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A prototype online database-enabled design framework for wind analysis/design of low-rise buildings

Frontiers of Structural and Civil Engineering 2016年第1期10卷 121-130页

作者： dae kun kwon Ahsan KAREEM Deepak KUMAR Yukio TAMURA NatHaz Modeling Laboratory Department of Civil & Environmental Engineering & Earth Sciences University of Notre DameNotre Dame IN 46556 USA Department of Ocean Engineering Indian Institute of Technology Madras Chennai 600036 India Department of Architectural Engineering Tokyo Polytechnic University Tokyo 243-0297 Japan

This study presents a development of an advanced cyberbased database-enabled design module for low- rise buildings （DEDM-LR） which provides estimation of the wind-induced responses for main wind force resisting frames by making direct use of pressure time histories measured at a large number of pressure taps over a suite of building models. These responses may be considered in lieu of code-specified load effects in which the overall accuracy may be influenced by the inherent simplifications in codes. In addition, this new automated approach is particularly attractive and advantageous as it allows a web-based online analysis/design via intuitive user-friendly interfaces for both the input and output in terms of familiar web-style forms that are nowadays very common in most of web-based services. Presently, the DEDM-LR hosts an aerodynamic database developed by the Tokyo Polytechnic University （TPU）, Japan for a variety of building configurations like flat, gable, and hip roofs under suburban terrain flow condition with immediate application to other databases. The paper shows the efficacy and validity of the DEDM-LR by walking through its details and examples on selected gable-roofed buildings. The architecture of DEDM-LR platform offers the ability to pool resources by hosting other databases that may become available in the near future.

关键词： wind loads low-rise building pressure measurement aerodynamics building design structural response,building codes information technology (IT)

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Polymeric micelle nanocarriers in cancer research

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Frontiers of Chemical Science and Engineering 2016年第3期10卷 348-359页

作者： dae Hwan Shin Yu Tong Tam Glen S. kwon School of Pharmacy University of Wisconsin Madison WI 53705 USA

Amphiphilic block copolymers （ABCs） assem- ble into a spherical nanoscopic supramolecular core/shell nanostructure termed a polymeric micelle that has been widely researched as an injectable nanocarrier for poorly water-soluble anticancer agents. The aim of this review article is to update progress in the field of drug delivery towards clinical trials, highlighting advances in polymeric micelles used for drug solubilization, reduced off-target toxicity and tumor targeting by the enhanced permeability and retention （EPR） effect. Polymeric micelles vary in stability in blood and drug release rate, and accordingly play different but key roles in drug delivery. For intravenous （IV） infusion, polymeric micelles that disas- semble in blood and rapidly release poorly water-soluble anticancer agent such as paclitaxel have been used for drug solubilization, safety and the distinct possibility of toxicity reduction relative to existing solubilizing agents, e.g., Cremophor EL. Stable polymeric micelles are long- circulating in blood and reduce distribution to non-target tissue, lowering off-target toxicity. Further, they participate in the EPR effect in murine tumor models. In summary, polymeric micelles act as injectable nanocarriers for poorly water-soluble anticancer agents, achieving reduced toxi- city and targeting tumors by the EPR effect.

关键词： nanomedicine parenteral poly(ethylene glycol) poly(lactic acid) reformulation

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Effects of ozonation and coagulation on effluent organic matter characteristics and ultrafiltration membrane fouling

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Journal of Environmental Sciences 2014年第6期26卷 1325-1331页

作者： kwon Jeong dae-Sung Lee Do-Gun Kim Seok-Oh Ko Department of Civil Engineering Kyung Hee UniversityYongin 446-701 Korea Institute of Construction Technology KUMHO Engineering & ConstructionYongin 449-822 Korea

