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Using hierarchical spatial models to assess the occurrence of an island endemism: the case of Salamandra corsica

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Ecological Processes 2019年第1期8卷 199-209页

作者： daniel Escoriza Axel Hernandez GRECO Institute of Aquatic EcologyUniversity of Girona17071 GironaSpain Department of Environmental Sciences University Pasquale Paoli20250 CorteFrance.

Background:Island species are vulnerable to rapid extinction,so it is important to develop accurate methods to determine their occurrence and habitat *** this study,we assessed two methods for modeling the occurrence of the Corsican endemic Salamandra corsica,based on macro-ecological and fine habitat *** expected that models based on habitat descriptors would better estimate *** occurrence,because its distribution could be influenced by micro-environmental *** occurrence of *** was modeled according to two ensembles of variables using random ***:Salamandra corsica was mainly found in forested habitats,with a complex vertical *** habitats are associated with more stable environmental *** model based on fine habitat descriptors was better able to predict occurrence,and gave no false *** model based on macro-ecological variables underestimated the occurrence of the species on its ecological boundary,which is important as such locations may facilitate interpopulation ***:Implementing fine spatial resolution models requires greater investment of resources,but this is advisable for study of microendemic species,where it is important to reduce type II error(false negatives).

关键词： Amphibian Corsica Mediterranean islands Microhabitat Salamander

Exploiting Caenorhabditis elegans to discover human gut microbiota-mediated intervention strategies in protein conformational diseases

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Neural Regeneration Research 2022年第10期17卷 2203-2204页

作者： daniel M.Czyż Department of Microbiology and Cell Science University of FloridaGainesvilleFLUSA

Age-dependent protein-conformational diseases(PCDs),such as Alzheimer’s disease(AD),Parkinson’s disease(PD),or amyotrophic lateral sclerosis(ALS),are characterized by misfolding and aggregation of metastable proteins present within the proteome of the affected *** evidence supports the notion that bacteria and bacterial products may be affecting the stability of these culprit host proteins and therefore influence disease progression and perhaps even its *** specific culprit proteins are associated with each disease(e.g.,Aβin AD,α-synuclein in PD,and TDP-43 in ALS),bacteria found to affect these diseases do not seem to differentiate between these specific proteins but likely affect host proteostasis in general,leading to misfolding of metastable proteins encoded within the *** evidence that supports this hypothesis comes from studies where a single bacterial genus was linked to multiple *** example,a decrease in Prevotella *** linked to constipation,a condition that precedes PD motor symptoms by as much as 20 or more years(Savica et al.,2009;Zhu et al.,2014).

关键词： diseases Alzheimer folding

Buffered microclimate determines the presence of Salamandra corsica

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Journal of Forestry Research 2021年第3期32卷 1089-1093页

作者： daniel Escoriza Axel Hernandez GRECO Institute of Aquatic EcologyUniversity of Girona17071 GironaSpain Department of Environmental Sciences University Pasquale Paoli20250 CorteFrance

Numerous amphibian species occupy microhabitats with buffered thermal and moisture conditions,typically under forest ***,we assessed whether the insular endemic Salamandra corsica also uses this type of habitat,which could have important implications for its *** used data loggers to record the air temperature and air humidity at 4 h intervals over a period of 2 years,at 13 stations with a confirmed presence of *** data were compared with those recorded at Corsican weather stations and those generated by a climate model(WorldClim 2).The weather station data showed significant deviations from the probe data,by an average of-1.26℃(minimum temperature),+2.61℃(maximum temperature),and-0.04%(relative humidity).Similarly,the WorldClim 2 data showed significant deviations from the probe data,by an average of-2.49°C(minimum temperature)and+1.69℃(maximum temperature).These discrepancies refl ect the use of densely vegetated and topographically complex habitats by ***,which reduce temperature ***,our results highlight the importance of natural vegetal cover in the conservation of populations of this endemic salamander.

关键词： Fire salamander Island endemic Microclimate Probe Threatened species

Caspase-1:an important player and possible target for repair of the blood-brain barrier underlying neurodegeneration

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Neural Regeneration Research 2021年第12期16卷 2390-2392页

作者： daniel Rand Itzik Cooper The Joseph Sagol Neuroscience Center Sheba Medical CenterRamat-GanIsrael Sackler Faculty of Medicine Tel-Aviv UniversityTel AvivIsrael School of Psychology Interdisciplinary Center(IDC)HerzliyaIsrael The Nehemia Rubin Excellence in Biomedical Research-The TELEM Program Sheba Medical CenterTel-HashomerIsrael

Our ageing population is bearing an increasing burden on society with an unprecedented rise in brain disease,especially *** for neurodegeneration is practically nonexistent,one major reason being the bloodbrain barrier(BBB).The BBB is a crucial component in maintaining a healthy brain as it protects the brain from the entrance of toxins and removes them from the brain’s vicinity,providing proper clearance.

