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医护人员工作压力在工作压力源与压力成瘾之间的中介作用

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海南医学 2024年第16期35卷 2376-2380页

作者：刘小燕杨丽浇王选燕贞王小丹海南医科大学公共卫生学院海南海口570100

目的探讨工作压力在医护人员工作压力源与压力成瘾之间的中介作用。方法使用多阶段随机抽样方法于2020年11月1日至30日抽取海口市5家三甲医院1543名医护人员作为研究对象。采用一般情况调查表、工作压力源量表、医护人员压力量表、工作... 详细信息

目的探讨工作压力在医护人员工作压力源与压力成瘾之间的中介作用。方法使用多阶段随机抽样方法于2020年11月1日至30日抽取海口市5家三甲医院1543名医护人员作为研究对象。采用一般情况调查表、工作压力源量表、医护人员压力量表、工作压力成瘾量表进行问卷调查。采用Pearson相关分析工作压力源、工作压力与压力成瘾间的相关性。采用Amos26.0软件构建工作压力源、工作压力及压力成瘾之间的结构方程模型,采用Process插件的Model 4分析工作压力在工作压力源与压力成瘾间的中介作用,同时采用Bootstrap法对中介作用进行检验。结果经Pearson相关性分析及结构方程模型分析结果显示,压力成瘾与工作压力源呈正相关(r=0.382,P<0.001),压力成瘾与工作压力呈正相关(r=0.465,P<0.001),工作压力源与工作压力呈正相关(r=0.627,P<0.001);工作压力源直接和间接作用压力成瘾,效应值分别为0.08和0.465,工作压力直接作用压力成瘾,效应值为0.681。经中介模型分析结果显示,工作压力在工作压力源与压力成瘾之间起中介作用,中介效应值为0.233。结论工作压力源直接和间接作用压力成瘾,工作压力直接作用压力成瘾,工作压力在工作压力源与压力成瘾间起中介作用。

关键词：医护人员工作压力源工作压力压力成瘾中介作用

The Boundedness of Marcinkiewicz Integrals on Grand Variable Herz Spaces

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Analysis in Theory and Applications 2023年第2期39卷 163-177页

作者： dan xiao Lisheng Shu College of Humanities Anhui Professional College of ArtHefeiAnhui 230001China School of Mathematics and Statistics Anhui Normal UniversityWuhuAnhui 241003China

Under some natural regularity assumptions on the exponent function,we obtain the boundedness of Marcinkiewicz integralsμ,μ_(s)^(ρ)andμ_(λ)^(*,ρ)on grand variable Herz *** results enrich and improve some previous... 详细信息

关键词： Marcinkiewicz integrals Herz spaces variable exponent grand spaces

我国司法鉴定团体标准治理的现实困境和路径选择

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标准科学 2024年第1期 14-23页

作者：白田宇邵景文何晓丹司法鉴定科学研究院上海市法医学重点实验室司法部司法鉴定重点实验室上海市司法鉴定专业技术服务平台

2018年,新修订的《标准化法》正式确立了团体标准的法律地位。经过几年的快速发展,我国团体标准政策体系逐步完善,团体标准快速涌现。然而,我国司法鉴定领域团体标准的管理和运行仍处于初级阶段,存在顶层设计缺失、裂化和市场化风险以... 详细信息

2018年,新修订的《标准化法》正式确立了团体标准的法律地位。经过几年的快速发展,我国团体标准政策体系逐步完善,团体标准快速涌现。然而,我国司法鉴定领域团体标准的管理和运行仍处于初级阶段,存在顶层设计缺失、裂化和市场化风险以及未形成有效闭环等问题。司法鉴定的本质属性是法律性和科学性的有机统一,司法鉴定标准作为鉴定人进行专业鉴别和判断并出具司法鉴定意见的依据,应具有统一性、科学性、客观性和公认性。本文基于司法鉴定标准统一性的“限制性”要求与团体标准的“鼓励性”制定、标准的“供给”和“适用”之间的冲突,探讨司法鉴定团体标准治理路径,旨在促进司法鉴定团体标准高质量发展。

关键词：司法鉴定团体标准标准化治理路径

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Exome sequencing analysis identifies novel homozygous mutation in ABCA4 in a Chinese family with Stargardt disease

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International Journal of Ophthalmology(English edition) 2020年第4期13卷 671-676页

作者： xiao-dan Hao Ying Liu Bao-Wei Li Wei Wu xiao-Wen Zhao Institute for Translational Medicine College of MedicineQingdao UniversityQingdao 266021Shandong ProvinceChina State Key Laboratory Cultivation Base Shandong Provincial Key Laboratory of OphthalmologyShandong Eye InstituteShandong First Medical University&Shandong Academy of Medical SciencesQingdao 266071Shandong ProvinceChina

