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Plantar Spitz Nevus Resembling Malignant Melanoma: Description of Immunohistochemical Findings

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Case Reports in Clinical Medicine 2023年第6期12卷 202-206页

作者： Karen Fukushi Tomohisa Fukui Hajime Nakano daisuke Sawamura Department of Dermatology Hirosaki University Graduate School of Medicine Hirosaki Japan

Spitz nevus (SN) is predominantly distributed throughout the lower extremities, while an acral location is rare. Since SN occasionally resembles the clinicopathological presentation of malignant melanoma (MM), it presents a diagnostic challenge, especially on glabrous skin. Past reports suggest that several genetic aberrations are associated with specific clinicopathological subtypes of melanocytic tumors. Immunohistochemistry can provide a clue to the presence or absence of a molecular aberration typical of Spitz tumors. We describe a case of a plantar SN with genetic analysis, including anaplastic lymphoma kinase (ALK), ROS proto-oncogene 1 (ROS1), BRAF (V600E) protein, and BRCA1-associated protein-1 (BAP1). However, we were not able to detect a characteristic gene aberration. To the best of our knowledge, no genetic aberrations in plantar SN cases have been reported. A comprehensive understanding of tumor genomics is expected to play an essential role in the classification of melanocytic tumors. Further genetic research on plantar SN is required to establish new criteria for distinguishing between SN and MM.

关键词： Spitz Nevus Plantar Malignant Melanoma

Strain-dependence of deformation microstructures in ultra-low-C IF steel deformed to high strains by torsion at elevated temperatures

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Nano Materials Science 2020年第1期2卷 83-95页

作者： Reza Gholizadeh daisuke Terada Akinobu Shibata Nobuhiro Tsuji Department of Materials Science and Engineering Kyoto UniversityYoshida HonmachiSakyo-kuKyoto606-8501Japan ESISM(Elements Strategy Initiative for Structural Materials) Kyoto UniversityYoshida HonmachiSakyo-kuKyoto606-8501Japan Department of Advanced Materials Science and Engineering Chiba Institute of TechnologyTsudanumaNarashino275-0016Japan

Single-phase bcc-ferrite in an interstitial free(IF)steel was deformed to different strains in a wide range from low to high strains(ε=1–7)by torsion under different Zener-Hollomon(Z)*** specimens were rapidly quenched after the torsion to preserve microstructures formed under different deformation *** results showed that during high-Z(low-temperature)deformation,grains were subdivided by geometrically necessary boundaries(GNBs)via the grain subdivision *** to high strains(ε>5)led to the ultrafine lamellar structures(with grain sizes1μm)were realized with decreasing *** significance of the grain subdivision and the thermally activated phenomena on the formation of various microstructures under different deformation conditions is discussed.

关键词： Severe plastic deformation Grain subdivision Ultrafine grains Zener-Hollomon parameter Boundary migration Electron backscattering diffraction(EBSD)

GPGPU-parallelised hybrid finite-discrete element modelling of rock chipping and fragmentation process in mechanical cutting

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Journal of Rock Mechanics and Geotechnical Engineering 2020年第2期12卷 310-325页

作者： Mojtaba Mohammadnejad Sevda Dehkhoda daisuke Fukuda Hongyuan Liu Andrew Chan School of Engineering College of Science and EngineeringUniversity of TasmaniaHobartTAS7001Australia CSIRO Minerals Resources Business UnitQCAT 1 Technology CourtPullenvaleQLD4069Australia Hatch BrisbaneQLD4000Australia Division of Sustainable Resources Engineering Faculty of EngineeringHokkaido UniversityHokkaidoJapan

Mechanical cutting provides one of the most flexible and environmentally friendly excavation *** has attracted numerous efforts to model the rock chipping and fragmentation process,especially using the explicit finite element method(FEM) and bonded particle model(BPM),in order to improve cutting *** study investigates the application of a general-purpose graphic-processing-unit parallelised hybrid finite-discrete element method(FDEM) which enjoys the advantages of both explicit FEM and BPM,in modelling the rock chipping and fragmentation process in the rock scratch test of mechanical rock *** input parameters of FDEM are determined through a calibration procedure of modelling conventional Brazilian tensile and uniaxial compressive tests of limestone,A series of scratch tests with various cutting velocities,cutter rake angles and cutting depths is then modelled using FDEM with calibrated input parameters.A few cycles of cutter/rock interactions,including their engagement and detachment process,are modelled for each case,which is conducted for the first time to the best knowledge of the authors,thanks to the general purpose graphic processing units(GPGPU) *** failure mechanism,cutting force,chipping morphology and effect of various factors on them are discussed on the basis of the modelled ***,it is concluded that GPGPU-parallelised FDEM provides a powerful tool to further study rock cutting and improve cutting efficiencies since it can explicitly capture different fracture mechanisms contributing to the rock chipping as well as chip formation and the separation process in mechanical ***,it is concluded that chipping is mostly owed to the mix-mode Ⅰ-Ⅱ fracture in all cases although mode Ⅱ cracks and mode Ⅰ cracks are the dominant failures in rock cutting with shallow and deep cutting depths,*** chip morphology is found to be a function of cutter velocdty,cutting depth and cutter rake angl

