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On the behaviour characterization of metallic cellular materials under impact loading

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Acta Mechanica Sinica 2010年第6期26卷 837-846页

作者： dai-ning fang Yu-Long Li Han Zhao College of Engineering Peking University 100871 BeijingChina School of Aeronautics Northwestern Polytechnical University 710072 Xi'anChina Laboratoire de Mecanique et Technologie ENS-Cachan/CNRS-UMR8535/Universite Pierre and Marie Curie61avenue du president Wilson 94235 Cachan CedexFrance

This paper reviews the common mechanical features of the metallic cellular material under impact loading as well as the characterization methods of such behaviours. The main focus is on the innovations of various testing methods at impact loading *** aspects were discussed in details.（1） The use of soft nylon Hopkinson/Kolsky bar for an enhanced measuring accuracy in order to assess if there is a strength enhancement or not for this class of cellular materials under moderate impact loading;（2） The use of digital image correlations to determine the strain fields during the tests to confirm the existence of a pseudo-shock wave propagation inside the cellular material under high speed impact：（3） The use of new combined shear compression device to determine the loading envelop of cellular materials under impact multiaxial loadings.

关键词： Foam Honeycomb Lattice Hopkinson bar Rate sensitivity

Mechanics of advanced fiber reinforced lattice composites

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Acta Mechanica Sinica 2010年第6期26卷 825-835页

作者： Hua-Lin Fan Tao Zeng dai-ning fang Wei Yang College of Mechanics and Materials Hohai University Nanjing 210098China Key Laboratory for Advanced Building Materials of Sichuan Province Southwest University of Science and Technology Mianyang 621010China College of Civil Engineering and Architecture Harbin University of Science and TechnologyHarbin 150080China College of Engineering Peking University Beijing 100871China University Office Zhejiang University Hangzhou 310058China

Fiber reinforced lattice composites are lightweight attractive due to their high specific strength and specific *** the past 10 years,researchers developed three-dimensional（3D） lattice trusses and two-dimensional （2D） lattice grids by various methods including interlacing, weaving,interlocking,filament winding and molding hot- *** lattice composites have been applied in the fields of radar cross-section reduction,explosive absorption and heat-resistance. In this paper,topologies of the lattice composites, their manufacturing routes,as well as their mechanical and multifunctional applications,were surveyed.

关键词： Lattice composites Mechanical behaviors Fabrication Multifunction

Properties and appropriate conditions of stress reduction factor and thermal shock resistance parameters for ceramics

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Applied Mathematics and Mechanics(English Edition) 2012年第11期33卷 1351-1360页

作者：李卫国成天宝张如炳方岱宁 Department of Engineering Mechanics College of Resources and Environmental ScienceChongqing University State Key Laboratory for Turbulence and Complex Systems College of EngineeringPeking University

Through introducing the analytical problem of the plate with convection into the solution of the transient heat conduction thermal stress field model of the elastic plate, the stress reduction factor is presented explicitly in its dimensionless form. A new stress reduction factor is introduced for the purpose of comparison. The proper- ties and appropriate conditions of the stress reduction factor, the first and second ther- mal shock resistance （TSR） parameters for the high and low Biot numbers, respectively, and the approximation formulas for the intermediate Blot number-interval are discussed. To investigate the TSR of ceramics more accurately, it is recommended to combine the heat transfer theory with the theory of thermoelasticity or fracture mechanics or use a numerical method. The critical rupture temperature difference and the critical rup- ture dimensionless time can be used to characterize the TSR of ceramics intuitively and legibly.

