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Physiological and cognitive discontinuities:From mythical mediation to implicit discretization of architectural design tools

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Frontiers of Architectural Research 2023年第1期12卷 1-14页

作者： damien Claeys Louvain Research Institute for Landscape ArchitectureBuilt Environment(LAB)and Faculty of ArchitectureArchitectural Engineering and Urban Planning(LOCI)Universite´catholique de Louvain(UCLouvain)BrusselsBelgium

In architectural design,representation tools are often compared according to their alleged effects on the creativity of ***,their mediating capacities are often mythicized,to such an extent that one might surmise the direct transmission of the mental images from the designer’s consciousness to an external *** this speculative essay,we demonstrate that the process of representation at work in architectural design originates from the designer’s consciousness natural cognitive ability,rather than from the use of a specific mediation tool between the designer and his environment,between the mentally constructed architectural project and its *** effects of any tool of representationdanalog or digitaldon our perceptual apparatus depend primarily on the cognitive mechanisms affecting the discontinuous flow of internal representations formed by our *** other words,we propose to shed a new light on these limitations through the heuristic modeling of an architectural project designer confronted with his own cognitive biases,and the limits of the representation *** the present essay,the discontinuities and uncertainties inherent to the processes of representation are reintegrate in the models.

关键词： Architecture Design Representation Discretization Discontinuity Digital Analog Uncertainty

Factors Associated with High Blood Pressure and Diabetes Cormobidity in Littoral Department of Benin, in 2023

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Open Journal of Internal Medicine 2024年第2期14卷 188-212页

作者： Rodrigue Sèmèvo Kakpo Zannou Georgia Barikissou damien Léopold Codjo Coovi Nonwanou Ignace Tokpanoude Elvire Sègnon Eurydice Djossou Folabi Femi Teddy Attonde Lorens Sènan Zinsalo Mondoukpe Mouinatou Tao Marius Esse Badirou Aguemon Public Health Unit Faculty of Health Sciences University of Abomey-Calavi (UAC) Cotonou Bnin Cardiology Service National Hospital and University Center Hubert Koutoukou Maga de Cotonou (CNHU-HKM) University of Abomey-Calavi (UAC) Cotonou Bnin

Introduction: The number of people suffering from diabetes and hypertension (HBP) is increasing worldwide and particularly in sub-Saharan Africa, despite the fact that they are preventable. The aim of our study is to determine the factors associated with hypertension and diabetes comorbidity in the Department of Littoral in 2023. Study Setting and Methods: Our study took place in the Department of Littoral in Benin. It was a cross-sectional general population study conducted over a three-month period from April 10 to July 10, 2023. It included subjects aged 18 and over with or without a history of hypertension and/or diabetes. The sampling method was probabilistic and the technique used was a WHO three-stage cluster survey. The dependent variable is comorbidity of hypertension and diabetes. A logistic regression model was used to identify factors associated with hypertension-diabetes comorbidity. Results: The study population was predominantly female (59.9%). The mean age was 44 ± 17. A total of 48 (8.8%) of the subjects in the study suffered from both diabetes and hypertension. Factors associated with comorbidity of hypertension and diabetes were age ≥ 50 years (OR: 5.48;95% CI: 2.69 - 12.20;p = 0.001);male sex (OR: 2.98;95% CI: 1.39 - 6.46;p = 0.005);too much salt or salty sauce consumed (OR: 6.06;95% CI: 1.56 - 22.20;p = 0.034);abdominal obesity (OR: 6.12;95% CI: 2.79 - 14.3;p = 0.001). Conclusion: Hypertension and diabetes are emerging as major public health problems in Benin. The main associated factors were age, gender, the amount of salt or salty sauce consumed and abdominal obesity. A response is urgently needed to act on the factors identified in order to avoid possible complications and an increase in prevalence.

关键词： Comorbidity Hypertension-Diabetes Associated Factors Littoral Department Benin

Carbamylated lipoproteins in diabetes

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World Journal of Diabetes 2023年第3期14卷 159-169页

作者： damien Denimal Department of Biochemistry University Hospital of DijonDijon 21079France INSERM LNC UMR1231 University of BurgundyDijon 21078France

