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Sm-Nd systematics of metaultramafic-mafic rocks from the Arroio Grande Ophiolite(Brazil): Insights on the evolution of the South Adamastor paleo-ocean

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Geoscience Frontiers 2020年第6期11卷 2287-2296页

作者： Rodrigo Chaves Ramos Edinei Koester daniel triboli vieira Programa de Pòs-Graduação Em Geociências Instituto de GeociênciasUniversidade Federal Do Rio Grande Do Sul.PO Box 1500191501-970Porto AlegreRSBrazil Departamento de Geologia Universidade Federal Do Rio Grande Do Sul.Bento Gonçalves Avenue950091540-000Porto AlegreRSBrazil

In this contribution we present new insights on the evolution of the Dom Feliciano Belt,southernmost Mantiqueira Province,integrating new whole-rock Sm-Nd isotopic data for the Arroio Grande Ophiolite(Punta del Este Terrane,Brazil/Uruguay border)with previously published bulk-rock and isotope geochemistry of the South Adamastor paleo-ocean metamafic rocks located in Uruguay(Paso del Dragon Complex,Punta del Este Terrane)and Namibia(Chameis Subterrane,Marmora Terrane,Gariep Belt).For the regional geology,the new data corroborate previous hypothesis and demonstrate the depleted mantle features of the amphibolites and metagabbros of the studied *** Arroio Grande Ophiolite rocks are compared with its Uruguayan and Namibian counterparts,demonstrating their isotopic and geochemical similarities and differences,and the backarc affinity of the South Adamastor *** MORB-affinity amphibolites from the Arroio Grande Ophiolite-Paso del Dragon Complex are,so far,the most juvenile rocks in the eastern sector of the Dom Feliciano Belt,yielding εNd(640)Ma)between+7.3 and+9,and high 147Sm/144Nd(>0.169)and 143Nd/144Nd(640 Ma)ratios(0.51219-0.51229).The South Adamastor is interpreted in this paper as an internal back-arc ocean,with limited lateral extension,opened at around 750-650 Ma as the result of the closure of the older Charrua-Goianide paleoocean during the Brasiliano/Pan-African orogenic cycle and final configuration of the West Gondwana paleocontinent.

关键词： West Gondwana Brasiliano orogenic cycle Adamastor ocean

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Characterization of soil fauna under the influence of mercury atmospheric deposition in Atlantic Forest, Rio de Janeiro, Brazil

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Journal of Environmental Sciences 2015年第6期27卷 217-227页

作者： Andressa Cristhy Buch Maria Elizabeth Fernandes Correia daniel Cabral Teixeira Emmanoel vieira Silva-Filho Departamento de Geoquímica Universidade Federal Fluminense Embrapa Agrobiologia BR 465 km 7

The increasing levels of mercury（Hg） found in the atmosphere arising from anthropogenic sources, have been the object of great concern in the past two decades in industrialized countries. Brazil is the seventh country with the highest rate of mercury in the *** major input of Hg to ecosystems is through atmospheric deposition（wet and dry）, being transported in the atmosphere over large distances. The forest biomes are of strong importance in the atmosphere/soil cycling of elemental Hg through foliar uptake and subsequent transference to the soil through litter, playing an important role as sink of this element. Soil microarthropods are keys to understanding the soil ecosystem, and for such purpose were characterized by the soil fauna of two Units of Forest Conservation of the state of the Rio de Janeiro, inwhich one of the areas suffer quite interference from petrochemicals and industrial anthropogenic activities and other area almost exempts of these perturbations. The results showed that soil and litter of the Atlantic Forest in Brazil tend to stock high mercury concentrations, which could affect the abundance and richness of soil fauna, endangering its biodiversity and thereby the functioning of ecosystems.

