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Immunovirological Profile of HIV1 Infection in Children and Adolescents Followed at the Bangui Pediatric University Hospital

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Open Journal of Pediatrics 2024年第3期14卷 585-597页

作者： Simplice Cyriaque Kango Synthia Ningatoloum Nazita Marie Colette Nganda-Bangue Michaël dan-Houron Alexandre Manirakiza Jean Chrysostome Gody Department of The Clinique Mé dicale Infantile Raymond Max Siopathis University Children&#8217s Hospital Bangui CAR Faculty of Health Sciences (FACSS) Bangui CAR National laboratory of Clinical Biology and Public Health Bangui CAR Pasteur Institute Bangui CAR

History: Pediatric management of HIV infection in children in the Central African Republic began in 2004 with the use of fractionated adult antiretrovirals and Cotrimoxazole. It has evolved over the years with the use of pediatric forms, oral suspensions and dispersible tablets. The transition to Dolutegravir took place in 2020. The active file of our patients will grow from 78 to over 1900 today. Follow-up examinations are carried out to assess adherence to treatment. Objective: To determine the immunovirological profile and factors associated with treatment failure during follow-up of children on ART at the Bangui pediatric university hospital. Patients and Method: This was a cross-sectional, analytical study from May 30 to December 02, 2022. The study sample was drawn from a cohort of HIV-1-infected children followed up at the Bangui pediatric university hospital and on ART for three semesters who met the selection criteria. Results: The prevalence of treatment failure varied from one semester to the next. Thus, the prevalence of therapeutic failure was 20% in the first semester, 10% in the second semester and 7% in the third semester. The prevalence of virological failure was 10.28% in the first half of the year, 6.91% in the second half and 4.98% in the third. Secondly, immunological failure was 0.48% in the first half of the year, 0.32% in the second 0.64% in the third half. Finally, clinical failure was 8.82% in the first half, 4.82% in the second half, 1.92% in the third half. Socio-demographic and clinical factors associated with treatment failure were male gender (p 1000 copies/ml (p Conclusion: The occurrence of treatment failures in children is a major problem, especially in our resource-limited countries, given the challenges facing antiretroviral therapy. It is therefore necessary to carry out a study on resistance genotyping in order to propose correct management protocols, as the future of treatment programs depends on it.

关键词： Profile Immunovirological HIV/AIDS Children Bangui

藤本植物园林景观应用调查分析——以九江市为例

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陕西林业科技 2024年第2期52卷 93-97,100页

作者：吕丹丹聂谷华抚州市林业局江西抚州344000 九江学院江西九江332900

为了解九江市园林景观中藤本植物的应用情况,对九江市濂溪区、浔阳区、柴桑区、八里湖新区四个城区进行抽样实地调查,并详细记录各地点应用的藤本植物名称,应用形式,生长状况,观赏效果等.通过调查发现藤本植物在园林景观应用中存在的问... 详细信息

为了解九江市园林景观中藤本植物的应用情况,对九江市濂溪区、浔阳区、柴桑区、八里湖新区四个城区进行抽样实地调查,并详细记录各地点应用的藤本植物名称,应用形式,生长状况,观赏效果等.通过调查发现藤本植物在园林景观应用中存在的问题,并对九江藤本植物的应用及发展提出合理性建议,以期提高九江市的绿化覆盖率、增加城市绿量.

关键词：藤本植物九江市园林景观调查分析

山羊绒、绵羊毛与其他特种动物纤维及其混合物含量的测定方法比较

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印染助剂 2024年第5期41卷 53-56页

作者：吕丹任海平武汉产品质量监督检验所湖北武汉430048

GB/T 40905.1—2021《纺织品山羊绒、绵羊毛、其他特种动物纤维及其混合物定量分析第1部分:光学显微镜法》于2021年10月11日发布,2022年5月1日实施,是继GB/T 16988—2013《特种动物纤维与绵羊毛混合物含量的测定》之后发布的第二个使用... 详细信息

GB/T 40905.1—2021《纺织品山羊绒、绵羊毛、其他特种动物纤维及其混合物定量分析第1部分:光学显微镜法》于2021年10月11日发布,2022年5月1日实施,是继GB/T 16988—2013《特种动物纤维与绵羊毛混合物含量的测定》之后发布的第二个使用光学显微镜鉴别山羊绒、绵羊毛与其他特种动物纤维的国家推荐性标准。该标准在仪器设备、样品的抽取、试样的制备、褪色方法和资料性附录等方面进行了调整和变动。为方便检验员更好地理解检验标准,比较GB/T 40905.1—2021和GB/T 16988—2013两种检测方法的主要差异。

关键词：山羊绒特种动物纤维表面形态特征

Temporal and Spatial Distribution of the late Devonian (Famennian) Strata in the Northwestern Border of the Junggar Basin, Xinjiang, Northwestern China

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Acta Geologica Sinica(English Edition) 2017年第4期91卷 1413-1437页