关键词： stress reduction factor thermal shock resistance (TSR) parameter ceram-ics Biot number Fourier number

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办公建筑能耗数据异常检测

建筑热能通风空调 2020年第10期39卷 79-83,96页

作者：戴宁芳谭洪卫同济大学绿色建筑及新能源研究中心同济大学机械与能源工程学院联合国环境规划署-同济大学环境与可持续发展学院

本文提出了一套公共建筑能耗异常检测框架,将异常能耗分为数据传输异常和运行异常。对数据传输异常采用模式识别型算法,提高数据环境质量。根据建筑能耗特征对运行异常提出不同的算法组合。办公建筑能耗数据结果表明,在异常占比达到5%时... 详细信息

本文提出了一套公共建筑能耗异常检测框架,将异常能耗分为数据传输异常和运行异常。对数据传输异常采用模式识别型算法,提高数据环境质量。根据建筑能耗特征对运行异常提出不同的算法组合。办公建筑能耗数据结果表明,在异常占比达到5%时,异常检测结果的正确率在85%以上,错误率在4%以下。

关键词：异常检测 K-means LOF 箱线图

Characteristics of gut microbiota dysbiosis in patients with colorectal polyps

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 13-21页

作者： Xian-Rong Wu Xiao-Hong He Yong-fang Xie School of Life Health Information Science and Engineering Chongqing Post and Communications UniversityChongqing 400065China

This editorial,inspired by a recent study published in the World Journal of Gastrointestinal Oncology,covers the research findings on microbiota changes in various *** recurrent colorectal polyps,the abundances of Klebsiella,Parvimonas,and Clostridium increase,while those of Bifidobacterium and Lactoba-cillus *** dysbiosis may promote the formation and recurrence of *** microbial changes have also been observed in colorectal cancer,inflammatory bowel disease,autism spectrum disorder,and metabolic syndrome,indicating the role of increased pathogens and decreased probiotics in these *** the gut microbiota,particularly by increasing probiotic levels,may help prevent polyp recurrence and promote gut *** microbial intervention strategy holds promise as an adjunctive treatment for patients with colorectal polyps.

关键词： Recurrent colorectal polyps Gut microbiota dysbiosis Klebsiella Probiotics Intestinal inflammation Microbial intervention strategy

Insights into multisource sludge distributed in the Yangtze River basin, China: Characteristics,correlation, treatment and disposal

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Journal of Environmental Sciences 2023年第4期126卷 321-332页

作者： Yiqun Guo Hui Gong Wenjing Shi ning fang Yaqin Tan Weiqi Zhou Jialiang Huang Lingling dai Xiaohu dai Yali Guo State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shanghai Investigation Design&Research Institute Co.LtdShanghai 200050China YANGTZE Eco-Environment Engineering Research Center(Shanghai) China Three Gorges CorporationShanghai 200050China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China

Sludge is the by-product of wastewater treatment process. Multisource sludge can be defined as sludge from different sources. Based on the sludge properties of five typical cities in the Yangtze River basin, including Jiujiang, Wuhu, Lu’an, Zhenjiang and Wuhan, this study investigated and summarized the characteristic variations and distribution differences of multiple indicators and substances from municipal sludge, dredged sludge, and river and lake sediments. The results demonstrated pH of multisource sludge was relatively stable in the neutral range. Organic matter and water content among municipal sludge were high and varied considerably between different wastewater treatment plants. Dredged sludge had an obviously higher sand content and wider particle distribution, which could be considered for graded utilization depending on its size. The nutrients composition of river and lake sediments was usually stable and special, with lower nitrogen and phosphorus content but higher potassium levels. The sources of heavy metals and persistent organic pollutants in multisource sludge were correlated, generally much higher among municipal sludge than dredged sludge and river and lake sediments, which were the most important limitation for final land utilization. Despite various properties of multisource sludge, the final fate and destination have some overall similarities, which need to be supplemented and improved by standards and laws. The study provided a preliminary analysis of suitable technical routes for municipal sludge, dredged sludge, river and lake sediments based on their different characteristics respectively, which was of great significance for multisource sludge co-treatment and disposal in the future of China.

