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Predictive value of preoperative routine examination for the prognosis of patients with pT2N0m0 or pT3N0m0 colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2429-2438页

作者： Peng-Fei Jing Jin Chen en-Da Yu Chao-Yu miao Department of Colorectal Surgery Changhai HospitalSecond Military Medical University/Naval Medical UniversityShanghai 200433China Department of endocrinology and metabolism Changhai HospitalSecond Military Medical University/Naval Medical UniversityShanghai 200433China Department of Pharmacology Second Military Medical University/Naval Medical UniversityShanghai 200433China

BACKGROUND In recent years,the incidence of colorectal cancer(CRC)has been *** the popularization of endoscopic technology,a number of early CRC has been ***,despite current treatment methods,some patients with early CRC still experience postoperative recurrence and *** To search for indicators associated with early CRC recurrence and metastasis to identify high-risk *** A total of 513 patients with pT2N0m0 or pT3N0m0 CRC were retrospectively enrolled in this *** of blood routine test,liver and kidney function tests and tumor markers were collected before *** were followed up through disease-specific database and telephone *** recurrence,metastasis or death were used as the end point of study to find the risk factors and predictive value related to early CRC recurrence and *** We comprehensively compared the predictive value of preoperative blood routine,blood biochemistry and tumor markers for disease-free survival(DFS)and overall survival(OS)of *** multivariate analysis demonstrated that low platelet count was significantly associated with poor DFS[hazard ratio(HR)=0.995,95% confidence interval(CI):0.991-0.999,P=0.015],while serum carcinoembryonic antigen(CEA)level(HR=1.008,95%CI:1.001-1.016,P=0.027)and serum total cholesterol level(HR=1.538,95%CI:1.026-2.305,P=0.037)were independent risk factors for *** cutoff value of serum CEA level for predicting OS was 2.74 ng/*** the OS of CRC patients with serum CEA higher than the cutoff value was worse than those with lower CEA level,the difference between the two groups was not statistically significant(P=0.075).CONCLUSION For patients with T2N0m0 or T3N0m0 CRC,preoperative platelet count was a protective factor for DFS,while serum CEA level was an independent risk factor for *** that these measures are easier to detect and more acceptable to patients,they may have broader applications.

关键词： Colorectal cancer Platelet count Serum carcinoembryonic antigen Total cholesterol level Overall survival Disease-free survival

Stability and Generalization of Hypergraph Collaborative Networks

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machine Intelligence Research 2024年第1期21卷 184-196页

作者： michael K.ng Hanrui Wu Andy Yip Institute of Data Science The University of Hong KongHong KongChina Department of mathematics The University of Hong KongHong KongChina College of Information Science and Technology Jinan UniversityGuangzhou 510006China

Graph neural networks have been shown to be very effective in utilizing pairwise relationships across ***,there have been several successful proposals to generalize graph neural networks to hypergraph neural networks to exploit more com-plex *** particular,the hypergraph collaborative networks yield superior results compared to other hypergraph neural net-works for various semi-supervised learning *** collaborative network can provide high quality vertex embeddings and hyperedge embeddings together by formulating them as a joint optimization problem and by using their consistency in reconstructing the given *** this paper,we aim to establish the algorithmic stability of the core layer of the collaborative network and provide generaliz--ation *** analysis sheds light on the design of hypergraph filters in collaborative networks,for instance,how the data and hypergraph filters should be scaled to achieve uniform stability of the learning *** experimental results on real-world datasets are presented to illustrate the theory.

