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核幔边界条件下MgSiO_3熔体的密度

矿物岩石地球化学通报 2016年第1期35卷 27-27页

作者： Petitgirard S Malfait W J Sinmyo R Kupenko I Hennet L Harris D dane t Burghammer M Rubie D C 夏群科

地球深部物质的密度差异影响着地球结构的分层特征以及物质的迁移方式,是理解深部地球动力学行为的关键因素。对于地幔来说,硅酸盐熔体和矿物之间的密度差异决定了熔体的居留位置。但是下地幔压力条件下熔体密度的测定一直是个技术难题... 详细信息

地球深部物质的密度差异影响着地球结构的分层特征以及物质的迁移方式,是理解深部地球动力学行为的关键因素。对于地幔来说,硅酸盐熔体和矿物之间的密度差异决定了熔体的居留位置。但是下地幔压力条件下熔体密度的测定一直是个技术难题。德国Bayreuth大学的Sylvain Petitgirard与合作者发展了一个新技术,将X射线吸收方法成功用于金刚石压腔,

关键词：核幔边界 MgSiO_3 金刚石压腔迁移方式地球深部下地幔地球结构地球动力学压力条件误差范围

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Machine learning predictions of irradiation embrittlement in reactor pressure vessel steels

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npj Computational Materials 2022年第1期8卷 795-805页

作者： Yu-chen Liu Henry Wu tam Mayeshiba Benjamin Afflerbach Ryan Jacobs Josh Perry Jerit George Josh Cordell Jinyu Xia Hao Yuan Aren Lorenson Haotian Wu Matthew Parker Fenil Doshi Alexander Politowicz Linda Xiao dane Morgan Peter Wells Nathan Almirall takuya Yamamoto G.Robert Odette Materials Science and Engineering Department University of Wisconsin-MadisonMadisonWI53706USA Hierarchical Green-Energy Materials(Hi-GEM)Research Center National Cheng Kung UniversityTainan70101TaiwanCHINA Materials Science and Engineering Department National Cheng Kung UniversityTainan70101TaiwanCHINA Mechanical Engineering Department University of CaliforniaSanta BarbaraCA93106USA

Irradiation increases the yield stress and embrittles light water reactor(LWR)pressure vessel *** this study,we demonstrate some of the potential benefits and risks of using machine learning models to predict irradiation hardening extrapolated to low flux,high fluence,extended life *** machine learning training data included the Irradiation Variable for lower flux irradiations up to an intermediate fluence,plus the Belgian Reactor 2 and Advanced test Reactor 1 for very high flux irradiations,up to very high ***,the machine learning model predictions for the high fluence,intermediate flux Advanced test Reactor 2 irradiations are superior to extrapolations of existing hardening *** successful extrapolations showed that machine learning models are capable of capturing key intermediate flux effects at high *** approaches,applied to expanded databases,could be used to predict hardening in LWRs under life-extension conditions.

关键词： life irradiation expanded

先进密封管中子发生器的可移动中子照相系统及其性能

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国外科技资料 1996年第3期 50-53页

作者： dane,WE 黄华国

德国Ｏｔｔｏｂｒｕｍ公司的ＩＡＢＧ实验室正在研制首台ＤＩＡＮＥ中子照相系统。该系统利用法国ＳＯＤＥＲＮ公司为此项工作研制的，定名为ＧＥＮＩＥ４６的新型Ｄ－Ｔ中子发生器，现正把这种发生器装入先进的ＬＴＶ公司生产的可移动... 详细信息

德国Ｏｔｔｏｂｒｕｍ公司的ＩＡＢＧ实验室正在研制首台ＤＩＡＮＥ中子照相系统。该系统利用法国ＳＯＤＥＲＮ公司为此项工作研制的，定名为ＧＥＮＩＥ４６的新型Ｄ－Ｔ中子发生器，现正把这种发生器装入先进的ＬＴＶ公司生产的可移动中子照相系统。该系统用于对组件和结构件作可行的无反应堆检测。现在ＧＥ－ＮＩＥ４６管的最高中子输出是５×１０＾１１中子／秒（１４ＭｅＶ），加速电压２２５ｋＶ，离子束电流小于１０ｍＡ。

关键词：照相装置密封管中子发生器中子照相系统

Anatomical and Radiological Description of the Macaca fascicularis Spine in Comparison with the Human Spine

