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The effect of ozone on pine forests in South-Eastern France from 2017 to 2019

Journal of Forestry Research 2023年第2期34卷 301-315页

作者： Anumol Shashikumar Svetlana Bičárová dalstein-richier laurence Groupe International d′Etudes Des Forêts Sud-Européennes(G.I.E.F.S) 69Avenue des Hespérides06300 NiceFrance Institute of Earth Science of the Slovak Academy of Sciences 05960 StaráLesnáTatranskáLomnicaSlovakia

In South-Eastern forests of France,risks linked to the effects of tropospheric ozone(O_(3))are real;its annual impact has been observed specifically near the coastline and in high altitude mountains during the period 2017-2019.In this study,the risk assessment of O_(3)pollutant was carried out using two approaches based on forest response indicators such as O_(3)specific foliar visible injury and by stomatal O_(3)flux.Phytotoxic O_(3)dose values(POD_(0))were obtained by the DO_(3)SE model.The model requires hourly O_(3)concentration for POD_(0)calculation.A modified approach that uses measurements from passive samplers(monthly average O_(3)concentration)was tested for the calculation of POD_(0)and test results showed good agreement with the POD_(0)calculated using hourly O_(3)data.In the model input file,the average O_(3)concentration is used for POD_(0),and this could be useful for POD_(0)calculation when the active monitor is limited.In this study,a flux-based assessment provided better correlation with O_(3)specific leaf injury,which is also species-specific.Foliar visible injury in response to O_(3)indicates that Pinus cembra and Pinus halepensis are more affected and therefore more sensitive than Pinus sylvestris.The POD_(0)and stomatal conductance(Gsto)seem to be induced by environmental factors,primarily rainfall and the soil water potential(fSWP).The correlation between the O_(3)flux metric and environmental variables with forest response indicators by Spearman rank test confirms P.cembra as one of the most sensitive species to O_(3).

关键词： Ozone Foliar visible injury Phytotoxic ozone dose Stomatal conductance DO_(3)SE

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Exploring the effects of anthropogenic disturbance on predator inspection activity in Trinidadian guppies

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Current Zoology 2024年第1期70卷 109-111页

作者： Alix J.P Brusseau laurence E.A.Feyten Adam L.Crane Grant E.Brown Department of Biology Concordia UniversityMontrealQCH4B 1R6Canada Department of Biomedical Sciences WCVMUniversity of SaskatchewanSaskatoonSKCanada

Prey animals are often faced with uncertainty due to having imperfect information regarding current local conditions,including predation risks and the availability of reliable foraging opportunities(Dall 2010).As this uncertainty increases,the probability of making costly behavioral errors also increases,leading to more risk averse behavioral tactics(Feyten et al.2019).For example,Trinidadian guppies Poecilia reticulata are far more risk averse when faced with multiple unknown sources of risk assessment information than when faced with a mix of known and unknown cues(Feyten et al.2019).Prey can reduce uncertainty by gathering and integrating private and social information regarding current risk levels within microhabitats(Dall 2010;Munoz and Blumstein 2012).

关键词： human disturbance information availability information reliability predator-prey interactions risk assessment uncertainty

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A Speculation: Avian Migration and the K-T Extinction

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Natural Resources 2024年第5期15卷 125-129页

作者： laurence Stephenson Association of Professional Engineers and Geologists of British Columbia Vancouver Canada

