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Can sexual selection and disassortative mating contribute to the maintenance of a shell color polymorphism in an inter- tidal marine snail？

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Current Zoology 2012年第3期58卷 463-474页

作者： Emilio ROLALVAREZ Maria SAURA Angel E DIZ Marfa JOSE RIVAS MargaALVAREZ Beatriz CORTES Alicia de COO daniel ESTEVEZ Laura iglesias Departamento de Bioqufmica Genetica e Inmunologfa Facultad de Biologfa Universidad de Vigo Campus de Vigo 36310 VigoSpain

Littorina fabalis is an intertidal snail commonly living on the brown algae Fucus vesiculosus and showing frequent shell-color polymorphisms in the wild. The evolutionary mechanism underlying this polymorphism is currently unknown. Shell color variation was studied in mated and non-mated specimens of this species from different microareas in one locality from NW Spain, in order to estimate sexual selection and assortative mating that may （still） be operating in this population. The analyses across microareas allowed us to investigate frequency-dependent selection and assortative mating components, mechanisms that could maintain the polymorphism. The presence of shell scars caused by crab attacks, an environmental variable not related with sexual selection or assortative mating, was used as experimental control. This study provides new evidence of significant disas- sortative mating and some degree of sexual selection against some shell colors, supporting the results found 21 years ago in a similar study, i.e. in the same species and locality. The similarity of these estimates during the studied period suggests that this experimental approach is consistent and valid to be extended to other populations and organisms. In addition, sexual selection and assortative mating estimates did not change across microareas differing in shell color frequencies, suggesting than the polymor- phism can not be maintained by a frequency-dependent （sexual selection-based） mechanism. Our main hypothesis is that negative assortative mating could contribute to the maintenance of the polymorphism, perhaps by males showing distinct female color preferences when searching for mates [Current Zoology 58 （3）： 463-474, 2012].

关键词： Fitness estimate Mate choice Mate propensity Negative assortative mating Sexual selection Frequency-dependentselection

Erratum to:Carbon nanostructure morphology templates nanocomposites for phosphoproteomics

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Nano Research 2020年第2期13卷 596-596页

作者： Susy Piovesana daniel iglesias Manuel Melle-Franco Slavko Kralj Chiara Cavaliere Michele Melchionna Aldo Lagana Anna L.Capriotti Silvia Marchesan PiazzaleA.Moro 5 Dipartimento di ChimicaSapienza Universita di RomaRome 00185Italy Via L.Giorgieri 1 Dipartimento di Scienze Chimiche e FarmaceuticheUniversita di TriesteTrieste 34127Italy CICECO University ofAveiroAveiro 3810-193Portugal Jamova 39 Department for Materials SynthesisJozef Stefan InstituteLjubljana 1000Slovenia Via Monteroni Campus Ecotekne CNR NANOTECUniversity of ScdentoLecce 73100Italy

The fourth author’s name was unfortunately misspelled on the first page and the first page of the ESM. Instead of Susy Piovesana1, daniel iglesias2, Manuel Melle-Franco3, Slavo Kralj4, Chiara Cavaliere1, Michele Melchionna2, Aldo Laganà1,5, Anna L. Capriotti1 (✉), and Silvia Marchesan2 (✉) It should read Susy Piovesana1, daniel iglesias2, Manuel Melle-Franco3, Slavko Kralj4, Chiara Cavaliere1, Michele Melchionna2, Aldo Laganà1,5, Anna L. Capriotti1 (✉), and Silvia Marchesan2 (✉)

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Morpholino studies shed light on the signaling pathways regulating axon regeneration in lampreys

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Neural Regeneration Research 2022年第7期17卷 1475-1477页

作者： daniel Sobrido-Cameán Antón Barreiro-iglesias Department of Functional Biology Faculty of BiologyCIBUSUniversidade de Santiago de CompostelaSantiago de CompostelaA CoruñaSpain Department of Zoology University of CambridgeCambridgeUK

Lampreys are one of the most ancient extant vertebrates and they have become an animal model of interest for the study of spontaneous axon regeneration after a traumatic central nervous system *** to most mammals,lamp... 详细信息

关键词： traumatic regeneration injury

Gamma-aminobutyric acid(GABA) promotes recovery from spinal cord injury in lampreys: role of GABA receptors and perspective on the translation to mammals

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Neural Regeneration Research 2019年第10期14卷 1695-1696页

作者： daniel Romaus-Sanjurjo María Celina Rodicio Antón Barreiro-iglesias Department of Functional Biology CIBUS Faculty of BiologyUniversidade de Santiago de Compostela

In mammals, spinal cord injury (SCI) is a devastating event that can lead to a permanent loss of motor, sensory and autonomic functions below the site of injury. In the last years, the role of different neurotransmitter systems on regeneration and recovery from SCI has been deciphered. For example, studies in lampreys have shown that neurotransmitters play a key role in modulating the survival and regeneration of brainstem descending neurons after SCI (Romaus-Sanjurjo et al., 2018;Sobrido-Camean et al., 2018).

