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寄生虫与医学昆虫学报 2022年第2期29卷 98-110页

作者：琚俊科李栋龚正达高子厚连宏宇权寿瑛段兴德冯锡光洪梅张丽云大理大学公共卫生学院云南大理671000 云南省地方病防治所云南大理671000 云南省寄生虫病防治所云南普洱665099 安阳市第五人民医院河南安阳455000 北大医疗潞安医院山西襄垣046204

云南西南部山区广泛存在家鼠型鼠疫疫源地,为了解该区域山地农耕区小兽类物种多样性空间分布格局、特征及其与寄生蚤之间关系,本文以滇西南的耿马、临沧、陇川、龙陵、盈江、梁河、腾冲和云龙8县(市)为调查研究的空间范围,对各县(市)多... 详细信息

云南西南部山区广泛存在家鼠型鼠疫疫源地,为了解该区域山地农耕区小兽类物种多样性空间分布格局、特征及其与寄生蚤之间关系,本文以滇西南的耿马、临沧、陇川、龙陵、盈江、梁河、腾冲和云龙8县(市)为调查研究的空间范围,对各县(市)多个乡镇的农耕区进行小兽及寄生蚤类的调查取样,所获小兽和蚤类数据进行统计学处理后,就当地小兽物种多样性空间分布格局、特征及其与蚤类之间的关系进行分析和探讨。结果显示:(1)共捕获小兽7科19属35种共2890只,采获小兽体表寄生蚤6科16属27种共2840只。两者科、属和种不同阶元丰富度之间对比后可以看出,宿主小兽科、属和种的丰富度均较寄生蚤类的丰富度高一些,他们之间的差距并随着科、属至种的分类阶元变小而呈现逐步增大的趋势。(2)由于地理位置和气候环境条件的差异,各县(市)样区小兽的物种丰富度明显不同,其中,最高为临沧24种,其次腾冲和云龙各20种,最低为耿马仅8种。此外,各县(市)小兽的优势种及其相对多度也不尽相同,其中,黄胸鼠是耿马(69.51%)、陇川(52.18%)、龙陵(43.36%)和梁河(34.03%)的优势种;斑胸鼠(53.21%)、滇绒鼠(20.48%)、锡金小鼠(23.10%)、屋顶鼠(30.29%)分别为盈江、临沧、腾冲和云龙数量上的优势种;而其余物种的多度相对较少或很少。(3)小兽物种丰富度(γ多样性)总体的变化趋势呈现了随海拔的升高而逐步降低的分布特征。(4)小兽的Cody指数(β多样性)沿海拔梯度的增加呈现逐步升高的趋势,最高点位于海拔C~D带(2000~2500 m)。而Sorenson指数随海拔增高呈逐步降低的分布格局,最高点位于A~B带(800~1500 m)。它显示了高寒层(海拔2500 m以上)暖温带气候类型农耕区小兽群落、物种和区系的组成发生了较大变化。(5)小兽物种丰富度和物种多样性(α多样性)以临沧、腾冲和云龙3县市较高,多样性指数分别为2.5530、2.5345和2.3770;均匀度指数分别为0.8033、0.8460和0.7935,而生态优势度指数都相对较低,分别为0.1061、0.1041和0.1445,优势种多度分别为20.48、23.10和30.29;与此相反,耿马县的物种丰富度最低、物种多样性指数(0.8879)和均匀度指数(0.4270)亦最低,而生态优势度(0.5369)和优势种的多度(69.51)最高。相关分析显示:小兽的物种多样性与物种丰富度之间呈极显著正相关,而与生态优势度和优势种多度之间呈极显著负相关。表明该区域小兽优势种的组成及其多度的空间分布特征主导了小兽物种多样性的变化趋势。(6)聚类分析结果显示:小兽沿海拔梯度的分布可分为3个主要类型,低海拔、中海拔和高海拔区,他们沿海拔梯度的垂直分布特征与当地不同气温层农耕区的构成相一致。反映了海拔高度、气候环境条件和耕作区类型对小兽物种、群落的组成及其空间分布格局具有重要影响。(7)小兽物种丰富度随海拔升高呈逐步降低的分布格局,而寄生蚤物种丰富度随海拔的升高呈先增高后降低的分布格局,但两者的物种丰富度都随着海拔增高和气候环境变化,总体呈现为逐步下降的趋势。8个县(市)样区小兽与寄生蚤类多样性之间关系的相关分析显示:小兽的物种多样性、物种丰富度、均匀度和生态优势度与蚤类丰富度之间极显著相关,说明当地小兽与寄生蚤之间明显存在着协同进化与共存的关系;但是,小兽与寄生蚤的物种多样性和生态优势度之间的关系并不十分密切,也反映出两者物种多样性和优势种多度的空间分布格局及其特征之间存在一定的差异。

