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The function of central 5-HT-hypothalamus OT-colonic OT receptor axis

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The function of central 5-HT-hypothalamus OT-colonic OT rece...

Synthesis and structure a luminescent copper（Ⅰ） thiophene-pyrazole complex

中国生理学会消化与营养专业委员会成立大会暨第一届学术会议

作者： Tao-Fang Xi dan-ni li 谢冬萍 Tongji University School of Medicine 同济大学医学院

Objective Our previous studies showed that oxytocin(OT)is involved in colonic *** density of serotonergic fibers in the hypothalamus is found mostly in regions where oxytocinergic cells *** this study central 5-HT-dcficient mice were used to investigate the effect of OT on colonic motility and the mechanisms ***:The colonic transits were measured in *** contractions of longitudinal muscle strips of colon were detected by using organ bath in *** receptor was detected by *** concentrations in hypothalamus pituitary and serum were tested by ***:The transmit time of wild type mice but not central 5-HT-deficient mice decreased with the *** increased the colonic contraction both in central 5-HT-deficient and wild type *** increase in central 5-HT-deficient was weaker than that of in wild type *** OT receptor antagonist atosiban blocked the OT-induccd colonic contraction in central 5-HT-deficicnt *** blocked the OT-induced colonic contraction in central 5-HT-deficient *** receptor expressed in myenteric plexus of *** plasma concentration of OT decreased in central 5-HT-deficient *** concentration of OT in hypothalamus but not in pituitary decreased in 5-HT-deficient ***:Central 5-HT affects the synthesis of OT in *** then affects the colonic motility by changing the response of colonic OT receptor in myenteric plexus on OT.

关键词： 5-HT Oxytocin Oxytocin receptor Colon Smooth muscle contraction

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Synthesis and structure a luminescent copper（Ⅰ） thiophene...

Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

第六届全国物理无机化学会议

作者： liu-Jun Guo,Wen-Xiu ni,dan li~* Department of Chemistry,Shantou University,Guangdong 515063

＜正＞More and more coordination compounds based on Cu（I）-pyrazolates were investigated for their interesting photoluminescence properties and potential applications in photofunctional materials and chemical sensors. Dependent on the steric crowd,coordination compounds based on Cu（I）-pyrazolated have extensively reported

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong li li dan Jing Peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 *** results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the *** higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in *** flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through *** occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.

关键词： Carbon variability ENSO modulation CMIP6 models

不同结构导流体对混流式核主泵水力性能的影响

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哈尔滨工程大学学报 2016年第9期37卷 1250-1255页

作者：杨敏官周志伟高波倪丹李玉婷江苏大学能源与动力工程学院江苏镇江212013

为研究混流式核主泵内部流动情况,提高核主泵的水力效率,对不同结构导流体的混流式核主泵水力模型的三维湍流流场进行了数值模拟,研究导流体结构对混流式核主泵模型水力性能的影响。结果表明:对于只加导流环、导叶叶片对称布置的导流体... 详细信息

为研究混流式核主泵内部流动情况,提高核主泵的水力效率,对不同结构导流体的混流式核主泵水力模型的三维湍流流场进行了数值模拟,研究导流体结构对混流式核主泵模型水力性能的影响。结果表明:对于只加导流环、导叶叶片对称布置的导流体模型泵,当导流环方案为L=15 mm、θ=15°时,模型泵水力效率值最高;对于不加导流环、导叶叶片非对称布置的导流体模型泵,当γ1取24°时,模型泵水力效率值最高;对于加导流环、导叶叶片非对称布置的导流体模型泵,当导流环方案:L=15 mm、θ=15°、导叶叶片布置方案γ1=24°时,模型泵水力效率值最高。研究结果揭示了不同结构导流体对核主泵模型泵内部流场的影响规律,为高效水力模型优化设计提供参考。

关键词：核主泵混流叶轮导流体内部流动水力性能

混流式核主泵叶轮叶片厚度分布规律对能量性能的影响

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流体机械 2016年第9期44卷 25-30页

作者：杨敏官李玉婷倪丹李长军江苏大学江苏镇江212013 中核集团中国中原对外工程有限公司上海200233

采用数值计算方法,开展混流式核主泵叶轮叶片自前盖板至后盖板方向厚度分布规律对能量性能影响的研究。通过对5种具有不同厚度分布规律叶片的叶轮进行比较分析,探索最佳叶片厚度比值和其对叶片表面静压力分布规律的影响。结果表明:当叶... 详细信息

采用数值计算方法,开展混流式核主泵叶轮叶片自前盖板至后盖板方向厚度分布规律对能量性能影响的研究。通过对5种具有不同厚度分布规律叶片的叶轮进行比较分析,探索最佳叶片厚度比值和其对叶片表面静压力分布规律的影响。结果表明:当叶片后盖板处厚度与前盖板处厚度比值L=1.5时,叶轮的水力效率达到最高,当L=1.25时叶片做功能力低,叶轮内能量损失大,水力效率较低;在小流量工况下,随着比值L的增加,相同流量下扬程和水力效率都随之升高;在大流量工况下,扬程和水力效率都随着L的增大而降低;叶轮流道内压能沿着前盖板至后盖板方向增大并且最大压能位置向中间移动。

