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Psychological, social, and sexual challenges affecting men receiving male infertility treatment: a systematic review and implications for clinical care

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Asian journal of Andrology 2023年第4期25卷 448-453页

作者： Winston Wu justin La Kathryn M Schubach daniel Lantsberg Darren j Katz Department of Urology Western HealthSt AlbansVIC 3021Australia Department of Urology Kaiser Permanente San Rafael Medical CenterSan RafaelCA 94903USA Men’s Health Melbourne MelbourneVIC 3000Australia Reproductive Services Unit The Royal Women’s HospitalParkvilleVIC 3052Australia Melbourne IVF East MelbourneVIC 3002Australia Department of Surgery Western PrecinctUniversity of MelbourneParkvilleVIC 3010Australia

In recent years, social research surrounding the consequences of infertility has increasingly focused on the male perspective;however, a gap exists in the understanding of men’s experiences of male infertility treatment. This review aims to synthesize theexisting evidence concerning the psychological, social, and sexual burden of male infertility treatment on men, as well as patientneeds during clinical care. A systematic search identified 12 studies that are diverse in design, setting, and methods. Psychologicalevaluations have found that urological surgery may have a lasting impact on infertility-specific stress, and treatment failure canlead to feelings of depression, grief, and inadequacy. Men tended to have an avoidant coping mechanism throughout fertilitytreatment, and their self-esteem, relationship quality, and sexual functions can be tied to outcomes of treatment. Partner bonds canbe strengthened by mutual support and enhanced communication;couple separation, however, has been noted as a predominantreason for discontinuing male infertility treatment and may be associated with difficult circumstances surrounding severe maleinfertility. Surgical treatments can affect the sexual functioning of infertile men;however, the impact of testicular sperm extractionoutcomes appears to be psychologically driven whereas the improvements after microsurgical varicocelectomy are only evident inhypogonadal men. Clinically, there is a need for better inclusion, communication, education, and resource provision, to addressreported issues of marginalization and uncertainty in men. Routine psychosocial screening in cases of severe male infertility andfollow-up in cases of surgical treatment failure are likely beneficial.

关键词： male infertility male infertility treatment patient experience patient-centered care psychosocial sexual

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Urban invaders are not bold risk-takers: a study of 3 invasive lizards in Southern California

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Current Zoology 2020年第6期66卷 657-665页

作者： Breanna j.Putman Gregory B.Pauly daniel T.Blumstein Department of Ecology and Evolutionary Biology University of CaliforniaLos AngelesCA90095-1606USA Department of Herpetology and Urban Nature Research Center Natural History Museum of Los Angeles County900 Exposition BoulevardLos AngelesCA90007USA Department of Biology California State UniversitySan BernardinoCA 92407USA

Biological invasions threaten biodiversity worldwide,and therefore,understanding the traits of successful invaders could mitigate their *** comm only invasive species do well in disturbed habitats,such as urban environments,and their abilities to effectively respond to disturbarices could con tribute to their ***,there are non invasive species that also do well in disturbed *** question remains whether urban invaders behave differently in urban environments than noninvaders,which could suggest an"urban-exploiting"*** Southern California,the co-occurrence of in vasive Italia n wall lizards Pod arc is siculus,brown anoles Anolis sagrei,and green anoles ***,and native western fence lizards Sceloporus occidentalis offers an opportunity to test whether invasives exhibit consistent differences in risk-taking within human-altered habitats compared with a native *** predicted that invasive lizards would exhibit more bold behavior by having shorter flight-initiation distances(FIDs)and by being found farther from a refuge(behaviors that would presumably maximize foraging in low-risk environments).Invasive populations had similar or longer FIDs,but were consistently found at distances closer to a ***,invasive lizards in urban habitats were not bolder than a native *** on nearby refuges might help species successfully invade urban habitats,and if a general pattern,may pose an added challenge in detecting or eliminating them.

