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Journal of Biosciences and Medicines 2015年第11期3卷 33-41页

作者： Motoki Sakai daming wei Faculty of Policy Informatics Chiba University of Commerce Chiba Japan Tohoku University Graduate School of Medicine Miyagi Japan

Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder. It has been reported that approximately 40% of patients with moderate or severe OSAS die within the first eight years of disease. In hospitals, OSAS is inspected using polysomnography, which uses a number of sensors. Because of the cumbersome nature of this polysomnography, an initial OSAS screening is usually conducted. In recent years, OSAS screening techniques using Holter electrocardiogram (ECG) have been reported. However, the techniques so far reported cannot perform an OSAS severity assessment. The present study presents a new method to distinguish the obstructive sleep apnea (OSA) and non-OSA epochs at one-second intervals based on the Apnea Hypopnea Index assessment, defined as the duration of continuous apnea. In the proposed method, the time-frequency components of the heart rate variability and three ECG-derived respiration signals calculated by the complex Morlet wavelet transformation are adopted as features. A support vector machine is employed for classification. The proposed method is evaluated using three eight-hour ECG recordings containing OSA episodes from three subjects. As a result, the sensitivity and specificity of classification are found to reach approximately 90%, a level suitable for OSAS screening in clinical settings.

关键词： Obstructive Sleep Apnea Syndrome Heart Rate Variability ECG-Derived Respiration Complex Morlet Wavelet Transformation Support Vector Machine

罗哌卡因联合针刺下髎、长强穴治疗混合痔患者术后肛门坠胀及并发症临床研究

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辽宁中医杂志 2024年第1期51卷 176-178页

作者：赵艳魏大明戴红杨永晖安徽省中西医结合医院安徽合肥230000

目的探讨低浓度罗哌卡因与针刺下髎穴、长强穴用于混合痔术后对患者肛门坠胀和并发症的影响。方法选取医院2020年7月—2021年7月收治的混合痔患者160例,随机均分为两组,对照组给予低浓度罗哌卡因麻醉,观察者在此基础上针刺下髎穴和长强... 详细信息

目的探讨低浓度罗哌卡因与针刺下髎穴、长强穴用于混合痔术后对患者肛门坠胀和并发症的影响。方法选取医院2020年7月—2021年7月收治的混合痔患者160例,随机均分为两组,对照组给予低浓度罗哌卡因麻醉,观察者在此基础上针刺下髎穴和长强穴,观察者术后两组患者症状消退时间、肛门坠胀程度、炎性因子和疼痛因子水平及并发症的发生率。结果观察组患者疼痛、肛门坠胀及水肿消退时间明显低于对照组(P<0.05);不同时间的肛门坠胀评分有差异(P<0.05),与对照组比较,观察组肛门坠胀评分较低(P<0.05),观察组肛门坠胀评分变化趋势有差异(P<0.05);观察组患者肿瘤坏死因子-α(TNF-α)、白细胞介素-17(IL-17)、P物质(SP)、5-羟色胺(5-HT)水平明显低于对照组(P<0.05);观察组并发症的发生率明显低于对照组(P<0.05)。结论混合痔患者低浓度罗哌卡因麻醉术后采用与针刺下髎穴、长强穴联合治疗能有效调节机体炎性因子和疼痛因子水平,缓解肛门坠胀,缩短症状消退时间,并有助于降低术后并发症的发生率。

关键词：混合痔罗哌卡因针刺治疗肛门坠胀长强穴下髎穴

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Enhanced cycle stability of aprotic Li-O_(2) batteries based on a self-defensed redox mediator

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Chinese Chemical Letters 2024年第3期35卷 449-452页

作者： Guiru Sun Yan Wang daming Yang Zexu Zhang wei Lu Ming Feng Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education Jilin Normal UniversityChangchun 130103China College of Information Technology Jilin Engineering Research Center of Optoelectronic Materials and DevicesJilin Normal UniversitySiping 136000China

LiBr as a promising redox mediator(RM)has been applied in Li-O_(2)batteries to improve oxygen evolution reaction kinetics and reduce ***,the redox shuttle of Br_(3)^-can induce the unexpected reactions and thus cause the degradation of LiBr and the corrosion of Li anode,resulting in the poor cyclability and the low round-trip ***,MgBr_(2)is firstly employed with dual functions for Li-O_(2)batteries,which can serve as a RM and a SEI film-forming *** Br^(–)is beneficial to facilitating the decomposition of Li_(2)O_(2)and thus decreasing the ***,a uniform SEI film containing Mg and MgO generates on Li anode surface by the in-situ spontaneous reactions of Mg^(2+)and Li anode in an O_(2)environment,which can suppress the redox shuttle of Br_(3)^-and improve the interface stability of Li anode and *** from these advantages,the cycle life of Li-O_(2)battery with MgBr_(2)electrolyte is significantly extended.