Effluent organic matter （EfOM） is the major cause of fouling in the low pressure membranes process for wastewater reuse. Coagulation and oxidation of biological wastewater treatment effluent have been applied for the fouling control of microfiltration membranes. However, the change in EfOM structure by pre-treatments has not been clearly identified. The changes of EfOM characteristics induced by coagulation and ozonation were investigated through size exclusion chromatography, UV/Vis spectrophotometry, fluorescence spectrophotometry and titrimetric analysis to identify the mechanisms in the reduction of ultrafiltration （UF） membrane fouling. The results indicated that reduction of flux decline by coagulation was due to modified characteristics of dissolved organic carbon （DOC） content. Total concentration of DOC was not reduced by ozonation. However, the mass fraction of the molecules with molecular weight larger than 5 kDa, fluorescence intensity, aromaticity, highly condensed chromophores, average molecular weight and soluble microbial byproducts decreased greatly after ozonation. These results indicated that EfOM was partially oxidized by ozonation to low molecular weight, highly charged compounds with abundant electron- withdrawing functional groups, which are favourable for alleviating UF membrane flux decline.

关键词： effluent organic matter fouling ultrafiltration oxidation molecular weight distribution acidity

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Evaluation of particle growth systems for sampling and analysis of atmospheric fine particles

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Particuology 2011年第6期9卷 606-610页

作者： dae Seong Kim Sang Bum Hong Jung-Taek kwon Kihong Park Department of Environmental Science and Engineering Gwangju Institute of Science and Technology Korea Polar Research Institute Laboratory of Toxicology College of Veterinary Medicine Seoul National University

Three types of water-based condensational growth systems, which can enable particles to grow in size to facilitate sampling and subsequent chemical analysis, were evaluated. The first one is a mixing type growth system where aerosols are mixed with saturated water vapor, the second one is a thermal diffusive growth system where warm flow enters cold-walled tube, and the third one is a laminar flow type where cold flow enters a warm wet-wall tube. Hygroscopic sodium chloride （NaCl）, ammonium sulfate （（NH4）2SO4） and ammonium nitrate （NH4N03）, and non-hygroscopic polystyrene latex （PSL） particles, in the size range of 50-400 nm, were used to determine their growth factors through the growth systems. Our data showed that the third-type growth system could enable particles to grow most efficiently regardless of their hygroscopic property. Collection efficiency of particles in the size range of 0.05-2.5 μm, in a continuous aerosol sampler after they passed through the third-type growth system was about 100%, suggesting that the third-type growth system would he the most useful among the tested growth systems for sampling and subsequent chemical analysis of fine and ultrafine particles.

关键词： Particle growth chamber Condensational growth Particle sampler Hygroscopic particles

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Lubrication properties of silver-palladium alloy prepared by ion plating method for high temperature stud bolt

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 12-16页

作者： Jung-dae kwon Sunghun LEE Koo-Hyun LEE Jong-Joo RHA Kee-Seok NAN Se-Hun kwon Materials Processing Division Korea Institute of Materials Science Changwon Gyeongnam 641-831 Korea National Core Research Center for Hybrid Materials Solution Pusan National University

As a solid lubricant, silver-palladium (Ag-Pd) alloy coating was investigated for the application to high temperature stud bolt. A glue layer nickel (Ni) film was deposited on the surface of the hex bolt sample and then Ag-Pd alloy coating was performed on it using ion plating method. The friction coefficient of Ag-Pd alloy film coated bolt was lower than that of N-5000 oil coated bolt by the result of axial force measurement. The cyclic test of heat treatment was conducted to evaluate the durability of Ag-Pd alloy film coated bolt. In a cycle, sample was assembled into the block using torque wrench, followed by heating and disassembling. It was not successful to disassemble the N-5000 oil coated bolt from the block after only one cycle. However, the Ag-Pd alloy film coated bolt was able to be disassembled softly till 12 cycles.

关键词： solid lubricant silver-palladium alloy ion plating

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Formation of sub-100-nm suspended nanowires with various materials using thermally adjusted electrospun nanofibers as templates

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Microsystems & Nanoengineering 2023年第1期9卷 263-270页

作者： Yongkeun Oh dae-Sung kwon Eunhwan Jo Yunsung Kang Sangjun Sim Jongbaeg Kim School of Mechanical Engineering Yonsei UniversitySeoul03722Republic of Korea