关键词： Multisource sludge Basic characteristics Potential correlation Treatment and disposal Heavy metals Persistent organic pollutants

Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor-and Cygb-associated signaling pathways

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Neural Regeneration Research 2025年第9期20卷 2706-2726页

作者： Biao Xiao Chaoyang Chu Zhicheng Lin Tianyuan fang Yuyu Zhou Chuxia Zhang Jianghui Shan Shiyu Chen Liping Li Department of Physiology and Pharmacology Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina ningbo Key Laboratory of Behavioral Neuroscience Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Key Laboratory of Addiction Research of Zhejiang Province NingboZhejiang ProvinceChina

A reduction in adult neurogenesis is associated with behavioral abnormalities in patients with Alzheimer's ***,enhancing adult neurogenesis represents a promising therapeutic approach for mitigating disease symptoms and ***,nonpharmacological interventions aimed at inducing adult neurogenesis are currently *** individual non-pharmacological interventions,such as aerobic exercise,acousto-optic stimulation,and olfactory stimulation,have shown limited capacity to improve neurogenesis and cognitive function in patients with Alzheimer's disease,the therapeutic effect of a strategy that combines these interventions has not been fully *** this study,we observed an age-dependent decrease in adult neurogenesis and a concurrent increase in amyloid-beta accumulation in the hippocampus of amyloid precursor protein/presenilin 1 mice aged 2-8 *** deposition became evident at 4 months,while neurogenesis declined by 6 months,further deteriorating as the disease ***,following a 4-week multifactor stimulation protocol,which encompassed treadmill running(46 min/d,10 m/min,6 days per week),40 Hz acousto-optic stimulation(1 hour/day,6 days/week),and olfactory stimulation(1 hour/day,6 days/week),we found a significant increase in the number of newborn cells(5'-bromo-2'-deoxyuridine-positive cells),immature neurons(doublecortin-positive cells),newborn immature neurons(5'-bromo-2'-deoxyuridine-positive/doublecortin-positive cells),and newborn astrocytes(5'-bromo-2'-deoxyuridine-positive/glial fibrillary acidic protein-positive cells).Additionally,the amyloid-beta load in the hippocampus *** findings suggest that multifactor stimulation can enhance adult hippocampal neurogenesis and mitigate amyloid-beta neuropathology in amyloid precursor protein/presenilin 1 ***,cognitive abilities were improved,and depressive symptoms were alleviated in amyloid precursor protein/presenilin 1 mice

关键词： acousto-optic stimulation adult neurogenesis Alzheimer's disease amyloid precursor protein/presenilin 1 mice amyloid-beta deposition brain cell apoptosis cognitive impairment depression-like behavior involuntary treadmill exercise olfactory stimulation serum metabolites

Prospects of elafibranor in treating alcohol-associated liver diseases

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World Journal of Gastroenterology 2025年第2期31卷 132-137页

作者： Wei-Tong Cui Hua-Ru Xue Dian-fang Wei Xiao-Yu Feng Kai Wang School of Basic Medicine Qilu Medical UniversityZibo 255300Shandong ProvinceChina School of Medical Imaging Qilu Medical UniversityZibo 255300Shandong ProvinceChina

Alcohol-related liver disease(ALD),which is induced by excessive alcohol con-sumption,is a leading cause of liver-related morbidity and *** pa-tients exhibit a spectrum of liver injuries,including hepatic steatosis,inflam-mation,and fibrosis,similar to symptoms of nonalcohol-associated liver diseases such as primary biliary cholangitis,metabolic dysfunction-associated steatotic liver disease,and nonalcoholic *** has been approved for the treatment of primary biliary cholangitis and has been shown to improve symptoms in both animal models and in vitro cell models of metabolic dysfunc-tion-associated steatotic liver disease and nonalcoholic ***,the efficacy of elafibranor in treating ALD remains *** this article,we comment on the recent publication by Koizumi et al that evaluated the effects of elafibranor on liver fibrosis and gut barrier function in an ALD mouse *** findings indicate the potential of elafibranor for ALD treatment,but further experimental investigations and clinical trials are warranted.

关键词： Elafibranor Alcohol-associated liver diseases Peroxisome proliferator-activated receptor Lipid Apoptosis Steatosis Inflammation Fibrosis

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou Ru Ye Liyan Zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao fang Junfan fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission