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Journal of Forestry Research 2017年第5期28卷 1007-1018页

作者： Do-Hyun Kim Sung-Jun Na Sea-Hyun Kim Ewane Basil Ewane dae-bong kang Do-Hyung Lee Department of Forest Resources Yeungnam University Department of Forest Genetic Resources National Institute of Forest Science

We estimated the growth volume of artificially reforested Pinus densiflora in a post-fire area on three different contour conditions by comparing and analyzing the vertical and horizontal distributions of below-ground roots on each contour. The main roots at the south-facing slope (SS) developed in a long and straight form, and those on the north-facing slope (NS) in a twisted form. The side roots developed more than the main roots on the Ridge. The depth of taproots decreased in the following order: SS > NS > Ridge. The roots on the SS developed in a pile-form root structure whereas those in the Ridge and NS developed concentrically near the root collar. The amount of root development decreased in the following order: SS > NS > Ridge. The ratio of fine roots from the whole-root development decreased in the following order: Ridge > SS > NS. These results can guide considerations of growth differences according to the planting contour conditions for future establishment of P. densiflora artificial plantations.

关键词： Pinus densiflora Growth characteristics Contour conditions Post-fire plantation Wildfire Restoration Soil depth

Preparation of silver nanoparticles through the reduction of straw-extracted lignin and its antibacterial hydrogel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 504-514页

作者： Lou Zhang Shuo Li Fu Tang Jingkai Zhang Yuetong kang Hean Zhang Lidong Li State Key Laboratory for Advanced Metals and Materials School of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijing 100083China

Silver nanoparticles(Ag NPs)have attracted attention in the field of biomaterials due to their excellent antibacterial ***,the reducing and stabilizing agents used for the chemical reduction of Ag NPs are usually toxic and may cause water *** this work,Ag NPs(31.2 nm in diameter)were prepared using the extract of straw,an agricultural waste,as the reducing and stabilizing *** analysis revealed that the straw extract contained lignin,the structure of which possesses phenolic hydroxyl and methoxy groups that facilitate the reduction of silver salts into Ag *** surfaces of Ag NPs were negatively charged due to the encapsulation of a thin layer of lignin molecules that prevented their *** the prepared Ag NPs were added to the precursor solution of acrylamide,free radical polymerization was triggered without the need for extra heating or light irradiation,resulting in the rapid formation of an Ag NP-polyacrylamide composite *** inhibition zone test proved that the composite hydrogel possessed excellent antibacterial ability due to the presence of Ag *** prepared hydrogel may have potential applications in the fabrication of biomedical materials,such as antibacterial dressings.

关键词： silver nanoparticles hydrogel straw extraction antibacterial

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

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Neural Regeneration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui kang Xuan Cheng Hui Gao Shujia Huo Haiwei Xu Key Lab of Visual Damage and Regeneration&Restoration of Chongqing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased *** lower vertebrates like zebrafish,these cells assume responsibility for spontaneous retinal regeneration,wherein endogenous Müller glia undergo proliferation,transform into Müller glia-derived progenitor cells,and subsequently regenerate the entire retina with restored ***,Müller glia in the mouse and human retina exhibit limited neural reprogramming.Müller glia reprogramming is thus a promising strategy for treating neurodegenerative ocular disorders.Müller glia reprogramming in mice has been accomplished with remarkable success,through various *** in molecular,genetic,epigenetic,morphological,and physiological evaluations have made it easier to document and investigate the Müller glia programming process in ***,there remain issues that hinder improving reprogramming efficiency and ***,understanding the reprogramming mechanism is crucial toward exploring factors that will improve Müller glia reprogramming efficiency,and for developing novel Müller glia reprogramming *** review describes recent progress in relatively successful Müller glia reprogramming *** also provides a basis for developing new Müller glia reprogramming strategies in mice,including epigenetic remodeling,metabolic modulation,immune regulation,chemical small-molecules regulation,extracellular matrix remodeling,and cell-cell fusion,to achieve Müller glia reprogramming in mice.