关键词： Biodiversity Litter Microarthropods Soil Trace-element

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Effects of blood flow restriction without additional exercise on strength reductions and muscular atrophy following immobilization:A systematic review

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Journal of Sport and Health Science 2020年第2期9卷 152-159页

作者： Mikhail Santos Cerqueira Jose Diego Sales Do Nascimento daniel Germano Maciel Jean Artur Mendonca Barboza Wouber Herickson De Brito vieira Department of Physical Therapy Laboratory of Muscle PerformanceFederal University of Rio Grande do NorteNatalRio Grande do Norte 59072-970Brazil Department of Physical Therapy Neuromuscular Performance Analysis LaboratoryFederal University of Rio Grande do NorteNatalRio Grande do Norte 59072-970Brazil

Purpose:To investigate whether blood flow restriction(BFR) without concomitant exercise mitigated strength reduction and atrophy of thigh muscles in subjects under immobilization for lower ***:The following databases were searched:PubMed,CINAHL,PEDro,Web of Science,Central,and ***:The search identified 3 eligible studies,and the total sample in the identified studies consisted of 38 *** and isometric torque of the knee flexors and extensors was examined in 2 ***-sectional area of thigh muscles was evaluated in 1 study,and thigh girth was measured in 2 *** BFR protocol was 5 sets of 5 min of occlusion and 3 min of free flow,twice daily for approximately 2 *** a whole,the included studies indicate that BFR without exercise is able to minimize strength reduction and muscular atrophy after *** is crucial to emphasize,however,that the included studies showed a high risk of bias,especially regarding allocation concealment,blinding of outcome assessment,intention-to-treat analyses,and group similarity at ***:Although potentially useful,the high risk of bias presented by original stodies limits the indication of BFR without concomitant exercise as an effective countermeasure against strength reduction and atrophy mediated by immobilization.

关键词： Disuse Hypoxia Ischemia Muscle wasting Rehabilitation

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Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis:Useless or useful?-A literature review

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World Journal of Gastroenterology 2021年第27期27卷 4413-4428页

作者： Diogo Alpuim Costa Carla Espiney Amaro Ana Nunes Joana Santos Cardoso Pedro Modas daniel Isabel Rosa João vieira Branco Department of Haematology and Oncology CUF OncologiaLisboa 1998-018Portugal Centro de Medicina Subaquática e Hiperbárica(CMSH) Portuguese NavyLisboa 1649-020Portugal Centro de Investigação Naval(CINAV) Portuguese NavyBase Naval do AlfeiteAlmada 2810-001Portugal OVA Medical School Faculdade de Ciências MédicasLisboa 1169-056Portugal Department of Otorhinolaryngology Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal Department of Gastroenterology Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal Department of Vascular Surgery Centro Hospitalar Universitário de Lisboa CentralHospital de Santa MartaLisboa 1169-024Portugal Department of Intensive Care Unit Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal Department of General Surgery Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal

Radiotherapy(RT)is the backbone of multimodality treatment of more than half of cancer *** new modern RT techniques,late complications may occur such as radiation proctitis(RP).The natural history of RP is *** symptoms may resolve spontaneously or require conservative *** the other hand,for similar and uncomplicated clinical contexts,symptoms may persist and can even be refractory to the progressive increase in treatment *** the last decades,an enormous therapeutic armamentarium has been considered in RP,including hyperbaric oxygen therapy(HBOT).Currently,the evidence regarding the impact of HBOT on RP and its benefits is *** prospective and randomised studies are necessary to validate HBOT’s effectiveness in the‘real world’clinical *** article reviewed the relevant literature on pathophysiology,clinical presentation,different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT.

关键词： Radiation proctitis Radiation proctopathy Radiotherapy Radio-induced lesion Late radiation tissue injury Delayed radiation injury Late sequelae Hyperbaric oxygen therapy Hyperbaric oxygen Review

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Edible Coatings Based on Apple Pectin,Cellulose Nanocrystals,and Essential Oil of Lemongrass:Improving the Quality and Shelf Life of Strawberries(Fragaria Ananassa)

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Journal of Renewable Materials 2019年第1期7卷 73-87页

作者： Ingrid Souza vieira da Silva Natália Soares Prado Patrícia Gontijo de Melo Danilo Campion Arantes Mara Zeni Andrade Harumi Otaguro daniel Pasquini Instituto de Química Universidade Federal de UberlândiaCampus Santa MônicaAv.João Naves deÁvila2121Uberlândia-MG38400-902Brazil Instituto Federal do Triângulo Mineiro Campus Uberaba Rua João Batista Ribeiro4000Uberaba-MG38064-790Brazil Departamento de Ciências Naturais(DCNAT) Universidade Federal de São João Del-ReiPraça D.Helvécio74São João Del-Rei-MG36301-160Brazil Universidade de Caxias do Sul Rua Francisco Getúlio Vargas1130Caxias do Sul-RS95070-970Brazil