关键词： antipredator boldness escape behavior invasion reptile urban ecology

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Cytokines from the pig conceptus:roles in conceptus development in pigs

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journal of Animal Science and Biotechnology 2015年第2期6卷 130-141页

作者： Rodney D Geisert Matthew C Lucy jeffrey j Whyte jason W Ross daniel j Mathew Animal Sciences Research Center University of Missouri Department of Animal Science Iowa State University

Establishment of pregnancy in pigs involves maintaining progesterone secretion from the corpora lutea in addition to regulating a sensitive interplay between the maternal immune system and attachment of the rapidly expanding trophoblast for nutrient absorption. The peri-implantation period of rapid trophoblastic elongation followed by attachment to the maternal uterine endometrium is critical for establishing a sufficient placental-uterine interface for subsequent nutrient transport for fetal survival to term, but is also marked by the required conceptus release of factors involved with stimulating uterine secretion of histotroph and modulation of the maternal immune system. Many endometrial genes activated by the conceptus secretory factors stimulate a tightly controlled proinflammatory response within the uterus. A number of the cytokines released by the elongating conceptuses stimulate inducible transcription factors such as nuclear factor kappa B （NFKB） potentially regulating the maternal uterine proinflammatory and immune response. This review will establish the current knowledge for the role of conceptus cytokine production and release in early development and establishment of pregnancy in the pig.

关键词： Cytokines Embryo development Porcine conceptus Pregnancy Prostaglandins uterus

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Sperm retrieval and intracytoplasmic sperm injection outcomes in men with cystic fibrosis disease versus congenital bilateral absence of the vas deferens

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Asian journal of Andrology 2021年第2期23卷 140-145页

作者： j Abram McBride Taylor P Kohn daniel j Mazur Larry I Lipshultz R Matthew Coward Scott Department of Urology Baylor College of MedicineHoustonTX 77030USA Department of Urology UNC School of MedicineChapel HillNC 27599USA UNC Fertility RaleighNC 27617USA

Recent data suggest that cystic fibrosis transmembrane conductance regulator(CFTR)gene alterations negatively impact male fertility beyond *** sought to compare gene alterations,sperm retrieval rates,and intracytoplasmic sperm injection(ICSI)outcomes among men with cystic fibrosis(CF)disease and congenital bilateral absence of the vas deferens(CBAVD)*** retrospectively evaluated all men who underwent surgical sperm retrieval at two academic,high-volume andrology centers from 2010 to *** men with documented CFTR alterations and obstructive azoospermia from either CBAVD or CF were *** between groups for CFTR abnormality,sperm retrieval,and ICSI outcomes were statistically ***,39 patients were included with 10 in the CF and 29 in the CBAVD *** sperm retrieval rates were significantly lower in the CF group for sperm concentration(14.8×10^(6)ml^(-1)vs 61.4×10^(6)ml^(−1),P=0.02)and total motile sperm count(2.9 million vs 11.4 million,P=0.01).This difference was only predicted by homozygous delta F508 CFTR mutations(P<0.05).The CF group also demonstrated a significantly higher rate of rescue testicular sperm extraction(70.0%vs 27.6%,P<0.03)and lower fertilization rate with ICSI(32.5%vs 68.9%,P<0.01).In conclusion,those with CF demonstrated lower sperm quality,greater difficulty with sperm retrieval,and worse ICSI outcomes compared with CBAVD-only *** delta F508 CFTR mutations appear to significantly impair spermatogenesis and sperm function.

关键词： congenital bilateral absence of the vas deferens cystic fibrosis intracytoplasmic sperm injection outcomes male infertility obstructive azoospermia

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The price of protection:a defensive endosymbiont impairs nymph growth in the bird cherry-oat aphid,Rhopalosiphum padi

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Insect Science 2020年第1期27卷 69-85页

作者： daniel j.Leyboume jorunn I.B.Bos Tracy A.Valentine Alison j.Karley Division of Plant Sciences School of Life SciencesUniversity of DundeeDundeeU K Cell and Molecular Sciences the James Hutton InstituteInvergowrieDundeeUK Ecological Sciences the James Hutton InstituteInvergowrieDundeeUK

Bacterial endosymbionts have enabled aphids to adapt to a range of stressors,but their effects in many aphid species remain to be *** bird cherry-oat aphid,Rhopalosiphum padi(Linnaeus),is an important pest of cereals worldwide and has been reported to form symbiotic associations with Serratia symbiotica and Sitobion miscanthi L-type symbiont endobacteria,although the resulting aphid phenotype has not been *** study presents the first report of *** infection with the facultative bacterial endosymbiont Hamiltonella *** of *** were sampled from populations in Eastern Scotland,UK,and shown to represent seven *** genotypes based on the size of polymorphic microsatellite markers;two of these genotypes harbored *** parasitism assays,survival of ***-infected nymphs following attack by the parasitoid wasp Aphidius colemani(Viereck)was 5 fold higher than for uninfected *** genotype was a major determinant of aphid performance on two Hordeum species,a modern cultivar of barley *** and a wild relative ***,although aphids infected with *** showed 16%lower nymph mass gain on the partially resistant wild relative compared with uninfected *** findings suggest that deploying resistance traits in barley will favor the fittest *** genotypes,but symbiontinfected individuals will be favored when parasitoids are abundant,although these aphids will not achieve optimal performance on a poor quality host plant.

关键词： cereal aphid Hamiltonella defensa Hordeum spontaneum Hordeum vulgare symbiosis

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Human-Swarm-Teaming Transparency and Trust Architecture

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IEEE/CAA journal of Automatica Sinica 2021年第7期8卷 1281-1295页

作者： Adam j.Hepworth daniel P.Baxter Aya Hussein Kate j.Yaxley Essam Debie Hussein A.Abbass the School of Engineering and Information Technology University of New South WalesCanberraNew South Wales 2612Australia

Transparency is a widely used but poorly defined term within the explainable artificial intelligence *** is due,in part,to the lack of an agreed definition and the overlap between the connected—sometimes used synonymously—concepts of interpretability and *** assert that transparency is the overarching concept,with the tenets of interpretability,explainability,and predictability *** draw on a portfolio of definitions for each of these distinct concepts to propose a human-swarm-teaming transparency and trust architecture(HST3-Architecture).The architecture reinforces transparency as a key contributor towards situation awareness,and consequently as an enabler for effective trustworthy human-swarm teaming(HST).

关键词： Artificial intelligence explainability human-swarm teaming(HST) interpretability predictability swarm shepherding transparency.

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Fatty acid content in epididymal fluid and spermatozoa during sperm maturation in dogs

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journal of Animal Science and Biotechnology 2017年第3期8卷 574-581页

作者： daniel S.Ramos Angrimani Marcilio Nichi joāo Diego A.Losano Cristina F.Lucio Gisele A.Lima Veiga Márcia V.M.junqueira franco Camila I.Vannucchi Department of Animal Reproduction School of Veterinary Medicine and Animal Science University of Sāo Paulo Rua Prof. Orlando Marques de Paiva 87 Sāo Paulo 05508-270 Brazil Department of Internal Medicine Division of Nutrition University of Sāo Paulo Av. Bandeirantes 3900 - 14040-040 Ribeirāo Preto. Brazil