One caveat to the dinosaur’s extinction is the conclusion that avian dinosaurs survived and became ancestors of birds. Their mobility enabled them to migrate great distances and find the nutrients needed to survive. Given this scenario, could the current observable migration of birds (the “dinosaurian offspring”) now be related? Migration is the regular seasonal movement undertaken by many species of birds, with the most common pattern, flying north in the Northern spring to breed in the temperate or Arctic summer and returning in the Northern autumn to wintering grounds in warmer regions of the south. The primary motivation for migration appears to be food. None of the major North-South migratory pathways fly over the Caribbean but three main fly ways, past to the west of the theorized K-T impact centre. Due to their ability to fly, the “avian Dinosaurs” adapted and survived very quickly in response to the disaster that marked the K-T boundary. It is an interesting speculation that the avian migration that we witness today is rooted in an event that occurred 66 million years ago! But it does explain why the migratory birds mostly fly from Polar summer to polar summer when they could just be as easily fly from Polar zone to the warmer equatorial region and back. In the recent article in Nature by Melanie During about identifying the late spring timing of the “Astro disaster”, it can be cited as consistent with my speculation. A late April early May Impact as suggested by During would have seen these migrations completely. The western migratory routes would have been found to be “luxurious” in vegetation in that first northern autumn after the “Astro-impact” while all eastern routes would have still been barren.

关键词： Dinosaur Clades K-T Mass Extinction Avian Migration Migratory Pathways Avian Dinosaurs K-T Impact Centre

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Demineralized Bone Matrix Fibers plus Allograft Bone for Multilevel Posterolateral Spine Fusion: A Game Changer?

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Open Journal of Orthopedics 2024年第2期14卷 105-113页

作者： Bodin Arnaud Barnouin laurence Coulomb Remy Haignere Vincent Kouyoumdjian Pascal Department of Orthopaedic and Traumatological Spine Surgery Groupe Hospitalier Mutualiste Grenoble France Tissue Bank of France Mions France Department of Orthopaedic and Traumatologic Surgery & Spinal Surgery Centre Hospitalier Universitaire N&icircmes France LMGC Université de Montpellier CNRS Montpellier France

Introduction: While autograft bone is the gold standard for multilevel posterolateral lumbar fusion, bone substitutes and graft extenders such as allograft bone, ceramics and demineralized bone matrix (DBM) have been used to avoid the morbidity and insufficient quantity associated with harvesting autologous bone. The primary objective of this retrospective study was to determine whether, in patients with increased risk of operative nonunion related to multilevel fusion, adding DBM fibers to mineralized bone allograft resulted in better fusion than using allograft alone. The secondary objectives were to evaluate how adding DBM fibers affects functional disability, low back pain, intraoperative blood loss and the nonunion rate. Methods: This retrospective study involved a chart review of consecutive patients who underwent multilevel lumbar spinal fusion and were operated on by a single surgeon. The patients were divided into two groups: 14 patients received mineralized bone allograft (control group) and 14 patients received a combination of mineralized bone allograft and DBM (experimental group). Patients were reviewed at a mean of 16.4 ± 2.2 months after surgery at which point CT scans were analyzed to determine whether fusion had occurred;Oswestry disability index (ODI) and pain were also evaluated. Results: A mean of 5 levels [min 2, max 13] were fused in these patients. Posterolateral fusion as defined by the Lenke classification was not significantly different between groups. The experimental DBM group had a significantly better composite fusion score than the control group (P Discussion: Adding DBM fibers to allograft bone during multilevel posterolateral spinal fusion was safe and produced better composite fusion than using allograft only as an autograft extender.

关键词： Spine Surgery Demineralized Bone Fibers Bone Substitutes Retrospective Study

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Semisynthetic Derivatives of Sissotrin Isolated from Trifolium baccarinii Chiov. (Fabaceae) and Evaluation of Their Antibacterial Activities

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Advances in Biological Chemistry 2024年第1期14卷 27-39页

作者： Donald Léonel Feugap Tsamo Cyrille Ngoufack Tagousop Arnaud Joseph Nguetse Dongmo laurence Voutquenne-Nazabadioko David Ngnokam Research Unit of Applied and Environmental Chemistry Department of Chemistry Faculty of Science University of Dschang Dschang Cameroon Department of Organic Chemistry Faculty of Science University of Yaoundé I Yaoundé Cameroon Department of Basic Scientific Studies University Institute of Technology University of Ngaoundéré Ngaoundéré Cameroon Groupe Isolement et Structure Institut de Chimie Moléculaire de Reims (ICMR) Reims France

