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Regulation of soybean stem growth habit:A ten-year progress report

The Crop Journal 2023年第6期11卷 1642-1648页

作者： Shang-Shang Xiong dan-dan guo Zhao Wan Le Quan Wen-Tian Lu Yongguo Xue Baohui Liu Hong Zhai State Key Laboratory of Black Soils Conservation and Utilization Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081HeilongjiangChina Key Laboratory of Soybean Molecular Design Breeding Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081HeilongjiangChina College of Life Science Northeast Agricultural UniversityHarbin 150030HeilongjiangChina College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China Institute of Soybean Research Heilongjiang Provincial Academy of Agricultural SciencesHarbin 150086HeilongjiangChina Innovative Center of Molecular Genetics and Evolution School of Life SciencesGuangzhou UniversityGuangzhou 510006GuangdongChina

Stem growth habit dictates plant architecture and influences flowering and podding(seed setting),making it an essential morphological and breeding agronomic trait of soybean(Glycine max).Stem growth habit in soybean is affected by photoperiod and environment and is determined by genetic variation at major *** genetic analysis identified two critical loci,designated Determinacy 1(Dt1)and Determinacy 2(Dt2).Dt1 is an ortholog of Arabidopsis thaliana TERMINAL FLOWER1(TFL1)and specifies an indeterminate stem growth habit,whereas Dt2 specifies a semi-determinate growth ***-box proteins,including Dt2,SUPPRESSOR OF OVEREXPRESSION OF CO1(GmSOC1)and MADS-box genes downregulated by E1(GmMDE),repress Dt1 *** encoded by the E3 and E4 loci regulate the expression of soybean FLOWERING LOCUS T(GmFT)orthologs via circadian clock genes and E1,and GmFTs compete with Dt1 to regulate stem growth *** of the molecular mechanism underlying the regulation of stem growth habit in soybean has focused on the repression of Dt1 *** we provide an overview of progress made in elucidating the genetic and molecular bases of stem growth habit in soybean,with emphasis on the molecular components responsible for integrating photoperiodic flowering and stem growth habit.

关键词： Stem growth habit Photoperiod Soybean Molecular mechanism

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Unicentric Castleman disease was misdiagnosed as pancreatic mass:A case report

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World Journal of Clinical Cases 2022年第4期10卷 1278-1285页

作者： Hong-Yan Zhai Xin-Yuan Zhu Gui-Ming Zhou Li Zhu dan-dan guo Hao Zhang Department of Ultrasound Tianjin Medical University General HospitalTianjin 300005China Department of Cardivascular Tianjin Medical University General HospitalTianjin 300005China Department of Cardivascular Surgery Tianjin Medical University General HospitalTianjin 300005China

BACKGROUND Castleman’s disease(CD)is a lymphatic proliferative disorder of unknown cause and is rarely seen *** has been divided into unicentric and multicentric *** CD(UCD)occurs as a solitary enlarged mass and mediastinal lymph nodes are the most common *** excision has proven to be curative for *** CD(MCD)appears as a systemic disease with peripheral *** had a poor response to surgery and monoclonal antibodies with rituximab have become a research *** SUMMARY A 44-year-old woman presented with a pancreatic mass during routine physical *** had no obvious symptoms,such as fever,abdominal pain,abdominal distension,or *** examination indicated a hypoechoic mass between the body of the pancreas,left lobe of the liver and *** had a clear boundary,irregular shape,uneven echo,and no obvious blood flow *** clarify the diagnosis,contrast-enhanced ultrasound examination was performed,which showed a benign pancreatic *** or solid pseudopapillary tumor was a possible *** patient underwent further contrast-enhanced computed tomography and contrastenhanced magnetic resonance imaging,which were suggestive of solid pseudopapillary tumor or neuroendocrine *** the examinations failed to give a definitive diagnosis,and the patient underwent *** final pathological and immunohistochemical results showed that the mass was *** This case highlights when lymphadenopathy is encountered clinically,CD should be considered and a biopsy should be performed.

关键词： Castleman’s disease Lymphadenopathy Unicentric Multicentric Contrastenhanced ultrasound Case report

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Lead-free metal halide scintillator materials for imaging applications

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Science China(Information Sciences) 2024年第8期67卷 85-101页

作者： Junzhe LIN dan guo Tianrui ZHAI Department of Physics and Optoelectronic Engineering Beijing University of Technology

High-energy radiation detection and imaging technology has significant applications in highenergy physics research, medical imaging, and industrial monitoring. Lead-free metal halides exhibit exceptional potential for conducting indirect detection of high-energy radiation due to their characteristics of low toxicity, strong stability, high light yield, and large Stokes shift. This paper reviews the most recent advances in lead-free metal halide scintillator materials for X-ray imaging. Subsequently, it lists the most important parameters of scintillator performance and introduces the production procedures for single crystal, powder,and nanocrystal scintillators. Furthermore, it discusses the manufacturing of scintillator films with improved performance, focusing on large-area flexible scintillator films and the coupling with microstructures. Finally,it discusses current challenges and opportunities for enhancing X-ray imaging using lead-free metal halide scintillator materials.

