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An NSQIP evaluation of practice patterns and outcomes following surgery for anorectal abscess and fistula in patients with and without Crohn’s disease

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Gastroenterology Report 2013年第1期1卷 58-63页

作者： Marlin Wayne Causey daniel Nelson Eric K.Johnson Justin Maykel Brad Davis David E.Rivadeneira Brad Champagne Scott R.Steele Department of Surgery Madigan Army Medical SystemMadigan Health SystemTacomaWA 98431USA

Background:Patients with Crohn’s disease(CD)are believed to have more aggressive anorectal abscess and fistula *** assessed the types of procedures performed and perioperative complications associated with the surgical management of anorectal abscess and fistula disease in patients with and without ***:The American College of Surgeons National Surgical Quality Improvement Program database(ACS-NSQIP,2005-2010)was used to calculate 30-day outcomes using regression modeling,accounting for demographics,comorbidities and surgical ***-9 codes for anorectal abscess or fistula were used for initial *** were then stratified,based on the presence or absence of underlying *** procedures included incision and drainage of abscesses,fistulotomy and seton *** fistulas were considered simple,while all others were classified as complex(-vaginal,-urethral and-vesical).Results:A total of 7,218 patients(mean age 45 years;64%male)met inclusion criteria,with underlying CD in 345(4.8%).CD patients were more likely to have a seton placed(9.9 vs 8.2%,P<0.001)and be on steroids(15.4 vs 4.3%,P<0.001).Thirty-seven percent of CD patients underwent local procedures,while 46%had a proctectomy and8%underwent *** was more common in those without underlying CD(16 vs 11%,P<0.001).The overall complication rate after local treatment was 4.9%,with no difference between patients with and without CD(7.7 vs 4.9%,P=0.144).This was not affected by fistula type-simple(7.9 vs 3.9%,P=0.194)vs complex(33 vs 7.1%,P=0.21)—or when stratified by wound(3.8 vs 2.4%;P=0.26)or systemic complications(3.8 vs 2.5%;P=0.53).Yet,complications following emergency procedures were higher in patients with CD(21.4 vs 5.9%,P=0.047).Factors significantly associated with increased complications were Crohn’s disease(OR=8.2),lack of functional independence(OR=2.0),pre-operative weight loss(OR=2.6)and pre-operative acute renal failure(OR=5.6).Steroids were al

关键词： National Surgical Quality Improvement Program(NSQIP) Crohn’s disease anorectal diseases anorectal abscess fistula-in-ano

A simple and efficient seed-based approach to induce callus production from B73 maize genotype

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American Journal of Molecular Biology 2012年第4期2卷 380-385页

作者： Simeon O.Kotchoni Pacome A.Noumavo Adolphe Adjanohoun daniel P.Russo John Dell’Angelo Emma W.Gachomo Lamine Baba-Moussa Department of Biology RutgersThe State University of New JerseyCamdenUSA Center for Computational and Integrative Biology(CCIB) The State University of New JerseyCamdenUSA Département de Biochimie et Biologie Cellulaire Universitéd’Abomey-CalaviCotonouBenin Centre de Recherches Agricoles Institut National des Recherches Agricoles du BeninAlladaBenin

The wild type maize genotype, B73, is not amenable for callus production and an efficient protocol for B73 maize callus induction has never been reported up-to-date. Scientific efforts in producing B73 maize callus using all known callus inducible media have been unsatisfactory. Here we developed and described an efficient protocol for callus induction from B73 maize seedlings. The protocol is based on well known callus inducible media CM4C where we have sequentially subtracted some chemical compounds and added some new compounds mediating cell proliferations. This newly described protocol was able to induce callus production in a wide range of crop species including rice and soybean. We found that cell proliferation factors, NAA (auxin analog) and 2,4 D (auxin influx carrier) were not only very crucial but required for positive B73 maize callus induction. The absence of one or the other will lead to the failure of B73 maize callus production. The well known CM4C callus induction composition lacks NAA. Our findings will advance genetic studies of maize mutants generated from B73 genotype background.

关键词： B73 Maize Genotype Soybean Callus CM4C Maize Protocol Rice NAA 2,4-D

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使纯水水质满足实验检测限要求

使纯水水质满足实验检测限要求

BCEIA2005分析仪器应用技术报告会

作者： Stephane Mabic Ichiro Kano daniel Darbouret 研究与开发实验室纯水部Millipore SASSt.Quentin-Yvelines

分析过程中的用水的水质会直接影响化学分析的可靠性。根据化学分析中灵敏度的要求,不同的分析需要使用不同纯度的水。本文就生产纯水的各种方法进行了回顾。需要注意的是,对于极度灵敏分析的用水,明显的污染往往来自实验室环境而并非...