关键词：小型兽类物种多样性生态优势度物种多度空间分布蚤类相关分析家鼠鼠疫疫源地滇西南

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Phase Ⅱ study of R-CVP followed by rituximab maintenance therapy for patients with advanced marginal zone lymphoma:consortium for improving survival of lymphoma(CISL)study

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Cancer Communications 2019年第1期39卷 526-535页

作者： Sung Yong Oh Won Seog Kim Jin Seok Kim Seok Jin Kim Dok Hyun Yoon Deok-Hwan Yang Won Sik Lee Hyo Jung Kim Ho-young Yhim Seong Hyun Jeong Jong Ho Won Suee Lee Jee Hyun Kong Sung-Nam Lim Jun Ho Ji Kyung A.kwon Gyeong-Won Lee Jae Hoon Lee Ho Sup Lee Ho-Jin Shin Cheolwon Suh Department of Internal Medicine Dong-A University HospitalBusan 49201Republic of Korea Department of Medicine Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351Republic of Korea Division of Hematology Department of Internal MedicineYonsei University College of MedicineSeoul 03722Republic of Korea Department of Oncology Asan Medical CenterUniversity of Ulsan College of MedicineSongpa-guSeoul 05505Republic of Korea Department of Hematology-Oncology Chonnam National University Hwasun HospitalHwasun 58128Republic of Korea Department of Hematology Busan Paik HospitalInje University College of MedicineBusan 04511Republic of Korea Department of Internal Medicine Hallym University Sacred Heart HospitalHallym University College of MedicineAnyang 14068Republic of Korea Department of Internal Medicine Chonbuk National University HospitalJeonju 54907Republic of Korea Department of Hematology-Oncology Ajou University School of MedicineSuwon 16499Republic of Korea Department of Internal Medicine Soonchunhyang University Seoul HospitalSoonchunhyang University College of MedicineSeoul 04401Republic of Korea Division of Hematology-Oncology Department of Internal MedicineWonju Severance Christian HospitalYonsei University College of MedicineWonju 26426Republic of Korea Department of Internal Medicine Haeundae Paik HospitalInje University College of MedicineBusan 48108Republic of Korea Division of Hematology and Oncology Department of Internal MedicineSamsung Changwon HospitalSungkyunkwan University School of MedicineChangwon 51353Republic of Korea Division of Hematology-Oncology Department of Internal MedicineDongnam Institute of Radiological and Medical SciencesBusan 46033Republic of Korea Division of Hematology-Oncology Department of Internal MedicineGyeongsang National University HospitalGyeongsang National University College of MedicineJinju 52727Republic of Korea Department of Internal Medicine Gachon University Gil Medical CenterIncheon 21565Republic of

Background:The response rate and survival improvement for rituximab,a CD20-targeting monoclonal antibody,have been demonstrated in marginal zone lymphoma(MZL)as monotherapy and in combination with chemotherapeutic regimens,yet relapses still occur despite treatment ***,extending the period of remission in MZL patients remains an essential *** multicenter,single-arm,open-label phase II study evaluated the survival efficacy of 2 years of rituximab-maintenance therapy in patients with stage III-IV CD20-positive MZL who had responded to first-line R-CVP(rituximab,cyclophosphamide,vincristine,and prednisolone).The objective of this study was to determine whether rituximab maintenance following R-CVP warrants further ***:Prior to rituximab-maintenance therapy,patients received 6-8 cycles of first-line R-CVP therapy for stage III-IV ***(375 mg/m^(2)),cyclophosphamide(750 mg/m^(2)),and vincristine(1.4 mg/m^(2);maximum 2 mg)were administered via an intravenous infusion on day 1 of each 3-week cycle,while oral prednisolone(100 mg)was given on days 1-5 of each 3-week *** patients who achieved complete response(CR),partial response(PR),or stable disease(SD)to R-CVP treatment,were prescribed rituximab-maintenance therapy which was administered intravenously at a dose of 375 mg/m^(2) every 8 weeks for up to 12 *** primary endpoint was progression-free survival(PFS).Secondary endpoints were overall survival(OS)and treatment ***:47 patients were enrolled,of whom,45(96%)received rituximab-maintenance ***(33%)patients had nodal *** R-CVP first-line therapy,20(44%),22(49%),and 3(7%)patients achieved CR,PR,and SD,*** a median follow-up of 38.2 months,their observed 3-year PFS rate was 81%.During the rituximab-maintenance,6 PR and 1 SD patients achieved CR following the administration of *** LDH and the presence of B symptoms were found to be significant prognostic fac