AIM: To identify the disease-associated mutations in a Chinese Stargardt disease(STGD) family, extend the existing spectrum of disease-causing mutations and further define the genotype-phenotype ***: A Chinese STGD family and 200 normal controls were collected. Whole exome sequencing(WES) and bioinformatics analysis were performed to find the pathogenic gene mutation. Physico-chemical parameters of mutant and wildtype proteins were computed by Prot Param tool. Domains analysis was performed by SMART online software. HOPE online software was used to analyze the structural effects of mutation. Immunofluorescence, quantitative real-time polymerase chain reaction and Western blotting were used for expression ***: Using WES, a novel homozygous mutation(NM_000350: c.G3190 C, p.G1064 R) in ABCA4 gene was identified. This mutation showed co-segregation with phenotype in this family. It was not found in the 200 unrelated health controls and absent from any databases. It was considered "Deleterious" as predicted by five function prediction softwares, and was highly conserved during evolution. ABCA4 was expressed highly in the human eye and mouse retina. The p.G1064 R was located in AAA domain, may force the local backbone into an incorrect conformation, disturb the local structure, and reduce the activity of ATPase resulting in the disease pathology. CONCLUSION: We define a novel pathogenic mutation(c.G3190 C of ABCA4) of STGD. This extends the existing spectrum of disease-causing mutations and further defines the genotype-phenotype correlations.

关键词： Stargardt disease whole-exome sequencing ABCA4 novel mutation retina

Rebirth after death: forest succession dynamics in response to climate change on Gongga Mountain, Southwest China

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Journal of Mountain Science 2018年第8期15卷 1671-1681页

作者： CHENG Gen-wei LU Xu-yang WANG xiao-dan SUN Jian Institute of Mountain Hazards and Environment Chinese Academy of Sciences Key Laboratory of Mountain Surface Processes and Ecological Regulation Chinese Academy of Sciences Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences

Global climate change is having long-term impacts on the geographic distribution of forest species. However, the response of vertical belts of mountain forests to climate change is still little known. The vertical distribution of forest vegetation(vertical vegetation belt) on Gongga Mountain in Southwest China has been monitored for 30 years. The forest alternation of the vertical vegetation belt under different climate conditions was simulated by using a mathematical model GFSM(the Gongga Forest Succession Model). Three possible Intergovernmental Panel on Climate Change(IPCC) climate scenarios(increase of air temperature and precipitation by 1.8℃/5%, 2.8℃/10% and 3.4℃/15% for B_1, A_1B and A_2 scenarios, respectively) were chosen to reflect lower, medium and higher changes of global climate. The vertical belts of mountainous vegetation will shift upward by approximately 300 m, 500 m and 600 m in the B_1, A_1B and A_2 scenarios, respectively, according to the simulated results. Thus, the alpine tree-line will move to a higher altitude. The simulation also demonstrated that, in a changing climate, the shift in the vegetation community will be a slow and extended process characterized by two main phases. During the initial phase, trees of the forest community degrade or die, owing to an inability to adapt to a warmer climate. This results in modest environment for the introduction of opportunistic species, consequently, the vegetation with new dominant tree species becomes predominant in the space vacated by the dead trees at the expense of previously dominated original trees as the succession succeed and climate change advance. Hence, the global climate change would dramatically change forest communities and tree species in mountainous regions because that the new forest community can grow only through the death of the original tree. Results indicated that climate change will cause the change of distribution and composition of forest communities on Gongga Mountain, a

关键词： Climate change Forest Succession Model Forest vegetation Vertical vegetation belt Forest succession Gongga Mountain

Fabrication of Porous Nitrogen-Doped Carbon Materials as Anodes for High-Performance Lithium Ion Batteries

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Chinese Journal of Chemistry 2015年第11期33卷 1293-1302页

作者： Junke Ou Lin Yang YongzhiZhang Li Chen Yong Guo dan xiao School of Basic Medical Sciences & Nursing Chengdu University Chengdu Sichuan 610000 China Institute of New Energy and Low-Carbon Technology Sichuan University Chengdu Sichuan 610207 China College of Chemistry Sichuan University Chengdu Sichuan 610065 China

The hierarchical porous nitrogen-doped carbon materials （HNCs） were prepared by using nitrogen containing gelatin as the carbon source and nano-silica obtained by a simple flame synthesis approach as the template. All of the as-obtained HNCs show much higher Li storage capacity as compared with commercial graphite. Specifically, HNC-700 with biggest micropore volume and highest nitrogen content exhibited optimal reversible capacities of 1084 mAh·g^-1 at the current density of 37.2 mA·g^-1 （0.1 C） and 309 mAh·g^-1 even at 3.72 A·g^-1 （10 C）. This result suggests that HNCs should be a promising candidate for anode materials in high-rate lithium ion batteries （LIBs）.