关键词： cell fusion chemical small-molecules epigenetic extracellular matrix immune metabolic mice Müller glia neurodegenerative diseases reprogramming retina regeneration

The autophagy-lysosome pathway:a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

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Neural Regeneration Research 2025年第1期20卷 139-158页

作者： Fengjuan Jiao Lingyan Meng kang Du Xuezhi Li School of Mental Health Jining Medical UniversityJiningShandong ProvinceChina Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong ProvinceChina

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such asα-synuclein in *** one of the major intracellular degradation pathways,the autophagy-lysosome pathway plays an important role in eliminating these *** evidence has shown that upregulation of the autophagy-lysosome pathway may contribute to the clearance ofα-synuclein aggregates and protect against degeneration of dopaminergic neurons in Parkinson’s ***,multiple genes associated with the pathogenesis of Parkinson’s disease are intimately linked to alterations in the autophagy-lysosome ***,this pathway appears to be a promising therapeutic target for treatment of Parkinson’s *** this review,we briefly introduce the machinery of ***,we provide a description of the effects of Parkinson’s disease–related genes on the autophagy-lysosome ***,we highlight the potential chemical and genetic therapeutic strategies targeting the autophagy–lysosome pathway and their applications in Parkinson’s disease.

关键词： autophagy chemical therapy gene therapy Parkinson’s disease α-synuclein

Characterization of Ceramic Composite-Membranes Prepared by ORMOSIL Coating Sol

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Journal of Rare Earths 2004年第Z2期22卷 136-140页

作者： Goo-dae Kim Tae-bong Kim School of New Materials Science and Engineering Yonsei UniversitySeoul 120-749Korea Division of MaterialsKorea Institute Science and TechnologySeoul 136-791Korea

Sol-gel methods offer many advantages over conventional slip-casting, including the ability to produce ceramic membranes. They are purer, more homogeneous, more reactive and contain a wider variety of compositions. We produced ormosil sol using sol-gel process under different molecular weight of polymer species [polyethylene glycol (PEG) ] in total system [Tetraethyl ortho silicate(TEOS)-polyethylene glycol (PEG)]. The properties of as-prepared ormosil sol such as,viscosity, gelation time were characterized. Also, the ceramic membrane was prepared by dip-coating with synthetic sol and its micro-structure was observed by scanning electron microscopy. The permeability and rejection efficiency of membrane for oil/water emulsion were evaluated as cross-flow apparatus. The ormosil sol coated Membrane is easily formed by steric effect of polymer and it improves flux efficiency because infiltration into porous support decreased. Its flux efficiency is elevated about 200(1/m2·h) compared with colloidal sol coated membrane at point of five minutes from starting test.

关键词： ORMOSIL sol crack Resistance ultra-filter micro-filter

Potential role of tanycyte-derived neurogenesis in Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1599-1612页

作者： Guibo Qi Han Tang Jianian Hu Siying kang Song Qin Department of Anatomy Histologyand EmbryologySchool of Basic Medical SciencesFudan UniversityShanghaiChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan UniversityShanghaiChina

Tanycytes, specialized ependymal cells located in the hypothalamus, play a crucial role in the generation of new neurons that contribute to the neural circuits responsible for regulating the systemic energy balance. The precise coordination of the gene networks controlling neurogenesis in naive and mature tanycytes is essential for maintaining homeostasis in adulthood. However, our understanding of the molecular mechanisms and signaling pathways that govern the proliferation and differentiation of tanycytes into neurons remains limited. This article aims to review the recent advancements in research into the mechanisms and functions of tanycyte-derived neurogenesis. Studies employing lineage-tracing techniques have revealed that the neurogenesis specifically originating from tanycytes in the hypothalamus has a compensatory role in neuronal loss and helps maintain energy homeostasis during metabolic diseases. Intriguingly,metabolic disorders are considered early biomarkers of Alzheimer's disease. Furthermore,the neurogenic potential of tanycytes and the state of newborn neurons derived from tanycytes heavily depend on the maintenance of mild microenvironments, which may be disrupted in Alzheimer's disease due to the impaired blood–brain barrier ***, the specific alterations and regulatory mechanisms governing tanycyte-derived neurogenesis in Alzheimer's disease remain unclear. Accumulating evidence suggests that tanycyte-derived neurogenesis might be impaired in Alzheimer's disease, exacerbating neurodegeneration. Confirming this hypothesis, however, poses a challenge because of the lack of long-term tracing and nucleus-specific analyses of newborn neurons in the hypothalamus of patients with Alzheimer's disease. Further research into the molecular mechanisms underlying tanycyte-derived neurogenesis holds promise for identifying small molecules capable of restoring tanycyte proliferation in neurodegenerative diseases. This line of investigation could pro

关键词： Alzheimer's disease blood–brain barrier ependymoglial cells hypothalamus metabolic diseases neural stem cells neurogenesis neuroinflammatory diseases neurons tanycyte

Evaluation of the performance of a soft X-ray charger for the bipolar charging of nanoparticles

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Particuology 2015年第1期13卷 165-169页

作者： Young Hun Yoon Choonkeun bong dae Seong Kim Department of Integrated Environmental Systems Pyeongtaek University GreenSolus Co. Global Frontier Center for Multiscale Energy Systems Seoul National University

