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Heterogeneous pigeon-inspired optimization

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Science China(Information Sciences) 2019年第7期62卷 64-72页

作者： Hao WANG Zhuxi ZHANG Zhen dai Jun CHEN Xi ZHU Wenbo DU Xianbin cao School of Electronic and Information Engineering Frontier Institute of Science and Technology InnovationBeihang University School of Engineering and Materials Science Queen Mary University of London

Pigeon-inspired optimization(PIO) is a swarm intelligence optimizer inspired by the homing behavior of pigeons. PIO consists of two optimization stages which employ the map and compass operator,and the landmark operator, respectively. In canonical PIO, these two operators treat every bird equally,which deviates from the fact that birds usually act heterogenous roles in nature. In this paper, we propose a new variant of PIO algorithm considering bird heterogeneity — HPIO. Both of the two operators are improved through dividing the birds into hub and non-hub roles. By dividing the birds into two groups, these two groups of birds are respectively assigned with different functions of "exploitation" and "exploration", so that they can closely interact with each other to locate the best promising solution. Extensive experimental studies illustrate that the bird heterogeneity produced by our algorithm can benefit the information exchange between birds so that the proposed PIO variant significantly outperforms the canonical PIO.

关键词： heuristic optimization pigeon-inspired optimization particle heterogeneity network-based topology scale-free network selective-informed learning

Nano-vibration exciter:Hypoxia-inducible factor 1 signaling pathway-mediated extracellular vesicles as bioactive glass substitutes for bone regeneration

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Bioactive Materials 2024年第10期40卷 460-473页

作者： Zetao Wang Qiyuan dai Huitong Luo Xiyuan Han Qi Feng Xiaodong cao School of Materials Science and Engineering South China University of TechnologyGuangzhou510641PR China National Engineering Research Centre for Tissue Restoration and Reconstruction Guangzhou510006PR China Key Laboratory of Biomedical Engineering of Guangdong Province South China University of TechnologyGuangzhou510006PR China Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education South China University of TechnologyGuangzhou510006PR China Zhongshan Institute of Modern Industrial Technology of SCUT ZhongshanGuangdong528437PR China

Bioactive glasses(BG)play a vital role in angiogenesis and osteogenesis through releasing functional ***,the rapid ion release in the early stage will cause excessive accumulation of metal ions,which in turn leads to obvious cytotoxicity,long-term inflammation,and bone repair *** by the vibration exciter,small extracellular vesicles(sEVs)obtained by treating mesenchymal stem cells with copper-doped bioactive glass(CuBG-sEVs),is prepared as a nano-vibration *** nano-vibration exciter can convert the ion signals of CuBG into biochemical factor signals through hypoxia-inducible factor 1(HIF-1)signaling pathway and its activated autophagy,so as to better exert the osteogenic activity of *** results showed that CuBG extracts could significantly improve the enrichment of key miRNAs and increase the yield of CuBG-sEVs by activating HIF-1 signaling pathway and its activated *** experiments showed that CuBG-sEVs are favor to cell recruitment,vascularization and osteogenesis as the enrichment of key *** animal experiments results showed that CuBG-sEVs stimulated angiogenesis mediated by CD31 and promoted bone regeneration by activating signaling pathways related to *** findings underscored the significant potential of sEVs as alternative strategies to better roles of BG.

关键词： Copper-doped bioactive glass Extracellular vesicles HIF-1α Bone regeneration

Effects of acid mine drainage on photochemical and biological degradation of dissolved organic matter in karst river water

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Journal of Environmental Sciences 2024年第1期135卷 26-38页

作者： Linwei Li Xingxing cao Chujie Bu Pan Wu Biao Tian Yongheng dai Yeye Ren College of Resources and Environmental Engineering Guizhou UniversityGuiyang 550025China Key Laboratory of Karst Georesources and Environment Ministry of EducationGuizhou UniversityGuiyang 550025China Guizhou Karst Environmental Ecosystems Observation and Research Station Ministry of EducationGuizhou UniversityGuiyang 550025China