In this work,nine different types of edible coating based on pectin,cellulose nanocrystals,glycerol,and essential oil of lemongrass were prepared and used to coat strawberries with a film formed directly on the surface of the coated *** effects of the different edible coatings on refrigerated fruits in terms of weight loss,titratable acidity,total soluble solids,pH,and anthocyanin content was evaluated after 2 days,4 days,6 days,and 8 days of *** of the edible coatings reduced the weight loss of the coated strawberries and the anthocyanin *** total soluble solids content of or uncoated fruit increase more markedly than that of coated *** contrast,pH was maintained for both coated and uncoated *** edible coatings were effective in minimizing of the weight loss,without worsening the physical chemistry *** treatments T5 and T9 presented the best results.

关键词： Strawberry edible coating cellulose nanocrystals pectin shelf life

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High aluminum concentration and initial establishment of Handroanthus impetiginosus : clues about an Al non-resistant species in Brazilian Cerrado

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Journal of Forestry Research 2020年第6期31卷 2075-2082页

作者： Ane Marcela das Chagas Mendon ca Jean Marcel Sousa Lira Ana Luiza de Oliveira Vilela daniel Amorim vieira Nayara Cristina de Melo Joao Paulo Rodrigues Alves Delfi no Barbosa Programa de Pós-Graduacao em Fisiologia Vegetal Departamento de BiologiaUniversidade Federal de LavrasLavrasMG 37200-000Brazil Programa de Pós-Graduacao em Ciências Ambientais Instituto de Ciências ExatasUniversidade Federal de AlfenasAlfenasMG 37130-001Brazil Programa de Pós-Graduacao em Fitotecnia Departamento de AgriculturaUniversidade Federal de LavrasLavrasMG 37200-000Brazil Instituto Federal de Educacao Ciência e Tecnologia do Pará BelémPA 66093-020Brazil

Cerrado soils are acidic and nutrient-poor,with high content of solubilized Al 3+.Plants growing in these conditions may display adaptations to cope with high aluminum concentrations especially during early developmental *** investigated leaf nutritional status,and photosynthetic and growth characteristics during the initial establishment of Handroanthus impetiginosus(*** Dc.)Mattos,a secondary tree species distributed in the Brazilian *** goal was to understand leaf-level traits related to diff erent aluminum *** plants were cultivated in four diff erent aluminum sulfate concentrations:0,1,2,and 4 mM Al,for 40 *** performed analyses of growth,leaf gas exchange,chloroplast pigment content,and leaf mineral *** observed a linear increase of Al leaf content as a function of Al concentration in the nutrient *** grown in 1 mM Al showed a remarkable increase of K leaf content,net photosynthesis,stomatal conductance,and transpiration,while in 4 mM Al there were reductions of N,P,and K contents,gas exchange characteristics,and *** did not have mechanisms of avoidance,compartmentalization,or resistance to high Al ***,this species showed a hormetic response,with low Al concentrations stimulating and high Al concentrations inhibiting plant responses.

关键词： Hormesis Low Al concentration Al toxicity Cerrado species Carbon assimilation

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Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population

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Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 330-335页

作者： Fabiola Rabelo Jose Tadeu Stefano Ana Mercedes Cavaleiro Rodrigo vieira Costa Lima daniel Ferraz de Campos Mazo Flair Jose Carrilho Maria Lúcia Correa-Giannellac Claudia P.Oliveiraa Departamento de Gastroenterologia Faculdade de Medicina FMUSPUniversidade de Sao PauloSao PauloSPBrazil Hospital das Clinicas HCFMUSP Departamento de GastroenterologiaLIM07Faculdade de MedicinaUniversidade de Sao PauloSao PauloSPBrazil Laboratório de Carboidratos e Radioimunensaio LIM18Hospital das Clinicas HCFMUSP(LIM07)Faculdade de MedicinaUniversidade de Sao PauloSao PauloBrazil Programa de Pos-Graduacao em Medicina Universidade Nove de Julho(UNINOVE)Sao PauloBrazil

