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A dual-beam piezo-magneto-elastic wake-induced vibration energy harvesting system for high-performance wind energy harvesting

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Science China(Technological Sciences) 2024年第1期67卷 221-239页

作者： MA XiaoQing ZHANg Hang MARgIELEWICZ Jerzy gĄSKA damian WOLSZCZAK Piotr LITAK grzegorz ZHOU ShengXi School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China Research&Development Institute in Shenzhen Northwestern Polytechnical UniversityShenzhen 518057China Faculty of Transport and Aviation Engineering Silesian University of TechnologyKrasińskiego 8Katowice 40-019Poland Department of Automation Lublin University of TechnologyNadbystrzycka 36Lublin 20-618Poland

Wind-induced vibration energy harvesting has a great potential for utilizing wind energy to supply power for low-powered *** improve the working performance of energy harvesters effectively,a suitable structural design is *** paper proposes a dual-beam piezo-magneto-elastic wake-induced vibration energy harvesting system to enhance the functional performance of aeroelastic energy harvesters in environments with variable wind *** system contains two piezoelectric beams coupled by magnets(forming upstream and downstream energy harvesters),and each beam is attached with a foam cylinder.A corresponding dynamic model is provided,and output characteristics are obtained at different wind *** and experimental verification indicate that both upstream and downstream energy harvesters can realize efficient energy *** the wind speed exceeds a certain critical value,the amplitudes of the system’s displacement and voltage are *** wind speed threshold value is approximately 1.25 m/*** the wind speed and magnet spacing are 10.2 m/s and 20 mm,respectively,the output power of the system reaches 4.9×10^(−4)***,the wind speed threshold value of the proposed system can be adjusted by an equivalent nonlinear restoring force.

关键词： dual-beam structure piezoelectric energy harvester theoretical model nonlinear dynamics

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Modifying the progression of Parkinson's disease through movement interventions:multimodal quantification of underlying mechanisms

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Neural Regeneration Research 2024年第8期19卷 1651-1652页

作者： Manuel Bange damian Marc Herz Dumitru Ciolac gabriel gonzalez-Escamilla Sergiu groppa Section of Movement Disorders and Neurostimulation Department of NeurologyFocus Program Translational Neuroscience(FTN)University Medical Center of the Johannes Gutenberg-University MainzMainzGermany

Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement *** pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structu re and function of distributed brain *** r,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).

关键词： alterations movement

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High Strain-Rate and Shock Response of Carbon SupercompositeTM

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Open Journal of Composite Materials 2024年第3期14卷 132-145页

作者： Suman Babu Ukyam Raju P. Mantena damian L. Stoddard Arunachalam M. Rajendran Department of Mechanical Engineering University of Mississippi Mississippi USA

This study focuses on assessing the dynamic behaviors of carbon SupercompositeTM laminates when subjected to high strain-rates and air blast loads, using a shock tube for testing. The investigation aims to understand the response of these advanced materials under extreme conditions, which is crucial for applications in aerospace, military, and other high-performance industries. SupercompositeTM (CZE) prepreg, made up of a 3K plain weave carbon fabric with milled carbon fibers as interlaminar reinforcements impregnated with epoxy, is used to create SupercompositeTM (CZE) laminates. A woven carbon composite (CBE) laminate was also created using 3K plain weave Carbon/Epoxy (CBE) prepreg. Both types of laminates were designed and fabricated using the autoclave process. The dynamic behaviors of CZE and CBE laminate under transverse compression loads were evaluated using a modified Split Hopkinson Pressure Bar (SHPB). The study found that the 3D reinforcement with milled carbon fibers significantly affected the dynamic behavior of the CZE laminate. Stereo imaging videos, captured using two SHIMADZU high-speed video cameras in shock tube experiments, recorded the time history of back surface deflection. The plate specimens exhibited low deflections without any visible damage. The experimentally observed center point deflections of the CZE plates decayed sooner than those of the CBE laminates, indicating an improvement in damping due to the presence of 3D reinforced milled carbon fibers. This research shows that optimized utilization of milled carbon fibers as 3D reinforcement can withstand high stress in the thickness direction and higher energy absorption when subjected to impact and high strain-rate loading.