Starting from sissotrin (1), a natural isoflavonoid isolated from Trifolium baccarinii (Fabaceae), one new semisynthetic derivative, 6-nitrobiochanin A (1b) and two known derivatives, 8-nitrobiochanin A (1a) and 2",3",4",6"-tetraacetylsissotrin (1c) have been obtained after performing nitration and acetylation reactions. Their structures were assigned after interpretation of their spectrometric (HR-ESI-MS) and spectroscopic (NMR 1D and 2D) data and by comparison with those reported in the literature. The substrate as well as the semisynthetic derivatives were evaluated for their antibacterial activities against six strains. The results reveal that they are inactive or weakly active on the strains tested with the exception of 8-nitrobiochanin A (1a) which showed moderate activity (MIC = 62.5 μg∙mL−1) on Staphylococcus aureus ATCC 43300.

关键词： Trifolium baccarinii Isoflavonoid Nitration Acetylation Antibacterial Activity

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Epidemiological derivation of fl ux-based critical levels for visible ozone injury in European forests

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Journal of Forestry Research 2020年第5期31卷 1509-1519页

作者： Pierre Sicard Alessandra De Marco Elisa Carrari laurence dalstein-richier Yasutomo Hoshika Ovidiu Badea Diana Pitar Silvano Fares Adriano Conte Ionel Popa Elena Paoletti ARGANS 260 route du Pin Montard06410 BiotFrance ENEA Via Anguillarese 30100123 Santa Maria di GaleriaItaly IRET-CNR Via Madonna del Piano 1050019 Sesto FiorentinoItaly GIEFS 69 avenue des Hespérides06300 NiceFrance INCDS 128 Eroilor Bvd.077030 VoluntariRomania CREA Viale S.Margherita 8052100 ArezzoItaly

The European MOTTLES project set-up a newgeneration network for ozone(O 3)monitoring in 17 plots in France,Italy and Romania.These monitoring stations allowed:(1)estimating the accumulated exposure AOT40 and stomatal O 3 fl uxes(PODY)with an hourly threshold of uptake(Y)to represent the detoxifi cation capacity of trees(POD1,with Y=1 nmol O 3 m^−2 s^−1 per leaf area);and(2)collecting data of forest-response indicators,i.***.crown defoliation and visible foliar O 3-like injury over the time period 2017–2019.The soil water content was the most important parameter aff ecting crown defoliation and was a key factor aff ecting the severity of visible foliar O 3-like injury on the dominant tree species in a plot.The soil water content is thus an essential parameter in the PODY estimation,particularly for water-limited environments.An assessment based on stomatal fl ux-based standard and on real plant symptoms is more appropriated than the exposure-based method for protecting vegetation.From fl ux-eff ect relationships,we derived fl ux-based critical levels(CLef)for forest protection against visible foliar O 3-like injury.We recommend CLef of 5 and 12 mmol m^−2 POD1 for broadleaved species and conifers,respectively.Before using PODY as legislative standard in Europe,we recommend using the CLec for≥25%of crown defoliation in a plot:17,000 and 19,000 nmol mol^−1 h AOT40 for conifers and broadleaved species,respectively.

关键词： POD Critical levels Ozone Visible injury Epidemiology

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Bridging experimental and monitoring research for visible foliar injury as bio-indicator of ozone impacts on forests

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Ecosystem Health and Sustainability 2022年第1期8卷 295-309页

作者： Barbara Baesso Moura Elisa Carrari laurence dalstein-richier Pierre Sicard Stefan Leca Ovidiu Badea Diana Pitar-Silaghi Anumol Shashikumar Marie-Lyne Ciriani Elena Paoletti Yasutomo Hoshika aInstitute of Research on Terrestrial Ecosystems(IRET) National Research Council of Italy(CNR)Sesto FiorentinoItaly Dipartimento di Scienze e Tecnologie Agrarie Alimentari Ambientali e Forestali(DAGRI)Universitàdegli Studi Firenze(UNIFI)FirenzeItaly GIEFS(Groupe International d'Etudes des Forêts Sud-européennes) NiceFrance ARGANS France Faculty of Silviculture and Forest Engineering “Transilvania”UniversityBraşovRomania National Institute for Research and Development in Forestry“Marin Dracea” VoluntariIlfovRomania