关键词： Hypergraphs vertices hyperedges collaborative networks graph convolutional neural networks(CNNs) stability generalization guarantees

High-Performance and Large-Area Inverted Perovskite Solar Cells Based on NiO_(x) Films enabled with A Novel microstructure-Control Technology

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energy & environmental materials 2024年第1期7卷 153-159页

作者： Guibin Shen Xin Li Yuqin Zou Hongye Dong Dongping Zhu Yanglin Jiang Xin Ren ng Fen Lin Peter müller-Buschbaum Cheng mu Key Laboratory of Advanced Light Conversion materials and Biophotonics Department of ChemistryRenmin University of ChinaBeijing 100872China Solar energy Research Institute of Singapore(SERIS) National University of SingaporeSingapore 117574Singapore Physik-Department Lehrstuhl für Funktionelle MaterialienTechnische Universität MünchenJames-Franck-Straße 185748Garching Germany Heinz maier-Leibnitz Zentrum(mLZ) Technische Universität MünchenLichtenbergstr.185748Garching Germany

The improvement in the efficiency of inverted perovskite solar cells(PSCs)is significantly limited by undesirable contact at the NiO_(x)/perovskite *** this study,a novel microstructure-control technology is proposed for fabrication of porous NiO_(x)films using Pluronic P123 as the structure-directing agent and acetylacetone(AcAc)as the coordination *** synthesized porous NiO_(x)films enhanced the hole extraction efficiency and reduced recombination defects at the NiO_(x)/perovskite ***,without any modification,the power conversion efficiency(PCE)of the PSC with mAPbl_(3)as the absorber layer improved from 16.50%to 19.08%.moreover,the PCE of the device composed of perovskite Cs0.05(mA_(0.15)FA_(0.85))_(0.95)Pb(I_(0.85)Br_(0.15))_(3)improved from 17.49%to 21.42%.Furthermore,the application of the fabricated porous NiO_(x)on fluorine-doped tin oxide(FTO)substrates enabled the fabrication of large-area PSCs(1.2 cm^(2))with a PCE of 19.63%.This study provides a novel strategy for improving the contact at the NiO_(x)/perovskite interface for the fabrication of high-performance large-area perovskite solar cells.

关键词： interfacial contact inverted and large-area perovskite solar cells photovoltaic materials porous NiO_(x)films renewable energy

Three-year field study on grass growth and soil hydrological properties in biochar-amended soil

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Journal of Rock mechanics and Geotechnical engineering 2024年第7期16卷 2764-2774页

作者： Haowen Guo Charles Wang Wai ng Junjun Ni Qi Zhang Yuchen Wang Department of Civil and environmental engineering The Hong Kong University of Science and TechnologyHong KongChina School of Transportation Southeast UniversityNanjingChina

Field monitoring was conducted to investigate and quantify the long-term effects of peanut shell biochar on soil-grass interaction over three *** 10 m5 m grassed plots were constructed in completely decomposed granitic *** of them were amended,respectively,with 5%and 10%biochar contents(m^(3)/m^(3))for grass growth,while the third was without biochar *** the threeyear monitoring,plant characteristics,saturated water permeability(k_(s))of grassed soil and soil suction were *** monitored results show that the grass leaf area index(LAI)and root length density(RLD)with biochar amendment were improved by 38%and 200%,*** the grassed plot without biochar,a threshold RLD existed with a value of 1.7 cm/cm^(3),beyond which k_(s) raised *** threshold RLD increased by 52%when biochar content increased from 0%to 10%.This implies that biochar may restrict the increase in k_(s) of grassed soil due to the rise in the threshold *** presence of biochar and grass can retain over 100%higher suction after heavy rainfalls,while 54%lower peak suction under evapotranspiration(ET)compared with the non-amended *** can alleviate the negative effects on hydraulic properties caused by plant growth and reduce ET-induced excessive water loss.A 5%peanut shell biochar content is recommended for the long-term management of vegetated earthen infrastructures.