Background: Oxidative stress has been implicated in the progression of severe forms of non-alcoholic fatty liver disease(NAFLD). NADPH oxidase produces reactive oxygen species. In the present study, we investigated for the first time two single nucleotide polymorphisms(SNPs) in the regulatory region of genes encoding NADPH oxidase 4(NOX4) and p22 phox(CYBA) in ***: A total of 207 biopsy-proven NAFLD patients [simple steatosis(n = 27); nonalcoholic steatohepatitis(NASH)(n = 180)] were evaluated. Genomic DNA was extracted from peripheral blood cells, and polymorphisms in CYBA(unregistered) and NOX4(rs3017887) were determined by direct sequencing of ***: Associations of CYBA-675 T/A with high-density lipoprotein(HDL)(TT vs TA vs AA; P < 0.01) and triglycerides(TGL)(TT vs XA; P < 0.01) were observed only in NASH patients. For polymorphisms in the NOX4 gene, NOX4(rs3017887) CA + AA genotypes was significant associated with alanine aminotransferase(ALT)(CA + AA vs CC; P = 0.02). However, there was no association of SNPs in the CYBA and NOX4 genes encoding the NADPH oxidase system proteins and the presence of NASH. Regarding the clinical results, it was observed that the most advanced degrees of fibrosis occurred in patients diagnosed with type 2 diabetes mellitus(66.9% vs 37.5%, P < 0.01) and those who were more obese(32.2 vs 29.0 kg/m2,P < 0.01). In addition, serum glucose and insulin levels increased significantly in the presence of ***: There were associations between the presence of the allele A in the NOX4 SNP and a higher concentration of ALT in the NAFLD population; between the presence of the AA genotype in the polymorphism of the CYBA-675 T/A CYBA gene and a higher level of TGL and lower HDL in NASH patients. The presence of metabolic syndrome was associated with advanced degrees of fibrosis in NAFLD patients.

关键词： Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Genetic polymorphism Metabolic syndrome

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Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents

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World Journal of Gastroenterology 2009年第4期15卷 473-477页

作者： Raquel Rocha Helma Pinchemel Cotrim Almir Galvo vieira Bitencourt daniel Batista Valente Barbosa Adméia Souza Santos Alessandro de Moura Almeida Bruno Cunha Isabel Guimares Postgraduate Course in Medicine and Health Federal University of BahiaSchool of Medicine Federal University of Bahia School of Medicine NASH Project University Hospital Professor Edgard SantosFederal University of Bahia

AIM： To evaluate the prevalence and clinical characteristics of Nonalcoholic fatty liver disease （NAFLD） among asymptomatic Brazilian adolescents. METHODS： Transversal observational study included asymptomatic adolescents with central obesity from private and public schools in Salvador-Bahia, northeastern Brazil. The children answered a questionnaire that in- cluded age, gender, race, and medical history, and were submitted to a complete physical exam and abdominal ultrasound. Biochemical exams included： ALT, AST, GGT, C reactive protein （CRP）, fasting glucose, insulin, cholesterol and triglycerides. Criteria for NAFLD included： the presence of steatosis in ultrasound and/or high level of ALT, negative or occasional historic of intake of alcohol （4 140 g/wk）, negative investigation for hepatitis A, B, C, auto-immune hepatitis, Wilson disease and ***： From October, 2005 to October, 2006, the study included 1801 subjects between 11 and 18 years of age and a mean age of 13.7± 2.0 years. One hun- dred ninety-nine had central obesity. The prevalence of NAFLD was 2.3%, most of whom were male and white. Insulin resistance （IR） was observed in 22.9% of them and had positive correlations with ALT and GGT （P 〈 0.05）. Elevated CRP was observed in 6.9% of the cases; however, it was not associated with WC, IR or liver enzymes. CONCLUSION： The prevalence of NAFLD in Brazilian adolescents was low. The ethnicity may have influence this frequency in the population studied, which had a large proportion of African descendents.

