da Cruz Adelson Francisco de oliveira Luiz Fernando de oliveira da Silva Emerson Dias Goncalves Paulo Marcio Norberto Researchers/Scholarship BIP FAPEMIG/EPAMIG SulBrazil Scholarship PIBIC FAPEMIG/EPAMIG SulBrazil

The olive tree (Olea europaea L.) is one of the oldest fruits grown by man. Its fruit can be processed into olive oil or treated properly and serve directly for the in natura consumption in the form of olives. Extracted from the olive, the olive oil is highly valued in the market, for its nutritional benefits and also for its unique and delicate flavor. Brazil is the second largest importer of olive oil in the world, but technology is already available and the expansion of the crop has been taking place in the south-southeast regions, where the climate is favorable, in order to serve this market. The objective of this work was to evaluate the physical and chemical qualities of the olives and characterize, sensorially and chemically, olive oils from different olive cultivars planted in the Region of Serra da Mantiqueira. The olives and olive oils produced from the cultivars Arbequina, Arbosana, Grapolo 541, Koroneiki and Maria da Fé were evaluated at the EPAMIG Experimental Field of Maria da Fé, Minas Gerais, and Brazil. In the first experiment the olives harvested in February of 2015 were analyzed in terms of weight, volume, transverse and longitudinal diameter of the fruit and the lump and the relation of the olive/lump and the chemical (protein, lipid, moisture and ashes). In the second experiment the olives were processed by the grinding, beating and centrifugation method to obtain the oils. The olive oils were analyzed for acidity, peroxide index and absorbance in the ultraviolet region at 274 nm, 270 nm, 266 nm and 232 nm. After this characterization the olive oils produced in the Serra da Mantiqueira were then submitted to sensorial analysis. The results were submitted to analysis of variance and the means were compared by the Tukey test at 5% of probability. The interpretation of the data from the sensorial analysis was done using the software sensomaker. Differences were observed between olives and olive oils produced by different cultivars in the Serra da M

关键词： Diet Health Cooking

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Influence of Photoperiod over Morphometric and Hematological Parameters of Juvenile Piracanjubas （Brycon orbygnianus）

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Journal of Agricultural Science and Technology(B) 2016年第5期6卷 350-359页

作者： Monica Rodrigues Ferreira Machado] Eliane Aparecida de Andrade Estefania de Souza Andrade Daniella Aparecida de Jesus Paula Julia alvarenga oliveira Adriano Carvalho Costa Ana Paula Peconick Luis David Solis Murgas Department of Biological Science Federal University of Goias (UFG) Campus Cidade Universitaria CEP 75801-615 JataiGoias Brazil Department of Veterinary Medicine Cdmpus Universitario Federal University of Lavras (UFLA) Lavras Minas Gerais CEP3 7200-000 Brazil Department of Animal Science Federal Institute of Rio Verde (IFR V) Rio Verde Goias CEP 75901-970 Brazil

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Composition of Cachacas Produced from Five Varieties of Sugarcane and the Correlation of the Presence of Dhurrin in the Cane with That of Ethyl Carbamate in the Product

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American Journal of Plant Sciences 2019年第2期10卷 339-350页

作者： Francielli D’Carlos Cravo Wilder Douglas Santiago Allan da Silva Lunguinho Richard Bispo Barbosa Renan Elan da Silva oliveira Gabriela Fontes alvarenga Stephano Daniel Santos Rafaella Hilda Zaniti Souza Ellen Cristina de Souza Katia Julia de Almeida Josefina Aparecida de Souza David Lee Nelson Maria das Gracas Cardoso Department of Food Science Federal University of LavrasC.P.LavrasMinas GeraisBrazil Department of Chemistry Federal University of LavrasC.P.LavrasMinas GeraisBrazil Pro-Reitoria de Pesquisa e Pos-Graduacao Federal University of Vales de Jequitinhonha and MucuriDiamantinaMGBrazil

The present work sought to characterize the cyanogenic glycoside dhurrin in five sugarcane varieties and to determine its possible relationship with the formation of ethyl carbamate in cachaca. For each variety, methanol, ethyl acetate and hexane extracts were prepared and submitted to thin layer chromatography. Chromatographic spots were revealed with iodine vapors. The physical and chemical parameters of the spirits produced from the five different varieties of sugar cane and by different production processes were within the legal limits. Although not exceeding the limit for ethyl carbamate, a significant variation in the final concentration of this compound was observed for each sample analyzed. The Rf values for the dhurrin standard and for the sugarcane variety SP 83-2847 were equal, similar to those for SP 80-3280 and CTC 11 and different from the Rf values for the RB 86-7515 and IAC 86-2480 samples.