关键词： SupercompositeTM gOM Software 3D Reinforcement Milled Carbon Fibers Split Hopkinson Pressure Bar (SHPB) Air-Blast Loads

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An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs

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Bio-Design and Manufacturing 2024年第3期7卷 240-261页

作者： Seol-Ha Jeong Jarno Hiemstra Patrick V.Blokzijl Rebeca damian-Ferrara Danilo Martins dos Santos Jéssica H.L.da Fonseca Min-Ho Kang Jihyun Kim Dilara Yilmaz-Aykut Mei L.L.Cham-Pérez Jeroen Leijten Su Ryon Shin Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA Leijten Lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nanotechnology National Laboratory for Agriculture(LNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Department of Biomedical-Chemical Engineering The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Department of Biotechnology The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural *** in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted *** oxygen-releasing biomaterials,such as oxygen-generating microparticles(OMPs),have shown promise for enhancing the oxygen supply of microenvironments in injured tissues,whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain *** study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine colloidal-based microgels with *** report that incorporating nanosized calcium peroxide(nCaO_(2))and manganese oxide nanosheets(nMnO_(2))into hydrophobic polymeric microparticles enables precise modulation of oxygen release while controlling hydrogen peroxide ***,the fabrication of oxygenating and cytocompatible colloidal gels is achieved using an aqueous two-phase *** study thoroughly evaluates the fundamental characteristics of the resulting bioink,including its rheological behaviors,printability,shape fidelity,mechanical properties,and oxygen release ***,this study demonstrates the macroscopic scalability and cytocompatibility of printed constructs produced via cell-laden oxygenating colloidal *** showcasing the effectiveness of extrusion-based bioprinting,this study underscores how it can be used to fabricate biomimetic tissues,indicating its potential for new *** findings presented here advance the bioprinting field by achieving scalability with both high cell viability and the possibility of mimicking specifically oxygenated *** work thereby offers a promising avenue for the development of functional tissues with e

关键词： 3D bioprinting Bioink Colloidal gels Extrusion printing Oxygen-generating microparticle

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Britanin–a beacon of hope against gastrointestinal tumors?

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World Journal of Clinical Oncology 2024年第4期15卷 523-530页

作者： Agnieszka Kajdanek damian Kołat Lin-Yong Zhao Mateusz Kciuk Zbigniew Pasieka Żaneta Kałuzińska-Kołat Department of Biomedicine and Experimental Surgery Medical University of LodzLodz 90-136LodzkiePoland Department of Functional genomics Medical University of LodzLodz 90-752LodzkiePoland Department of general Surgery&Laboratory of gastric Cancer State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina gastric Cancer Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Molecular Biotechnology and genetics University of LodzLodz 90-237LodzkiePoland

Britanin is a bioactive sesquiterpene lactone known for its potent anti-inflammatory and anti-oxidant *** also exhibits significant anti-tumor activity,suppressing tumor growth in vitro and in *** current body of research on Britanin includes thirty papers predominantly related to neoplasms,the majority of which are gastrointestinal tumors that have not been summarized *** drive academic debate,the present paper reviews the available research on Britanin in gastrointestinal *** also outlines novel research directions using data not directly concerned with the digestive system,but which could be adopted in future gastrointestinal *** was found to counteract liver,colorectal,pancreatic,and gastric tumors,by regulating proliferation,apoptosis,autophagy,immune response,migration,and *** confirmed in pancreatic,gastric,and liver cancer,its most commonly noted molecular effects include nuclear factor kappa B and B-cell lymphoma 2 downregulation,as well as Bcl-2-associated X protein ***,it has been found to induce the Akt kinase and Forkhead box O1 axis,activate the AMP-activated protein kinase pathway,elevate interleukin-2 and peroxisome proliferator-activated receptor-γlevels,reduce interleukin-10,as well as downregulate matrix metalloproteinase-9,Twist family bHLH transcription factor 1,and *** also inhibits Myc–HIF1αinteraction and programmed death ligand 1 transcription by interrupting the Ras/RAF/MEK/ERK pathway and mTOR/P70S6K/4EBP1 *** research should aim to unravel the link between Britanin and acetylcholinesterase,mast cells,osteolysis,and ischemia,as compelling data have been provided by studies outside the gastrointestinal *** the cytotoxicity of Britanin on noncancerous cells is significantly lower than that on tumor cells,while still being effective against the latter,further in-depth studies with the use of animal models are *** compound exhi

关键词： Britanin Sesquiterpene lactones Chemotherapeutics gastrointestinal tumors In vitro In vivo

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Revisiting the standards of cancer detection and therapy alongside their comparison to modern methods

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World Journal of Methodology 2024年第2期14卷 17-37页

作者： Piotr gromek Zuzanna Senkowska Elzbieta Pluciennik Zbigniew Pasieka Lin-Yong Zhao Adrianna gielecinska Mateusz Kciuk Karol Klosinski Zaneta Kaluzinska-Kolat damian Kolat Department of Functional genomics Medical University of LodzLodz 90-752LodzkiePoland Department of Biomedicine and Experimental Surgery Medical University of LodzLodz 90-136LodzkiePoland Department of general Surgery&Laboratory of gastric Cancer State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina gastric Cancer Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Molecular Biotechnology and genetics University of LodzLodz 90-237LodzkiePoland Doctoral School of Exact and Natural Sciences University of LodzLodz 90-237LodzkiePoland