关键词： In mammals devastating event regeneration

Serotonin controls axon and neuronal regeneration in the nervous system:lessons from regenerating animal models

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Neural Regeneration Research 2018年第2期13卷 237-238页

作者： daniel sobrido-cameán maría celina rodicio antón barreiro-iglesias department of functional biology cibusfaculty of biologyuniversidade de santiago de compostelaa CorunaSpain

Traumatic brain injury （TBI） is a mechanical injury to brain tissue that leads to an impairment of function and a broad spectrum of symptoms and disabilities; often, it is followed by diffuse axonal injury, which causes denaturation of the white matter and axon retraction, leaving patients with severe brain damage or even in a persistent vegetative state.

关键词： AMP HT lessons from regenerating animal models Serotonin controls axon and neuronal regeneration in the nervous system TBI

Accuracy of endoscopic ultrasound-guided tissue acquisition in the evaluation of lymph nodes enlargement in the absence of on-site pathologist

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World Journal of Gastroenterology 2017年第31期23卷 5755-5763页

作者： Yung Ka Chin Julio iglesias-Garcia daniel de la Iglesia Jose Larino-Noia Ihab Abdulkader-Nallib Hector Lázare Susana Rebolledo Olmedo J Enrique Dominguez-Munoz Department of Gastroenterology and Hepatology University Hospital of Santiago de Compostela Health Research Institute of Santiago de Compostela (IDIS) University Hospital of Santiago de Compostela Department of Pathology University Hospital of Santiago de Compostela

To evaluate factors that influence the diagnostic accuracy of endoscopic ultrasound (EUS)-guided tissue acquisition for lymph node enlargement in the absence of an on-site pathologist. METHODSA retrospective analysis of patients who underwent EUS-guided tissue acquisition for the pathological diagnosis of lymph node enlargement between April 2012 and June 2015 is reported. Tissue acquisition was performed with both cytology and biopsy needles of different calibers. The variables evaluated were lymph node location and size, number of passes and type of needle used. Final diagnosis was based on surgical histopathology or, in non-operated cases, on EUS-guided tissue acquisition and imaging assessment with a minimum clinical follow-up of 6 mo. RESULTSDuring the study period, 168 lymph nodes with a median size of 20.3 mm (range 12.5-27) were sampled from 152 patients. Ninety lymph nodes (53.6%) were located at mediastinum, and 105 (62.5%) were acquired with biopsy needles. The final diagnosis was benign/reactive origin in 87 cases (51.8%), malignant in 65 cases (38.7%), and lymphoma in 16 cases (9.5%). The sensitivity, specificity, positive predictive value and negative predictive value for the detection of malignancy were 74.1%, 100%, 100% and 80.6%, respectively. The overall accuracy was 87.5% (95%CI: 81.7-91.7). No variables were independently associated with a correct final diagnosis according to the multivariate analysis. CONCLUSIONEUS-guided tissue acquisition is a highly accurate technique for assessing lymph node enlargement. None of the variables evaluated were associated with diagnostic accuracy.

关键词： Lymph node Endoscopic ultrasound Fine-needle aspiration Fine-needle biopsy Accuracy

Dystrophic Calcinosis in the Hands of a Patient with Rheumatoid Arthritis and Secundary Sjogren’s Syndrome

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Open Journal of Rheumatology and Autoimmune Diseases 2013年第1期3卷 56-58页

作者： daniel Jaramillo-Arroyave Gerardo Quintana Federico Rondon-Herrera Antonio iglesias-Gamarra Internal Medicine RheumatologyDepartment of Internal MedicineRheumatology UnitUniversidad Nacional de ColombiaBogotáColombia

Salts of calcium phosphate and inorganic phosphate are normally found in serum and extracellular fluids, balancing through poorly understood factors that prevent abnormal tissue deposition of these minerals. However, in those tissues that are injured, especially due to chronic inflammatory processes, a predisposition to the deposition of these minerals is developed, triggering what has been called Dystrophic Calcinosis (DC), common in different Connective Tissue Diseases (CTD), especially dermatomyositis and scleroderma, but there is no a frecuent association with diseases like Rheumatoid Arthritis (RA) and Sj?gren Syndrome (SS). We report a case of a female patient of 63 years old with RA and Secundary SS who presents with DC in the hands and no evidence of other connective tissue.