关键词： Soil-grass interaction Biochar Long-term Water infiltration Soil drying

Exogenous testosterone therapy on choroid in androgen deficiency

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International Journal of Ophthalmology(english edition) 2024年第8期17卷 1489-1494页

作者： Volkan Yeter Nurullah Koçak merve Kalyoncu Ramazan Aşçi Nurşen Aritürk Department of Ophthalmology Ondokuz Mayıs UniversitySamsun 55139Turkey Department of Urology Ondokuz Mayıs UniversitySamsun 55139Turkey

AIm:To investigate the effects of exogenous testosterone treatment on the choroidal parameters in patients with androgen ***:Right eyes of 24 patients with androgen deficiency and 31 healthy volunteers were included in the *** eyes were scanned for subfoveal choroidal thickness(SFCT),choroidal vascularity index(CVI),choroidstromal area(C-SA),choroid-luminal area(C-LA),choroidstromal to luminal area ratio(CSLR),and the choroidal parameters within central 1500μm of the macula(CVI1500,C-LA1500,C-SA1500,and CSLR1500)by enhanced-depth imaging optical coherence tomography(EDI-OCT)at baseline,6th and 18th weeks of the exogenous testosterone ***:The mean SFCT values of the androgen deficient groups and healthy controls were 307.7±27.0 and 303.2±37.2μm(P=0.8).However,CVI,C-SA,CSLR,CVI1500,C-LA1500,and CSLR1500 were significantly different between the groups(all Penous testosterone treatment,SFCT,CVI,C-LA,and C-SA were significantly decreased,and these parameters returned to baseline levels at the 18th-week visit(all P>0.05).However,CVI1500 and LA1500 significantly increased at the end of the follow-up period(Pen-deficient patients than in healthy *** alterations in the choroid during the testosterone peak are transient in the treatment of patients with androgen ***,the increase in CVI within the central 1500μm of the macula persists even after 4mo.

关键词： testosterone androgen deficiency choroid vascularity index

Potential applications of single-incision laparoscopic totally preperitoneal hernioplasty

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2202-2210页

作者： Xiao-Jun Wang Ting Fei Xiong-Hua Xiang Quan Wang en-Cheng Zhou Department of Gastrointestinal Surgery The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina Ambulatory Surgery Center Xijing HospitalAir Force Military Medical UniversityXi’an 710032Shaanxi ProvinceChina

BACKGROUND The totally preperitoneal(TPP)approach is a new concept that was recently *** the TPP approach combined with single-incision laparoscopic hernia repair has its own advantages,there is little evidence reflecting the characteristics and feasibility of either *** To analyze the potential applications of single-incision laparoscopic TPP(SILTPP)inguinal hernia hernioplasty for the treatment of inguinal *** A total of 152 SIL-TPP surgeries were performed at the First Affiliated Hospital of Ningbo University from February 2019 to November 2022.A single-port,named Iconport,and standard laparoscopic instruments were used during the *** data,intraoperative parameters and short-term postoperative outcomes were collected and retrospectively *** The demographic data of 152 patients underwent SIL-TPP were shown in Table *** average age was 49.5 years(range from 21 to 81 years).The average body mass index was 27.7 kg/m^(2)(range from 17.7 kg/m^(2) to 35.6 kg/m^(2)).SIL-TPP were conducted successfully in 147 *** patients were converted to the SILtransabdominal preperitoneal laparoscopic herniorrhaphy at the initial stage of the study due to a lack of *** 2 patients with incisional hernias,an auxiliary operation hole was added during the SIL-TPP procedure,as required for *** mean operative time was 64.5 minutes(range:36.0-110.0 minutes)for unilateral direct and femoral hernias and 81.6 minutes for indirect hernias(range:40.0-150.0 minutes).The mean postoperative hospital stay was 3.4 *** SIL-TPP is feasible and has advantages for inguinal hernia ***-TPP has potential benefits for patients with various abdominal wall ***,doctors should be encouraged to actively apply the TPP approach combined with a single incision in their daily work.