关键词： Marginal zone Lymphoma Advanced stage Rituximab Cyclophosphamide Vincristine Maintenance Multicenter Open label Survival

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国人外耳道上棘的初步观察

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解剖学报 1963年第1期 87-89页

作者：张生贵黎屏周朱公任李冠城潘铭紫(指导) 第四军医大学人体解剖学教研室江西南昌医学院齐齐哈尔医学院南京铁道医学院

外耳道上棘是耳科临床上在施行与乳突和鼓窦有关手术时一重要骨性标志,它的显著与否对手术进行的顺利起着一定的作用。本文对国人外耳道上棘的性别和年龄特征作了观察。本文观察了442侧国人颅骨的外耳道上棘,其中256侧属于成年男性,142... 详细信息

外耳道上棘是耳科临床上在施行与乳突和鼓窦有关手术时一重要骨性标志,它的显著与否对手术进行的顺利起着一定的作用。本文对国人外耳道上棘的性别和年龄特征作了观察。本文观察了442侧国人颅骨的外耳道上棘,其中256侧属于成年男性,142侧属于成年女性,44侧属于未成年的男女。将外耳道上棘出现的不同情况分为最显、显著、微显、不显四型。观察结果,最显和显著两型都是成年男性(17.97%和41.80%)高于成年女性(5.63%和20.42%),而微显型和不显型则适得其反。未成年男女的外耳道上棘都是发育较差,不显型有52.29%、微显型40.91%、显著型只有6.82%,无最显型。经过统计处理证明外耳道上棘的性别和年龄差别均显著。侧差均不显著。

关键词：外耳道性别耳科道上棘成年女性国人

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SU(n) MULTIPLETS AND young DIAGRAMS

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Chinese Physics C 2014年第9期38卷 507-507页

