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LinkLongman welcome to English listening skills. 6A-6B / Don dallas, Linda Pelham

2005年

作者： Don. dallas

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Recent advances in traffic signal performance evaluation

2005年

作者： dallas Don

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Journal of Traffic and Transportation Engineering(English Edition) 2022年第4期9卷 507-531页

作者： dallas Leitner Piro Meleby Lei Miao Department of Engineering Technology Middle Tennessee State UniversityMurfreesboroTN 37132USA

Signal retiming is a prominent way that transportation agencies use to fight congestion and change of traffic *** evaluations of traffic conditions at signalized intersections and arterials provide actionable data for agencies to make well-informed and prioritized signal retiming ***,the abundance of data sources,the lack of standardized evaluation methods and oftentimes the shortage of resources make it a difficult *** review detailed in this paper examines the advances made in traffic signal performance *** establish the necessity for the evaluations,study the process of continuous improvement of traffic signal performance using the evaluations,and then examine multiple methodologies in a plethora of research ***,we focus on probe vehicles and sensors data,the two major sources of *** discuss how sensors are connected to signal controllers to provide relevant in-depth traffic data including speed and occupancy *** also review the nature of probe vehicles and the level of *** then define and summarize performance measures derived from both sources,to aid in performance *** performance evaluation methods,we discuss the research studies and provide summaries including advantages and disadvantages of the methods used,as well as a holistic outlook for future *** paper is aimed to provide a comprehensive review on the state-of-the-art to benefit researcher,traffic agencies,and commercial entities that thrive to improve safety and efficiency of traffic signals through performance evaluations.

关键词： Intelligent transportation systems Traffic signal performance evaluation Traffic signal retiming Traffic signals optimization Intersection control evaluation

Epidemic time series similarity is related to geographic distance and age structure

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Infectious Disease Modelling 2022年第4期7卷 690-697页

作者： Tad A.dallas Grant Foster Robert L.Richards Bret D.Elderd Department of Biological Sciences University of South CarolinaColumbiaSC29208USA Department of Biological Sciences Louisiana State UniversityBaton RougeLA70802USA

Objective:More similar locations may have similar infectious disease *** is clear overlap in putative causes for epidemic similarity,such as geographic distance,age structure,and population *** compare the effects of these potential drivers on epidemic similarity compared to a baseline assumption that differences in the basic reproductive number(R0)will translate to differences in epidemic ***:Using COVID-19 case counts from United States counties,we explore the importance of geographic distance,population size differences,and age structure dissimilarity on resulting epidemic ***:We find clear effects of geographic space,age structure,population size,and R0 on epidemic similarity,but notably the effect of age structure was stronger than the baseline assumption that differences in R0 would be most related to epidemic ***:Together,this highlights the role of spatial and demographic processes on SARS-CoV2 epidemics in the United States.

关键词： Epidemic similarity SARS-CoV2 Age structure Distance decay

TLR2 and TLR4-mediated inflammation in Alzheimer's disease: self-defense or sabotage?

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Neural Regeneration Research 2021年第8期16卷 1552-1553页

作者： Mark L.dallas Darius Widera Cellular Neuroscience School of PharmacyUniversity of ReadingReadingUK Stem Cell Biology and Regenerative Medicine Group School of PharmacyUniversity of ReadingWhiteknights campusReadingUK

Alzheimer's disease(AD) is an irreversible disease that leads to *** underpinning mechanisms of neuronal cell death are a matter of ongoing debate regarding the impact of accumulation of the amyloid beta(Aβ)peptide and post-translation modifications of the tau ***,a growing area of research and one that may provide a more rigorous account of the early changes seen in Alzheimer's brains is inflammation.

关键词： Alzheimer Aβ tau TLR2 TLR4

Herbicide resistance: Development of wheat production systems and current status of resistant weeds in wheat cropping systems

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The Crop Journal 2019年第6期7卷 750-760页

作者： Sridevi Nakka Mithila Jugulam dallas Peterson Mohammad Asif Heartland Plant Innovations ManhattanKS 66506USA Department of Agronomy Kansas State University2004 Throckmorton Plant Sciences CenterManhattanKS 66506USA

Herbicide resistance in crops has extended the scope of herbicide applications to control weeds. The introduction of herbicide resistant crops resulted in a major shift in the way that herbicides are used in many crops, but not necessarily increased the prevalence of herbicide use, especially in wheat. Wheat is one of the most widely grown crops in the world and currently only two major herbicide-resistant wheat groups have been commercialized to manage weeds in a cost-effective manner. However, sustainable wheat production is threatened by the expanding occurrence of herbicide-resistant weed populations with limited efforts to discover new herbicide molecules. Selective control of certain problematic weeds in wheat was impossible until development and introduction of the technologies, Clearfield and Co AXium Production Systems. However, the current limitations of reliance on specific herbicides and evolution of resistant weeds mandate precautions and considerations when using these systems to prevent the loss of existing herbicide resources and continue sustainable wheat production. The focus of this review is to provide an overview of natural pre-existing herbicide resistance and development of herbicide-resistant technologies in wheat. The mechanisms of resistance to herbicides in wheat as well as the weed populations in wheat cropping systems, and implications for weed management are discussed.

