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Successful occluding by absorbable sutures for epicardial collateral branch perforation

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Journal of Geriatric Cardiology 2018年第10期15卷 653-656页

作者： Li SHENG Yong-Tai GONG dang-hui sun Yue LI Department of Cardiovascular the First Affiliated Hospital of Harbin Medical UniversityHarbinChina

In order to improve the success rate of chronic total occlusion (CTO)percutaneous coronary intervention (PCI), retrograde approach has been attracted more attention.Recent study reported the collateral perforation rate was 6.9% in retrograde CTO PCI.[1,2] Collateral related perforations were higher in patients with the epicardial collateral than that with the septal collateral.[3]Several techniques have been developed to deal with the collateral branch perforation.Here,we described the treatment of epicardial collateral branch perforation by absorbable suture segments embolization through microcatheter during retrograde CTO PCI.

关键词： Epicardial collateral branch perforation Occluding by absorbable sutures Percutaneous coronary intervention

A novel treatment of refractory coronary embolism:thrombus aspiration catheter-assisted twisting wire technique

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Journal of Geriatric Cardiology 2020年第2期17卷 110-115页

作者： Yi-Lun ZOU Jian-Qiang LI Yong-Tai GONG dang-hui sun Yue LI Department of Cardiology the First Affiliated Hospital of Harbin Medical University

Coronary embolism caused by the thrombus from guiding catheters is a rare and challenging complication,which may result in serious and fatal consequences due to the loss of blood flow of the coronary artery during percutaneous coronary intervention(PCI).Current strategies for the reduction of thrombus burden include pharmacological agents(typically glycoprotein IIb/IIIa platelet inhibitors),embolic protection devices(filters and distal balloon occlusion with aspiration),mechanical thrombectomy and manual or aspiration thrombectomy devices.[1]The above strategies are widely used as the first-line treatments,but have limitations for some refractory thrombus.A few techniques have been invented before to address this issue,[2–6]but they are not always effective or unavailable in some medical centers.

关键词： Complication Percutaneous coronary intervention Refractory thrombus embolism Thrombectomy

Intravascular ultrasound-guided “extended” reverse controlled antegrade and retrograde subintimal tracking technique using a cutting balloon for recanalizing chronic coronary total occlusion with a side branch

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Journal of Geriatric Cardiology 2019年第6期16卷 498-501页

作者： Yong-Tai GONG Jian-Qiang LI Li SHENG dang-hui sun Yue LI Department of Cardiology the First Affiliated Hospital of Harbin Medical University

Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) represents the most technically challenging procedure in contemporary interventional cardiology.[1] Blunt lesions and presence of proximal side branch are considered to be strong predictors of reduced technical success.[ 2,3] For such lesions, the antegrade approach may not be feasible or desirable, and the retrograde approach can be used as the initial crossing strategy. However, when treating the blunt CTO with a large side branch proximal to the occlusion, the side branch might be occluded after stent implantation if the retrograde guidewire passed the occluded segment through the subintimal space and re-entered into the true lumen at the opposite side of the side branch.[4] We reported a useful method to solve the above issue which utilizes intravascular ultrasound (IVUS) to guide “extended” reverse controlled antegrade and retrograde subintimal tracking (CART) technique with a cutting balloon.

关键词： Chronic total occlusion Cutting balloon Intravascular ultrasound Percutaneous coronary intervention Reverse controlled antegrade and retrograde tracking technique

The balloon occlusion and thrombus aspiration catheter mediated-distal coronary perfusion technique(BI-RESCUE)for treatment of coronary artery perforation

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Journal of Geriatric Cardiology 2021年第2期18卷 150-154页

作者： Yong-Tai GONG Song ZHANG Ding-Yu WANG dang-hui sun Li SHENG Yue LI Cardiovascular Department the First Affiliated Hospital of Harbin Medical UniversityHarbinChina

Coronary artery perforation(CAP)remains an infrequent but potentially lifethreatening complication during percutaneous coronary intervention(PCI).Although the prevalence of CAP is about 0.2%−0.9%in relatively low risk PCI,the incidence could up to 9%in complex clinical scenarios such as severe coronary calcification,chronic total occlusions and rotational atherectomy.[1]Despite the new techniques and equipment had lower morbidity and mortality,up to 17%of acute CAP cases would evolve to tamponade and subsequent death.

