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Modelling of dust emissions induced by flow over stockpiles and through packed beds

Particuology 2021年第6期19卷 55-63页

作者： daniel schulz Nadja Schwindt Eberhard Schmidt Harald Kruggel-Emden Technische Universitat Berlin Chair of Mechanical Process Engineering and Solids ProcessingEmst-Reuter-Platz 1D-10587 BerlinGermany University of Wuppertal Institute of Particle TechnologyRainer-Gruenter-StrGeb.FFD-42119 WuppertalGermany

Dust emissions during storage of non-moving bulk materials are studied with a numerical *** model relies on a contact-model-free Discrete Element Method(DEM)to model the bulk particle-fluid interaction and the dust removal coupled with Computational Fluid Dynamics(CFD)to model the gas and the dust phase in a multiphase ***,two storage scenarios are considered:a flown through packed bed and a flown over *** the first,the performed simulations reveal that the dust discharge can be correlated with the passing fluid pressure *** the second,a parameter study of factors influencing the dust emissions is *** parameters discussed are the stockpile size,the gas velocity,the slope angle,the particle diameter and the shape of the stockpile,taking into account conical and truncated conical *** release correlations are obtained for both scenarios,which reflect very well the obtained numerical results.

关键词： Computational Fluid Dynamics(CFD) Discrete Element Method(DEM) Dust release correlations Stockpile emissions Packed bed emissions

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Dissecting the Heat Stress Response in Chlamydomonas by Pharmaceutical and RNAi Approaches Reveals Conserved and Novel Aspects

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Molecular Plant 2013年第6期6卷 1795-1813页

作者： Stefan Schmollinger Miriam schulz-Raffelt daniela Strenkert daniel Veyel Olivier Vallon Michael Schroda Molekulare Biotechnologie und Systembiologie TU Kaiserslautern PauI-Ehrlich-Str. 23 D-67663 Kaiserslautern Germany Max-Planck-lnstitut for Ilolekulare Pflanzenphysiologie Am MQhlenberg 1 D-14476 Potsdam-Golm Germany CEA-CNRS-Universite Aix Marseille Institut de Biolog~e Environnementale et Biotechnologie UMR 7265 CEA (:adarache F-13108 Saint-Paul-lez-DuranceFrance Institut de Biologie Physico-Chimique UMR 7141 CNRS/Universite Pierre et Marie Curie F-75005 Paris France

To study how conserved fundamental concepts of the heat stress response （HSR） are in photosynthetic eukaryotes, we applied pharmaceutical and antisense/amiRNA approaches to the unicellular green alga Chlamydomonas reinhardtii. The Chlamydomonas HSR appears to be triggered by the accumulation of unfolded proteins, as it was induced at ambient temperatures by feeding cells with the arginine analog canavanine. The protein kinase inhibitor staurosporine strongly retarded the HSR, demonstrating the importance of phosphorylation during activation of the HSR also in Chlamydomonas. While the removal of extracellular calcium by the application of EGTA and BAPTA inhibited the HSR in moss and higher plants, only the addition of BAPTA, but not of EGTA, retarded the HSR and impaired thermotoler- ance in Chlamydomonas. The addition of cycloheximide, an inhibitor of cytosolic protein synthesis, abolished the attenu- ation of the HSR, indicating that protein synthesis is necessary to restore proteostasis. HSP90 inhibitors induced a stress response when added at ambient conditions and retarded attenuation of the HSR at elevated temperatures. In addition, we detected a direct physical interaction between cytosolic HSP90A/HSP70A and heat shock factor 1, but surprisingly this interaction persisted after the onset of stress. Finally, the expression of antisense constructs targeting chloroplast HSP70B resulted in a delay of the cell＇s entire HSR, thus suggesting the existence of a retrograde stress signaling cascade that is desensitized in HSP7OB-antisense strains.

关键词： heat shock factor unfolded protein response heat stress response inhibitor feeding Chlamydomonas rein-hardtii HSP90 HSP70 protein folding calcium geldanamycin canavanine.

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Enhanced thermal stability of organic solar cells comprising ternary D-D-A bulk-heterojunctions

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npj Flexible Electronics 2017年第1期1卷 92-99页

作者： Dominik Landerer Adrian Mertens Dieter Freis Robert Droll Tobias Leonhard Alexander Deniz schulz daniel Bahro Alexander Colsmann Light Technology Institute Karlsruhe Institute of Technology(KIT)Engesserstrasse 1376131 KarlsruheGermany Material Research Center for Energy Systems(MZE) Karlsruhe Institute of Technology(KIT)Strasse am Forum 776131 KarlsruheGermany

Ternary absorber blends have recently been identified as promising concepts to spectrally broaden the absorption of organic bulkheterojunction solar cells and hence to improve their power conversion *** this work,we demonstrate that D-D-A ternary blends comprising two donor polymers and the acceptor PC61BM can also significantly enhance the thermal stability of the solar *** harsh thermal stress at 120°C for 2 h,the ternary solar cells show only a minor relative deterioration of 10%.Whereas the polymer/fullerene blend PTB7-Th:PC61BM is rather unstable under these conditions,its degradation was efficiently suppressed by incorporating the near infrared-absorbing polymer PDTP–*** ellipsometry investigations and an effective medium analysis of the ternary absorber blend revealed that the domain conformation in presence of PDTP–DFBT remains stable whereas the domain conformation changes in its *** ternary PTB7-Th:PDTP–DFBT:PC61BM solar cells yield thermally stable power conversion efficiencies of up to 6%.

关键词： ternary stability absorber

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Reconstruction of extremity long bone defects with vascularized fibula bone grafts

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Plastic and Aesthetic Research 2019年第6期6卷 1-12页

作者： Corinne Wee DanieI Ruter Steven SchuIz Geoffroy Sisk JuIie West Scott TintIe Ian VaIerio Division of Plastic and Reconstructive Surgery in the Department of Surgery Case Western Reserve UniversityClevelandOH 44106USA Division of Plastic and Reconstructive Surgery in the Department of Surgery Albany Medical CollegeAlbanyNY 12208USA Department of Plastic and Reconstructive Surgery The Ohio State UniversityColumbusOH 43212USA Department of Orthopaedic Surgery Walter Reed National Military Medical CenterBethesdaMD 20889USA

Aim: Composite tissue defects encompassing bone and/or isolated bony defects can pose a surgical challenge;however, their reconstruction is critical for successful functional limb salvage. These cases become increasingly problematic as secondary defects, following multiple nonvascularized grafting attempts resulting in complex bony nonunion. Herein, our experience utilizing fibula vascularized bone grafts (VBGs) for bone restoration will be presented to demonstrate their utility in a variety of reconstructions for limb salvage. Methods: This is a case series describing a series of vascularized fibula grafts for extremity reconstruction performed by a single academic surgeon over multiple institutions in seven years. Results: Twenty-seven (27) total VBGs met inclusion criteria and underwent reconstruction for traumatic (16), oncologic (6) and chronic degenerative (5) etiologies. Bony union was achieved in 26 of 27 cases. Conclusion: The decision-making process for bony reconstruction in these scenarios is difficult and multivariable. Fibula VBGs can provide a single-stage solution for autologous bony and soft tissue replacement of large or complex bone defects and can often be superior options compared with non-vascularized bone grafts or non-bone internal fixation techniques. Their osteogenic potential is unmatched by allogenic or synthetic substitutions. These benefits are evident in a variety of clinical settings such as pediatrics, oncology and trauma.

关键词： Vascularized bone vascularized bone grafts composite extremity defect restoration bone reconstruction free tissue transfer microsurgery

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