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Spatio-temporal evolution of Beijing 2003 SARS epidemic

Science China Earth Sciences 2010年第7期53卷 1017-1028页

作者： CAO ZhiDong zeng dajun ZHENG XiaoLong WANG QuanYi WANG FeiYue WANG JinFeng WANG XiaoLi Key Laboratory of Complex Systems and Intelligence Science Institute of AutomationChinese Academy of SciencesBeijing 100190China Beijing Center for Disease Control and Prevention Beijing 100013China State Key Laboratory of Resources and Environmental Information System Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China

Studying spatio-temporal evolution of epidemics can uncover important aspects of interaction among people, infectious diseases, and the environment, providing useful insights and modeling support to facilitate public health response and possibly prevention measures. This paper presents an empirical spatio-temporal analysis of epidemiological data concerning 2321 SARS-infected patients in Beijing in 2003. We mapped the SARS morbidity data with the spatial data resolution at the level of street and township. Two smoothing methods, Bayesian adjustment and spatial smoothing, were applied to identify the spatial risks and spatial transmission trends. Furthermore, we explored various spatial patterns and spatio-temporal evolution of Beijing 2003 SARS epidemic using spatial statistics such as Moran’s I and LISA. Part of this study is targeted at evaluating the effectiveness of public health control measures implemented during the SARS epidemic. The main findings are as follows. (1) The diffusion speed of SARS in the northwest-southeast direction is weaker than that in northeast-southwest direction. (2) SARS’s spread risk is positively spatially associated and the strength of this spatial association has experienced changes from weak to strong and then back to weak during the lifetime of the Beijing SARS epidemic. (3) Two spatial clusters of disease cases are identified: one in the city center and the other in the eastern suburban area. These two clusters followed different evolutionary paths but interacted with each other as well. (4) Although the government missed the opportunity to contain the early outbreak of SARS in March 2003, the response strategies implemented after the mid of April were effective. These response measures not only controlled the growth of the disease cases, but also mitigated the spatial diffusion.

关键词： severe acute respiratory syndrome (SARS) Beijing morbidity rate spatial analysis spatio-temporal evolution control measures

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Forecasting complex group behavior via multiple plan recognition

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Frontiers of Computer Science 2012年第1期6卷 102-110页

作者： Xiaochen LI Wenji MAO daniel zeng State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China

Group behavior forecasting is an emergent re- search and application field in social computing. Most of the existing group behavior forecasting methods have heavily re- lied on structured data which is usually hard to obtain. To ease the heavy reliance on structured data, in this paper, we pro- pose a computational approach based on the recognition of multiple plans/intentions underlying group behavior. We fur- ther conduct human experiment to empirically evaluate the effectiveness of our proposed approach.

关键词： group behavior forecasting multiple planrecognition graph search

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Listwise approaches based on feature ranking discovery

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Frontiers of Computer Science 2012年第6期6卷 647-659页

作者： Yongqing WANG Wenji MAO daniel zeng Fen XIA Commercial Products Development Department Alibaba Inc.Hangzhou 310052China State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China Department of Management Information Systems University of ArizonaTucsonAZ 85721USA Union Research and Development Department Baidu Inc.Beijing 100085China

Listwise approaches are an important class of learning to rank, which utilizes automatic learning techniques to discover useful information. Most previous research on listwise approaches has focused on optimizing ranking models using weights and has used imprecisely labeled training data; optimizing ranking models using features was largely ignored thus the continuous performance improvement of these approaches was hindered. To address the limitations of previous listwise work, we propose a quasi-KNN model to discover the ranking of features and employ rank addition rule to calculate the weight of combination. On the basis of this, we propose three listwise algorithms, FeatureRank, BL-FeatureRank, and DiffRank. The experimental results show that our proposed algorithms can be applied to a strict ordered ranking training set and gain better performance than state-of-the-art listwise algorithms.

关键词： learning to rank listwise approach feature's ranking discovery

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Processes,feedbacks,and morphodynamic evolution of tidal flat-marsh systems:Progress and challenges

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Water Science and Engineering 2022年第2期15卷 89-102页

作者： zeng Zhou Meng-jiao Liang Lei Chen Meng-piao Xu Xue Chen Liang Geng Huan Li daniel Serrano He-yue Zhang Zheng Gong Chang-kuan Zhang State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Hohai UniversityNanjing 210098China Jiangsu Key Laboratory of Coast Ocean Resources Development and Environment Security Hohai UniversityNanjing 210098China Department of Civil Environmental and Architectural EngineeringUniversity of PaduaPadua 35122Italy

Tidal flats and saltmarshes have been a long-standing research focus because of their high socio-economic and ecological *** evolution of tidal flat-marsh systems is highly complex due to the intertwined processes operating over a variety of spatial and temporal *** a traditional research highlight,the role of regular hydrodynamic processes such as tides,waves,and river flows have been explored comprehensively with fruitful *** past decades,the changing environment(e.g.,sea level rise,increasing anthropogenic activities,and extreme weather conditions)has attracted more attention with many reported insightful *** recent advances indicate that biological activities play a critical role in tidal flat-marsh morphodynamics but are still poorly *** field of research that connects the bio-logical and physical processes is commonly described as"biogeomorphology"and requires the joint efforts by scientists from multiple dis-ciplines ranging from hydraulics,ecology,and geography to *** review aims to provide a synthesis of the current research status of tidal flat-marsh morphodynamics,with a particular emphasis on the understanding of various processes and feedbacks underlying the devel-opment of morphodynamic *** future research needs and challenges are identified to facilitate a more sustainable management strategy for tidal flats and saltmarshes under climate change.