关键词： coronary occlusion balloon

Removal of refractory thrombus by 5F child catheter in patients with subacute myocardial infarction

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Journal of Geriatric Cardiology 2019年第2期16卷 168-172页

作者： Li SHENG Jian-Qiang LI dang-hui sun Yong-Tai GONG Jing-Yi XUE Yue LI Department of Cardiology the First Affiliated Hospital of Harbin Medical University

No-reflow phenomenon is common in patients with acute coronary syndrome(ACS)after percutaneous coronary intervention(PCI),and it is strongly associated with adverse clinical prognosis.Previous studies have shown that heavy thrombus burden could predict the development of no-reflow in PCI.Manual and mechanical thrombus aspiration catheters are widely used;however,there is still residual refractory thrombus left after the routine use of thrombectomy,especially in patients with subacute myocardial infarction(SMI).In our practice,child catheter aspiration has been used as a safe and effective approach to solve the residual thrombus in SMI patients.We described this technique in detail by a series of cases.

关键词： Percutaneous coronary intervention Refractory thrombus Subacute myocardial infarction Thrombus aspiration

Presence of Severe Stenosis in Most Culprit Lesions of Patients with ST-segment Elevation Myocardial Infarction

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Chinese Medical Journal 2016年第17期129卷 2074-2078页

作者： Li Sheng Shuang Li Jian-Qiang Li Jing-Yi Xue Yan-Ming sun Yong-Tai Gong Ling Jing dang-hui sun Wei-Min Li Ding-Yu Wang Yue Li Department of Cardiology The First Affiliated Hospital of Harbin Medical University Harbin Medical University Harbin Heilongjiang 150001 China Postgraduate Institute Harbin Medical University Harbin Heilongjiang 150081 China

Background： Previous studies revealed that culprit vessels of ST-segment elevation myocardial infarction （STEMI） were often related to mild or moderate stenosis. However, recent studies suggested that severe stenosis was primarily found in culprit lesions. The objective of this study was to analyze the stenosis severity of culprit lesions in STEMI patients and to clarity the paradoxical results. Methods： A total of 489 consecutive STEMI patients who underwent primary percutaneous coronary intervention were retrospectively studied from January 2012 to December 2014. The patients were divided into three groups based on stenosis severity using quantitative coronary analysis： Group A, 314 cases, stenosis 〉70%： Group B, 127 cases, stenosis 50-70%： and Group C, 48 cases, stenosis 〈_50%,. The clinical, demographic, and angiographic data of all groups were analyzed. Results： Patients in Group A exhibited a significantly higher prevalence of history of angina pectoris （95.9% vs. 62.5%, P 〈 0.001 ）, inultivessel disease （73.2% vs. 54.2%, P = 0.007）, and lower cardiac ejection ITaction （53.3 ± 8.6 vs. 56.8 ± 8.4, P = 0.009） than those in Group C. Multivariable analysis revealed that history of angina pectoris （odds ratio [OR]： 13.89, 95% confidence interval [（7]： 6.21-31.11 ） and multivessel disease （OR： 2.32, 95%, CI： 1.25-4.31 ） were correlated with severe stenosis of the culprit lesion in Group A. Conclusions： Most culprit lesions in STEM[ patients were severe stenosis. These patients exhibited a higher prevalence of angina history and multivessel diseases.

关键词： Percutaneous Coronary Intervention Quantitative Coronary Angiography ST-segment Elevation Myocardial Infarction

Effect of perindopril on the myocardial energy consumption in patients with heart failure after myocardial infarction

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Journal of Hainan Medical University 2017年第13期23卷 22-25页

作者： Da-Peng Li dang-hui sun Lin Wei Xi-Ying Yu Shi-Jin Na The First Hospital of Harbin City Heilongjiang150010 The First Hospital Affiliated to Harbin Medical University 150011

Objective:To explore the clinical efficacy of perinodopril in the treatment of heart failure in patients after myocardial infarction and effect on the myocardial energy consumption. Methods:A total of 87 patients with heart failure after myocardial infarction who were admitted in our hospital from August, 2014 to October, 2015 were included in the study and divided into the routine dose group (n=43, perinodopril 4 mg/d) and high dose group (n=44, perinodopril 8 mg/d) according to the long-term oral dose. All the patients were given perinodopril, continuously for 6 months. The changes of blood pressure and serum biochemical indicators before and after treatment in the two groups were compared. The changes of cardiac function indicators and myocardial energy consumption indicators before and after treatment in the two groups were compared. 6MWT 6 months and 1 year after treatment in the two groups was calculated.Results: The plasma BNP and H-FABP levels, LVEDD, LVESD, MEE, and cESS after treatment in the two groups were significantly reduced when compared with before treatment, and those in the high dose group were significantly lower than those in the low dose group. LVEF and FS after treatment in the two groups were significantly increased, and those in the high dose group were significantly greater than those in the routine dose group. The seurm potassium level after treatment in the high dose group was significantly elevated when compared with before treatment, but was not significantly different from that in the routine dose group. SBP, DBP, and Scr levels after treatment in the two groups were not significantly changed. 6MWT 6 months and 1 year after treatment in the high dose group was significantly greater than that in the routine dose group.Conclusions: Perinodopril in a high dose can significantly reduce the plasma BNP and H-FABP levels in patients with heart failure after myocardial infarction, inhibit the ventricular remodeling, promote the recovery of systolic function, reduce the myocardial energy con