关键词： neurodegeneration barrier remove

The NLS approximation for two dimensional deep gravity waves Dedicated to Professor Jean-Yves Chemin on the Occasion of His 60th Birthday

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Science China Mathematics 2019年第6期62卷 1101-1120页

作者： Mihaela Ifrim daniel Tataru Department of Mathematics University of Wisconsin at Madison Department of Mathematics University of California at Berkeley

This article is concerned with in?nite depth gravity water waves in two space dimensions. We consider this system expressed in position-velocity potential holomorphic coordinates. Our goal is to study this problem with small wave packet data, and to show that this is well approximated by the cubic nonlinear Schr¨odinger equation(NLS) on the natural cubic time scale.

关键词： water waves gravity waves normal forms NLS approximation

Quantitative analysis of morphometry on Ribb and Gumara watersheds: Implications for soil and water conservation

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International Soil and Water Conservation Research 2019年第2期7卷 150-157页

作者： daniel Asfaw Getachew Workineh Debre Tabor University Department of Geography and Environmental Studies Ethiopia Debre Tabor University Department of Geography and Environmental Studies Ethiopia

Morphometric analysis is a quantitative measurement and mathematical analysis of *** plays a significant role in understanding the geohydrological characteristics of a drainage basin in relation to the terrain feature and its flow *** also helps to estimate the incidence of infiltration and runoff,and other related hydrological character of a watershed like erosion and sediment transport which has a strong implication for natural resource *** study has attempted to quantify the morphometric characteristics of Guna-Tana watershed for proper implementation of soil and water conservation *** (DEM) was used for extracting morphometric *** watershed covers a total area of 3601.5 km2 and it has a basin length of 78.89 *** has been tried to generate morphometric parameters which account basin drainage network,geometry,drainage texture,and relief characteristics together with hypsometric *** morphometric analysis of drainage density of the study watershed is 0.49 km/km2 which indicates the basin is highly permeable and result with better underground water storage *** number is 0.02 that implies the area is less prone to soil *** addition,it has stream frequency of 0.32 and form factor 0.57 which indicates slightly elongated basin *** analysis of its sub watersheds Gumara and Ribb was also ***,practicing soil and water conservation in the watershed could enhance/strengthen the water storage capacity,prevent sediment loss and related natural resource from the watershed that rehabilitate its productivity.

关键词： Morphometric analysis Drainage density Guna-Tana watershed Soil and water conservation

Coherent vorticity dynamics and dissipation in a utility-scale wind turbine wake with uniform inflow

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Theoretical & Applied Mechanics Letters 2021年第5期11卷 266-272页

作者： daniel Foti Department of Mechanical Engineering University of MemphisMemphisTNUSA

The vorticity dynamics and its relationship to dissipation in the wake of a utility-scale wind turbine are investigated through large-eddy *** vorticity dynamics is assessed through the enstrophy,which is related to the turbulent *** averaged enstrophy and turbulent dissipation are shown to be quantitatively similar in the *** temporal phase averaging,the vorticity fluctuations are decomposed into coherent and random fluctuations with respect to the frequency of the tip *** enstrophy in the tip vortices is dominated by coherent fluctuations,while the coherent fluctuations of root vortices are immediately saturated by the random vorticity fluctuations of the unstable hub *** coherent strain rate has significant differences com pared to the coherent enstrophy within one diameter downwind of blade tip,but the random enstrophy and strain rate are relatively *** in coherent enstrophy and strain rate decrease further from the rotor.

关键词： Wind turbine wake Coherent structures Vorticity dynamics

Pernicious anemia: What are the actual diagnosis criteria?

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World Journal of Gastroenterology 2011年第4期17卷 543-544页

作者： daniel Cattan Department of Internal Medicine and Hepato-Gastroenterology Centre Hospitalier 94195 Villeneuve Saint George France

A gastric intrinsic factor output under 200 U/h after pentagastrin stimulation (N > 2000 U/h) is specific for pernicious anemia. The other findings are either variable or non specific. Serum intrinsic factor antibodies, considered as specific in general practice, are present only in half of the patients with pernicious anemia. In their absence, since the disappearance of the Schilling tests, the gastric tubage currently used for the study of gastric acid secretion, is obligatory for the simultaneous study of intrinsic factor output. This study is important to eliminate another disease much more frequent than pernicious anemia, the protein bound to cobalamin malabsorption was observed in achlorhydric simple atrophic gastritis in the presence of intrinsic factor secretion.

关键词： Pernicious anemia Intrinsic factor Achlorhydria Schilling test Helicobacter pylori

Factors contributing to clinical picture and progression of Huntington's disease

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Neural Regeneration Research 2018年第8期13卷 1364-1365页

作者： daniel Zielonka Department of Epidemiology of Rare Disorders and Neuroepidemiology Poznan University of Medical Sciences

Huntington’s disease（HD）is an autosomal dominant,monogenic,progressive,neurodegenerative and rare disease with a frequency of10 per 100,000 in the Caucasian population and occurring more rarely in other races（Squitieri et al.,1994）.HD is,nevertheless,one of the most frequently and extensively studied diseases of those caused by a dynamic *** HD mutation is located on the short arm of the 4th chromosome within the HTT gene.

关键词： HD Factors contributing to clinical picture and progression of Huntington’s disease