In accordance with the World Health Organization data,cancer remains at the forefront of fatal *** upward trend in cancer incidence and mortality has been observed globally,emphasizing that efforts in developing detection and treatment methods should *** diagnostic path typically begins with learning the medical history of a patient;this is followed by basic blood tests and imaging tests to indicate where cancer may be located to schedule a needle *** initiation of diagnosis is crucial since delayed cancer detection entails higher costs of treatment and ***,there is a need for novel cancer detection methods such as liquid biopsy,elastography,synthetic biosensors,fluorescence imaging,and reflectance confocal *** therapeutic methods,although still common in clinical practice,pose many limitations and are ***,there is a dynamic advancement of clinical research and the development of more precise and effective methods such as oncolytic virotherapy,exosome-based therapy,nanotechnology,dendritic cells,chimeric antigen receptors,immune checkpoint inhibitors,natural product-based therapy,tumor-treating fields,and photodynamic *** present paper compares available data on conventional and modern methods of cancer detection and therapy to facilitate an understanding of this rapidly advancing field and its future *** evidenced,modern methods are not without drawbacks;there is still a need to develop new detection strategies and therapeutic approaches to improve sensitivity,specificity,safety,and ***,an appropriate route has been taken,as confirmed by the approval of some modern methods by the Food and Drug Administration.

关键词： Cancer detection Liquid biopsy Synthetic biosensors Fluorescence imaging Reflectance confocal microscopy Elastography Cancer therapy Tumor-treating fields Oncolytic virotherapy Nanotechnology

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Stem cell therapy applied for digestive anastomosis: Current state and future perspectives

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World Journal of Stem Cells 2022年第1期14卷 117-141页

作者： Jacobo Trébol Tihomir georgiev-Hristov Isabel Pascual-Miguelañez Hector guadalajara Mariano garcía-Arranz damian garcía-olmo Servicio de Cirugía general y del Aparato Digestivo Complejo Asistencial Universitario de SalamancaSalamanca 37007Spain Departamento de Anatomía e Histología Humanas Universidad de SalamancaSalamanca 37007Spain Servicio de Cirugía general y del Aparato Digestivo Hospital General Universitario de VillalbaMadrid 28400Spain Servicio de Cirugía general y del Aparato Digestivo Hospital Universitario La PazMadrid 28046Spain Servicio de Cirugía general y del Aparato Digestivo Hospital Universitario Fundación Jiménez DíazMadrid 28040Spain grupo de Investigación en Nuevas Terapias Instituto de Investigación Sanitaria-Fundación Jiménez DíazMadrid 28040Spain damian garcía-olmo Departamento de CirugíaUniversidad Autónoma de MadridMadrid 28029Spain Servicio de Cirugía general y del Aparato Digestivo Hospital Universitario Fundación Jiménez Díaz y Grupo Quiron-Salud MadridMadrid 28040Spain

BACKgROUND Digestive tract resections are usually followed by an *** leakage,normally due to failed healing,is the most feared complication in digestive surgery because it is associated with high morbidity and *** technical and technological advances and focused research,its rates have remained almost unchanged the last *** the last two decades,stem cells(SCs)have been shown to enhance healing in animal and human studies;hence,SCs have emerged since 2008 as an alternative to improve anastomoses *** To summarise the published knowledge of SC utilisation as a preventative tool for hollow digestive viscera anastomotic or suture *** PubMed,Science Direct,Scopus and Cochrane searches were performed using the key words“anastomosis”,“colorectal/colonic anastomoses”,“anastomotic leak”,“stem cells”,“progenitor cells”,“cellular therapy”and“cell therapy”in order to identify relevant articles published in English and Spanish during the years of 2000 to *** employing SCs,performing digestive anastomoses in hollow viscera or digestive perforation sutures and monitoring healing were finally *** lists from the selected articles were reviewed to identify additional pertinent *** given the great variability in the study designs,anastomotic models,interventions(SCs,doses and vehicles)and outcome measures,performing a reliable meta-analysis was considered impossible,so we present the studies,their results and *** Eighteen preclinical studies and three review papers were identified;no clinical studies have been published and there are no registered clinical *** studies,mainly in rat and porcine models and occasionally in very adverse conditions such as ischaemia or colitis,have been demonstrated SCs as safe and have shown some encouraging morphological,functional and even clinical *** SCs are mostly employed,and delivery routes are mainly local

关键词： Surgical anastomosis Anastomotic leak Digestive system surgical procedure Cell transplantation Cell therapy Stem cells Tissue engineering

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Application of Machine Learning for Flood Prediction and Evaluation in Southern Nigeria

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Atmospheric and Climate Sciences 2024年第3期14卷 299-316页