Tropospheric ozone(O_(3))is a phytotoxic air pollutant and the O_(3)-induced visible foliar injury(O_(3)VFI)is a biomarker.A recently developed Free-air O_(3)eXposure(FO_(3)X)is a promising facility to verify field-observed“O_(3)-like”VFIs and to establish a flux-based threshold for the O_(3)VFI onset.The present study compared O_(3)-like VFI registered in the southern European forest sites with actual O_(3)VFI observed in a FO_(3)X experiment.The O_(3)-like VFIs were evaluated by eye in forests and thus it was subjective.According to the imaging analysis,we firstly demonstrated that major parts of the colors were similar in the field and the FO_(3)X.The color pallets for O_(3)VFI was species-specific and considered a advanced tool for the O_(3)VFI diagnosis.In addition,we calculated a flux-based threshold for the O_(3)VFI onset at the FO_(3)X based on a Phytotoxic Ozone Dose(POD_(1)),which ranged from 4.9 to 18.1 mmol m^(-2)POD1.This FO_(3)X-derived threshold partly explained but did not necessarily match with the observation for several tree species in actual forests.The multivariate analysis showed that O_(3)VFI was decreased by the presence of various species and suggested the importance of continuous monitoring activities in the field for the further analysis.

关键词： Ozone visible foliar injury FO3X MOTTLES forest monitoring

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Cardiac Surgery at Yaoundé General Hospital by a Local Team: Activity Report from September 2022 to January 2024

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World Journal of Cardiovascular Surgery 2024年第6期14卷 87-94页

作者： laurence Carole Ngo Yon Charles Mve Mvondo Hermann Nestor Tsague Kengni Zephanie Kobe Fokalbo Sépolin Lowe Mireille Dakleu Alain Patrick Menanga William Ngatchou Djomo Vincent De Paul Djientcheu Department of Cardiothoracic and Vascular Surgery Yaound General Hospital Yaound Cameroon Department of Surgery and Specialities Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Clinical Sciences Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Clinical Sciences Faculty of Medicine and Biomedical Sciences University of Yaound Yaound Cameroon Department of Surgery and Specialities Faculty of Medicine and Biomedical Sciences University of Yaound Yaound Cameroon

Introduction: The practice of cardiac surgery (CS) in sub-Saharan Africa faces a number of challenges. We report on the surgical activities of the first 17 months of the program launched at the Yaoundé General Hospital (YGH), describing the types of interventions and the early results. Patients and Methods: This was a descriptive cross-sectional study including patients who underwent CS from September 2022 to January 2024 at the YGH. Clinical, operative and postoperative data were collected and analysed retrospectively by R software. Results: A total of 37 patients underwent CS during the study period, divided into 23 (62.2%) open-heart and 14 (37.8%) closed-heart cases. Males predominated (sex ratio 1.17). The median age and interquartile range (IQR) were 36 years (9 - 51). Isolated valve surgery, in 15 (40.5%) cases, was the most common procedure in open-heart surgery cases. Closed-heart surgery involved closure of the patent ductus arteriosus in 9 (24.3%) cases, coronary artery bypass grafting in 3 (8.1%) cases, and pericardectomy in 2 (5.4%) cases. The median duration of extracorporeal circulation and aortic cross-clamping was 101 min (IQR 84 - 143) and 74 min (IQR 54 - 112) respectively. The median duration of mechanical ventilation was 2 hours (IQR 2 - 3). The median intensive care unit stay and median hospital stay were 2 days (IQR 2 - 3) and 7 days (IQR 5 - 8) respectively. Operative mortality was 2 (5.4%). Conclusion: Cardiac surgery remains a major challenge for African populations. The early results achieved by the local team are satisfactory. An increase in surgical activity should be strongly encouraged to facilitate local training and ensure the sustainability of the activity.