关键词： MgBr_(2) Redox mediator Redox shuttle Li anode SEI film

Gamma-ray Bursts:Progresses at Purple Mountain Observatory

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Bulletin of the Chinese Academy of Sciences 2011年第3期25卷 192-194页

作者： wei daming FAN Yizhong Purple Mountain Observatory CAS Nanjing 210008 Key Laboratory of Dark Matter and Space Astronomy CAS Nanjing 210008

A gamma-ray burst （GRB） is an extremely luminous flash of gamma rays that occurs as the result of an explosion, and is thought to be associated with the formation of a black hole. Most GRBs are billions of light years away from Earth, implying that the explosions are both extremely energetic （a typical burst releases as much energy in a few seconds as the Sun will in its entire 10-billion-year lifetime） and extremely rare （a few per galaxy per million years）. Researches on GRBs have attracted wide attention. For experts on accretion disks,

关键词：伽玛射线爆发紫金山天文台 GRB Sun 吸积盘爆炸黑洞光年

MOF‐derived 1D/3D N‐doped porous carbon for spatially confined electrochemical CO2 reduction to adjustable syngas

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Carbon Energy 2024年第8期6卷 1-13页

作者： wei Zhang Hui Li daming Feng Chenglin Wu Chenghua Sun Baohua Jia Xue Liu Tianyi Ma Key Laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials Institute of Clean Energy ChemistryCollege of ChemistryLiaoning UniversityShenyangLiaoningChina School of Science RMIT UniversityMelbourneVictoriaAustralia School of Pharmaceutical and Chemical Engineering Taizhou UniversityTaizhouZhejiangChina Department of Chemistry and Biotechnology Swinburne University of TechnologyHawthornVictoriaAustralia

Electrochemical reduction of CO_(2)to syngas(CO and H_(2))offers an efficient way to mitigate carbon emissions and store intermittent renewable energy in ***,the hierarchical one‐dimensional/three‐dimensional nitrogen‐doped porous carbon(1D/3D NPC)is prepared by carbonizing the composite of Zn‐MOF‐74 crystals in situ grown on a commercial melamine sponge(MS),for electrochemical CO_(2)reduction reaction(CO_(2)RR).The 1D/3D NPC exhibits a high CO/H_(2)ratio(5.06)and CO yield(31 mmol g^(−1)h^(−1))at−0.55 V,which are 13.7 times and 21.4 times those of 1D porous carbon(derived from Zn‐MOF‐74)and N‐doped carbon(carbonized by MS),*** is attributed to the unique spatial environment of 1D/3D NPC,which increases the adsorption capacity of CO_(2)and promotes electron transfer from the 3D N‐doped carbon framework to 1D carbon,improving the reaction kinetics of CO_(2)*** results and charge density difference plots indicate that the active site of CO_(2)RR is the positively charged carbon atom adjacent to graphitic N on 1D carbon and the active site of HER is the pyridinic N on 1D *** presence of pyridinic N and pyrrolic N reduces the number of electron transfer,decreasing the reaction kinetics and the activity of CO_(2)*** CO/H_(2)ratio is related to the distribution of N species and the specific surface area,which are determined by the degree of spatial confinement *** CO/H_(2)ratios can be regulated by adjusting the carbonization temperature to adjust the degree of spatial confinement *** the low cost of feedstock and easy strategy,1D/3D NPC catalysts have great potential for industrial application.

关键词： electrochemical CO_(2)reduction reaction melamine sponge metal‐organic frameworks porous carbon syngas

Reasonable design a high-entropy garnet-type solid electrolyte for all-solid-state lithium batteries

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Journal of Energy Chemistry 2024年第9期96卷 414-423页

作者： Shiyu Yu Yandi Li Jiaxin Luo daming Chen Liang Yang Yaqing wei De Li Yuanxun Li Yong Chen State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science and EngineeringHainan Provincial Key Laboratory of Research on Utilization of Si-Zr-Ti ResourcesHainan UniversityHaikou 570228HainanChina State Key Laboratory of Electronic Thin Films1nd Integrated Devices University of Electronic Science and Technology of ChinaChengdu 610054SichuanChina Guangdong Key Laboratory for Hydrogen Energy Technologies School of Materials Science and Hydrogen EnergyFoshan UniversityFoshan 528000GuangdongChina