关键词： Totally preperitoneal hernioplasty Iconport Single incision laparoscopic Totally extraperitoneal herniorrhaphy Single incision laparoscopic totally preperitoneal hernioplasty

Computational design of structured chemical products

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Frontiers of Chemical Science and engineering 2021年第5期15卷 1033-1049页

作者： Faheem mushtaq Xiang Zhang Ka Y.Fung Ka m.ng Department of Chemical and Biological engineering The Hong Kong University of Science and TechnologyHong KongChina

In chemical product design,the aim is to formulate a product with desired *** and internal product structure are two key drivers of product performance with direct impact on the mechanical,electrical,and thermal ***,there is a keen interest in elucidating the dependence of product performance on ingredients,structure,and the manufacturing process to form the *** of product structure,particularly microstructure,is an intrinsically complex problem that involves different phases of different physicochemical properties,mass fraction,morphology,size distribution,and ***,computational methods have emerged that assist systematic microstructure quantification and *** objective of this paper is to review these computational methods and to show how these methods as well as other developments in product design can work seamlessly in a proposed performance,ingredients,structure,and manufacturing process framework for the design of structured chemical *** begins with the desired target properties and key *** is followed by computation for microstructure and then selection of processing steps to realize this *** framework is illustrated with the design of nanodielectric and die attach adhesive products.

关键词： product design performance ingredients structure manufacturing process framework structured chemical products microstructure design

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宝鸡旭光m19及关中春秋早期戎狄遗存刍论

文博 2024年第3期 23-33,156页

作者：张天恩西北大学文化遗产学院陕西西安710127 陕西省考古研究院陕西西安710109

宝鸡旭光墓地石椁墓m19的葬俗和随葬品形制独特,是典型的戎狄文化墓葬在关中的首次亮相。其与夏家店上层文化的内蒙古宁城南山根石椁墓及出土文物具有相似性,可能早到春秋早期。结合韩城梁带村、澄城刘家洼芮国墓地出土的与戎狄文化相... 详细信息

宝鸡旭光墓地石椁墓m19的葬俗和随葬品形制独特,是典型的戎狄文化墓葬在关中的首次亮相。其与夏家店上层文化的内蒙古宁城南山根石椁墓及出土文物具有相似性,可能早到春秋早期。结合韩城梁带村、澄城刘家洼芮国墓地出土的与戎狄文化相关的金器、铜器,以及其他零星出土文物,可以对关中地区春秋早期或略晚的戎狄文化遗存的基本特征、分布状况、文化属性等有初步认识,进而了解此期戎狄人群、文化与中原周秦文化的交流、融合,及其在关中东周早期社会格局中的地位及影响。

关键词：春秋早期关中戎狄遗存

engineering Cumn Prussian blue analog-shelled nanobox for efficient electrochemical reduction of nitrate to ammonia

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Tungsten 2024年第4期6卷 833-844页

作者： Zi-Yi Yang Yu-Dong Li Dan Liu mao-Sen Song Yang Gao Qing-Ping Wu en-Shan Han Yan-Zhen He Xiao-Hui Yang School of Chemical engineering and Technology Hebei University of Technology Key Laboratory of Bio-Based material Science and Technology Northeast Forestry University Institute of Electrochemical energy Storage Helmholtz-Zentrum Berlin für Materialien und Energie Chongqing Institute of Green and Intelligent Technology Chinese Academy of Sciences

Electrocatalytic nitrate reduction reaction（enRR） for ammonia synthesis is a promising strategy to relieve nitration contamination,as well as an alternative to the Haber-Bosch *** blue analogs（PBAs） are expected to be an electrocatalytic material with superior performance owing to their abundant active sites and open channel ***,most reported PBA materials possess low nitrate conversion and ammonia yield rates,which has led to a hindrance in their research of ***,Cumn-PBA-shelled nanoboxes（Cumn-PBA SNBs） synthesized through tannic acid etching and cation exchange approaches are demonstrated for efficient ammonia *** optimal Cumn-PBA SNBs electrode achieves a high nitrate conversion of 91.33% and ammonia selectivity of 98.87% in a 0.2 mol·L-1Na2SO4solution with100×10-6NO3--N at-1.4 V ***,the Cumn-PBA SNB s electrode exhibits exceptional stability throughout a 30 h electrocatalytic *** outstanding electrochemical performance is attributed to the unique hollow nanobox structure with abundant active sites and high-throughput transport pathways for ions' aspects.

关键词： Acid etching Ammonia synthesis Cation exchange Electrocatalytic nitrate reduction Nanobox Prussian blue analogs