Background： During sperm maturation, there is a reorganization of fatty acids from plasmatic membrane of the spermatozoa, which allows higher membrane integrity and acquisition of sperm motility. However, the fatty acid profile during sperm maturation remains unclear in dogs. Thus, the aim of this study was to identify the fatty acids from the epididymal spermatozoa and plasma during the sperm maturation, and observed changes in the motility and plasmatic membrane parameters. Twenty one adult dogs were used, subsequently to bilateral orchiectomy and epididymal storage, sperm samples were collected from the different segments of the epididymis. Samples were evaluated for conventional microscopy, computer-assisted motility analysis, sperm plasma membrane permeability and the fatty acid analysis（lipids were extracted, transmethylated and analyzed by chromatography）.Results： Caput and corpus sperm showed lower values for the motility variables evaluated and plasmatic membrane integrity, indicating different levels of the fatty acids organization. Saturated, monounsaturated and polyunsaturated fatty acids were in higher concentrations in the spermatozoa from epididymis cauda. Highlighting the presence of caprylic, stearic and docosahexaenoic ***： These findings demonstrate the influence of the fatty acid profile during sperm maturation, assigning physical and chemical changes in sperm cells, essential for fertilization.

关键词： Dogs Epididymis Fatty acids Sperm maturation

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Techniques in Wrist and Hand Arthroscopy 1

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2007年

作者： David j. Slutsky daniel j. Nagle

ISBN: (纸本)9780443066979

Enhance your skills in arthroscopic surgery - an increasingly important aspect of the treatment of a variety of traumatic and degenerative ailments of the hand. Leaders in the field describe their preferred approaches in step-by-step detail - emphasizing what outcomes you can expect - and also examine the diagnostic advantages of this precise technique. A bonus DVD features video clips of the procedures described in the book, enabling you to see these performed in real time!

关键词： Hand jointssurgery

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Nonsingularity of Grain-like cascade FSRs via semi-tensor product

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Science China(Information Sciences) 2018年第1期61卷 58-69页

作者： jianquan LU Meilin LI Yang LIU daniel W.C.HO jrgen KURTHS School of Mathematics Southeast University College of Mathematics Physics and Information Engineering Zhejiang Normal University Department of Mathematics City University of Hong Kong Potsdam Institute for Climate Impact Research

In this paper, Grain-like cascade feedback shift registers(FSRs) are regarded as two Boolean networks(BNs), and the semi-tensor product(STP) of the matrices is used to convert the Grain-like cascade FSRs into an equivalent linear equation. Based on the STP, a novel method is proposed herein to investigate the nonsingularity of Grain-like cascade FSRs. First, we investigate the property of the state transition matrix of Grain-like cascade FSRs. We then propose their sufficient and necessary nonsingularity condition. Next,we regard the Grain-like cascade FSRs as Boolean control networks(BCNs) and further provide a sufficient condition of their nonsingularity. Finally, two examples are provided to illustrate the results obtained in this paper.

关键词： Grain-like cascade FSRs Boolean control networks Boolean networks semi-tensor product nonsingularity

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Evolution of interventional endoscopic ultrasound

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Gastroenterology Report 2023年第1期11卷 131-139页

作者： Mark j.Radlinski daniel S.Strand Vanessa M.Shami Division of Gastroenterology and Hepatology University of VirginiaCharlottesvilleVAUSA

Endoscopic ultrasound(EUS)has become an indispensable modality for the assessment of the gastrointestinal tract and adjacent structures since its origin in the *** the development of the linear echoendoscope,EUS has evolved from a purely diagnostic modality to a sophisticated tool for intervention,with numerous luminal,pancreaticobiliary,and hepatic ***,these applications may be subdivided into three categories:transluminal drainage or access procedures,injection therapy,and EUS-guided liver *** drainage or access procedures include management of pancreatic fluid collection,EUS-guided biliary drainage,EUS-guided bile duct drainage,EUS-guided pancreatic duct drainage,and enteral anastomosis *** therapies include therapeutic EUS-guided injections for management of malignancies accessible by ***-guided liver applications include EUS-guided liver biopsy,EUS-guided portal pressure gradient measurement,and EUS-guided vascular *** this review,we discuss the origins of each of these EUS applications,evolution of techniques leading to the current status,and future directions of EUS-guided interventional therapy.

关键词： endoscopic ultrasound interventional endoscopic ultrasound biliary drainage gastrojejunostomy pancreatic pseudocyst drainage

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