Diabetic dyslipidemia is characterized by quantitative and qualitative abnormalities in *** addition to glycation and oxidation,carbamylation is also a post-translational modification affecting lipoproteins in *** with type 2 diabetes(T2D)exhibit higher levels of carbamylated low-density lipoproteins(cLDL)and high-density lipoproteins(cHDL).Accumulating evidence suggests that cLDL plays a role in atherosclerosis in *** levels have been shown to predict cardiovascular events and all-cause *** facilitates immune cell recruitment in the vascular wall,promotes accumulation of lipids in macrophages,and contributes to endothelial dysf-unction,endothelial nitric oxide-synthase(eNOS)inactivation and endothelial repair ***,cLDL induces thrombus formation and platelet *** the other hand,recent data have demonstrated that cHDL serum level is independently associated with all-cause and cardiovascular-related mortality in T2D *** relationship may be causative since the atheroprotective properties of HDL are altered after ***,cHDL loses the ability to remove cholesterol from macrophages,to inhibit monocyte adhesion and recruitment,to induce eNOS activation and to inhibit *** together,it seems very likely that the abnormalities in the biological functions of LDL and HDL after carbamylation contribute to atherosclerosis and to the elevated cardiovascular risk in diabetes.

关键词： Carbamylation Lipoprotein Diabetes Low-density lipoprotein High-density lipoprotein Myeloperoxidase

Gym-ANM: Reinforcement learning environments for active network management tasks in electricity distribution systems

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能源与人工智能(英文) 2021年第3期5卷 171-193页

作者： Robin Henry damien Ernst School of Engineering Sanderson BuildingThe University of EdinburghEdinburgh EH93FBUK Department of Electrical Engineering and Computer Science Montefiore InstituteUniversity of LiegeLiege B-4000Belgium

Active network management(ANM)of electricity distribution networks include many complex stochastic sequential optimization *** problems need to be solved for integrating renewable energies and distributed storage into future electrical *** this work,we introduce Gym-ANM,a framework for designing reinforcement learning(RL)environments that model ANM tasks in electricity distribution *** environments provide new playgrounds for RL research in the management of electricity networks that do not require an extensive knowledge of the underlying dynamics of such *** with this work,we are releasing an implementation of an introductory toy-environment,ANM6-Easy,designed to emphasize common challenges in *** also show that state-of-the-art RL algorithms can already achieve good performance on ANM6-Easy when compared against a model predictive control(MPC)***,we provide guidelines to create new Gym-ANM environments differing in terms of(a)the distribution network topology and param-eters,(b)the observation space,(c)the modeling of the stochastic processes present in the system,and(d)a set of hyperparameters influencing the reward ***-ANM can be downloaded at https://***/robinhenr y/gym-anm.

关键词： Gym-ANM Reinforcement learning Active network management Distribution networks Renewable energy

Lock-in incoherent differential phase contrast imaging

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Photonics Research 2022年第1期10卷 237-247页

作者： CHIARA BONATI damien LOTERIE TIMOTHé LAFOREST CHRISTOPHE MOSER Laboratory of Applied Photonics Devices School of EngineeringEcole Polytechnique Fédérale de Lausanne1015 LausanneSwitzerland

We introduce a lock-in method to increase the phase contrast in incoherent differential phase contrast(DPC)*** method improves the phase sensitivity by the analog removal of the *** use of a smart pixel detector with in-pixel signal demodulation,paired with synchronized switching illumination,provides the basis of a bit-efficient approach to emulate a lock-in *** experiments show an increased sensitivity by a factor of up to 8,as expected from theory,and a reduction of collected data by a factor of 70,for equivalent standard DPC measurements;single-shot sensitivity of 0.7 mrad at a frame rate of 1400 frames per second is *** new approach may open the way for the use of incoherent phase microscopy in biological applications where extreme phase sensitivity and millisecond response time are required.

关键词： phase illumination differential

Dismantling Melaspileaceae:a first phylogenetic study of Buelliella,Hemigrapha,Karschia,Labrocarpon and Melaspilea

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Fungal Diversity 2015年第2期71卷 141-164页

作者： damien Ertz Paul Diederich Department Bryophytes-Thallophytes(BT) Botanic Garden MeiseNieuwelaan 38B–1860 MeiseBelgium Musée national d’histoire naturelle 25 rue MunsterL–2160 LuxembourgLuxembourg

Melaspileaceae is a heterogeneous group of Ascomycota including lichenized,lichenicolous and saprobic fungi.A first phylogenetic study of Melaspileaceae is presented and is based on mtSSU and nuLSU sequence *** obtained 49 new sequences for 28 specimens representing 15 *** genera Buelliella,Hemigrapha,Karschia,Labrocarpon and Melaspilea *** included in a molecular phylogeny for the first *** is recovered as polyphyletic,with members placed in two main lineages of *** *** included in *** is placed in synonymy with *** genus Encephalographa is placed in *** genera Buelliella,Karschia,Labrocarpon and several members of Melaspilea are demonstrated to belong to Asterinales,while Hemigrapha is confirmed in this *** genera Melaspileella,Melaspileopsis,Stictographa are reinstated for former Melaspilea species now placed in *** cezannei is described as new,and the new combinations Melaspilea costaricensis,***,***,Melaspileella proximella and Melaspileopsis diplasiospora are *** as newly defined includes lichenized and saprobic *** lichenicolous and saprobic life styles form different intermixed lineages in Asterinales that do not include lichenized *** phylogenetic data provide a first framework for dismantling further the genus Melaspilea for which most of the species are expected to belong to Asterinales.