Traditional garnet solid electrolyte(Li_(7)La_(3)Zr_(2)O_(12))suffers from low room temperature ionic conductivity,poor air stability,high sintering temperature and energy *** the development prospects of high-entropy materials with high structural disorder and strong component controllability in the field of electrochemical energy storage,herein,a novel high-entropy garnet-type oxide solid electrolyte,Li_(5.75)Ga_(0.25)La_(3)Zr_(0.5)Ti_(0.5)Sn_(0.5)Nb_(0.5)O_(12)(LGLZTSNO)was constructed by partially replacing the Li and Zr sites in Li_(7)La_(3)Zr_(2)O_(12)with Ga and Ti/Sn/Nb elements,*** experimental and density functional theory(DFT)calculation results show that the high-entropy LGLZTSNO electrolyte has preferable room temperature ion conductivity,air stability,interface contact performance with lithium anode,and the ability to suppress lithium *** to the improvement of electrolyte performance,the critical current density of Li/Ag@LGLZTSNO/Li symmetric cell was increased from 0.42 to 1.57 mA cm^(−2),and the interface area specific impedance(IASR)was reduced from 765.2 to 42.3Ωcm^(2).Meanwhile,the Li/Ag@LGLZTSNO/LFP full cell also exhibits excellent rate performance and cycling performance(148 mA h g^(−1)at 0.1 C and 124 mA h g^(−1)at 0.5 C,capacity retention up to 84.8%after 100 cycles at 0.1 C),showing the application prospects of high-entropy LGLZTSNO solid electrolyte in high-performance all solid state lithium batteries.

关键词： Garnet solid electrolyte Dual-site substitution High-entropy all solid-state lithium batteries(ASSLBs)

Circular RNA circ_0003609 ameliorates hypertrophied ligamentum flavum by regulating the miR-155/SIRT1 axis

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BIOCELL 2024年第6期48卷 1001-1008页

作者： GUIBIN ZHONG SHURONG WANG YUJIN HE daming FENG KE wei YANQIU YANG JIANwei CHEN JUNLING CHEN Department of Orthopaedics Baoshan BranchRen Ji HospitalSchool of Medicine Shanghai Jiao Tong UniversityShanghai200444China Department of Orthopaedics Ren Ji HospitalSchool of Medicine Shanghai Jiao Tong UniversityShanghai200127China Department of Operation and Anaesthesia Ren Ji HospitalSchool of Medicine Shanghai Jiao Tong UniversityShanghai200127China Department of Orthopaedics Huai Yuan Chang Jiu HospitalHuaiyuan233499China

Background:Hypertrophy of the ligamentumﬂavum(HLF)is a common contributor to spinal stenosis which results in signiﬁcant neurological *** RNA(circRNA)circ_0003609 has been linked to HLF;however,the exact mechanism by which it causes this disease is ***:Circ_0003609 expressions were regulated in HLF cells by overexpression vectors and RNA *** proliferation andﬁbrosis-related gene expression were checked by the Cell Counting Kit-8(CCK-8)assay and western ***’s prediction of the association between miR-155 and circ_0003609 was supported by a dual-luciferase reporter *** function of the miR-155/sirtuin 1(SIRT1)axis in controlling HLFﬁbrosis was further ***:Overexpression of circ_0003609 suppressed HLF cell propagation andﬁbrosis compared to its *** was found that circ_0003609 served as the sponge for miR-155 and that the circ_0003609/miR-155 axis controlled theﬁbrosis of HLF *** was found that circ_0003609 acted as a sponge for miR-155,regulating theﬁbrosis of HLF ***,miR-155 targets SIRT1,and the miR-155/SIRT1 axis promotes HLF cellﬁ***:Circ_0003609 ameliorates hypertrophied ligamentumﬂavum(LF)by modulating the miR-155/SIRT1 axis,indicating a potential treatment approach for HLF.