关键词： Numerical simulation Finite-discrete element method(FDEM) Rock cutting Chipping Cracking

Relationship between tile exfoliation and moisture content

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Frontiers of Architectural Research 2013年第3期2卷 301-309页

作者： Sadayuki Onmura Shuichi Hokoi daisuke Ogura Department of Science and Engineering Setsunan University Osaka 572-8505 Japan Depertment of Architecture ond Archi-tecturel Engineering Kyoto University Kyoto 606-8501 Jopun

In Japan, tile exfoliation from external walls is a serious problem that must be prevented. In our previous study, a tiled concrete sample was dried at a temperature of 105 ℃ for pre- conditioning. Then, tile exfoLiation occurred. Since this seemed to indicate a relationship between tile exfotiation and moisture content, it was further pursued in this study. First, drying experiments on concrete samples just after tiling were carried out under different ambient air temperatures. The following results were obtained. Tile exfoliation occurs even at the Lower drying temperatures. Tile exfoliation starts at corner tiles （seen in all experiments）. When the average moisture content of the tiled concrete sample becomes Lower than a certain value, tile exfoliation occurs. Next, the experiments were analyzed using a three-dimensional model of simultaneous heat and moisture transport. The calculated moisture content agreed well with the measured results. By comparing the measurement and simulation results, it is considered that the tiles are exfoliated when the moisture content of the mortar on the back side of the tile becomes Lower than a certain value. Therefore, the moisture content can serve as an index for evaluating the occurrence of the tile exfoliation.

关键词： External concretewall Tile exfoliation Drying Moisture content Heat and moisturetransport

Protocol analysis of designers using an interactive evolutionary computation

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Frontiers of Architectural Research 2012年第1期1卷 44-50页

作者： Weixin Huang daisuke Matsushita Junzo Munemoto School of Architecture Tsinghua UniversityBeijing 100084China Department of Architecture Okayama University of ScienceJapan

This paper explores the problem-solving behavior of people in design activities through a protocol analysis of verbal reports on the interior work design process simulated by an interactive evolutionary computation （IEC）. The protocol analysis method was used to explore the ways of thinking of the participants throughout the process. The analysis reveals that different parts of the interior scene have different effects on the evaluations, and people tend to use the same evaluation criteria continuously on several images. This kind of behavior is consistent with that of professional designers in past studies and is revealed applicable to nonprofessionals in the current research.

关键词： Interior color ProbIem-sotving beha-vior Protocol analysis Interactive evotution-ary computation (IEC)

Gastric linitis plastica with autoimmune pancreatitis diagnosed by an endoscopic ultrasonography-guided fine-needle biopsy: A case report

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World Journal of Clinical Cases 2022年第31期10卷 11607-11616页

作者： Ryosuke Sato Kazuyuki Matsumoto Hiromitsu Kanzaki Akihiro Matsumi Kazuya Miyamoto Kosaku Morimoto Hiroyuki Terasawa Yuki Fujii Tatsuhiro Yamazaki daisuke Uchida Koichiro Tsutsumi Shigeru Horiguchi Hironari Kato Gastroenterology and Hepatology Okayama University HospitalOkayama 700-8558Japan

BACKGROUND Gastric linitis plastica(GLP)is a subset of gastric cancer with a poor *** is difficult to obtain a definitive diagnosis by endoscopic mucosal biopsies,and the usefulness of an endoscopic ultrasonography-guided fine-needle biopsy(EUSFNB)for GLP has been recently ***,autoimmune diseases are occasionally known to coexist with malignant tumors as paraneoplastic *** herein report the usefulness of an EUS-FNB for detecting GLP and the possibility of paraneoplastic syndrome coexisting with *** SUMMARY An 81-year-old man was admitted to our hospital for a 1-mo history of epigastric pain that increased after *** laboratory data revealed high levels of serum carbohydrate antigen 19-9 and *** examinations showed giant gastric folds and reddish mucosa;however,no epithelial changes were *** gastric lumen was not distensible by air inflation,suggesting *** tomography showed the thickened gastric wall,the diffuse enlargement of the pancreas,and the peripancreatic rim,which suggested autoimmune pancreatitis(AIP)coexisting with *** the pathological findings of the endoscopic biopsy showed no malignancy,he underwent an EUSFNB and was diagnosed with *** received chemotherapy for unresectable gastric cancer due to peritoneal metastasis,after which both the gastric wall thickening and diffuse enlargement of the pancreas were *** An EUS-FNB for GLP with a negative endoscopic biopsy is useful,and AIP may develop as a paraneoplastic syndrome.