关键词： Asterinales Eremithallales Lichenicolous fungi Phylogeny Taxonomy

Benefits of heterospecific aggregation on necromass: in fluence of temperature, group density, and compositi on on fitness-related traits

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Insect Science 2021年第1期28卷 144-152页

作者： Larissa Komo Valery Hedouin damien Charabidze CHU Lille EA 7367—UTML—Unite de Taphonomie Medico-LegaleUniversity of Lille59000 LilleFrance

Necrophagous blowflies(Diptera:Calliphoridae)such as Calliphora vicina,a cold-tolerant species,and L ucilia serie ata,a warm-adapted species,are pioneer carrion・*** these two species have different temperature preferences,larvae aggregate actively and often feed simultaneously on *** hypothesis to be tested was that *** benefits from the association with *** at lower temperatures(i.e.,15℃)and that *** derives greater benefits from this association at higher temperatures(i.e.,28℃).Therefore,both species were raised at these two constant temperatures from first instars to adults under three different conditions:monospecific low-density,monospecific high-density,and heterospecific *** time until larval migration,surface area of puparia,and survival rates were determined for each *** between these fitness-related traits were found between species,temperatures,group densities,and species *** 28°C,*** larvae bred in heterospecific groups migrated significantly earlier and in higher numbers than that under same density conspecific con・ditions,with a lower mortality *** 15°C,both species benefited from high-density heterospecific associations,expressed by faster development and larger *** conclusion,necrophagous larvae benefited from heterospecific aggregations at suboptima 1 temperatures by adapting their migration time to that of the faster *** temperature changes throughout the day and over the year,the beneficiary of such a collective association also *** costs involved and deviations to the temperature-size rule highlight the complexity of the carrion ecosystem.

关键词： carrion ecology development rhythm flies forensic entomology lifehistory traits mutualism

Neuronal and endothelial transglutaminase-2 expression in experimental autoimmune encephalomyelitis and multiple sclerosis

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Neural Regeneration Research 2022年第7期17卷 1471-1472页

作者： damien D.Pearse Mousumi Ghosh Miami Project to Cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Department of Neurological Surgery University of Miami Miller School of MedicineMiamiFLUSA Neuroscience Program Interdisciplinary Stem Cell InstituteUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Veterans Affairs Veterans Affairs Medical CenterMiamiFLUSA

Multiple sclerosis(MS)is a neurological condition characterized by the disruption of the blood-brain barrier,immune system activation,and infla mmation that is accompanied by glial reactivity,neuronal cell death,axon demyelination,and *** changes result in functional loss including paralysis,migraine,vision problems,spasticity,and neuropathic pain.

关键词： sclerosis paralysis autoimmune

Sediment bed destabilization by an isolated vortex:an experimental approach

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Journal of Hydrodynamics 2021年第2期33卷 370-385页

作者： Yann Devaux Lionel Thomas damien Calluaud Gérard Pineau Institut Pprime CNRS-Universitéde Poitiers-ISAE-ENSMA-UPR 3346PoitiersFrance

The destabilization of an erodible sediment bed by a reproducible impulsive phenomenon is studied *** this,a specific setup is designed to produce a well-controlled isolated vortex,advected over a uniform sand *** image velocimetry(PIV)measurements are performed to get fluid flow information;suspended particles images are also recorded.A new measurement technique,based on a stereo-correlation method,provides a precise reconstruction of the bedform morphology over *** turbulent structures(namely sweep events)are evidenced in a near-wall region,where particles are mainly *** sediment plume follows the vortex:in particular,the upward velocity inside maintains the suspension ***,the dispersion process seems to be not dependent on the vortex ***,the bed morphology is investigated:a scour hole is dug as the vortex hits the granular *** dynamics is described by a typical scour law,even if the initial perturbation is *** area,where the particles settled,can be observed:it behaves like a ripple,with a logarithmic growth of its *** deposition region has a specific geometry,studied here by a Fourier contour ***,a pickup rate is also derived from the morphological data:it appears independent of the vortex and bedform features.

关键词： Sediment plume isolated vortex stereo-correlation particle image velocimetry(PIV) bedform dynamics