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一座大跨弧形变高度钢桁架人行天桥设计研究

城市道桥与防洪 2024年第6期 87-89页

作者：毛远文聂细锋张大军贵阳市城市建设投资集团有限公司贵州贵阳580023 中铁二院贵阳勘察设计研究院有限责任公司贵州贵阳550002

以某大跨弧形变高度钢桁架人行天桥为设计背景,通过建立空间有限元模型,与取消竖杆后的钢桁架、等高度钢桁架和钢管桁架进行对比分析,得出:当节间距较小时,竖杆对整体竖向刚度的影响小于对整体结构质量的影响,取消竖向后可以增加结构的... 详细信息

以某大跨弧形变高度钢桁架人行天桥为设计背景,通过建立空间有限元模型,与取消竖杆后的钢桁架、等高度钢桁架和钢管桁架进行对比分析,得出:当节间距较小时,竖杆对整体竖向刚度的影响小于对整体结构质量的影响,取消竖向后可以增加结构的固有频率;弧形钢桁架会导致整体竖向刚度下降,常规条件下宜选用等高度桁架形式,可降低桁架高度,节约用钢量;钢管桁架能更好地发挥材料特性,较箱形桁架能较大地发挥截面特性,能减少用钢量和焊接工作量。研究结果可为今后同类人行天桥提供一定的借鉴和参考意义。

关键词：竖向自振频率变高度钢桁架等高度钢桁架钢管桁架对比分析桁架高度

IMPACT RESPONSE OF LOWER-LIMBS OF VEHICLE OCCUPANT IN FRONTAL CRASHES CONSIDERING INTRUSION

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Chinese Journal of Mechanical Engineering 1998年第4期11卷 42-46页

作者： Wang Shuxin zhang dajun Han Xiaolan Liu Youwu College of Mechanical Engineering, Tianjin University Tianjin Univ Tianjin China

The lower extremity forces developed during vehicle accidents with significant floor pan intrusion are considered, and the forces generated directly by the intrusion are focused on. The analysis is based on the modification and use of SUPERCRASH a multibody crash computer simulator. For 48 km/h frontal collisions, the results show that there is marked asymmetry on the forces exerted on the left and right legs, arising due to the asymmetrical restraint of the 3 point seat belts. The results also show, as expected, that floor pan intrusion reduction will greatly reduce the forces on the lower extremities.

关键词： Frontal crash Intrusion Dynamics

非洲猪瘟病毒D1133L蛋白增加宿主波形蛋白磷酸化而促进病毒在猪巨噬细胞中的复制

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微生物学报 2024年第3期64卷 720-732页

作者：陈玲玲张婷郝雨杨金柯史喜绢张大俊杨行赵登率闫文倩别鑫恬陈国辉郑海学乐涛张克山重庆师范大学生命科学学院重庆401331 中国农业科学院兰州兽医研究所/兰州大学动物医学与生物安全学院动物疫病防控全国重点实验室甘肃兰州730000

非洲猪瘟(African swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)感染引起家猪和野猪的一种高死亡率的传染性疾病。ASFV具有庞大的基因组,其中非结构蛋白pD1133L被预测为其编码的6个解旋酶之一。本实验室应用免疫... 详细信息

非洲猪瘟(African swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)感染引起家猪和野猪的一种高死亡率的传染性疾病。ASFV具有庞大的基因组,其中非结构蛋白pD1133L被预测为其编码的6个解旋酶之一。本实验室应用免疫沉淀-质谱联用(immunoprecipitation-mass spectrometry,IP-MASS)技术筛选与pD1133L互作的宿主细胞蛋白,发现细胞波形蛋白(vimentin,VIM)为pD1133L互作的宿主蛋白之一,但尚不清楚宿主蛋白VIM对ASFV复制的影响。【目的】探究ASFV与VIM的相互调控作用,揭示VIM促进ASFV复制的机制。【方法】通过免疫共沉淀(co-immunoprecipitation,Co-IP)试验验证pD1133L与VIM存在互作关系;外源过表达VIM蛋白以及设计并合成VIM的si RNA探究VIM对ASFV复制的影响;利用Western blotting以及荧光定量PCR(quantitative real-time PCR,qPCR)方法检测ASFV对VIM蛋白水平以及转录水平的影响;通过Western blotting、间接免疫荧光试验(immunofluorescence assay,IFA)探究巨噬细胞感染ASFV后VIM磷酸化水平变化以及亚细胞定位变化情况;CCK-8试剂盒检测VIM磷酸化抑制剂KN-93处理的最佳浓度,并利用Western blotting以及IFA检测KN-93对VIM磷酸化、亚细胞定位以及对ASFV复制影响。【结果】VIM过表达促进ASFV复制,敲低VIM的表达则抑制ASFV复制;ASFV感染抑制VIM蛋白水平以及转录水平表达,且呈时间依赖性;ASFV感染后VIM发生磷酸化修饰且发生亚细胞定位改变,从而促进ASFV复制。【结论】证实了ASFV与宿主蛋白VIM之间的相互调控作用;初步确定ASFV感染后VIM受到ASFV pD1133L调控,亚细胞定位发生重排向核周聚集从而促进ASFV复制的机制。