关键词： Cachaca Ethyl Carbamate Quality Glycosides Cyanide Dhurrin

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Chemical Composition and Allelopathic Activity of the Essential Oil from Callistemon viminalis(Myrtaceae)Blossoms on Lettuce(Lactuca sativa L.)Seedlings

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American Journal of Plant Sciences 2014年第24期5卷 3551-3557页

作者： Christiane Maria de oliveira Maria das Gracas Cardoso Ana Cristina da Silva Figueiredo Maria Laene Moreira de Carvalho Cintia alvarenga Santos Fraga de Miranda Luiz Roberto Marques Albuquerque David Lee Nelson Marcos de Souza Gomes Lucilene Fernandes Silva Juliana de Andrade Santiago Maria Luisa Teixeira Rafaela Magalhaes Brandao Department of Chemistry Federal University of LavrasLavrasBrazil Centro de Biotecnologia Vegetal/IBB Departamento de Biologia VegetalFaculdade de Ciencias de LisboaUniversidade de LisboaLisbonPortugal Department of Agriculture Federal University of LavrasLavrasBrazil Federal University of Valleys Jequitinhonha and Mucuri DiamantinaBrazil

The extraction of essential oils was performed by using the technique of hydrodistillation modified Clevenger apparatus, identification and quantification of the constituents was achieved by Gas Chromatography coupled to Mass Spectrometry, and Gas Chromatography equipped with a flame ionization detector. Assessment of allelopathic activity was evaluated with the use of the method that assesses the direct contact of essential oils on germination and vigor of lettuce seeds. The major constituents that characterize the essential oil from the flowers of Callistemon viminalis were 1, 8-cineole, α-pinene and limonene at concentrations of 66.9%, 16.0% and 10.0%, respectively. The essential oil presented allelopathic activity at intensities that varied proportionately to the concentration of the essential oil, with a reduction in the percentage of germination and the germination speed index (GSI) of lettuce seeds and in the dry mass and length of shoots and roots of lettuce seedlings.

关键词： Biological Activity Myrtaceae Allelopathy

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Chemical Composition and Allelopathic Activity of Parthenium hysterophorusand Ambrosia polystachyaWeeds Essential Oils

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American Journal of Plant Sciences 2014年第9期5卷 1248-1257页

作者： Cíntia alvarenga S. F. de Miranda Maria das G. Cardoso Maria Laene M. de Carvalho Ana Cristina S. Figueiredo David L. Nelson Christiane M. de oliveira Marcos de S. Gomes Juliana de Andrade Josefina A. de Souza Luiz R. Marques de Albuquerque Department of Agricuture Federal University of Lavras Lavras Brazil Department of Chemistry Federal University of Lavras Lavras Brazil Federal University of the Jequitinhonha and Mucuri Valleys Diamantina Brazil Universidade de Lisboa Faculdade de Ciências de Lis-boa DBV Instituto de Biotecnologia e Bioengenharia Centro de Biotecnologia Vegetal C2 Campo Grande Lisboa Portugal

The volatile constituents of the essential oils from leaves from the weed plants Parthenium hysterophorus and Ambrosia polystachya were identified and quantified by GLC-MS and GLC. Allelopathic activities were determined by methods that evaluated the volatile effects and the direct application of these essential oils on the seed germination and seedling vigor of lettuce. We identified 27 compounds in the essential oil from P. hysterophorus, and the main constituents were germacrene-D (35.9%), trans-β-ocimene (8.5%) and β-myrcene (7.6%). In the essential oil from A. polystachya, 40 constituents were identified and the principal compounds were germacrene-D (29.3%), trans-β-ocimene (13.6%) and β-caryophyllene (9.8%). In both methods, the essential oil from A. polystachya presented a greater potential for reducing seed germination and seedling vigor in lettuce than the essential oil from P. hysterophorus, and this activity might be attributed to its higher content of monoterpenes.

关键词： Volatile Oils Allelopathy Asteraceae

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