关键词： Tidal flats Coastal wetlands Morphodynamics Saltmarshes Tidal channels Morphodynamic modeling

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Social influence and spread dynamics in social networks

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Frontiers of Computer Science 2012年第5期6卷 611-620页

作者： Xiaolong ZHENG Yongguang ZHONG daniel zeng Fei-Yue WANG State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China Department of Management Science and Engineering Qingdao UniversityQingdao 266071China

Social networks often serve as a critical medium for information dissemination, diffusion of epidemics, and spread of behavior, by shared activities or similarities be- tween individuals. Recently, we have witnessed an explosion of interest in studying social influence and spread dynamics in social networks. To date, relatively little material has been provided on a comprehensive review in this field. This brief survey addresses this issue. We present the current significant empirical studies on real social systems, including network construction methods, measures of network, and newly em- pirical results. We then provide a concise description of some related social models from both macro- and micro-level per- spectives. Due to the difficulties in combining real data and simulation data for verifying and validating real social sys- tems, we further emphasize the current research results of computational experiments. We hope this paper can provide researchers significant insights into better understanding the characteristics of personal influence and spread patterns in large-scale social systems.

关键词： social networks spread dynamics social influence computational experiment

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Apogossypolone targets mitochondria and light enhances its anticancer activity by stimulating generation of singlet oxygen and reactive oxygen species

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Chinese Journal of Cancer 2011年第1期30卷 41-53页

作者： Zhe-Yu Hu Jing Wang Gang Cheng Xiao-Feng Zhu Peng Huang dajun Yang Yi-Xin zeng State Key Laboratory of Oncology in South China Guangzhou Guangdong 510060 P. R. China Department of Experimental Research Sun Yat-sen University Cancer Center Guangzhou Guangdong 510060 P. R. China Department of Molecular Pathology The University of Texas MD Anderson Cancer Center Houston Texas 77030 USA Aseenta Therapeutics Incorporation Malvern Pennsylvania 19355 USA The First Hospital of Changsha City Changsha Hunan 410005 P. R. China.

Apogossypolone (ApoG2), a novel derivative of gossypol, has been shown to be a potent inhibitor of antiapoptotic Bcl-2 family proteins and to have antitumor activity in multiple types of cancer cells. Recent reports suggest that gossypol stimulates the generation of cellular reactive oxygen species (ROS) in leukemia and colorectal carcinoma cells; however, gossypol-mediated cell death in leukemia cells was reported to be ROS-independent. This study was conducted to clarify the effect of ApoG2-induced ROS on mitochondria and cell viability, and to further evaluate its utility as a treatment for nasopharyngeal carcinoma (NPC). We tested the photocytotoxicity of ApoG2 to the poorly differentiated NPC cell line CNE-2 using the ROS-generating TL/10 illumination system. The rapid ApoG2-induced cell death was partially reversed by the antioxidant N-acetyl-L-cysteine (NAC), but the ApoG2-induced reduction of mitochondrial membrane potential (MMP) was not reversed by NAC. In the presence of TL/10 illumination, ApoG2 generated massive amounts of singlet oxygen and was more effective in inhibiting cell growth than in the absence of illumination. We also determined the influence of light on the anti-proliferative activity of ApoG2 using a CNE-2-xenograft mouse model. ApoG2 under TL/10 illumination healed tumor wounds and suppressed tumor growth more effectively than ApoG2 treatment alone. These results indicate that the ApoG2-induced CNE-2 cell death is partly ROS-dependent. ApoG2 may be used with photodynamic therapy (PDT) to treat NPC.

关键词：线粒体膜电位活性氧物种抗癌活性单线态氧细胞死亡细胞生长鼻咽癌光动力疗法

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Entity attribute discovery and clustering from online reviews

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Frontiers of Computer Science 2014年第2期8卷 279-288页

作者： Qingliang MIAO Qiudan LI daniel zeng Yao MENG Shu ZHANG Hao YU Fujitsu Research & Development Center Beijing 100025 China Institute of Automation Chinese Academy of Sciences Beijing 100190 China Ricoh Software Research Center (Beijing) Co. Ltd. Beijing 100082 China

The rapid increase of user-generated content （UGC） is a rich source for reputation management of enti- ties, products, and services. Looking at online product re- views as a concrete example, in reviews, customers usually give opinions on multiple attributes of products, therefore the challenge is to automatically extract and cluster attributes that are mentioned. In this paper, we investigate efficient at- tribute extraction models using a semi-supervised approach. Specifically, we formulate the attribute extraction issue as a sequence labeling task and design a bootstrapped schema to train the extraction models by leveraging a small quantity of labeled reviews and a larger number of unlabeled reviews. In addition, we propose a clustering By committee （CBC） ap- proach to cluster attributes according to their semantic simi- larity. Experimental results on real world datasets show that the proposed approach is effective.