作者： MA Xueping ZHANG Meiqiong ZONG Pu ZHANG Yubo lü dan The Key laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space Sciences Peking University Beijing 100871 China Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 China

The base of the Saerba Member （Mbr） of the Hongguleleng Formation （Fm.） probably lies in the Famennian Palmatolepis crepida Zone; the longkou Mbr is probably a sedimentary wedge that thins out northwards; the Duguer Mbr has an approximate age from the upper part of the Pa. marginifera Zone or the lower Pa. rugosa trachytera Zone through the top of the Pa. perlobata postera Zone; the Wulan Mbr has an age approximately corresponding to the whole Pa. gracilis expansa Zone. In the Bulongguoer section, the lower Mbr of the Hongguleleng Fro. corresponds to Famennian Pa. crepida Zone through Pa. marginifera Zone; the Middle Mbr probably ranges from the Pa. r. trachytera Zone through the Pa. g. expansa Zone. The basal Namu Mbr of the Heishantou Fm. is probably the product during and after the Hangenberg Event in the upper part of the Siphonodellapraesulcata Zone, which is still within the Devonian. In this context, the underlying Chasi Mbr may approximately correspond to the lower part of the S. praesulcata Zone （before the Hangenberg Event）. lateral distribution of strata indicates that the Upper Devonian in the Gennaren and Saerba areas each constitutes a structure of syncline, which differs from the previous recognition of a monocline structure.

关键词： Junggar Bulongguoer Hongguleleng Formation Heishantou Formation "Hebukehe"Formation Xinjiang

进阶式肺康复在经鼻高流量氧疗患者中的应用研究

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中华护理杂志 2024年第17期59卷 2053-2061页

作者：吕丹赵莹贺艳刘青宋福娟李萌张馨月王晓萍天津市第三中心医院呼吸科 300170 天津市第三中心医院护理部 300170 天津市第三中心医院ICU 300170

目的探讨进阶式肺康复在经鼻高流量氧疗(high-flow nasal cannula oxygen therapy,HFNC)患者中的应用效果。方法采用便利抽样法,选取天津市某三级甲等综合医院呼吸科、ICU、冠心病监护室等在2023年1月—6月收治的40例HFNC患者为试验组,2... 详细信息

目的探讨进阶式肺康复在经鼻高流量氧疗(high-flow nasal cannula oxygen therapy,HFNC)患者中的应用效果。方法采用便利抽样法,选取天津市某三级甲等综合医院呼吸科、ICU、冠心病监护室等在2023年1月—6月收治的40例HFNC患者为试验组,2022年6月—12月收治的40例HFNC患者为对照组,试验组以信息-动机-行为技巧(informa-tion-motivation-behavioral skills,IMB)模型为理论基础,实施包括病情稳定期、出院准备期、居家康复期的进阶式肺康复,且通过随访平台进行居家肺康复的依从性管理;对照组实施常规肺康复及居家随访。比较干预前、出院后第2个月、出院后第6个月两组呼吸困难程度、6 min步行距离、运动自我效能、生活质量,以及出院后6个月内两组居家肺康复依从性。结果重复测量方差分析显示,两组呼吸困难程度、6 min步行距离、运动自我效能、生活质量比较,时间与组间均存在交互效应(P<0.05);简单效应分析显示,出院后第2、6个月,试验组呼吸困难程度、6 min步行距离、运动自我效能、生活质量均优于对照组(P<0.05)。出院后6个月内,试验组居家肺康复依从性优于对照组,差异有统计学意义(P<0.05)。结论基于IMB模型的进阶式肺康复能改善HFNC患者的呼吸系统症状,提高其运动自我效能和居家肺康复依从性,增强运动耐力和提高生活质量。

关键词：经鼻高流量氧疗肺康复智随访信息-动机-行为技巧模型康复护理

Strategic comparison of membrane-assisted and membrane-less water electrolyzers and their potential application in direct seawater splitting(DSS)

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Green Energy & Environment 2023年第4期8卷 989-1005页

作者： Abdul Malek Xu lu Paul R.Shearing dan J.l.Brett Guanjie He Clean Combustion Research Center(CCRC) Physical Science and Engineering Division(PSE)King Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia KAUST Solar Center(KSC) Physical Science and Engineering Division(PSE)King Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia School of Engineering and Materials Science Queen Mary University of LondonMile End RoadLondon E14NSUK Department of Chemical Engineering University College London(UCL)Gower StLondon WC1E 6BTUnited Kingdom