关键词： Nonalcoholic fatty liver disease Insulinresistance Central obesity Ethnicity Adolescents

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Fatty liver disease in severe obese patients:Diagnostic value of abdominal ultrasound

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World Journal of Gastroenterology 2008年第9期14卷 1415-1418页

作者： Alessandro de Moura Almeida Helma Pinchemel Cotrim daniel Batista Valente Barbosa Luciana Gordilho Matteoni de Athayde Adimeia Souza Santos Almir Galvo vieira Bitencourt Luiz Antonio Rodrigues de Freitas Adriano Rios Erivaldo Alves Faculdade de Medicina da Bahia Universidade Federal da Bahia SalvadorBahia 41830-020Brasil Faculdade de Medicina da Bahia Universidade Federal da BahiaSalvadorBahia 41830-020Brasil Faculdade de Medicina da Bahia Universidade Federal da Bahia SalvadorBahia 41830-020Brasil Faculdade de Medicina da Bahia Universidade Federal da BahiaSalvadorBahia 41830-020 Brasil Núcleo de Cirurgia da Obesidade SalvadorBahia 41830-020Brasil

AIM:To evaluate the sensitivity and specificity of abdominal ultrasound (US) for the diagnosis of hepatic steatosis in severe obese subjects and its relation to histological grade of steatosis. METHODS: A consecutive series of obese patients, who underwent bariatric surgery from October 2004 to May 2005, was selected. Ultrasonography was performed in all patients as part of routine preoperative time and an intraoperative wedge biopsy was obtained at the beginning of the bariatric surgery. The US and histological findings of steatosis were compared, considering histology as the gold standard. RESULTS: The study included 105 patients. The mean age was 37.2 ± 10.6 years and 75.2% were female. The histological prevalence of steatosis was 89.5%. The sensitivity and specificity of US in the diagnosis of hepatic steatosis were, respectively, 64.9% (95% CI: 54.9-74.3) and 90.9% (95% CI: 57.1-99.5). The positive predictive value and negative predictive value were, respectively, 98.4% (95% CI: 90.2-99.9) and 23.3% (95% CI: 12.3-39.0). The presence of steatosis onUS was associated to advanced grades of steatosis on histology (P = 0.016). CONCLUSION: Preoperative abdominal US in our series has not shown to be an accurate method for the diagnosis of hepatic steatosis in severe obese patients. Until another non-invasive method demonstrates better sensitivity and specificity values, histological evaluation may be recommended to these patients undergoing bariatric surgery.

关键词： Bariatric surgery Obesity Hepatic steatosis Abdominal ultrasound diagnosis Fatty liver

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Green tea polyphenols inhibit testosterone production in rat Leydig cells

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Asian Journal of Andrology 2009年第3期11卷 362-370页

作者： Marina S. Figueiroa Juliany S. B. Cesar vieira Disleide S. Leite Ruben C. O. Andrade Filho Fabiano Ferreira Patricia S. Gouveia daniel P. Udrisar Maria I. Wanderley Department of Physiology and Pharmacology Federal University of Pernambuco 50607-901 Recife PE Brazil

This study investigated the acute effects of green tea extract （GTE） and its polyphenol constituents, （-）-epigallocatechin-3-gallate （EGCG） and （-）-epicatechin （EC）, on basal and stimulated testosterone production by rat Leydig cells in vitro. Leydig cells purified in a Percoll gradient were incubated for 3 h with GTE, EGCG or EC and the testosterone precursor androstenedione, in the presence or absence of either protein kinase A （PKA） or protein kinase C （PKC） activators. The reversibility of the effect was studied by pretreating cells for 15 min with GTE or EGCG, allowing them to recover for 1 h and challenging them for 2 h with human chorionic gonadotropin （hCG）, luteinizing hormone releasing hormone （LHRH）, 22（R）-hydroxycholesterol or androstenedione. GTE and EGCG, but not EC, inhibited both basal and kinase-stimulated testosterone production. Under the pretreatment conditions, the inhibitory effect of the higher concentration of GTE/EGCG on hCG/LHRH-stimulated or 22（R）- hydroxycholesterol-induced testosterone production was maintained, whereas androstenedione-supported testosterone production returned to control levels. At the lower concentration of GTE/EGCG, the inhibitory effect of these polyphenols on 22（R）-hydroxycholesterol-supported testosterone production was reversed. The inhibitory effects of GTE may be explained by the action of its principal component, EGCG, and the presence of a gallate group in its structure seems important for its high efficacy in inhibiting testosterone production. The mechanisms underlying the effects of GTE and EGCG involve the inhibition of the PKA/PKC signalling pathways, as well as the inhibition of P450 side-chain cleavage enzyme and 17β-hydroxysteroid dehydrogenase function.

关键词： green tea polyphenols Leydig cells protein kinase A protein kinase C testosterone

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