关键词：核主泵混流式叶轮叶片厚度叶片表面静压能量性能

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin li Jian Xiang Lu Qiu Xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong liu dan Xiao Zhaoyu Jin Panpan li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

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抗阿片成瘾药物研究历史与现状

中国药理学与毒理学杂志 2012年第3期26卷 255-262页

作者：李锦曹丹旎吴宁李斐宋睿苏瑞斌军事医学科学院毒物药物研究所

阿片成瘾是一种慢性复发性脑疾病,临床症状包括躯体依赖、稽延症状、精神依赖和复吸,治疗的关键是防复吸。防复吸药物的研究包括以阿片受体和非阿片受体为靶标的药物。代表性药物分别为阿片受体激动剂美沙酮和受体阻断剂纳屈酮,新型阿... 详细信息

阿片成瘾是一种慢性复发性脑疾病,临床症状包括躯体依赖、稽延症状、精神依赖和复吸,治疗的关键是防复吸。防复吸药物的研究包括以阿片受体和非阿片受体为靶标的药物。代表性药物分别为阿片受体激动剂美沙酮和受体阻断剂纳屈酮,新型阿片受体配体噻吩诺啡能够完全阻断吗啡等阿片类药物引起的躯体和精神依赖,防止阿片复吸。研究表明,参与调节阿片精神依赖和复吸的非阿片受体作用系统包括多巴胺受体、兴奋性氨基酸受体、γ-氨基丁酸受体、乙酰胆碱受体、5-HT受体、CB1受体和神经营养因子受体等。多巴胺D3受体阻断剂Y-QA14自身无致成瘾性,同时具有抗可卡因和海洛因成瘾及防复吸的作用。咪唑啉Ⅰ型受体激动剂胍丁胺具有抗阿片躯体和精神依赖、缓解稽延症状和防复吸的作用,机制与激活咪唑啉Ⅰ型受体后减轻阿片受体、多巴胺系统和谷氨酸系统的代偿性适应用关。本文将就阿片、阿片成瘾生物学基础、防阿片复吸药物研发展、作用机制、历史、现状和发展趋势加以综述。

关键词：阿片成瘾复吸防复吸药多巴胺胍丁胺

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基于遗传算法的七自由度机器人轨迹规划

实验室研究与探索 2016年第9期35卷 33-37页

作者：马丹妮李传江张自强广东省电信规划设计院有限公司广东广州528000 上海师范大学信息机电学院上海201418

针对七自由度串联机器人Robai Cyton Gamma 300轨迹规划问题,采用改进遗传算法规划机器人各关节的运动轨迹。利用D-H表示法建立起机器人末端执行器的位姿与参考坐标系之间的齐次变换矩阵,采用遗传算法优化BP神经网络求解机器人的运动学... 详细信息

针对七自由度串联机器人Robai Cyton Gamma 300轨迹规划问题,采用改进遗传算法规划机器人各关节的运动轨迹。利用D-H表示法建立起机器人末端执行器的位姿与参考坐标系之间的齐次变换矩阵,采用遗传算法优化BP神经网络求解机器人的运动学求逆解。利用5次B样条曲线在关节空间构造机器人各关节随时间变化的运动轨迹。在满足运动学约束条件下,对传统遗传算法在编码方式、遗传算子、交叉概率和变异概率等方面进行改进,对机器人各关节运动轨迹进行时间最优规划。运用Matlab对研究进行了仿真实验。结果表明,经改进遗传算法优化后的机器人运动轨迹时间明显缩短,各关节的角速度、加速度和加加速度曲线连续无突变,从而验证了该方法的有效性。

关键词：遗传算法 Robai Cyton Gamma 300机器人 Bezier曲线轨迹优化

呼吸训练对经鼻垂体瘤切除术患者术后呼吸舒适度及焦虑的影响

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中国现代医学杂志 2015年第12期25卷 110-112页

作者：周丹李丹妮周阿南张翠翠沙晶刘东颖李杰哈尔滨医科大学附属肿瘤医院神经外科黑龙江哈尔滨150040

目的探讨术前呼吸训练对经鼻垂体瘤切除术患者术后呼吸舒适度及焦虑的影响。方法将100例垂体瘤患者随机分为试验组及对照组,每组50例,试验组术前经口呼吸训练,对照组术前未经口呼吸训练。对两组患者的呼吸不适及术后焦虑情况进行评定。... 详细信息

目的探讨术前呼吸训练对经鼻垂体瘤切除术患者术后呼吸舒适度及焦虑的影响。方法将100例垂体瘤患者随机分为试验组及对照组,每组50例,试验组术前经口呼吸训练,对照组术前未经口呼吸训练。对两组患者的呼吸不适及术后焦虑情况进行评定。结果呼吸训练后两组患者的呼吸不适及焦虑对比差异有统计学意义(P<0.01)。结论术前对经鼻垂体瘤切除术患者行经口呼吸训练能明显改善患者术后呼吸不适及焦虑情绪。

关键词：垂体瘤呼吸训练呼吸舒适度焦虑