关键词： Circular RNA Circ_0003609 Hypertrophy of ligamentum flavum MiR-155 Sirtuin 1 Fibrosis

基于全国耕地消纳的畜禽粪便特征分布与环境承载力预警分析

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中国生态农业学报（中英文） 2020年第5期28卷 745-755页

作者：张藤丽焉莉韦大明吉林农业大学资源与环境学院长春130118 生态环境部环境规划院总量控制与排放交易研究中心北京100012

为加快畜禽养殖行业粪污资源化利用,促进畜牧业可持续发展,及时掌握畜禽粪便的特征分布,对有效防控养殖区域环境的污染尤为重要。目前多数畜禽粪便污染研究都是基于省市区域尺度,而进行全国尺度的研究相对较少。本文运用排污系数法,以... 详细信息

为加快畜禽养殖行业粪污资源化利用,促进畜牧业可持续发展,及时掌握畜禽粪便的特征分布,对有效防控养殖区域环境的污染尤为重要。目前多数畜禽粪便污染研究都是基于省市区域尺度,而进行全国尺度的研究相对较少。本文运用排污系数法,以中国畜牧年鉴数据为计算基础,估算出2016年全国31个省份畜禽粪便的产生量、污染物产生量及污染物流失量。在此基础上,分析全国2016年畜禽粪便的排放分布特征,并将不同畜种的粪尿产生量统一换算为猪粪当量,计算出单位耕地面积猪粪当量承载负荷及预警值,参照相关标准得到2016年全国各省所对应的预警级别。结果表明:2016年全国畜禽粪便总产生量为246836万t,其中牛粪产量最多,家禽粪产生量最少;所研究的31个省份中四川省、河南省、山东省的粪便产生量较多。假设产生的粪便可以利用当年的有效耕地消纳,则2016年31个省份畜禽粪便平均单位耕地面积猪粪当量承载力负荷为19.55,单位耕地面积猪粪当量预警均值为0.49。本文所测算的31个省份中大部分省份预警值处于无环境威胁预警级别(Ⅰ级),但北京市处于有环境威胁预警级别(Ⅲ级),西藏自治区处于很严重环境威胁预警级别(Ⅵ级),青海处于严重环境威胁预警级别(Ⅴ级)。根据计算得出的预警级别,各省应根据自身情况充分利用畜禽粪便资源,尤其是在预警值较高地区应及时做好畜禽养殖总量控制及污染防控。

关键词：畜禽粪污猪粪当量排污系数法耕地负荷负荷预警

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不同造水工艺参数对产水品质的影响研究

核动力工程 2018年第S2期39卷 135-137页

作者：杨松唐远辉雷超魏大明陈庆旭中国核动力研究设计院成都610213

反应堆对造水系统产水品质有严格的要求,而产水pH值和电导率是反映产水品质的重要指标。基于反应堆现有造水工艺,通过改变工造水艺参数来控制进水pH值,研究不同造水工艺参数对产水pH值及电导率的影响,由此分析并提出产水品质最优的工艺... 详细信息

反应堆对造水系统产水品质有严格的要求,而产水pH值和电导率是反映产水品质的重要指标。基于反应堆现有造水工艺,通过改变工造水艺参数来控制进水pH值,研究不同造水工艺参数对产水pH值及电导率的影响,由此分析并提出产水品质最优的工艺参数,有效保障了反应堆用水品质需求。

关键词：工艺参数电导率 pH值

基于结构分解技术的内蒙古自治区规模化畜禽养殖业减排机制研究

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环境污染与防治 2016年第5期38卷 105-109页

作者：韦大明刘雅玲陈岩环境保护部环境规划院北京100012

运用结构分解技术(SDA),构建了内蒙古自治区规模化畜禽养殖业减排机制分析模型,将规模化畜禽养殖业COD和氨氮减排分解为规模效应、结构效应和技术效应,并根据模型测算了2011—2013年各种效应的数值。测算结果表明:COD和氨氮减排总效应... 详细信息

运用结构分解技术(SDA),构建了内蒙古自治区规模化畜禽养殖业减排机制分析模型,将规模化畜禽养殖业COD和氨氮减排分解为规模效应、结构效应和技术效应,并根据模型测算了2011—2013年各种效应的数值。测算结果表明:COD和氨氮减排总效应分别为50.95%和63.41%,畜禽养殖污染排放增长趋势仍未改变;规模效应分别为77.10%和79.96%,即养殖规模扩张增加COD和氨氮的排放;结构效应分别为-0.51%和7.53%,说明养殖结构调整对COD减排有利,但未促进氨氮减排;技术效应分别为-25.64%和-24.08%,是COD和氨氮减排的主要驱动力;从养殖种类看,生猪、奶牛养殖技术减排是影响整体技术效应的关键,肉鸡养殖的污染物去除率有所降低,需要推动减排工程并加强监管。

关键词：结构分解技术规模化畜禽养殖业减排机制