关键词：非洲猪瘟病毒 D1133L蛋白波形蛋白蛋白互作磷酸化

COMPUTER AIDED ANALYSIS OF FLEXI－BLE MEMBER IN CONSIDERATION OF THE EFFECTS OF DYNAMIC STI－FFEN－ING

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Chinese Journal of Mechanical Engineering 1994年第4期7卷 257-267页

作者： zhang dajun Liu Youwu Huston Ronald L(Tianjin University)

A recently developed procedure to capture the dynamic stiffening of an arbitrary flexiblemember in large overall motion accompanied by small elastic vibrations is presented. A mechanicalsystem that consists of one or more flexible members is called a flexible mechanical system. If thesystem is considered as a multibody system, the flexiblemember can be considered as a flexible bodyin a flexible multibody system. Having retained the nonlinearitites up to an appropriate point in theanalysis, the linearization is then performed properiy so that the dynamic stiffening terms can befound naturally, while the explicit formulation of the governing equations for the deformation mo-tion is ultimately linear. Based on the procedure, the effects of dynamic stiffening are investigatedqualitatively and quantitatively with analytical and numerical examples. The results are useful incomputer aid analysis of the dynamic behavior of flexible mechanical systems.

关键词： Dynamic stiffening Flexible member Multibody dynamics Kane's equations

健康体检人群非酒精性脂肪肝患病现状及共病相关性分析

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中国煤炭工业医学杂志 2024年第3期27卷 307-312页

作者：石卓跃杨颖韩金慧张大军郑帅印李砥新疆医科大学公共卫生学院新疆维吾尔自治区乌鲁木齐市830000 新疆维吾尔自治区人民医院克拉玛依医院临床医学研究中心新疆维吾尔自治区人民医院克拉玛依医院健康管理中心新疆第二医学院教务处新疆消化系统肿瘤精准医疗临床医学研究中心新疆临床基因检测与生物医学信息重点实验室

目的探讨克拉玛依市健康体检人群非酒精性脂肪肝(NAFLD)的患病现状及肝、胆、肾脏共病患病情况,并分析相关共病与NAFLD的相关影响。方法选择2019年1月—2019年12月在克拉玛依市中心医院健康管理中心体检的45591例作为研究对象,描述性分... 详细信息

目的探讨克拉玛依市健康体检人群非酒精性脂肪肝(NAFLD)的患病现状及肝、胆、肾脏共病患病情况,并分析相关共病与NAFLD的相关影响。方法选择2019年1月—2019年12月在克拉玛依市中心医院健康管理中心体检的45591例作为研究对象,描述性分析不同性别、民族、年龄、肝脏疾病及其它相关共病分布特征,采用二分类Logistic回归分析相关影响因素。结果克拉玛依市NAFLD患病率为22.19%,男性患病率高于女性(P<0.05),随着年龄的增长呈现递增的趋势;50.88%NAFLD患者同时患胆囊相关疾病,30.53%NAFLD患者同时患有肾脏相关疾病;脾脏其他异常、肾错构瘤、肾结石、肾积水、肝肾囊肿以及肾脏其他异常与脂肪肝均存在正相关关系,肝血管瘤和其他肝脏疾病与脂肪肝呈负相关。Logistic回归分析结果显示胆结石、胆囊息肉、胆囊切除术、胆囊炎、胆固醇沉着、肝囊肿、脾大、脾脏其他异常、肾结石、肾囊肿、肾脏其他异常可能是脂肪肝的危险因素(P<0.05)。结论克拉玛依市居民NAFLD患病现状不容乐观,相关卫生部门应予以重视并针对其共病开展健康教育和重点防控,从而降低NAFLD患病率,提高生活质量和幸福指数。

关键词：健康体检非酒精性脂肪肝影响因素

基于燃气发电提质增效目标的天然气钻井平台微电网系统超级电容储能应用

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内燃机 2024年第3期40卷 59-64页

作者：孙红斌郝利华曲其磊陈新张红艳张大军中国石油集团济柴动力有限公司山东济南250306

由于石油钻井工况复杂多变,负载波动频繁,天然气钻井平台微电网中的内燃机效能普遍较低。本文旨在通过引入超级电容器储能技术,提升燃气发电机组的单机带载率和抗负载冲击能力,同时减少钻井平台微电网中燃气发电机组的投入数量,并优化... 详细信息