作者： Emeka Bright Ogbuene Chukwumeuche Ambrose Eze Obianuju getrude Aloh Andrew Monday Oroke damian Onuora Udegbunam Josiah Chukwuemeka Ogbuka Fred Emeka Achoru Vivian Amarachi Ozorme Obianuju Anwara Ikechukwu Chukwunonyelum Anthonia Nneka Nebo Obiageli Jacinta Okolo Centre for Environmental Management and Control (CEMAC) University of Nigeria Enugu Nigeria Department of geography Enugu State University of Science and Technology ESUT Enugu Nigeria School of Civil Engineering Newcastle University Newcastle upon Tyne UK

This study explored the application of machine learning techniques for flood prediction and analysis in southern Nigeria. Machine learning is an artificial intelligence technique that uses computer-based instructions to analyze and transform data into useful information to enable systems to make predictions. Traditional methods of flood prediction and analysis often fall short of providing accurate and timely information for effective disaster management. More so, numerical forecasting of flood disasters in the 19th century is not very accurate due to its inability to simplify complex atmospheric dynamics into simple equations. Here, we used Machine learning (ML) techniques including Random Forest (RF), Logistic Regression (LR), Naïve Bayes (NB), Support Vector Machine (SVM), and Neural Networks (NN) to model the complex physical processes that cause floods. The dataset contains 59 cases with the goal feature “Event-Type”, including 39 cases of floods and 20 cases of flood/rainstorms. Based on comparison of assessment metrics from models created using historical records, the result shows that NB performed better than all other techniques, followed by RF. The developed model can be used to predict the frequency of flood incidents. The majority of flood scenarios demonstrate that the event poses a significant risk to people’s lives. Therefore, each of the emergency response elements requires adequate knowledge of the flood incidences, continuous early warning service and accurate prediction model. This study can expand knowledge and research on flood predictive modeling in vulnerable areas to inform effective and sustainable contingency planning, policy, and management actions on flood disaster incidents, especially in other technologically underdeveloped settings.

关键词： Machine Learning Flood Prediction Evaluation Southern Nigeria

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Autonomous atomic Hamiltonian construction and active sampling of X-ray absorption spectroscopy by adversarial Bayesian optimization

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npj Computational Materials 2023年第1期9卷 1890-1900页

作者： Yixuan Zhang Ruiwen Xie Teng Long damian günzing Heiko Wende Katharina J.Ollefs Hongbin Zhang Institute of Materials Science Technical University of Darmstadt64287 DarmstadtGermany School of Materials Science and Engineering Shandong University250061 JinanChina Faculty of Physics University of Duisburg-Essen47057 DuisburgGermany

X-ray absorption spectroscopy(XAS)is a well-established method for in-depth characterization of electronic *** practice hundreds of energy-points should be sampled during the measurements,and most of them are ***,it is also tedious to estimate reasonable parameters in the atomic Hamiltonians for mechanistic *** implement an Adversarial Bayesian optimization(ABO)algorithm comprising two coupled BOs to automatically fit the many-body model Hamiltonians and to sample effectively based on active learning(AL).Taking NiO as an example,we find that less than 30 sampling points are sufficient to recover the complete XAS with the corresponding crystal field and charge transfer models,which can be selected based on intuitive hypothesis *** applications on the experimental XAS spectra reveal that less than 80 sampling points give reasonable XAS and reliable atomic model *** ABO algorithm has a great potential for future applications on automated physics-driven XAS analysis and AL sampling.

关键词： structure Hamiltonian absorption

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Investigations on influence of rifle automatics system action on values of energetic efficiency coefficient of muzzle brakes

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Defence Technology（防务技术） 2022年第10期18卷 1741-1747页

作者： Radoslaw Trebinski Zbigniew Leciejewski Jacek Kijewski Dawid gozdzik damian Szupienko Military University of Technology Faculty of MechatronicsArmament and Aerospaceul.Gen.S.Kaliskiego 200-908WarszawaPoland

The objective of the paper was to compare values of the muzzle brake efficiency coefficient for a rifle with active or inactive automatics *** laboratory stand designed for investigating the recoil process was *** motion of the rifle was detected by the use of the laser interferometer and the optical *** recoil velocity time courses were determined by smoothing and differentiation of experimental position *** results of the experiments indicated that in the case of an active automatics system two values of the recoil velocity can be used for calculation of the energetic efficiency coefficient:the maximum recoil velocity and the final recoil velocity at the end of the automatics action *** values of the coefficient,calculated using these two values of the recoil velocity,distinctly ***,it was shown that their values indicate the same relation between the efficiency of various muzzle *** value of the efficiency coefficient,determined on the basis of the final recoil velocity value,is practically the same as that determined on the basis of the final recoil velocity value for the rifle with an inactive automatics system.

关键词： Ballistics Muzzle brakes Automatic rifle Efficiency Recoil velocity

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