Dissolved organic matter(DOM)can be removed or transformed by photochemical and biological processes,producing the negative effect of transforming organic carbon into inorganic carbon,which plays a vital role in the karst carbon ***,acid mine drainage(AMD)will affect this process,so the degradation of DOM in karst river water(KRW)needs to be studied in this *** this study,to reveal the evolution processes of DOM under photochemical and biological conditions in AMD-impacted KRW,AMD and KRW were mixed in different ratios under conditions of visible light irradiation(VL),biodegradation(BD),ultraviolet irradiation(UV)and ultraviolet irradiation+biodegradation(UV+BD).The average DOC concentrations in samples after mixing AMD and KRW in different proportions decreased significantly(by 23%)in UV+BD,which was 1.2–1.4 times higher than under the other conditions and would lead to a significant release of inorganic *** analysis of the fluorescence parameters via parallel factor analysis(PARAFAC)revealed that the DOM fluorescence components in AMD comprised mainly protein-like substances derived from autochthonous components,while the DOM fluorescence components in KRW were mainly humic-like substances with both autochthonous and allochthonous ***,AMD could promote both the photochemical and biological degradation of DOM in karst receiving streams,resulting in the conversion of DOC to inorganic *** results showed that the synergistic effects of UV+BD and AMD accelerated the degradation of DOM and the release of inorganic carbon in KRW,thus affecting the stability of the karst carbon cycle.

关键词： Acid mine drainage Dissolved organic matter Karst river water Photochemical degradation Biological degradation

The Optimal Tenement Allocation for Reducing Traffic Burden

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Journal of the Operations Research Society of China 2016年第2期4卷 233-242页

作者： Ke-Lin Luo yin-Feng Xu Yong-Feng cao School of Management Xi’an Jiaotong UniversityXi’an 710049China State Key Lab for Manufacturing System Engineering Xi’an 710049China

For reducing traffic jams without widening streets,we come up with a tenement rearrangement *** this paper,we study a tenement allocation model which includes two types of tenants,i.e.,typical tenants and special tenants who owned houses by *** optimal allocation is that total transportation cost is minimized without undermining tenants’individual housing preference or increasing individual ***,we present a Modified Hungarian Algorithm for the above tenement allocation problem and prove that it can be solved in polynomial ***,computational tests show that this algorithm has a good performance.

关键词： Tenement allocation Transport fee Traffic burden Modified Hungarian Algorithm

Hybrid data-driven and physics-based modeling for viscosity prediction of ionic liquids

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Green Energy & Environment 2024年第12期9卷 1878-1890页

作者： Jing Fan Zhengxing dai Jian cao Liwen Mu Xiaoyan Ji Xiaohua Lu State Key Laboratory of Materials-Oriented and Chemical Engineering Nanjing Tech UniversityNanjing211816China Energy Engineering Division of Energy ScienceLulea University of TechnologyLulea97187Sweden

Viscosity is one of the most important fundamental properties of ***,accurate acquisition of viscosity for ionic liquids(ILs)remains a critical *** this study,an approach integrating prior physical knowledge into the machine learning(ML)model was proposed to predict the viscosity *** method was based on 16 quantum chemical descriptors determined from the first principles calculations and used as the input of the ML models to represent the size,structure,and interactions of the *** strategies based on the residuals of the COSMO-RS model were created as the output of ML,where the strategy directly using experimental data was also studied for *** performance of six ML algorithms was compared in all strategies,and the CatBoost model was identified as the optimal *** strategies employing the relative deviations were superior to that using the absolute deviation,and the relative ratio revealed the systematic prediction error of the COSMO-RS *** CatBoost model based on the relative ratio achieved the highest prediction accuracy on the test set(R^(2)=0.9999,MAE=0.0325),reducing the average absolute relative deviation(AARD)in modeling from 52.45% to 1.54%.Features importance analysis indicated the average energy correction,solvation-free energy,and polarity moment were the key influencing the systematic deviation.

关键词： Viscosity Fundamental property Ionic liquids COSMO-RS Machine learning

Nanocrystalline Ni(OH)_2 Preparation by Electrolysis in an Aqueous Solution of Nickel Nitrate

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Chemical Research in Chinese Universities 2002年第3期18卷 334-336页

作者： ZHANG Heng bin LI Xue yin cao Xue jing LI Shu jia College of Chemistry Jilin UniversityChangchun 130023P.R.China

Nanocrystalline Ni(OH) 2 was prepared by cathode deposition in an aqueous solution of nickel nitrate. The structure and the morphology were characterized by means of XRD and TEM. The electrode performances were exami... 详细信息

关键词： Nanocrystal Nickel hydroxide Electrolysis

Optimization design and residual thermal stress analysis of PDC functionally graded materials