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Open Journal of Veterinary Medicine 2022年第12期12卷 171-186页

作者： Anant Krishnan Guneet Kaleka Scott Emerson Guy Sovak Heather Simmons Kevin Brunner dane Schalk John Sledge Amber Hoggatt Shanker Nesathurai Department of Diagnostic Radiology Oakland University William Beaumont School of Medicine Auburn Hills USA Department of Diagnostic Radiology and Molecular Imaging Beaumont Hospital Royal Oak USA Canadian Memorial Chiropractic College Toronto Canada Wisconsin National Primate Research Center Madison USA Lafayette Bone and Joint Clinic Lafayette USA Harvard Medical School Boston USA Department of Physical Medicine and Rehabilitation Hamilton Health Sciences Corporation Hamilton Canada Division of Physical Medicine and Rehabilitation Michael G. DeGroote School of Medicine McMaster University Hamilton Canada

Background: this paper describes and displays the spinal radiological anatomy and associated pathology in a Macaca fascicularis and compares it to the spinal anatomy of humans. Animal models are commonly used in research. As compared to Macaca mulatta, the anatomy of M. fascicularis is less well described in the literature. Materials and methods: the authors anatomically reconstructed and reviewed the defleshed spine of a single adult M. fascicularis visually, radiographically, and with high resolution Ct. Results: 7 cervical, 12 thoracic, 6 lumbar, 3 sacral, and 16 caudal vertebrae were identified. Similarities in the spine to humans were seen as well as differences such as the beaked anterior arch of C1, the anterior pointed lower lumbar vertebrae, the upward curved transverse processes, and presence of three sacral segments. Degenerative changes were seen at multiple locations similar to humans though most pronounced at t3-4. Conclusions: this paper addresses the normal spinal anatomy and degenerative changes in an adult M. fascicularis and compares it to humans.

关键词： Macaca Fascicularis Macaques Spine Anatomy Radiology Ct Comparative Study Computed tomography

Attosecond Delays of High-Harmonic Emissions from Hydrogen Isotopes Measured by XUV Interferometer

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Ultrafast Science 2022年第5期2卷 21-26页

作者： Mumta Hena Mustary Liang Xu Wanyang Wu Nida Haram dane E.laban Han Xu Feng He R.t.Sang Igor V.Litvinyuk Centre for Quantum Dynamics Griffith UniversityBrisbaneQueensland 4111Australia Key Laboratory for Laser Plasmas(Ministry of Education)and School of Physics and Astronomy Collaborative Innovation Center for IFSA(CICIFSA)Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Key Lab of Modern Optical System University of Shanghai for Science and Technology200093 ShanghaiChina CAS Center for Excellence in Ultra-Intense Laser Science Shanghai 201800China

High-harmonic spectroscopy can access structural and dynamical information on molecular systems encoded in the amplitude and phase of high-harmonic generation(HHG)***,measurement of the harmonic phase is a daunting ***,we present a precise measurement of HHG phase difference between two isotopes of molecular hydrogen using the advanced extreme-ultraviolet(XUV)Gouy phase *** measured phase difference is about 200 mrad,corresponding to~3 attoseconds(1 as=10−18 s)time delay which is nearly independent of harmonic *** measurements agree very well with numerical calculations of a four-dimensional time-dependent Schödinger *** simulations also reveal the effects of molecular orientation and intramolecular two-center interference on the measured phase *** technique opens a new avenue for measuring the phase of harmonic emission for different atoms and *** with isomeric or isotopic comparisons,it also enables the observation of subtle effects of molecular structures and nuclear motion on electron dynamics in strong laser fields.

关键词： equation harmonic precise

双能Ct小肠成像碘密度评价克罗恩病活动性炎症:与组织病理学分析的比较

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国际医学放射学杂志 2021年第6期 736-736页

作者： B.dane S.Sarkar M.Nazarian H.Galitzer t.O'Donnell F.Remzi 万怡轩

研究证明与临床标志物炎症相比,双能Ct小肠成像(DECtE)可用于描述克罗恩病的活动情况,但尚未有研究与组织病理学标本进行比较。目的比较同一克罗恩病病人

关键词：

健骨方对破骨细胞形成和成骨细胞增殖分化的影响

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中国骨质疏松杂志 2022年第12期28卷 1728-1734页