关键词： Cardiac Surgery Sub-Saharan Africa Cameroon

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Urban heat mitigation by green and blue infrastructure:Drivers,effectiveness,and future needs

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The Innovation 2024年第2期5卷 145-166页

作者： Prashant Kumar Sisay E.Debele Soheila Khalili Christos H.Halios Jeetendra Sahani Nasrin Aghamohammadi Maria de Fatima Andrade Maria Athanassiadou Kamaldeep Bhui Nerea Calvillo Shi-Jie Cao Frederic Coulon Jill L.Edmondson David Fletcher Edmilson Dias de Freitas Hai Guo Matthew C.Hort Madhusudan Katti Thomas Rodding Kjeldsen Steffen Lehmann Giuliano Maselli Locosselli Shelagh K.Malham Lidia Morawska Rajan Parajuli Christopher D.F.Rogers Runming Yao Fang Wang Jannis Wenk laurence Jones Global Centre for Clean Air Research(GCARE) School of SustainabilityCivil and Environmental EngineeringFaculty of Engineering and Physical SciencesUniversity of SurreyGuildford GU27XHUK Institute for Sustainability University of SurreyGuildford GU27XHSurreyUK School of Built Environment University of ReadingWhiteknightsReading RG66BUUK School Design and the Built Environment Curtin University Sustainability Policy InstituteKent StBentley 6102Western Australia Harry Butler Institute Murdoch UniversityMurdoch 6150Western Australia Atmospheric Sciences Department Institute of AstronomyGeophysics and Atmospheric SciencesUniversity of Sao PauloSao Paulo 05508-090Brazil Met Office FitzRoy RoadExeter EX13PBUK Department of Psychiatry and Nuffield Department of Primary Care Health Sciences Wadham CollegeUniversity of OxfordOxfordUK Centre for Interdisciplinary Methodologies University of WarwickWarwickUK School of Architecture Southeast University2 SipailouNanjing 210096China Cranfield University School of WaterEnvironment and EnergyCranfield MK430ALUK Plants PhotosynthesisSoil ClusterSchool of BiosciencesUniversity of SheffieldSheffield S102TNUK UK Centre for Ecology&Hydrology Environment Centre WalesDeiniol RoadBangor LL572UWUK Air Quality Studies Department of Civil and Environmental EngineeringThe Hong Kong Polytechnic UniversityHong KongChina Department of Forestry and Environmental Resources Faculty Excellence Program for Leadership in Public ScienceNorth Carolina State UniversityChancellorRaleighNC 27695USA Departments of Architecture&Civil Engineering and Chemical EngineeringUniversity of BathBath BA27AYUK School of Architecture University of NevadaLas VegasNV 89154USA Department of Tropical Ecosystems Functioning Center of Nuclear Energy in AgricultureUniversity of São PauloPiracicaba 13416-000Sao PauloBrazil School of Ocean Sciences Bangor UniversityMenai BridgeAnglesey LL595 ABUK International Laboratory for Air Quality and Health Science and Engine