The air suspension and location specification properties of nanowires are crucial factors for optimizing nanowires in electronic devices and suppressing undesirable interactions with *** various strategies have been proposed to fabricate suspended nanowires,placing a nanowire in desired microstructures without material constraints or high-temperature processes remains a *** this study,suspended nanowires were formed using a thermally aggregated electrospun polymer as a *** elaborately designed microstructure enables an electrospun fiber template to be formed at the desired location during thermal ***,the desired thickness of the nanowires is easily controlled with the electrospun fiber templates,resulting in the parallel formation of suspended nanowires that are less than 100 nm ***,this approach facilitates the formation of suspended nanowires with various *** is accomplished by evaporating various materials onto the electrospun fiber template and by removing the ***,copper,tungsten oxide(WO3),and tin oxide nanowires are formed as examples to demonstrate the advantage of this approach in terms of nanowire material ***(H2)and nitrogen dioxide(NO2)gas sensors comprising palladium and tungsten oxide,respectively,are demonstrated as exemplary devices of the proposed method.

关键词： nanowires template fibers

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Adoption of wide-bandgap microcrystalline silicon oxide and dual buffers for semitransparent solar cells in building-integrated photovoltaic window system

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Journal of Materials Science & Technology 2019年第8期35卷 1563-1569页

作者： Johwa Yang Hyunjin Jo Soo-Won Choi Dong-Won Kang Jung-dae kwon Surface Technology Division Korea Institute of Materials ScienceChangwon 641-831 Republic of Korea School of Energy Systems Engineering Chung-Ang UniversitySeoul 06974 Republic of Korea

We focused on developing penetration-type semitransparent thin-film solar cells(STSCs) using hydrogenated amorphous Si(a-Si:H) for a building-integrated photovoltaic(BIPV) window system. Instead of conventional p-type a-Si:H, p-type hydrogenated microcrystalline Si oxide(p-μc-SiOx:H) was introduced for a wide-bandgap and conductive window layer. For these purposes, we tuned the CO2/SiH4 flow ratio(R) during p-μc-SiOx:H deposition. The film crystallinity decreased from 50% to 13% as R increased from 0.2 to 1.2. At the optimized R of 0.6, the quantum efficiency was improved under short wavelengths by the suppression of p-type layer parasitic absorption. The series resistance was well controlled to avoid fill factor loss at R = 0.6. Furthermore, we introduced dual buffers comprising p-a-SiOx:H/i-a-Si:H at the p/i interface to alleviate interfacial energy-band mismatch. The a-Si:H STSCs with the suggested window and dual buffers showed improvements in transmittance and efficiency from 22.9% to 29.3% and from 4.62% to 6.41%, respectively, compared to the STSC using a pristine p-a-Si:H window.

关键词： Microcrystalline silicon oxide Building-integrated photovoltaics Semitransparent Thin film Solar cells

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Some Identities of the Higher-Order Type 2 Bernoulli Numbers and Polynomials of the Second Kind

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Computer Modeling in Engineering & Sciences 2021年第9期128卷 1121-1132页

作者： Taekyun Kim dae SanKim Dmitry V.Dolgy Si-Hyeon Lee Jongkyum kwon Department of Mathematics Kwangwoon UniversitySeoul139-701Korea Department of Mathematics Sogang UniversitySeoul121-742Korea Kwangwoon Glocal Education Center Kwangwoon UniversitySeoul139-701Korea Department of Mathematics Education Gyeongsang National UniversityJinju52828Korea

We introduce the higher-order type 2 Bernoulli numbers and polynomials of the second *** this paper,we investigate some identities and properties for them in connection with central factorial numbers of the second kind and the higher-order type 2 Bernoulli *** give some relations between the higher-order type 2 Bernoulli numbers of the second kind and their conjugates.