分析过程中的用水的水质会直接影响化学分析的可靠性。根据化学分析中灵敏度的要求,不同的分析需要使用不同纯度的水。本文就生产纯水的各种方法进行了回顾。需要注意的是,对于极度灵敏分析的用水,明显的污染往往来自实验室环境而并非来自纯水系统本身。在这种情况下,纯水系统应该在洁净室条件下使用。

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微胶黏物的去除和第4代筛鼓

微胶黏物的去除和第4代筛鼓

Effects of aquatic exercise on depression and anxiety in ischemic stroke subjects

中国造纸学会第十五届学术年会

作者： Alain Lascar Frederic Vaulot daniel Parenteau Kadant Lamort ASA Kadant Black Clawson Inc.

2009年,Kadant发布的一项研究提出了小胶黏物的特性及去除对策,这种小胶黏物被称之为微胶黏物。基于纸厂调查和几个中试车间的试验,结论之一是微胶黏物的筛选效率低,而对于去除微胶黏物有些技术比其他技术更好。自早期的研究之后,第4代... 详细信息

2009年,Kadant发布的一项研究提出了小胶黏物的特性及去除对策,这种小胶黏物被称之为微胶黏物。基于纸厂调查和几个中试车间的试验,结论之一是微胶黏物的筛选效率低,而对于去除微胶黏物有些技术比其他技术更好。自早期的研究之后,第4代筛鼓已进入市场。第4代筛鼓以具有高精确度和连贯性的楔形网筛鼓设计为主要特征。

关键词：造纸机械筛鼓技术性能表征微胶黏物去除对策

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Health 2013年第2期5卷 222-228页

作者： Felipe J.Aidar Nuno D.Garrido Antonio J.Silva Victor M.Reis daniel A.Marinho Ricardo Jaco de Oliveira 5^(th) Military State Fireman UberlândiaBrazil University of Tras-os-Montes and Alto Douro—UTAD/CIDESD Vila RealPortugal University of Beira Interior—UBI/CIDESD CovilhaPortugal University of Brasilia—UnB BrasiliaBrazil

Background: Stroke ranks third and is the leading cause of permanent disability in western countries. Furthermore there are no treatments for the psychosocial effects of this pathology. Purpose: Analyse the effect of an aquatic exercise program in depression and trace and state anxiety in subjects who suffered an ischemic stroke. Methods: Two groups were analyzed: experimental group (EG) n = 15, 50.3 ± 9.1 years;control group (CG) n = 13, 52.5 ± 7.7 years. EG underwent a 12-week aquatic exercise program. Both groups were evaluated in pre and post- treatment using Beck Depression Inventory (BDI) and Trace State Anxiety Inventory (IDATE). Wilcoxon signed-rank and Mann-Whitney tests were used to compare moments and groups, respec- tively. Results: The BDI scores of aquatic activities were: pre-treatment, 17.4 ± 7.7 and 16.9 ± 8.6 for the EG and CG, respectively;post-treat- ment, 13.2 + 7.1 and 16.4 + 7.9 for the EG and CG, respectively. The IDATE scores for anxiety trace in strength training were: pre-treatment, 43.2 + 12.5 and 42.9 + 12.2 for the EG and CG, respec- tively;post-treatment, 39.7 + 7.1 and 42.6 + 12.1 for the EG and CG, respectively. The IDATE scores for anxiety state in strength training were: pre-treatment, 46.9 + 7.6 and 47.4 + 8.1 for the EG and CG, respectively;post-treatment, 44.4 + 7.9 and 47.5 + 8.0 for the EG and CG, respectively. Significant differences were found in pre and post-treatment values in the EG and between groups in the depression and trace and state anxiety levels in post-treatment (p Conclusions: Aquatic physical activity contributes to an improvement of the levels of depression and anxiety in people who suffered a stroke.

关键词： Aquatic Physical Activity Beck Depression Inventory Cardiovascular Disease Cerebrovascular Accident Ischemic Stroke Trace State Anxiety Inventory

Two Approaches to the Study of a Controversial Relationship: Cutaneous Photosensitivity and Anti-Ro/SS-A Autoantibodies

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Open Journal of Rheumatology and Autoimmune Diseases 2014年第1期4卷 1-12页

作者： Mariela L. Paz Eliana M. Cela Alejandro Ferrari Adrián D. Friedrich Juliana Leoni daniel H. González Maglio Immunology Department Pharmacy and Biochemistry School University of Buenos Aires Buenos Aires Argentina.