The use of soft X-rays in a neutralizer represents an alternative technique that could replace conventional radioactive sources. In this study, we evaluated the charging characteristics of a soft X-ray aerosol neu- tralizer. In addition, the results from the evaluation of the soft X-ray charger were compared with results obtained using a neutralizer incorporating an 241 Am radioactive source. The tandem differential mobility analyzer technique was used previously to determine the size-dependent positive, negative, and neutral charge fractions of a soft X-ray neutralizer. This technique was used to show that the neutral fractions obtained using the soft X-ray charger agreed well with the predictions of bipolar diffusion charging the- ory, and that the soft X-ray charger could be used as a neutralizer for a scanning mobility particle sizer system.

关键词： Soft X-ray Neutralizer Bipolar charger Nanoparticle TDMA

Study on wear behavior of plasma electrolytic oxidation coatings on aluminum alloy

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Rare Metals 2006年第Z2期25卷 141-145页

作者： kang Suk-bong LEE Jung-Moo Department of Materials Engineering Korean Institute of Machinery & Materials Gyeongnam 641831 Korea

Thick and hard ceramic coatings were fabricated on A356 aluminum alloy by using plasma electrolytic oxidation(PEO) technique. The microstructure and phase composition of the PEO coatings were examined by using SEM and XRD method. It is found that the PEO coatings are mainly composed of crystalline α-Al2O3 and mullite. The dry sliding wear test of PEO coatings were carried out on a ring-on-ring wear machine. Results shows that there is hardly no wear loss of polished PEO coatings while the wear rate of uncoated aluminum alloy is 4.3×10-5 mm3·(N·m)-1 at a speed of 0.52 m·s-1 and a load of 40 N.

关键词： aluminum alloy plasma electrolytic oxidation ceramic coating wear

Rational design and synthesis of hierarchically structured SnO2 microspheres assembled from hollow porous nanoplates as superior anode materials for lithium-ion batteries

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Nano Research 2018年第3期11卷 1301-1312页

作者： Gi dae Park Yun Chan kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seoul 136-713 Republic of Korea

Herein, hierarchically structured SnO2 microspheres are designed and synthesized as an efficient anode material for lithium-ion batteries using hollow SnO2 nanoplates. Three-dimensionally ordered macroporous （3-DOM） SnOx-C microspheres synthesized by spray pyrolysis are transformed into hierarchically structured SnO2 microspheres by a two-step post-treatment process. Sulfidation produces hierarchically structured SnS-SnS2-C microspheres comprising tin sulfide nanoplate and carbon building blocks. A subsequent oxidation process produces SnO2 microspheres from hollow SnO2 nanoplate building blocks, which are formed by Kirkendall diffusion. The discharge capacity of the hierarchically structured SnO2 microspheres at a current density of 5 Ag^-1 for the 600th cycle is 404 mA·h·g^-1. The hierarchically structured SnO2 microspheres have reversible discharge capacities of 609 and 158 mA·h·g^-1 at current densities of 0.5 and 30 Ag^-1, respectively. The ultrafine nanosheets contain empty voids that allow excellent lithium-ion storage performance, even at high current densities.

关键词： Kirkendall diffusion nanoplate tin oxide lithium-ion batter spray pyrolysis

Microstructure comparison of ZK60 alloy under casting,twin roll casting and hot compression

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Transactions of Nonferrous Metals Society of China 2010年第5期20卷 763-768页

作者：王守仁王敏 kang Suk-bong CHO Jae-hyung School of Mechanical Engineering University of Ji'nan School of Materials Science and Engineering Shandong University Korea Institute of Materials Science 66 Sangnam-dongChangwon 641010Korea

The microstructures of ZK60 alloy under conventional direct as-casting (DC),twin roll casting (TRC) and twin roll casting followed by hot compression (TRC-HC) were analyzed by optical morphology (OM),electron backscatter diffraction (EBSD) and X-ray diffraction (XRD).The deformation condition of hot compression is 350 ℃,0.1 s?*** microstructural evolution under TRC-HC deformation followed by annealing at different temperatures and time was *** results show that TRC provides more modified microstructure compared with *** are found in TRC processing;dynamic recrystallization (DRX),shear bands and twins are found in TRC-HC.A short annealing time has little effect on hardness,while during a long time annealing,it is found that low annealing temperatures increase the micro-hardness and high temperature decreases it.

关键词： microstructural evolution anneal dynamic recrystallization static recrystallization twin-roll casting hot compression magnesium alloy ZK60