作者：许华珍黄丹娥郑柳怡姚楠蔡大可甘海宁黄雪君胡子旋赵自明陈玉兴广州中医药大学第五临床医学院广东广州510405 广东省第二中医院(广东省中医药工程技术研究院) 广东广州510095 广东省中医药研究开发重点实验室广东广州510095

目的探讨健骨方水提物对破骨细胞分化及成骨细胞增殖分化的影响。方法制备健骨方水提物,通过Mtt法测定药物对骨髓单核巨噬细胞(BMMs)细胞的毒性,采用核因子κB受体活化因子配体(RANKL)诱导BMMs分化形成破骨细胞,加入不同浓度药物进行干... 详细信息

目的探讨健骨方水提物对破骨细胞分化及成骨细胞增殖分化的影响。方法制备健骨方水提物,通过Mtt法测定药物对骨髓单核巨噬细胞(BMMs)细胞的毒性,采用核因子κB受体活化因子配体(RANKL)诱导BMMs分化形成破骨细胞,加入不同浓度药物进行干预,采用抗酒石酸酸性磷酸酶(tRACP)染色法测定破骨细胞分化抑制作用,采用Western Blot法测定RANKL诱导的NF-κB破骨细胞分化信号通路,运用Rt-qPCR法测定信号通路下游破骨细胞分化关键基因NFAtc1、C-FOS等的mRNA表达水平。以MC3t3-E1细胞作为前体成骨细胞,加入不同浓度药物进行干预,通过CCK8法测定细胞增殖能力、PNPP法检测碱性磷酸酶(ALP)活性、茜素红S染色法测定细胞矿化能力。结果Mtt法结果显示,健骨方细胞有毒性浓度大于500μg/mL(Ptc1等的mRNA表达水平(Pt3-E1细胞增殖、提高ALP活性及增加成骨细胞钙化的能力。结论健骨方具有抑制破骨细胞分化和促进成骨前体细胞增殖、分化、矿化的药效作用。其作用与抑制破骨细胞分化RANKL-NF-κB信号通路及其下游C-FOS、NFAtc1等基因,上调成骨细胞分化促进因子CAL1A2、SPARC和FOSL1基因的表达有关。

关键词：健骨方破骨细胞成骨细胞骨质疏松症中医药

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triton WR-1339致小鼠高脂血症模型的脂代谢与炎症变化探讨

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广东药科大学学报 2019年第6期35卷 793-797页

作者：李钰婷蔡大可占心佾郑柳怡杨九妹黄雪君黄丹娥陈玉兴甘海宁广州中医药大学第五临床医学院广东广州510405 广东省中医药工程技术研究院广东广州510095 广东省中医药研究开发重点实验室广东广州510095

目的通过考察注射triton WR-1339对小鼠血脂及炎症指标的影响,摸索脂代谢紊乱与炎症的关系。方法将C57BL/6随机分成6组,分别为正常组、4 h组、8 h组、36 h组、2t组,3t组。4 h、8 h、36 h组分别采用triton WR-1339(300 mg/kg)单次肌肉注... 详细信息

目的通过考察注射triton WR-1339对小鼠血脂及炎症指标的影响,摸索脂代谢紊乱与炎症的关系。方法将C57BL/6随机分成6组,分别为正常组、4 h组、8 h组、36 h组、2t组,3t组。4 h、8 h、36 h组分别采用triton WR-1339(300 mg/kg)单次肌肉注射,在相应时间点取血清及肝脏;2t组为间隔36 h进行第2次肌肉注射triton WR-1339,末次注射36 h后取材;3t组为间隔36 h进行第3次肌肉注射triton WR-1339,36 h后取材;测定各组中血清中总胆固醇(tC)、总三酯甘油(tG)、IL-1β、IL-6、MCP-1含量;肝脏进行HE染色,免疫组化检测肝脏中CD68、IL-1β蛋白的表达水平。结果与正常组比较,单次给予triton WR-1339造模剂后4 h和8 h血清tC、tG无显著变化,36 h后以及2、3次重复造模后显著升高(Ptriton WR-1339所致肝脏炎症反应先于高脂血症的发生,且与MCP-1及M1巨噬细胞形成有密切关系。

关键词： triton WR-1339 高脂血症炎症 MCP-1 巨噬细胞

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