关键词： opinion mining attribute extraction attributeclustering

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The Chinese ‘‘HumanFlesh’’ Web:the first decade and beyond

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Chinese Science Bulletin 2014年第26期59卷 3352-3361页

作者： Fei-Yue Wang daniel zeng Qingpeng Zhang James A. Hendler Jianping Cao The State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Department of Management Information Systems The University of Arizona Tucson Department of Systems Engineering and Engineering Management City University of Hong Kong Tetherless World Constellation Department of Computer Science Rensselaer Polytechnic Institute Troy The Research Center for Computational Experiments and Parallel Systems National University of Defense Technology

Human flesh search(HFS), a Web-enabled crowdsourcing phenomenon, originated in China a decade ago. In this article, we present the first comprehensive empirical analysis of HFS, focusing on the scope of HFS activities, the patterns of HFS crowd collaboration process, and the characteristics of HFS participant networks. A survey of HFS participants was conducted to provide an in-depth understanding of the HFS community and various factors that motivate these participants to contribute. This article also advocates a new stream of Web science and social computing research that will be important in predicting the future growth and use of the World Wide Web.

关键词：中国人网址肉 Web功能实证分析参与者共同体万维网

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Challenges in developing polymer flocculants to improve bitumen quality in *** extraction processes:an experimental study

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Petroleum Science 2020年第3期17卷 811-821页

作者： daniel V.Dixon Stanislav R.Stoyanov Yuming Xu Hongbo zeng Joao B.P.Soares Department of Chemical and Materials Engineering University of Alberta9211-116 Street NW.EdmontonAB T6G 1H9Canada CanmetENERGY Devon.Natural Resources Canada 1 Oil Patch DriveDevonAB T9G 1A8Canada

Western Canada’s oil sands hold the third-largest hydrocarbon deposits in the ***,a very heavy petroleum,is currently recovered by surface mining with warm water or in *** processes that use organic solvents are being developed to reduce water usage and tailings *** solvent-based methods can effectively extract bitumen,removal of residual fine solids from diluted bitumen product(DBP)to meet the pipeline transport requirement of<0.5 wt%solids and water in DBP remains a major *** propose a novel area of application of polymer flocculants for fine solids removal from *** principle,polymer flocculants can be applied to help remove these residual solids in conjunction with physical separation processes to increase process effectiveness and energy *** polymers are selected and screened for flocculation behavior using kaolinite suspended in DBP and toluene,as a model *** beam reflectance measurements and force tensiometer techniques are used to determine flocculation and sedimentation in *** observed flocculation and sedimentation rate enhancements indicate that the polymers tested have only minor effects,providing opportunities for advanced polymer *** findings exemplify the challenges in identifying polymers that may be effective as flocculants in heavy petroleum media.

关键词： Non-aqueous extraction Diluted bitumen Oil-soluble polymer flocculants Sedimentation in dark and opaque media Focused beam reflectance measurements

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Real-time programmable metasurface for terahertz multifunctional wave front engineering

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Light(Science & Applications) 2023年第9期12卷 1795-1806页

作者： Feng Lan Luyang Wang Hongxin zeng Shixiong Liang Tianyang Song Wenxin Liu Pinaki Mazumder Ziqiang Yang Yaxin Zhang daniel M.Mittleman Sichuan THz Communication Technology Engineering Research Center School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313000China Zhangjiang Laboratory Shanghai 201204China National Key Laboratory of Solid-State Microwave Devices and Circuits Hebei Semiconductor Research InstituteShijiazhuang 050051China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China University of Chinese Academy of Sciences School of ElectronicElectrical and Communication EngineeringBeijing 101408China Department of Electrical Engineering and Computer Science University of MichiganAnn ArborMI 48109USA School of Engineering Brown UniversityProvidenceRI 02912USA

Terahertz(THz)technologies have become a focus of research in recent years due to their prominent role in envisioned future communication and sensing *** of the key challenges facing the field is the need for tools to enable agile engineering of THz wave ***,we describe a reconfigurable metasurface based on GaN technology with an array-of-subarrays *** subwavelength-spaced array,under the control of a 1-bit digital coding sequence,can switch between an enormous range of possible configurations,providing facile access to nearly arbitrary wave front control for signals near 0.34 *** demonstrate wide-angle beam scanning with 1°of angular precision over 70 GHz of bandwidth,as well as the generation of multi-beam and diffuse wave fronts,with a switching speed up to 100 *** device,offering the ability to rapidly reconfigure a propagating wave front for beam-forming or diffusively scattered wide-angle coverage of a scene,will open new realms of possibilities in sensing,imaging,and networking.

关键词： wave scattered arbitrary

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