关键词： Bernoulli polynomials of the second kind higher-order type 2 Bernoulli polynomials of the second kind higher-order conjugate type 2 Bernoulli polynomials of the second kind

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Entacapone promotes hippocampal neurogenesis in mice

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Neural Regeneration Research 2021年第6期16卷 1005-1010页

作者： dae Young Yoo Hyo Young Jung Woosuk Kim Kyu Ri Hahn Hyun Jung kwon Sung Min Nam Jin Young Chung Yeo Sung Yoon dae Won Kim In Koo Hwang Department of Anatomy and Cell Biology College of Veterinary Medicineand Research Institute for Veterinary ScienceSeoul National UniversitySeoulSouth Korea Department of Anatomy College of MedicineSoonchunhyang UniversityCheonanSouth Korea Department of Biomedical Sciences and Research Institute for Bioscience and BiotechnologyHallym UniversityChuncheonSouth Korea Department of Biochemistry and Molecular Biology Research Institute of Oral SciencesCollege of DentistryGangneung-Wonju National UniversityGangneungSouth Korea Department of Anatomy College of Veterinary MedicineKonkuk UniversitySeoulSouth Korea Department of Veterinary Internal Medicine and Geriatrics College of Veterinary MedicineKangwon National UniversityChuncheonSouth Korea

Entacapone,a catechol-O-methyltransferase inhibitor,can strengthen the therapeutic effects of levodopa on the treatment of Parkinson’s ***,few studies are reported on whether entacapone can affect hippocampal neurogenesis in *** investigate the effects of entacapone,a modulator of dopamine,on proliferating cells and immature neurons in the mouse hippocampal dentate gyrus,60 mice(7 weeks old)were randomly divided into a vehicle-treated group and the groups treated with 10,50,or 200 mg/kg *** results showed that 50 and 200 mg/kg entacapone increased the exploration time for novel object *** staining results revealed that after entacapone treatment,the numbers of Ki67-positive proliferating cells,doublecortin-positive immature neurons,and phosphorylated cAMP response element-binding protein(pCREB)-positive cells were significantly *** blot analysis results revealed that treatment with tyrosine kinase receptor B(TrkB)receptor antagonist significantly decreased the exploration time for novel object recognition and inhibited the expression of phosphorylated TrkB and brain-derived neurotrophic factor(BDNF).Entacapone treatment antagonized the effects of TrkB receptor *** results suggest that entacapone treatment promoted hippocampal neurogenesis and improved memory function through activating the BDNF-TrkB-pCREB *** study was approved by the Institutional Animal Care and Use Committee of Seoul National University(approval ***-130730-1)on February 24,2014.

关键词： brain-derived neurotrophic factor entacapone hippocampus neurogenesis neurotrophic factor phosphorylated cAMP response element-binding protein tyrosine kinase receptor B receptor

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Effect of vehicle weight on natural frequencies of bridges measured from traffic-induced vibration

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Earthquake Engineering and Engineering Vibration 2003年第1期2卷 109-116页

作者： Chul-Young Kim dae-Sung Jung Nam-Sik Kim Soon-Duck kwon Maria Q.Feng Dept.of Civil & Envir.Eng. Myongji UniversityKorea Professor Dept.of Civil & Envir.Eng. Myongji UniversityKorea Research Associate Hyundai Institute of Construction Technology Hyundai E&C Co.Ltd.Korea Chief Researcher Dept.of Civil Engineering Chonbuk National UniversityKorea Professor Dept.of Civil & Envir.Eng. University of CaliforniaIrvineCaliforniaUSA Professor

Recently,ambient vibration test(AVT)is widely used tu estimate dynamic characteristics of large civil struc- *** characteristics ean be affected by various envirnnmental factors such as humidity,intensity of wind,and *** these environmental conditions,tire mass of vehicles may change the measured valnes when traffic-in- duced vibration is used as a source of AVT tor *** effect of vehicle mass on dynamic characteristics is investigated through traffic-induced vibration tests on three bridges;(1)three-span suspension bridge(128m+404m+128m),(2) five-span continuous steel box girder bridge(59m+3@ 95m+59m),(3)simply supported plate girder bridge(46m). Acceleration histories of each measurement location under normal traffic are recorded for 30 minutes at *** recor- ded histories are divided into individual vibrations and are combined into two groups aceording to the level of vibration;one by heavy vehicles such as trucks and buses and the other by light vehicles such as passenger *** processing of the two groups of signals shows that,for the middle and long-span bridges,the difference can be hardly detected,but,for the short span bridges whose mass is relatively small,the measured natural frequencies can change up to 5.4%.

关键词： ambient vibration test traffic induced vibration vehicle mass suspension bridge short-span bridge dynamic characteristics natural frequency

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