关键词： Myocardial infarction Heart failure Perinodopril Cardiac function Myocardial energy consumption

QAR Data Imputation Using Generative Adversarial Network with Self-Attention Mechanism

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Big Data Mining and Analytics 2024年第1期7卷 12-28页

作者： Jingqi Zhao Chuitian Rong Xin dang Huabo sun School of Computer Science and Technology Tiangong UniversityTianjin 300387China Institute of Aviation Safety China Academy of Civil Aviation Science and TechnologyBeijing 100028China

Quick Access Recorder(QAR),an important device for storing data from various flight parameters,contains a large amount of valuable data and comprehensively records the real state of the airline flight.However,the recorded data have certain missing values due to factors,such as weather and equipment anomalies.These missing values seriously affect the analysis of QAR data by aeronautical engineers,such as airline flight scenario reproduction and airline flight safety status assessment.Therefore,imputing missing values in the QAR data,which can further guarantee the flight safety of airlines,is crucial.QAR data also have multivariate,multiprocess,and temporal features.Therefore,we innovatively propose the imputation models A-AEGAN("A"denotes attention mechanism,"AE"denotes autoencoder,and"GAN"denotes generative adversarial network)and SA-AEGAN("SA"denotes self-attentive mechanism)for missing values of QAR data,which can be effectively applied to QAR data.Specifically,we apply an innovative generative adversarial network to impute missing values from QAR data.The improved gated recurrent unit is then introduced as the neural unit of GAN,which can successfully capture the temporal relationships in QAR data.In addition,we modify the basic structure of GAN by using an autoencoder as the generator and a recurrent neural network as the discriminator.The missing values in the QAR data are imputed by using the adversarial relationship between generator and discriminator.We introduce an attention mechanism in the autoencoder to further improve the capability of the proposed model to capture the features of QAR data.Attention mechanisms can maintain the correlation among QAR data and improve the capability of the model to impute missing data.Furthermore,we improve the proposed model by integrating a self-attention mechanism to further capture the relationship between different parameters within the QAR data.Experimental results on real datasets demonstrate that the model can reasonably impute the missing values in QAR data wi

关键词： multivariate time series data imputation self-attention Generative Adversarial Network(GAN)

Influence of varied drought types on soil conservation service within the framework of climate change:insights from the Jinghe River Basin,China

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Journal of Arid Land 2024年第2期16卷 220-245页

作者： BAI Jizhou LI Jing RAN hui ZHOU Zixiang dang hui ZHANG Cheng YU Yuyang School of Geography and Tourism Shaanxi Normal UniversityXi'an 710119China College of Geomatics Xi'an University of Science and TechnologyXi'an 710054China

Severe soil erosion and drought are the two main factors affecting the ecological security of the Loess Plateau,China.Investigating the influence of drought on soil conservation service is of great importance to regional environmental protection and sustainable development.However,there is little research on the coupling relationship between them.In this study,focusing on the Jinghe River Basin,China as a case study,we conducted a quantitative evaluation on meteorological,hydrological,and agricultural droughts(represented by the Standardized Precipitation Index(SPI),Standardized Runoff Index(SRI),and Standardized Soil Moisture Index(SSMI),respectively)using the Variable Infiltration Capacity(VIC)model,and quantified the soil conservation service using the Revised Universal Soil Loss Equation(RUSLE)in the historical period(2000-2019)and future period(2026-2060)under two Representative Concentration Pathways(RCPs)(RCP4.5 and RCP8.5).We further examined the influence of the three types of drought on soil conservation service at annual and seasonal scales.The NASA Earth Exchange Global Daily Downscaled Projections(NEX-GDDP)dataset was used to predict and model the hydrometeorological elements in the future period under the RCP4.5 and RCP8.5 scenarios.The results showed that in the historical period,annual-scale meteorological drought exhibited the highest intensity,while seasonal-scale drought was generally weakest in autumn and most severe in summer.Drought intensity of all three types of drought will increase over the next 40 years,with a greater increase under the RCP4.5 scenario than under the RCP8.5 scenario.Furthermore,the intra-annual variation in the drought intensity of the three types of drought becomes smaller under the two future scenarios relative to the historical period(2000-2019).Soil conservation service exhibits a distribution pattern characterized by high levels in the southwest and southeast and lower levels in the north,and this pattern has remained consistent both in the historical and future pe

关键词： meteorological drought hydrological drought agricultural drought soil conservation service Variable Infiltration Capacity(VIC)model Revised Universal Soil Loss Equation(RUSLE) Jinghe River Basin