The combination of urbanization and global warming leads to urban overheating and compounds the frequency and intensity of extreme heat events due to climate change.Yet,the risk of urban overheating can be mitigated by urban green-blue-grey infrastructure(GBGI),such as parks,wetlands,and engineered greening,which have the potential to effectively reduce summer air temperatures.Despite many reviews,the evidence bases on quantified GBGI cooling benefits remains partial and the practical recommendations for implementation are unclear.This systematic literature review synthesizes the evidence base for heat mitigation and related co-benefits,identifies knowledge gaps,and proposes recommendations for their implementation to maximize their benefits.After screening 27,486 papers,202 were reviewed,based on 51 GBGI types categorized under 10 main divisions.Certain GBGI(green walls,parks,street trees)have been well researched for their urban cooling capabilities.However,several other GBGI have received negligible(zoological garden,golf course,estuary)or minimal(private garden,allotment)attention.The most efficient air cooling was observed in botanical gardens(5.0±3.5℃),wetlands(4.9±3.2℃),green walls(4.1±4.2℃),street trees(3.8±3.1℃),and vegetated balconies(3.8±2.7℃).Under changing climate conditions(2070–2100)with consideration of RCP8.5,there is a shift in climate subtypes,either within the same climate zone(e.g.,Dfa to Dfb and Cfb to Cfa)or across other climate zones(e.g.,Dfb[continental warm-summer humid]to BSk[dry,cold semi-arid]and Cwa[temperate]to Am[tropical]).These shifts may result in lower efficiency for the current GBGI in the future.Given the importance of multiple services,it is crucial to balance their functionality,cooling performance,and other related co-benefits when planning for the future GBGI.This global GBGI heat mitigation inventory can assist policymakers and urban planners in prioritizing effective interventions to reduce the risk of urban overheating,filling research gaps,and promoting community resi

关键词： estuary walls extreme

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Outpatient insulin use in type 2 diabetes mellitus and acute respiratory distress syndrome outcomes:A retrospective cohort study

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World Journal of Clinical Cases 2024年第17期12卷 2966-2975页

作者： Georges Khattar Samer Asmar laurence Aoun Fares Saliba Shaza Almardini Saif Abu Baker Catherine Hong Carolla El Chamieh Fadi Haddadin Toni Habib Omar Mourad Zeina Morcos Fatema Arafa Jonathan Mina Khalil El Gharib Mohammad Aldalahmeh Salman Khan Elie Bou Sanayeh Department of Medicine Holy Spirit University of KaslikJounieh 00000Lebanon Department of Internal Medicine Staten Island University HospitalStaten IslandNY 10305United States Public Heath and Biostatistics Independent ResearchBeirut 0000Lebanon Department of Medicine Lebanese UniversityBeirut 00000Lebanon Department of Medicine University of BalamandBeirut 00000Lebanon Department of Medicine Lebanese American UniversityBeirut 00000Lebanon Department of Medicine Northwell Health Staten Island University HospitalNew YorkNY 10305United States

BACKGROUND The impact of type 2 diabetes mellitus(T2DM)on acute respiratory distress syndrome(ARDS)is debatable.T2DM was suspected to reduce the risk and complications of ARDS.However,during coronavirus disease 2019(COVID-19),T2DM predisposed patients to ARDS,especially those who were on insulin at home.AIMTo evaluate the impact of outpatient insulin use in T2DM patients on non-COVID-19 ARDS outcomes.METHODS We conducted a retrospective cohort analysis using the Nationwide Inpatient Sample database.Adult patients diagnosed with ARDS were stratified into insulin-dependent diabetes mellitus(DM)(IDDM)and non-insulindependent DM(NIDDM)groups.After applying exclusion criteria and matching over 20 variables,we compared cohorts for mortality,duration of mechanical ventilation,incidence of acute kidney injury(AKI),length of stay(LOS),hospitalization costs,and other clinical outcomes.RESULTS Following 1:1 propensity score matching,the analysis included 274 patients in each group.Notably,no statistically significant differences emerged between the IDDM and NIDDM groups in terms of mortality rates(32.8%vs 31.0%,P=0.520),median hospital LOS(10 d,P=0.537),requirement for mechanical ventilation,incidence rates of sepsis,pneumonia or AKI,median total hospitalization costs,or patient disposition upon discharge.CONCLUSION Compared to alternative anti-diabetic medications,outpatient insulin treatment does not appear to exert an independent influence on in-hospital morbidity or mortality in diabetic patients with non-COVID-19 ARDS.

关键词： Acute respiratory distress syndrome Type 2 diabetes mellitus Insulin Length of stay Mortality Endotracheal intubation Acute kidney injury Coronavirus disease 2019

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