Background: Autoantibodies (Aabs) are the hallmark of numerous systemic autoimmune pathologies (SAPs), for instance anti-Ro/SS-A Aabs are usually found in Systemic Lupus Erythematosus (SLE) and Sjogren’s Syndrome. Cutaneous photosensitivity (CP) is found in most forms and subsets of LE and consists of a skin rash as a result of unusual reaction to sunlight. There are many theories which relate specifically the presence of circulating anti-Ro/SS-A Aabs with the CP phenomenon, though there are several studies which are in disagreement. Results: In this study we analyzed the relationship between CP and anti-Ro Aabs by means of two approaches. The first one included an in vitro model where we evaluated by flow cytometry the binding capacity of affinity-purified Aabs to autoantigens relocalized on apoptotic keratinocyte’s surface. We found that there was no relationship between the binding capacity of serum from 10 selected patients or their corresponding purified anti-Ro52 and anti-Ro60 Aabs, and the presence or absence of CP, neither with the SAPs. The in vivo model consisted of Hairless SKH:1 mice which were induced to produce anti-murine Ro52 and/or Ro60 Aabs and were subsequently irradiated with UVB light. We evaluated the skin histology and also the epidermal production of TNF-α. We found no differences between the groups in neither of the parameters evaluated. Conclusions: These results agree with some studies on the role of the Aabs in CP, considering anti-Ro Aabs not as the only responsible for the manifestation;and disagree with many other authors, who believe in the strong association between these two events.

关键词： Cutaneous Photosensitivity Purified Anti-Ro/SS-A Autoantibodies SKH-1 Hairless Mice UVB Irradiation TNF-α

Potential of soluble CD26 as a serum marker for colorectal cancer detection

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World Journal of Clinical Oncology 2011年第6期2卷 245-261页

作者： Oscar J Cordero Monica Imbernon Loretta De Chiara Vicenta S Martinez-Zorzano daniel Ayude Maria Paez de la Cadena F Javier Rodriguez-Berrocal Department of Biochemistry and Molecular Biology University of Santiago de CompostelaSchool of BiologyCIBUUS BuildingCampus Vida15782 Santiago de CompostelaSpain Department of Biochemistry Genetics and ImmunologyUniversity of VigoSchool of BiologyAs Lagoas-Marcosende s/n36310 VigoSpain

Colorectal cancer is characterized by a low survival rate even though the basis for colon cancer development,which involves the evolution of adenomas to carcinoma,is ***,the mortality rates continue to rise in economically transitioning countries although there is the opportunity to intervene in the natural history of the adenoma–cancer sequence through risk factors,screening,and *** in particular accounted for most of the decline in colorectal cancer mortality achieved in the USA during the period *** show a better prognosis when the neoplasm is diagnosed *** the variety of screening strategies,the methods range from invasive and costly procedures such as colonoscopy to more low-cost and non-invasive tests such as the fecal occult blood test(guaiac and immunochemical).As a non-invasive biological serum marker would be of great benefit because of the performance of the test,several biomarkers,including cytologic assays,DNA and mRNA,and soluble proteins,have been *** found that the soluble CD26(sCD26)concentration is diminished in serum of colorectal cancer patients compared to healthy donors,suggesting the potential utility of a sCD26 immunochemical detection test for early ***26 originates from plasma membrane CD26 lacking its transmembrane and cytoplasmic *** 90%–95%of sCD26 has been associated with serum dipeptidyl peptidase IV(DPPIV)***-IV,assigned to the CD26 cluster,is a pleiotropic enzyme expressed mainly on epithelial cells and *** studies intended to validate this test for population screening to detect colorectal cancer and advanced adenomas are reviewed here.

关键词： Antibody arrays Bioinformatics Biomarkers cancer Clustering Cytometric beads Diagnosis Dipeptidyl peptidaseⅣ Enzyme linked immunosorbent assay Prognosis Soluble CD26 Screening Serum

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向左走,向右走——我们总会遇见

校园文苑（小学版） 2004年第19期 32-33页

作者： daniel 竹子沧桑的苦瓜 BoBC.Y. daniel BoBC.Y. 十夜的玛格丽特 Minirose

说到底,这只是一个有些老套的故事。城市里的两个陌生人,他和她,在某一天,某一地点,相遇,相识,

关键词：文科班万连水泥森林茫茫人海画中文理分科四川话理科班六班玛格丽特

Xenos peckii vision inspires an ultrathin digital camera

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Light(Science & Applications) 2018年第1期7卷 272-278页

作者： Dongmin Keum Kyung-Won Jang daniel S.Jeon Charles S.H.Hwang Elke K.Buschbeck Min H.Kim Ki-Hun Jeong Department of Bio and Brain Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Korea School of Computing Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Korea Department of Biological Sciences University of CincinnatiCincinnatiOH 45221-0006USA

Increased demand for compact devices leads to rapid development of miniaturized digital ***,conventional camera modules contain multiple lenses along the optical axis to compensate for optical aberrations that introduce technical challenges in reducing the total thickness of the camera ***,we report an ultrathin digital camera inspired by the vision principle of Xenos peckii,an endoparasite of paper *** male Xenos peckii has an unusual visual system that exhibits distinct benefits for high resolution and high sensitivity,unlike the compound eyes found in most insects and some *** biologically inspired camera features a sandwiched configuration of concave microprisms,microlenses,and pinhole arrays on a flat image *** camera shows a field-of-view(FOV)of 68 degrees with a diameter of 3.4mm and a total track length of *** biologically inspired camera offers a new opportunity for developing ultrathin cameras in medical,industrial,and military fields.

关键词： camera sandwich digital