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第8期7卷 1318-1323页

作者： cao Pin-lu LIU Bao-chang yin Kun ZHANG Zu-pei College of Constructzon Engineering Jilin University Changchun 130026 China Key Laboratory of Geo-exploration Instrumentation Ministry of Education Changchun 130026 China

The distribution of thermal stresses in functionally graded polycrystalline diamond compact (PDC) and in single coating of PDC are analyzed respectively by thermo-mechanical finite element analysis (FEA). It is shown that they each have a remarkable stress concentration at the edge of the interfaces. The diamond coatings usually suffer premature failure because of spallation, distortion or defects such as cracks near the interface due to these excessive residual stresses. Results showed that the axial tensile stress in FGM coating is reduced from 840 MPa to 229 MPa compared with single coating, and that the shear stress is reduced from 671 MPa to 471 MPa. Therefore, the single coating is more prone to spallation and cracking than the FGM coating. The effects of the volume compositional distribution factor (n) and the number of the graded layers (L) on the thermal stresses in FGM coating are also discussed respectively. Modelling results showed that the optimum value of the compositional distribution factor is 1.2, and that the best number of the graded layers is 6.

关键词： Functionally graded materials (FGM) Optimum design Polycrystalline diamond compact (PDC) Residual thermal stress Finite element method (FEM)

Phospholipid membrane-decorated deep-penetrated nanocatalase relieve tumor hypoxia to enhance chemo-photodynamic therapy

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Acta Pharmaceutica Sinica B 2020年第11期10卷 2246-2257页

作者： Junjing yin Haiqiang cao Hong Wang Kaoxiang Sun Yaping Li Zhiwen Zhang School of Pharmacy Yantai UniversityYantai 264005China State Key Laboratory of Drug Research&Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Yantai Key Laboratory of Nanomedicine&Advanced Preparations Yantai Institute of Materia MedicaYantai 264000China

Hypoxia is a serious impediment to current treatments of many malignant ***,an antioxidant enzyme,is capable of decomposing endogenous hydrogen peroxide(H2O2)into oxygen for tumor reoxygenation,but suffered from in vivo instability and limited delivery to deep interior hypoxic regions in ***,a deep-penetrated nanocatalase-loading DiIC18(5,DiD)and soravtansine(Cat@PDS)were provided by coating catalase nanoparticles with PEGylated phospholipids membrane,stimulating the structure and function of erythrocytes to relieve tumor hypoxia for enhanced chemophotodynamic *** intravenous administration,Cat@PDS preferentially accumulated at tumor sites,flexibly penetrated into the interior regions of tumor mass and remarkably relieved the hypoxic status in ***,the Cat@PDS+laser treatment produced striking inhibition of tumor growth and resulted in a 97.2%suppression of lung ***,the phospholipids membrane-coated nanocatalase system represents an encouraging nanoplatform to relieve tumor hypoxia and synergize the chemophotodynamic cancer therapy.

关键词： Photodynamic therapy Tumor hypoxia Catalase Tumor penetration Drug delivery Nanoparticle Tumor targeting Cancer metastasis Cancer therapy

Synthesis of graphene quantum dots for their supramolecular polymorphic architectures

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Nano Research 2021年第4期14卷 1228-1231页

作者： Weifeng Chen Guo Lv Qiyun Zhou Jialu Shen Jie cao Xiang Liu Zhongxu dai Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials College of Materials and Chemical EngineeringChina Three Gorges UniversityYichang 443002China

How to regulate the supramolecular structures in the assembly of graphene quantum dots(GQDs)is still a great challenge to be ***,the GQDs of 1-3 layers with high quality are synthesized from the new precursor m-trihydroxybenzene in a green *** importantly,a strategy for designing the supramolecular structures of GQDs is demonstrated,and the novel supramolecular morphologies of GQDs have been constructed for the first ***,the supramolecular morphologies of GQDs can be well controlled by regulating the preparation conditions,and the formation mechanism of the branch-like supramolecular structure has been explained by the the diffusion-limited aggregation(DLA)*** work not only develops a new precoursor to synthesize GQDs,but also opens up an effective route toform the polymorphic supermolecules,thus greatly facilitating their potential applications.

关键词： graphene quantum dots supermolecule m-trihydroxybenzene synthesis the diffusion-limited aggregation