关键词： Dystrophic Calcinosis Rheumatoid Arthritis Sjogren Syndrome

Miniscrew appliances and their use in orthodontics

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Open Journal of Stomatology 2013年第1期3卷 103-108页

作者： Rocío Molina-Solana R. M. Yanez-Vico Alejandro iglesias-Linares daniel Torres-Lagares Enrique Solano-Reina Department of Stomatology University of SevilleSevilleSpain

Anchorage is an important factor in orthodontics and must be properly managed for a successful treatment outcome. Orthodontists have historically used many devices to prevent unwanted tooth movement. The use of miniscrews as a source of skeletal anchorage has become routine in present-day orthodontic practice. Skeletal anchorage opens up alternative treatments, to borderline surgery patients for example, who can now be treated by taking advantage of the biomechanical properties of miniscrews. Because they are bone-borne and provide excellent control over tooth movement in the three spatial planes of movement, mini-implants can be used to serve many purposes in addition to anchorage. Therefore, a variety of successful mini-implant appliances are explained in relation to the three planes of movement: sagittal, vertical, and transverse. The aim of this review is to illustrate the clinical versatility of miniscrews in the three spatial planes of malocclusion in orthodontic and orthopedic management and to define clinical guidelines for the selection, application and biomechanics of mini-implants.

关键词： Miniscrew Mini-implant Orthodontics Anchorage

Risk of gastrointestinal cancer in a symptomatic cohort after a complete colonoscopy:Role of faecal immunochemical test

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World Journal of Gastroenterology 2020年第1期26卷 70-85页

作者： Noel Pin-Vieito María J iglesias David Remedios Lorena Rodríguez-Alonso Francisco Rodriguez-Moranta VictoriaÁlvarez-Sánchez Fernando Fernández-Bañares Jaume Boadas Eva Martínez-Bauer Rafael Campo Luis Bujanda Ángel Ferrandez Virginia Piñol daniel Rodríguez-Alcalde Jordi Guardiola Joaquín Cubiella Gastroenterology Department Complexo Hospitalario Universitario de OurenseCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas(CIBERehd)Ourense 32005Spain Department of Gastroenterology and Hepatology University Hospital of Bellvitge-IDIBELLL'Hospitalet de LlobregatBarcelona 08907Spain.Ciber de Epidemiología y Salud Pública(CIBERESP)Spain Gastroenterology Department Complejo Hospitalario de PontevedraPontevedra 36001Spain Gastroenterology Department Hospital Universitari Mútua de TerrassaCIBERehdTerrassa 08221Spain Gastroenterology Department Consorci Sanitari de TerrassaTerrassa 08221Spain Gastroenterology Department Hospital de SabadellCorporacióSanitària Donostia Hospital Biodonostia InstituteUniversity of the Basque Country UPV/EHUCIBERehdSan Sebastian 20010Spain Servicio de Aparato Digestivo Hospital Clínico UniversitarioIIS AragónUniversity of ZaragozaCIBERehdZaragoza 50009Spain Gastroenterology Department Hospital Dr.Josep TruetaGirona 17007Spain Digestive Disease Section Hospital Universitario de MóstolesMadrid 28935Spain

BACKGROUND Faecal immunochemical test(FIT)has been recommended to assess symptomatic patients for colorectal cancer(CRC)***,some conditions could theoretically favour blood originating in proximal areas of the gastrointestinal tract passing through the colon unmetabolized.A positive FIT result could be related to other gastrointestinal cancers(GIC).AIM To assess the risk of GIC detection and related death in FIT-positive symptomatic patients(threshold 10μg Hb/g faeces)without *** Post hoc cohort analysis performed within two prospective diagnostic test studies evaluating the diagnostic accuracy of different FIT analytical systems for CRC and significant colonic lesion *** patients with gastrointestinal symptoms referred consecutively for colonoscopy from primary and secondary healthcare,underwent a quantitative FIT before undergoing a complete *** without CRC were divided into two groups(positive and negative FIT)using the threshold of 10μg Hb/g of faeces and data from follow-up were retrieved from electronic medical records of the public hospitals involved in the *** determined the cumulative risk of GIC,CRC and upper *** rate(HR)was calculated adjusted by age,sex and presence of significant colonic *** We included 2709 patients without CRC and a complete baseline colonoscopy,730(26.9%)with FIT≥10μgr Hb/*** a mean time of 45.5±20.0 mo,a GIC was detected in 57(2.1%)patients:An upper GIC in 35(1.3%)and a CRC in 14(0.5%).Thirty-six patients(1.3%)died due to GIC:22(0.8%)due to an upper GIC and 9(0.3%)due to ***-positive subjects showed a higher CRC risk(HR 3.8,95%CI:1.2-11.9)with no differences in GIC(HR 1.5,95%CI:0.8-2.7)or upper GIC risk(HR 1.0,95%CI:0.5-2.2).Patients with a positive FIT had only an increased risk of CRC-related death(HR 10.8,95%CI:2.1-57.1)and GIC-related death(HR 2.2,95%CI:1.1-4.3),with no differences in upper GIC-related death(HR 1.4,95%CI:0.6-3.3).An

关键词： Colonoscopy Colorectal cancer Faecal immunochemical test Gastric cancer Gastroesophageal cancer Gastrointestinal cancer Symptoms