关键词： Endoscopic ultrasound-guided fine needle aspiration Linitis plastica Autoimmune pancreatitis Paraneoplastic syndromes Case report

Formation mechanism of extension fractures induced by excavation of a gallery in soft sedimentary rock,Horonobe area,Northern Japan

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Geoscience Frontiers 2013年第1期4卷 105-111页

作者： Tetsuya Tokiwa Kimikazu Tsusaka Makoto Matsubara Taiki Ishikawa daisuke Ogawa Horonobe Underground Research Unit Japan Atomic Energy AgencyHokkaido 098-3224Japan Geoscience Research Laboratory Kanagawa 242-0014Japan Mitsubishi Materials Techno Corporation Tokyo 102-8205Japan

This paper focuses on the formation mechanism of fractures induced by excavation of a gallery in soft sedimentary rocks in the Horonobe area of Japan. Detailed fracture mapping of the gallery indicates that the fractures consist of both pre-existing shear fractures and excavation damaged zone （EDZ） fractures. EDZ fractures correspond to weak planes associated with bedding planes or transgranular cracks. The EDZ fractures terminate against pre-existing shear fractures. Therefore, even for excavations in soft sedimentary rocks, formation of the EDZ fractures are controlled by pre-existing fractures and earlier weak planes.

关键词： Fracture Excavation damaged zone (EDZ)Weak plane Soft rock Excavation

Side-wall effect of runner casing on performance of Darrieus-type hydro turbine with inlet nozzle for extra-low head utilization

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Science China(Technological Sciences) 2010年第1期53卷 93-99页

作者： Kai SHIMOKAWA Akinori FURUKAWA Kusuo OKUMA daisuke MATSUSHITA Satoshi WATANABE Graduate School of Engineering Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan Department of Mechanical Engineering Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan

A ducted Darrieus-type turbine has been proposed for hydropower utilization of extra-low head less than 2 *** the hydro turbine system,in general,might consist of an intake,runner casing section and a draft tube for higher efficiency operation,it was clarified in previous experiment that there was no need of the side-walls of runner casing section and a draft-tube for keeping the efficiency high in the case of duct with an inlet *** would yield a simplification of the structure of the turbine *** order to reconfirm this result for large-sized turbine with 560 mm×300 mm duct,instead of small-sized one with 400 mm×200 mm duct,the side-wall effect on turbine performance was experimentally investigated for three-or four-bladed *** the present paper,the experimental results are shown with considering flow behaviors in the runner section.

关键词： hydro turbine Darrieus-type runner duct side-wall effect turbine performance

Turbo-pump with Isolated Two Stage Impellers for Future Rocket Engine (Trial to Drive Impellers Independently)

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Journal of Thermal Science 2008年第1期17卷 28-34页

作者： Toshiaki Kanemoto Makoto Shimojyo Ryunosuke Kawashima daisuke Tanaka Akira Inagaki Shin Oba Kyushu Institute of Technology:Sensui 1-1 TobataKitakyushu 804-8550Japan Professor Kyushu Institute of Technology:Sensui 1-1 TobataKitakyushu 804-8550Japan DMW Corporation:Miyoshi 3-27 Mishima 411-8560Japan

为了在 impellers 压制成穴并且做涡轮泵，更长生活， inducer 与主要 impeller 被分开，两 impellers 独立地被驾驶。在 impellers 附近的泵和流动条件的表演试验性地被调查，下列结果被获得。(1 ) 主要 impeller 贡献在 inducer 和主... 详细信息

为了在 impellers 压制成穴并且做涡轮泵，更长生活， inducer 与主要 impeller 被分开，两 impellers 独立地被驾驶。在 impellers 附近的泵和流动条件的表演试验性地被调查，下列结果被获得。(1 ) 主要 impeller 贡献在 inducer 和主要 impeller 之间的流动相互作用。(2 ) 两 impellers 的旋转速度能独立地被控制以便同时总体上压制成穴不仅 impeller，而且在 inducer。

关键词：离心式水泵诱导物涡轮机火箭发动机 NPSH