Electrocatalytic splitting of water by means of renewable energy as the electricity supply is one of the most promising methods for storing green renewable energy as hydrogen. Although two-thirds of the earth’s surface is covered with water, there is inadequacy of freshwater in most parts of the world. Hence, splitting seawater instead of freshwater could be a truly sustainable alternative. However, direct seawater splitting faces challenges because of the complex composition of seawater. The composition, and hence, the local chemistry of seawater may vary depending on its origin, and in most cases, tracking of the side reactions and standardizing and customizing the catalytic process will be an extra challenge. The corrosion of catalysts and competitive side reactions due to the presence of various inorganic and organic pollutants create challenges for developing stable electro-catalysts. Hence, seawater splitting generally involves a two-step process, i.e., purification of seawater using reverse osmosis and then subsequent fresh water splitting. However, this demands two separate chambers and larger space, and increases complexity of the reactor design. Recently, there have been efforts to directly split seawater without the reverse osmosis step. Herein, we represent the most recent innovative approaches to avoid the two-step process, and compare the potential application of membrane-assisted and membrane-less electrolyzers in direct seawater splitting(DSS). We particularly discuss the device engineering, and propose a novel electrolyzer design strategies for concentration gradient based membrane-less microfluidic electrolyzer.

关键词： Electrocatalytic seawater splitting Direct seawater splitting Osmosis Concentration cells Membrane-less electrolyzer Microfluidic electrolyzer

low fermentable oligosaccharides, disaccharides,monosaccharides, and polyols diet in children

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World Journal of Clinical Cases 2019年第18期7卷 2666-2674页

作者： Ioana Fodor Sorin Claudiu Man dan l Dumitrascu 3^rd Pediatric Department Iuliu Hatieganu University of Medicine and PharmacyCluj-Napoca 400006Romania 2^nd Medical Department Iuliu Hatieganu University of Medicine and PharmacyCluj-Napoca 400006Romania

Irritable bowel syndrome (IBS) is a lifelong condition with a high prevalence among children and adults. As the diet is a frequent factor that triggers the symptoms, it has been assumed that by avoiding the consumption of fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP), the symptoms might be improved. Therefore, in the past decade, low FODMAP diet has been intensively investigated in the management of IBS. The capacity of FODMAPs to trigger the symptoms in patients with IBS was related to the stimulation of mechanoreceptors in the small and large intestine. This stimulation appears as a response to a combination of increased luminal water (the osmotic effect) and the release of gases (carbon dioxide and hydrogen) due to the fermentation of oligosaccharides and malabsorption of fructose, lactose and polyols. Numerous studies have been published regarding the efficacy of a low FODMAP diet compared to a traditional diet in releasing the IBS symptoms in adults, but there are only a few studies in the juvenile population. The aim of this review is to analyze the current data on both low FODMAP diet in children with IBS and the effects on their nutritional status and physiological development, given the fact that it is a restrictive diet.

关键词： low fermentable oligosaccharides Disaccharides Monosaccharides Polyols Diet Children Irritable bowel syndrome Symptom

What are the limiting Environmental Factors for the Evolution of Early Eukaryotic Diversity?

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Journal of Earth Science 2023年第4期34卷 1313-1314页

作者： Shuichang Zhang Xiaomei Wang Huajian Wang Qing Tang Fenglian Zhang dan lü Research Institute of Petroleum Exploration&Development China National Petroleum CorporationBeijing 100083China School of EarthSciences and Engineering NanjingUniversityNanjing 210023China School of Ocean Sciences China University of Geosciences BeijingBeijing 100083China

Exploring the mysteries of life is an eternal frontier of science. Containing complex and diverse organisms on the surface of the Earth is one of the most crucial characteristics that distinguish the Earth from other planets in the Solar system. Almost all animals, plants, and fungi that can be seen with the naked eye belong to eukaryotes。

关键词： Earth Solar planet

Distribution Control Centers in the US and Europe:Commonalities,Differences,and lessons

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 259-268页

作者： Subramanian Vadari Izudin Dzafic dan'l Koch Ryan Murphy daniel Hayes Jr. Tarik Donlagic Modem Grid Solutions New YorkUSA University of Sarajevo Faculty of Electrical EngineeringSarajevoBosnia and Herzegovina R.Murphy are with Puget Sound Energy BellevueUSA Commonwealth Edison ChicagoUSA Siemens AG ErlanglenGermany

The distribution control center(DCC)has evolved from a sideshow in the traditional distribution service center to a major centerpiece of the utility moving into the decentralized ***,this is the place where much of the action is happening due to new forms of energy that are coining into the distribution *** creates the flexibility of operation and in-creased complexity due to the need for increased coordination between the transmission control center and ***,the US and European utilities have adapted to this change in very different ***,we describe the research works done in a DCC and their evolutions from the perspectives of major US utilities,and those enhanced by the European perspective focusing on the coordination of distribution system operator and transmission system operator(DSO-TSO).We pres-ent the insights into the systems used in these control centers and the role of vendors in their *** this paper,we present the perspectives of challenges,operational capabilities,and the involvement of various parties who will be re-sponsible to make the transition *** differences are pointed out on how distribution operations are conducted between the US and Europe.

关键词： Distribution control center(DCC) power system operation distributed generation asset flexibility volt-var optimization and control.