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The 4th Joint China/Japan Chemical Engineering Symposium

作者： Hideki Matsumoto daisuke nagao Mikio Konno Department of Chemical Engineering Tohoku University 6-6-07AobaAramaki-azaAoba-kuSendaiJapan Department of Chemical Engineering Tohoku University 6-6-07AobaAramaki-azaAoba-kuSendaiJapan Department of Chemical Engineering Tohoku University 6-6-07AobaAramaki-azaAoba-kuSendaiJapan

Colloidally stable magnetite （Fe3O4） nanoparticles were prepared with a coprecipitation method in the presence of asilane coupling agent of N-trimethoxysilylpropyl-N,N,N-trimethylammonium chloride （TSA）, which cationizedthe surface of Fe3O4 nanoparticles. The dynamic light scattering （DLS） measurements indicated that the Fe3O4nanoparticles were highly dispersed in nanometer-sizes. Electrophoretic light scattering （ELS） showed that thesurface-modified Fe3O4 nanoparticles have positive surface potential. Heterocoagulation between the positive Fe3O4nanoparticles and the negative silica particles were performed, which produced Fe3O4-silica composite particles with ahigh monodispersity in particle sizes.

关键词： Magnetite Colloidal stability Heterocoagulation Composite particle

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Diffusion-weighted imaging might be useful for reactive lymphoid hyperplasia diagnosis of the liver: A case report

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World Journal of Clinical Cases 2020年第21期8卷 5313-5319页

作者： Taro Tanaka Kazuhiro Saito daisuke Yunaiyama Jun Matsubayashi Yuichi Nagakawa Maki Tanigawa Toshitaka nagao Department of Radiology Tokyo Medical UniversityTokyo 1600023Japan Department of Anatomic Pathology Tokyo Medical UniversityTokyo 1600023Japan Department of Gastrointestinal and Pediatric Surgery Tokyo Medical UniversityTokyo 1600023Japan

BACKGROUND Reactive lymphoid hyperplasia(RLH)of the liver is a rare liver *** is considered difficult to differentiate radiologically from hepatocellular carcinoma,metastatic liver tumor and other *** SUMMARY A 54-year-old woman presented to our hospital with RLH of the *** patient had a diagnosis of metastatic carcinoma of the liver from an unknown origin and subsequently underwent partial ***,histopathological analysis revealed *** lesion showed perinodular enhancement in the arterial phase on contrast-enhanced computed tomography and magnetic resonance *** diffusion-weighted imaging(DWI),we encountered linear hyperintensity along the portal tract consecutive to the liver lesion,which is a new characteristic radiologic *** finding corresponded to the lymphoid cell infiltration of the portal ***,there was strongly restricted diffusion on the apparent diffusion coefficient *** used these characteristic radiologic findings to diagnose the lesion as a lymphoproliferative *** The linear hyperintensity consecutive to the liver lesion on DWI provided additional valuable diagnostic information.

关键词： Reactive lymphoid hyperplasia Pseudolymphoma Magnetic resonance imaging Diffusion-weighted imaging Perinodular enhancement Portal tract infiltration Case report

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Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report

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World Journal of Clinical Cases 2023年第18期11卷 4377-4383页

作者： Akio Sato Kazuhiro Saito Koichiro Abe Katsutoshi Sugimoto Toshitaka nagao Aoi Sukeda daisuke Yunaiyama Department of Radiology Tokyo Medical University HospitalShinjuku-ku 160-0023TokyoJapan Department of Gastroenterology and Hepatology Tokyo Medical University HospitalShinjuku-ku 160-0023TokyoJapan Department of Anatomic Pathology Tokyo Medical University HospitalShinjuku-ku 160-0023TokyoJapan

BACKGROUND As hepatic myelolipoma is rarely encountered,its radiological diagnosis using ultrasonography(US),computed tomography(CT),and magnetic resonance imaging(MRI)is *** myelolipoma is similar to fat-contained hepatic lesions seen in hepatocellular carcinoma and ***,further development of techniques to diagnose hepatic myelolipoma is *** SUMMARY A 44-year-old obese man was found to have a hepatic lesion during his medical *** lesion was 50 mm×57 mm in size and was detected in segment 8(S8)of the liver by *** patient was diagnosed with hepatic lesion 20 years ago,but it was left *** patient had no symptoms,liver dysfunction,hepatitis virus antibody,or tumor marker *** CT showed a welldefined lesion in S8 of the *** central and peripheral areas of the lesion primarily exhibited fat density and hypodensity,*** revealed a capsule-like *** was performed to address the probability of hepatocellular *** lesion was pathologically confirmed as a *** marrow scintigraphy performed using 111InCl3 revealed accumulation of the radiopharmaceutical in the soft tissue component,except in the fat-dominant part of the tumor,as well as in the surrounding liver parenchyma due to the presence of reticuloendothelial cells in the *** This is the first report on the diagnosis of hepatic myelolipoma using 111InCl3 *** effectiveness of bone marrow scintigraphy for diagnosing hepatic myelolipoma might be *** radiopharmaceuticals accumulate in both hematopoietic and reticuloendothelial cells,the accumulation of radiopharmaceuticals in the lesion is obscure.

关键词： Liver 111InCl3 Myelolipoma Magnetic resonance imaging Benign tumor Case report

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The Influence of Sampling Site on Blood Lactate Response to Steady State Exercise

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Journal of Sports Science 2018年第5期6卷 276-284页

作者： Takashi Yamagata daisuke Kume Toshihiro Wakimoto Noriki nagao Department of Human Sciences and Design Japan Women’s University Tokyo 112-8681 Japan Department of Health Sports and Welfare Okinawa University Okinawa 902-8521 Japan Department of Health and Sports Science Kawasaki University of Medical Welfare Kurashiki Okayama 701-0193 Japan Department of Health System Management Hyogo University Hyogo 675-0195 Japan

In sports sciences, blood lactate is commonly measured for performance testing or setting exercise intensity. Differences in measuring lactate concentration over time and across sampling sites during constant exercise are unknown. We aimed to compare blood lactate concentration across sampling sites during constant exercise. Eight participants performed three bouts of 20-min steady-state cycle exercise, consisting of 45, 60, and 75% of peak oxygen uptake (V . O2peak). Blood lactate levels were measured simultaneously from the fingertip and earlobe every 5 min during exercise. The time course analysis revealed that lactate level in the fingertip was significantly higher than in the earlobe at either work intensity (P < 0.05). A significant interaction effect (site x time) was observed at 60% V O2peak (P < 0.001), which indicated that the difference in samples across sampling sites decreased over time. The levels in the fingertip samples were higher at 5 min (P < 0.05);this difference was not noted after 10 min. Similarly, the fingertip values were significantly higher until 10 min (P < 0.05), but not after 15 min at 75% V O2peak. These findings suggest that the sampling site may affect the time course of change in lactate value under a constant workload.

关键词： Lactic acid constant work cycle ergometry lactate steady state

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