由于石油钻井工况复杂多变,负载波动频繁,天然气钻井平台微电网中的内燃机效能普遍较低。本文旨在通过引入超级电容器储能技术,提升燃气发电机组的单机带载率和抗负载冲击能力,同时减少钻井平台微电网中燃气发电机组的投入数量,并优化机组的运行调节,进而实现燃气消耗的降低和发电效率的提高。从现场调试结果来看,超级电容器储能系统在减轻发动机负载冲击、优化机组运行以及减少运行机组数量方面的应用效果十分显著。

关键词：气代油钻井石油天然气发电机发电效率超级电容器储能

Impact of Gender and Working Environment on the Level of State Anxiety among Primary and Middle school Teachers in China

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Journal of Behavioral and Brain Science 2012年第1期2卷 102-107页

作者： Lijuan Wang dajun zhang Center for Psychological Health Research & School of Psychology Southwest University Chongqing Chin Center for Psychological Health Research & School of Psychology Southwest University Chongqing China

State anxiety has become serious among primary and middle school teachers in China. By using stratified random sampling, we selected 2790 primary and middle school teachers as participants. They were from seven regions of China, among them 2278 were valid subjects. Constructed on the basis of anxiety content, the Teachers’ State Anxiety Questionnaire (TSAQ) was used in the investigation. The result of the survey shows that primary and middle school teachers are generally affected by state anxiety;further analysis indicates that the prevalence of state anxiety is relatively higher among male teachers, teachers from key middle schools, teachers working more than 10 hours a day, and teachers loaded with additional task as head teachers. This is directly connected with China’s national situation, teaching envi-ronment, discrepancies in teachers themselves, and their own ability of self-regulation.

关键词： Primary and Middle School Teachers State Anxiety Prevalence

The Criticism and Amendment for the Dual-Factor Model of Mental Health: From Chinese Psychological Suzhi Research Perspectives

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International Journal of Clinical Medicine 2012年第5期3卷 319-327页

作者： Xinqiang Wang dajun zhang Key Laboratory of Cognition and Personality of Ministry of Education (Southwest University) & Center for Mental Health Education Southwest University Chongqing China

Aiming at the limitations of psychopathology (PTH), the dual-factor model of mental health (DFM) was proposed as a new mental health concept and methodology under the background of positive psychology trend. In this paper we propose giving an overview of DFM, and doubt, criticize, and modify DFM from the perspective of Chinese psychological suzhi research. The available literature from 1983 to 2012 that is related to DFM and concerning psychological suzhi research in the past 20 years has been reviewed. In addition, we also absorbed the idea of positive psychology and Traditional Chinese Medicine (TCM) Constitution theory to develop theoretically the relationship model between psychological suzhi and mental health. The relationship model between psychological suzhi and mental health modifies and transcends PTH and DFM. It will be the new research area of mental health research.

关键词： Dual-Factor Model of Mental Health Psychopathology Relationship Model between Psychological Suzhi and Mental Health Subjective Well-Being

The Relationship between Psychological Suzhi and Mental Health among Chinese College Students

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Journal of Biosciences and Medicines 2016年第5期4卷 21-29页

作者： Xinqiang Wang Xueqi zhang dajun zhang School of Psychology & Center of Mental Health Education and Research Jiangxi Normal University Nanchang China Center of Mental Health Education and Research Southwest University Chongqing China

Object: To explore the relationship between psychological suzhi and mental health among Chinese college students, and to gain psychological suzhi factors that are predictors for mental health. Method: By using stratified sampling method, an investigation was conducted among 734 subjects. They were assessed with the College Student Psychological Suzhi Scale (CSPS, including 3 subscales, 28 factors) and General Health Questionnaire-20 item (GHQ-20, including 3 subscales). Results: 1) Psychological suzhi score for Chinese college students had negative correlation with the score of GHQ-20, GHQ-depression and GHQ-anxiety (p < 0.001), and positive correlation with the score of GHQ-self-affirmation (p < 0.001);2) Psychological suzhi score for Chinese college students was predictor of the score for GHQ-20 and its subscales namely GHQ-self-affirmation, GHQ-depression, and GHQ-anxiety (β = ?0.448, 0.439, ?0.262, ?0.259, p < 0.001);the variance explained by the score of GHQ-20 and its subscales were 19.9%, 19.1%, 6.7%, 6.5%;3) There were 12 psychological suzhi factors that were predictors for GHQ-self-affirmation which was known as the positive indicator of mental health (p < 0.05);11 psychological suzhi factors were predictors for GHQ-depression and GHQ-anxiety which was known as the negative indicator of mental health (p < 0.05). Conclusion: There exists a correlation between psychological suzhi and mental health, particularly in positive mental health. Indeed, the psychological suzhi factors are able to enhance the pertinence of mental health education.

关键词： Chinese College Students Mental Health Psychological Suzhi Dual-Factor Model of Mental Health