关键词： Clearfield Coaxium Cytochrome P450s GSTs Herbicide resistance Wheat production systems

SOPHIE: Generative Neural Networks Separate Common and Specific Transcriptional Responses

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Genomics, Proteomics & Bioinformatics 2022年第5期20卷 912-927页

作者： Alexandra J.Lee dallas L.Mould Jake Crawford Dongbo Hu Rani K.Powers Georgia Doing James C.Costello Deborah A.Hogan Casey S.Greene Genomics and Computational Biology Graduate Program University of PennsylvaniaPhiladelphiaPA 19104USA Department of Microbiology and Immunology Geisel School of Medicine at DartmouthHanoverNH 03755USA Department of Systems Pharmacology and Translational Therapeutics University of PennsylvaniaPhiladelphiaPA 19104USA Wyss Institute for Biologically Inspired Engineering Harvard UniversityBostonMA 02115USA Department of Pharmacology University of Colorado School of MedicineDenverCO 80045USA Center for Health AI University of Colorado School of MedicineDenverCO 80045USA Department of Biochemistry and Molecular Genetics University of Colorado School of MedicineDenverCO 80045USA

Genome-wide transcriptome profiling identifies genes that are prone to differential expression(DE)across contexts,as well as genes with changes specific to the experimental *** genes that are specifically changed in a context of interest from common differentially expressed genes(DEGs)allows more efficient prediction of which genes are specific to a given biological process under ***,common DEGs or pathways can only be identified through the laborious manual curation of experiments,an inordinately time-consuming *** we pioneer an approach,Specific cOntext Pattern Highlighting In Expression data(SOPHIE),for distinguishing between common and specific transcriptional patterns using a generative neural network to create a background set of experiments from which a null distribution of gene and pathway changes can be *** apply SOPHIE to diverse datasets including those from human,human cancer,and bacterial pathogen Pseudomonas *** identifies common DEGs in concordance with previously described,manually and systematically determined common *** molecular validation indicates that SOPHIE detects highly specific but low-magnitude biologically relevant transcriptional ***’s measure of specificity can complement log2 fold change values generated from traditional DE *** example,by filtering the set of DEGs,one can identify genes that are specifically relevant to the experimental condition of ***,these results can inform future research *** scripts used in these analyses are available at https://***/greenelab/*** can access https://***/greenelab/sophie to run SOPHIE on their own data.

关键词： Neural network Transcriptomics Software Differential expression analysis Machine learning

COVID-19 Mortality and Vaccine Coverage——Hong Kong Special Administrative Region,China,January 6,2022-March 21,2022

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China CDC weekly 2022年第14期4卷 288-292页

作者： dallas J.Smith Avi J.Hakim Gabriel M.Leung Wenbo Xu WWilliam Schluter Ryan T.Novak Barbara Marston Bradley S.Hersh CDC COVID-19 Response International Task Force Atlanta Epidemic Intelligence Service CDC Li Ka Shing Faculty of Medicine University of Hong KongHong Kong Special Administrative RegionChina National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina CDC China BeijingChina

Summary What is already known about this topic?COVID-19 vaccines are important tools to protect populations from severe disease and *** is added by this report?Among persons aged≥60 years in Hong Kong,49%,had received≥2 doses of a COVID-19 vaccine,and vaccination coverage declined with *** January-March 2022,reported COVID-19-associated deaths rose rapidly in Hong *** these deaths,96%occurred in persons aged≥60 years;within this age group,the risk for death was 20 times lower among those who were fully vaccinated compared with those who were unvaccinated.

关键词： doses COV deaths

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The devil wins

The devil wins

CHEMICAL VAPOR DEPOSITION OF DIFFUSION BARRIERS FOR ADVANCED METALLIZATION

作者： (1964-)Denery dallas G.

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化工学报 2000年第S1期51卷 5-9页

作者： Lu Jiong-Ping (Silicon Technology Research, Texas Instruments, dallas, USA)

Metalization is widely used in integrated circuit devices to connect millions of devices together. The success of metallization depends strongly on diffusion barrier technology, due to the interactions of metals with surrounding materials. As device dimension further shrinks, diffusion barrier technology is facing more challenges and opening up new opportunities, particularly for chemical vapor deposition (CVD) process technology. CVD is attracting increased attention in advanced metallization mainly due to its capability in producing conformal thin films. In this review, we will focus our discussion on CVD processes for three most important classes of diffusion barriers: Ti, W and Ta-based diffusion banters. Examples from current literature will be examined.

关键词： chemical vapor deposition diffusion bather TiN TiSiN WN TaN metallization integrated circuits