关键词： HNCs gelatin micropore volume nitrogen content capacities

Studies on the Catalytic Properties of Magnesia Supported on γ-Alumina

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Chemical Research in Chinese Universities 2002年第2期18卷 196-199页

作者： JIAO Qing ze ZHAO Yun LI xiao dan EVANS DG DUAN Xue Key Laboratory of Science and Technology of Controllable Chemical Reactions Ministry of EducationBeijing University of Chemical TechnologyBeijing 100029P.R.China

We have shown that MgO can be dispersed on γ Al 2O 3 with different loadings. The observed dispersion capacity of MgO on the surface of γ Al 2O 3 is higher than the theoretical monolayer dispersion value. The surface area and the maximum in the pore size distribution gradually decrease with the increase in MgO content at low loadings. The surface area and the maximum in the pore size distribution of MgO/ γ Al 2O 3 decrease more rapidly when the MgO content is large because the pores of γ Al 2O 3 become blocked. When small amounts of MgO are dispersed on the surface of γ Al 2O 3, the catalyst is very active and shows a good selectivity for the synthesis of glycol ethers.

关键词： Magnesia Alumina Dispersion Glycol ether

Tempering Process to Improve Hardness Uniformity of Plastic Mould Steel

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Journal of Iron and Steel Research International 2012年第12期19卷 53-58页

作者： MIN Yong-an ZHOU Quan LUO Yi LI dan WU xiao-chun School of Materials Science and Engineering Shanghai University Shanghai 200072 China

A new design of copper-bearing non-quenched plastic mold steel is presented and explained. Two kinds of microstrueture can be obtained from this new type copper-bearing steel via cooling with different cooling rates, bain- ite and a mixed microstructure consisting of ferrite and bainite. It is found that, after proper tempering process, the hardness will be increased. Moreover, the hardness difference between different microstructures will be reduced. For further investigation, the samples tempered at different temperatures were examined by XRD and 3PAP （three di- mensional atom probe） analysis. Results show that the improvement is contributed mainly by the precipitation of Cu phase and transformation of residual austenite.

关键词： plastic mould steel tempering process Cu precipitation residual austenite

Effects of rock fragments on yak dung greenhouse gas emissions on the Qinghai-Tibetan Plateau

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Journal of Mountain Science 2016年第11期13卷 2006-2014页

作者： DU Zi-yin WANG xiao-dan LIU Xiu-ping CAI Yan-jiang Key Laboratory of Mountain Surface Processes and Ecological Regulation Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu 610041China University of Chinese Academy of Sciences Beijing 100049China Center for Agricultural Resources Research Institute of Genetics and Developmental BiologyChinese Academy of SciencesShijiazhuang 050021China

Dung deposition is an important pathway of nutrient return and redistribution in alpine grasslands of the Qinghai-Tibetan *** date,information on the greenhouse gas emissions of yak dung on alpine grasslands,especially where there are large amounts of rock fragments,is *** aim,therefore,was to evaluate variations in N_2O,CH_4,and CO_2 emissions from yak dung(CCD),and compare it to dung placed on rock fragments(RCD),alpine steppe soil(CSD),and a soil and rock fragment mixture(RSD) over a 30-day incubation *** results showed that the total N_2O emissions from treatments without soil were significantly(P < 0.05) lower than those from treatments with *** highest total CH_4 emissions were detected in the CSD treatment,while CH_4 losses from treatments without rock fragments were significantly(P < 0.05) greater than those with rock *** total CO_2 emissions from the RSD treatment was 6.30%–12.0% lower than those in the other three *** soil beneath yak dung pats elevated the globalwarming potential(GWP),while the addition of rock fragments to the soil significantly(P < 0.05) decreased the GWP by reducing emissions of the three greenhouse *** therefore suggest that interactions between rock fragments and alpine steppe soil are effective in decreasing yak dung greenhouse gas *** finding indicates that rock fragments are an effective medium for reducing greenhouse gas emissions from dung pats,and more attention should therefore be paid to evaluate its ecological impact in future *** results should help guide scientific assessments of regional GHG budgets in agricultural ecosystems where the addition of livestock manure to soils with large amounts of rock fragments is common.

关键词： Rock fragments Yak dung Nitrous oxide Methane Qinghai-Tibetan Plateau