作者： K.A.Olive K.Agashe C.Amsler M.Antonelli J.-F.Arguin D.M.Asner H.Baer H.R.Band R.M.Barnett T.Basaglia C.W.Bauer J.J.Beatty V.I.Belousov J.Beringer G.Bernardi S.Bethke H.Bichsel O.Biebe E.Blucher S.Blusk G.Brooijmans O.Buchmueller V.Burkert M.A.Bychkov R.N.Cahn M.Carena A.Ceccucci A.Cerr D.Chakraborty M.-C.Chen R.S.Chivukula K.Copic G.Cowan O.Dahl G.D'Ambrosio T.Damour D.de Florian A.de Gouvea T.DeGrand P.de Jong G.Dissertor B.A.Dobrescu M.Doser M.Drees H.K.Dreiner D.A.Edwards S.Eidelman J.Erler V.V.Ezhela W.Fetscher B.D.Fields B.Foster A.Freitas T.K.Gaisser H.Gallagher L.Garren H.-J.Gerber G.Gerbier T.Gershon T.Gherghetta S.Golwala M.Goodman C.Grab A.V.Gritsan C.Grojean D.E.Groom M.Grnewald A.Gurtu T.Gutsche H.E.Haber K.Hagiwara C.Hanhart S.Hashimoto Y.Hayato K.G.Hayes M.Heffner B.Heltsley J.J.Hernandez-Rey K.Hikasa A.Hocker J.Holder A.Holtkamp J.Huston J.D.Jackson K.F.Johnson T.Junk M.Kado D.Karlen U.F.Katz S.R.Klein E.Klempt R.V.Kowalewski F.Krauss M.Kreps B.Krusche Yu.V.Kuyanov Y.kwon O.Lahav J.Laiho P.Langacker A.Liddle Z.Ligeti C.-J.Lin T.M.Liss L.Littenberg K.S.Lugovsky S.B.Lugovsky F.Maltoni T.Mannel A.V.Manohar W.J.Marciano A.D.Martin A.Masoni J.Matthews D.Milstead P.Molaro K.Monig F.Moortgat M.J.Mortonson H.Murayama K.Nakamura M.Narain P.Nason S.Navas M.Neubert P.Nevski Y.Nir L.Pape J.Parsons C.Patrignani J.A.Peacock M.Pennington S.T.Petcov Kavli IPMU A.Piepke A.Pomarol A.Quadt S.Raby J.Rademacker G.Raffel B.N.Ratcliff P.Richardson A.Ringwald S.Roesler S.Rolli A.Romaniouk L.J.Rosenberg J L.Rosner G.Rybka C.T.Sachrajda Y.Sakai G.P.Salam S.Sarkar F.Sauli O.Schneider K.Scholberg D.Scott V.Sharma S.R.Sharpe M.Silari T.Sjostrand P.Skands J.G.Smith G.F.Smoot S.Spanier H.Spieler C.Spiering A.Stahl T.Stanev S.L.Stone T.Sumiyoshi M.J.Syphers F.Takahashi M.Tanabashi J.Terning L.Tiator M.Titov N.P.Tkachenko N.A.Tornqvist D.Tovey G.Valencia G.Venanzoni M.G.Vincter P.Vogel A.Vogt S.P.Wakely W.Walkowiak C.W.Walter D.R.Ward G.Weiglein D.H.Weinberg E.J.Weinberg M.White L.R.Wiencke C.G.Wohl L.Wolfenstein J.Womersley C.L. University of Minnesota School of Physics and Astronomy116 Church St.S.E.MinneapolisMN 55455USA University of Maryland Department of PhysicsCollege ParkMD 20742-4111USA Albert Einstein Center for Fundamental Physics Universitat BernCH-3012 BernSwitzerland Lab.Nazionali di Frascati dell'INFN CP 13via E.Fermi40I-00044 Frascati(Roma)Italy Departement de physique Universite de MontrealC.P.6128succ.centre-villeMontreal(Quebec) H3C 3J7Canada Pacific Northwest National Laboratory 902 Battelle BoulevardRichlandWA 99352USA Department of Physics and Astronomy University of OklahomaNormanOK 73019USA Department of Physics University of WisconsinMadisonWI 53706USA Physics Division Lawrence Berkeley National Laboratory1 Cyclotron RoadBerkeleyCA 94720USA CERN European Organization for Nuclear ResearchCH-1211 Geneve 23Switzerland Department of Physics The Ohio State University191 W.Woodruff Ave.ColumbusOH 43210 COMPAS Group Institute for High Energy PhysicsRU- 142284ProtvinoRussia LPNHE IN2P3-CNRS et Universites de Paris 6 et 7F-75252 ParisFrance Max-Planck-Institute of Physics 80805 MunichGermany Department of Physics University of WashingtonSeattleWA 98195USA Ludwig-Maximilians-Universitat Fakultdt für PhysikSchellingstr.4D-80799 MünchenGermany Enrico Fermi Institute and Department of Physics University of ChicagoChicagoIL 60637-1433USA Department of Physics Syracuse UniversitySyracuseNY13244USA Department of Physics Columbia University538 W.120th StreetNew YorkNY10027 USA High Energy Physics Group Blackett LaboratoryImperial CollegePrince Consort RoadLondon SW7 2AZUK Jefferson Lab 12000 Jefferson Ave.Newport NewsVA 23606USA Department of Physics University of VirginiaPO Box 400714CharlottesvilleVA 22904USA Fermi National Accelerator Laboratory P.O.Box 500BataviaIL 60510USA Kavli Institute for Cosmological Physics University of ChicagoChicagoIL 60637-1433USA Department of Physics and Astronomy University of SussexFalmerBrighton BN1 9QHUK Department o

Written by C.G. Wohl （LBNL）. This note tells （1） how SU（n） particle multiplets are identified or labeled, （2） how to find the number of particles in a multiplet from its label, （3） how to draw the young diagram for a multiplet, and （4） how to use young diagrams to determine the overall multiplet structure of a composite system, such as a 3-quark or a meson-baryon system.

关键词： SU MULTIPLETS AND young DIAGRAMS than

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