关键词： lead-free metal halide scintillators imaging film luminescence

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A Local Tb Theorem for Square Functions and Parabolic Layer Potentials

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Acta Mathematica Sinica,English Series 2024年第8期40卷 1941-1966页

作者： Zhi dan WANG guo Ming ZHANG School of Physical and Mathematical Sciences Nanjing Tech UniversityNanjing 211816P.R.China Frontiers Science Center for Nonlinear Expectations Ministry of EductionResearch Center for Mathematics and Interdisciplinary SciencesShandong UniversityQingdao266237P.R.China

In this paper,we give a locally parabolic version of Tb theorem for a class of vector-valued operators with off-diagonal decay in L^(2) and certain quasi-orthogonality on a subspace of L^(2),in which the testing functions themselves are also *** an application,we establish the boundedness of layer potentials related to parabolic operators in divergence form,defined in the upper half-space Rn+2+:={(x,t,λ)∈R^(n+1)×(0,∞)},with uniformly complex elliptic,L^(∞),t,λ-independent coefficients,and satisfying the De Giorgi/Nash estimates.

关键词： Local Tb theorems Calderon-Littlewood-Paley family Parabolic layer potentials Carleson measure estimates

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Elevated serum growth differentiation factor 15 in multiple system atrophy patients:A case control study

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World Journal of Clinical Cases 2020年第12期8卷 2473-2483页

作者： Tao Yue Hui Lu Xiao-Mei Yao Xia Du Ling-Ling Wang dan-dan guo Yi-Ming Liu Department of Neurology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina Department of Gerontology Zibo Central HospitalZibo 255036Shandong ProvinceChina Department of Ophthalmology Zibo Central HospitalZibo 255036Shandong ProvinceChina Department of Gerontology Jinan Central HospitalCheeloo College of MedicineShandong UniversityJinan 250013Shandong ProvinceChina Department of Neurology Jinan Central Hospital Affiliated to Shandong UniversityJinan 250013Shandong ProvinceChina Department of Neurology Yantaishan HospitalYantai 264001Shandong ProvinceChina

BACKGROUND Multiple system atrophy(MSA) is a serious progressive neurodegenerative disease. Early diagnosis of MSA is very difficult, and diagnostic biomarkers are limited. Growth differentiation factor 15(GDF15) is involved in the differentiation and progression of the central nervous system, and is widely distributed in peripheral blood, which may be a novel biomarker for *** To determine serum GDF15 levels, related factors and their potential diagnostic value in MSA patients, compared with Parkinson’s disease(PD) patients and healthy *** A case-control study was conducted, including 49 MSA patients, 50 PD patients and 50 healthy controls. Serum GDF15 levels were measured by human enzymelinked immunosorbent assay, and the differences between the MSA, PD and control groups were analyzed. Further investigations were performed in different MSA subgroups according to age of onset, sex, clinical subtypes, diagnostic criteria, and disease duration. Receiver-operating characteristic curve analysiswas used to evaluate the diagnostic value of GDF15, especially for the differential diagnosis between MSA and *** Serum GDF15 levels were significantly higher in MSA patients than in PD patients and healthy controls(P = 0.000). Males and those with a disease duration of more than three years showed higher serum GDF15 levels(P = 0.043 and 0.000;respectively). Serum GDF15 levels may be a potential diagnostic biomarker for MSA patients compared with healthy controls and PD patients(cutoff: 470.42 pg/m L, sensitivity: 85.7%, specificity: 88.0%;cutoff: 1075.91 pg/m L, sensitivity:51.0%, specificity: 96.0%;respectively).CONCLUSION Serum GDF15 levels are significantly higher in MSA patients and provide suggestions on the etiology of MSA.

关键词： Multiple system atrophy Parkinson’s disease Serum growth differentiation factor 15 Biomarker Receiver-operating characteristic curve Neurodegenerative disease

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Difluoromethyl phenoxathiinium salt: A new general and versatile difluoromethylating reagent with divergent ·CF_(2)H, CF_(2)H^(+), and :CF_(2) reactivities

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Science China Chemistry 2024年第3期67卷 953-962页

作者： Yuan-Qing Gu Hong-Xin Long dan-dan Zhang Mei-Feng Ruan guo-Kai Liu School of Pharmacy Shenzhen University Medical SchoolShenzhen UniversityShenzhen 518055China

Development of practical and versatile electrophilic difluoromethylating reagent is still a grand challenge so far due to its inherent instability or low ***,we report the design and synthesis of difluoromethyl phenoxathiinium tetrafluoroborate(PT-CF_(2)H^(+)BF_(4)^(-)) as a novel difluoromethylating reagent,which proves to be a bench-stable,general,powerful and versatile reagent with divergent·CF_(2)H,CF_(2)H^(+),and:CF_(2) *** use of this reagent,we demonstrated a vast array of difluoromethyl radical transfer reactions via diverse pathways involving photocatalyst-free visible-light induction,visible-light photoredox catalysis and visible-light mediation single electron transfer of EDA ***,the green and highly effective CF_(2)H^(+) and:CF_(2) transfer reactions were also readily accomplished.

关键词： difluoromethyl phenoxathiinium salt versatile difluoromethylating reagent difluoromethyl radical difluoromthyl cation difluorocarbene

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Association between nutritional and physical factors and anemia among schoolchildren aged 5 to 11 years in Beijing

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Chinese Medical Journal 2021年第13期134卷 1629-1631页

作者： Ying-Jie Yu Ce Lu Xiao-Hui Yu dan-dan guo Hong Li Ke-Ji Li Yao Zhao Hui Wang Department of Nutrition and Food Hygiene Beijing Center for Disease Prevention and ControlBeijing Research Center for Preventive MedicineBeijing 100013China Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjingJiangsu 211161China Department of Nutrition and Food Hygiene School of Public HealthPeking UniversityBeijing 100191China

To the Editor:Previous studies paid less attention on the reasons of anemia in schoolchildren,particularly in a relatively well-off area,which might hamper policy design for anemia ***,the present study would explore the reasons for anemiain schoolchildren aged 5to 11 years in Beijing based on personal data including dietary intake and serum biomarkers of nutrients.

关键词： anemia intake dietary

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The electroweak monopole–antimonopole pair in the standard model

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Communications in Theoretical Physics 2024年第3期76卷 113-119页

作者： dan Zhu Khai-Ming Wong guo-Quan Wong School of Physics Universiti Sains Malaysia11800 USMPenangMalaysia

We present the first numerical solution that corresponds to a pair of Cho–Maison monopoles and antimonopoles(MAPs) in the SU(2) × U(1) Weinberg–Salam(WS) *** monopoles are finitely separated,while each pole carries a magnetic charge ±4π/*** positive pole is situated in the upper hemisphere,whereas the negative pole is in the lower *** Cho–Maison MAP is investigated for a range of Weinberg angles,0.4675≤ tan θ_(W)≤10,and Higgs self-coupling,0 ≤ β ≤ *** magnetic dipole moment(μm) and pole separation(d_(z)) of the numerical solutions are calculated and *** total energy of the system,however,is infinite due to point singularities at the locations of monopoles.

关键词： magnetic monopole Cho-Maison monopole Weinberg-Salam model

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Comparative analysis of frictional behavior and mechanism of molybdenum ditelluride with different structures

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Friction 2024年第1期12卷 110-119页

作者： Lina ZHANG Xinfeng TAN Jianguo JIAO dan guo Jianbin LUO State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing 100084China

Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have layered structures with excellent tribological *** the energy difference between hexagonal-molybdenum ditelluride(2H-MoTe_(2))and distorted octahedral-molybdenum ditelluride(1T′-MoTe_(2))is very small among the transition metal dichalcogenides(TMDCs),MoTe_(2) becomes one of the most promising candidates for phase *** our experiment,we found that the friction force and friction coefficient(COF)of 2H-MoTe_(2) were an order of magnitude smaller than those of 1T′-MoTe_(2) by the atomic force microscope(AFM)*** friction difference between 1T′-MoTe_(2) and 2H-MoTe_(2) was further verified in molecular dynamics(MD)*** density functional theory(DFT)calculations suggest that the friction contrast is related to the difference in sliding energy barrier of the potential energy surface(PES)for a tip sliding across the *** PES obtained from the DFT calculation indicates that the maximum energy barrier and the minimum energy path(MEP)energy barrier of 2H-MoTe_(2) are both smaller than those of 1T′-MoTe_(2),which means that less energy needs to be dissipated during the sliding *** difference in energy barrier of the PES could be ascribed to its larger interlayer spacing and weaker Mo–Te interatomic interactions within the layers of 2H-MoTe_(2) than those of 1T′-MoTe_(2).The obvious friction difference between 1T′-MoTe_(2) and 2H-MoTe_(2) not only provides a new non-destructive means to detect the phase transition by the AFM,but also provides a possibility to tune friction by controlling the phase transition,which has the potential to be applied in extreme environments such as space lubrication.

关键词： friction two-dimensional(2D)materials distorted octahedral-molybdenum ditelluride(1T′-MoTe_(2)) hexagonal-molybdenum ditelluride(2H-MoTe_(2)) phase transition

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Three-dimensional cell-based strategies for liver regeneration

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BIOCELL 2024年第7期48卷 1023-1036页

作者： dan guo XI XIA JIAN YANG Liver Transplant Center Transplant CenterWest China HospitalSichuan UniversityChengdu610041China Frontiers Medical Center Tianfu Jincheng LaboratoryChengdu610212China

Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern *** recent years,the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical *** review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver ***,we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver ***,we explored the challenges in transitioning these innovative strategies from preclinical studies to clinical *** collective insights presented herein highlight the signiﬁcance of 3D cell-based strategies as a transformative paradigm for liver regeneration and improved patient care.

关键词： Three-Dimensional Liver regeneration Organoids Stem cells Cell therapy

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